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Effects of volume loading and pressor agents in idiopathic orthostatic tachycardia

BACKGROUND: Idiopathic orthostatic tachycardia (IOT) is characterized by an increase in heart rate (HR) with standing of > or = 30 bpm that is associated with elevated catecholamine levels and orthostatic symptoms. A dynamic orthostatic hypovolemia and alpha1-adrenoreceptor hypersensitivity have been demonstrated in IOT patients. There is evidence of an autonomic neuropathy affecting the lower-extremity blood vessels. METHODS AND RESULTS: We studied the effects of placebo, the alpha1-adrenoreceptor agonist midodrine (5 to 10 mg), the alpha2-adrenoreceptor agonist clonidine (0.1 mg), and I.V. saline (1 L) in 13 patients with IOT. Supine and upright blood pressure (BP) and HR were measured before and at 1 and 2 hours after intervention. Midodrine decreased both supine and upright HR (all HR values are given as bpm) at 2 hours (from 78+/-2 supine to 108+/-5 upright before treatment and from 69+/-2 supine to 95+/-5 upright after treatment, P<.005 for supine and P<.01 for upright). Saline decreased both supine and upright HR (from 80+/-3 supine to 112+/-5 upright before infusion and from 77+/-3 supine to 91+/-3 upright 1 hour after infusion, P<.005 for supine and P<.001 for upright). Clonidine decreased supine HR (from 78+/-2 to 74+/-2, P<.03) but did not affect the HR increase with standing. Clonidine very significantly decreased supine systolic BP (from 109+/-3 at baseline to 99+/-2 mm Hg at 2 hours, P<.001), and midodrine decreased supine systolic BP mildly. CONCLUSIONS: IOT responds best acutely to saline infusion to correct the underlying hypovolemia. Chronically, this can be accomplished with increased salt and water intake in conjunction with fludrocortisone. The response of patients to the alpha1-agonist midodrine supports the hypothesis of partial dysautonomia and indicates that the use of alpha1-agonists to pharmacologically replace lower-extremity postganglionic sympathetics is an appropriate overall goal of therapy. These findings are consistent with our hypothesis that the tachycardia and elevated catecholamine levels associated with IOT are principally due to hypovolemia and loss of adequate lower-extremity vascular tone.

Non-NASA Center↗

How Effective Is Communication Training For Aircraft Crews

Report surveys communication training for aircraft crews. Intended to alleviate problems caused or worsened by poor communication and coordination among crewmembers. Focuses on two training methods: assertiveness training and grid-management training. Examines theoretical background of methods and attempts made to validate their effectiveness. Presents criteria for evaluating applicability to aviation environment. Concludes communication training appropriate for aircraft crews.

Linde, Charlotte↗

A comparative study of Higgs boson production from vector-boson fusion

The data taken in Run II at the Large Hadron Collider have started to probe Higgs boson production at high transverse momentum. Future data will provide a large sample of events with boosted Higgs boson topologies, allowing for a detailed understanding of electroweak Higgs boson plus two-jet production, and in particular the vector-boson fusion mode (VBF). We perform a detailed comparison of precision calculations for Higgs boson production in this channel, with particular emphasis on large Higgs boson transverse momenta, and on the jet radius dependence of the cross section. We study fixed-order predictions at next-to-leading order and next-to-next-to-leading order QCD, and compare the results to NLO plus parton shower (NLOPS) matched calculations. The impact of the NNLO corrections on the central predictions is mild, with inclusive scale uncertainties of the order of a few percent, which can increase with the imposition of kinematic cuts. We find good agreement between the fixed-order and matched calculations in non-Sudakov regions, and the various NLOPS predictions also agree well in the Sudakov regime. We analyze backgrounds to VBF Higgs boson production stemming from associated production, and from gluon-gluon fusion. At high Higgs boson transverse momenta, the Δy$_{jj}$ and/or m$_{jj}$ cuts typically used to enhance the VBF signal over background lead to a reduced efficiency. We examine this effect as a function of the jet radius and using different definitions of the tagging jets. QCD radiative corrections increase for all Higgs production modes with increasing Higgs boson p$_{T}$, but the proportionately larger increase in the gluon fusion channel results in a decrease of the gluon-gluon fusion background to electroweak Higgs plus two jet production upon requiring exclusive two-jet topologies. We study this effect in detail and contrast in particular a central jet veto with a global jet multiplicity requirement.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Cluster Observations for Combined X-Ray and Sunyaev-Zel'dovich Estimates of Peculiar Velocities and Distances

Measurements of the peculiar velocities of galaxy clusters with respect to the Hubble flow allow the determination of the gravitational field from all matter in the universe, not just the visible component. The Sunyaev-Zel'dovich (SZ) effect (the inverse-Compton scattering of cosmic microwave background photons by the hot gas in clusters of galaxies) allows these velocities to be measured without the use of empirical distance indicators. Additionally, because the magnitude of the SZ effect is independent of redshift, the technique can be used to measure velocities out to the epoch of cluster formation. The SZ technique requires a determination of the temperature of the hot cluster gas from X-ray observations, and measurements of the SZ effect at millimeter wavelengths to separate the contribution from the thermal motions within the gas from that of the cluster peculiax velocity. We have constructed a bolometric receiver, the Sunyaev-Zel'dovich Infrared Experiment, specifically to make measurements of the SZ effect at millimeter wavelengths in order to apply the SZ technique to peculiar velocity measurements. This receiver has already been used to set limits to the peculiar velocities of two galaxy clusters at z approx. 0.2. As a test of the SZ technique, the double cluster pair Abell 222 and 223 was selected for observation. Measurements of the redshifts of the two components suggest that, if the clusters are gravitationally bound, they should exhibit a relative velocity of 10OO km/ s, well above the expected precision of 200 km/ s (set by astrophysical confusion) that is expected from the SZ method. The temperature can be measured from ASCA data which we obtained for this cluster pair. However, in order to ensure that the temperature estimate from the ASCA data was not dominated by cooling flows within the cluster, we requested ROSAT HRI observations of this cluster pair. Analysis of the X-ray properties of the cluster pair is continuing by combining the ROSAT observations funded under this proposal, archival PSPC data and our own PI ASCA data. The imaging data shows that neither cluster has a strong cooling flow, although A223 is the more compact of the two components. A223 also has a sub-cluster projected 1 Mpc to the North. The observed properties of this cluster pair are strikingly similar to those of the well-studied pair of A399 and A401 which are widely believed to be interacting and are in the initial stages of merging. This strengthens our selection of this cluster pair as a test for cluster peculiar motions. Combining these X-ray observations with SUZIE measurements of the SZ effect will provide important constraints on cluster merger models. This part of the program has been heavily delayed by bad weather at Mauna Kea, however SZ observations were obtained in November 1997 as part of a separately funded effort. These data are currently being analyzed.

Lange, A. E.↗

Independent and interactive effects of wet bulb globe temperature and air pollution exposures on suicide mortality

Background: Individual components of the ambient environment, such as temperature and air pollution, exist as part of a complex mixture and have been associated with suicide; however, their interactive effects remain poorly understood. This study examined the independent and interactive effects of wet bulb globe temperature (WBGT), nitrogen dioxide (NO 2 ), and fine particulate matter (PM 2.5 ) on suicide mortality. Methods: We identified 7,551 suicide cases in Utah, USA, from 2000 to 2016 and assigned exposure to daily maximum WBGT (sourced from the European Center for Medium-Range Weather Forecasts) and PM 2.5 and NO 2 concentrations (sourced from a national spatiotemporal ensemble model) using decedent’s residential address at the time of death. A case-crossover design with conditional logistic regression was used to estimate the independent and interactive effects of WBGT max , PM 2.5 , and NO 2 on suicide. For exposure windows, we considered single days preceding suicide (lag 0 to 6) and their averages across preceding days (lag 0–1, 0–3, and 0–6). Analyses were stratified by season. Results: We identified a significant association between WBGT max and suicide across all seasons (odds ratio [OR] = 1.05, 95% confidence interval [CI]: 1.01, 1.10; per 5 °C increase on lag 0–3 days). The associations were stronger in the warm season (March 22 to September 21), with ORs and 95% CIs ranging from 1.08 (1.02, 1.15) to 1.20 (1.10, 1.30) per 5 °C increase depending on the lag periods. We observed synergistic interactions between WBGT max and PM 2.5 and NO 2 in the warm season, associated with higher odds of suicide. The associations of WBGT max with suicide were most pronounced at high NO 2 levels. Conclusions: We found evidence of synergistic interactions between WBGT max and PM 2.5 and NO 2 on suicide in the warm season, emphasizing the need for considering the combined effects of heat stress and air pollution in suicide prevention strategies.

Fine particulate matter↗

Fast neutron background characterization of the future Ricochet experiment at the ILL research nuclear reactor

Abstract The future Ricochet experiment aims at searching for new physics in the electroweak sector by providing a high precision measurement of the Coherent Elastic Neutrino-Nucleus Scattering (CENNS) process down to the sub-100 eV nuclear recoil energy range. The experiment will deploy a kg-scale low-energy-threshold detector array combining Ge and Zn target crystals 8.8 m away from the 58 MW research nuclear reactor core of the Institut Laue Langevin (ILL) in Grenoble, France. Currently, the Ricochet Collaboration is characterizing the backgrounds at its future experimental site in order to optimize the experiment’s shielding design. The most threatening background component, which cannot be actively rejected by particle identification, consists of keV-scale neutron-induced nuclear recoils. These initial fast neutrons are generated by the reactor core and surrounding experiments (reactogenics), and by the cosmic rays producing primary neutrons and muon-induced neutrons in the surrounding materials. In this paper, we present the Ricochet neutron background characterization using $$^3$$ 3 He proportional counters which exhibit a high sensitivity to thermal, epithermal and fast neutrons. We compare these measurements to the Ricochet Geant4 simulations to validate our reactogenic and cosmogenic neutron background estimations. Eventually, we present our estimated neutron background for the future Ricochet experiment and the resulting CENNS detection significance. Our results show that depending on the effectiveness of the muon veto, we expect a total nuclear recoil background rate between 44 ± 3 and 9 ± 2 events/day/kg in the CENNS region of interest, i.e. between 50 eV and 1 keV. We therefore found that the Ricochet experiment should reach a statistical significance of 4.6 to 13.6 $$\sigma $$ σ for the detection of CENNS after one reactor cycle, when only the limiting neutron background is considered.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Building a Diverse and Inclusive STEM Workforce: The JUMP into STEM Program: Preprint

The JUMP into STEM program is a DOE-funded initiative jointly run by the National Renewable Energy Laboratory and Oak Ridge National La-boratory. Through this program, students from historically underrepresented backgrounds are engaged in the science of building energy-efficient infrastruc-ture. Through program stages, students have opportunity to compete in chal-lenges, competitions, and internship opportunities. We have conducted a study of past participants in the program. We find that 1) the program has been effec-tive at engaging a diverse array of participants from a variety of backgrounds, including historically underrepresented backgrounds, and 2) the program has been effective at promoting career paths in STEM, and more specifically, in en-ergy efficiency.

DEI↗

Probing lepton flavor violation at Circular Electron-Positron Colliders

Lepton flavor violation is one of the cleanest probes of physics beyond the standard model. In this work, we explore the sensitivity of the process e + e – → τμ to new physics above the TeV scale at the proposed circular electron-positron colliders FCC-ee and CEPC. We compute the e + e – → τμ cross-section in the Standard Model Effective Field Theory and assess the relevant backgrounds. We compare our sensitivity projections to existing and expected constraints from tau decays and Z decays and find that the future electron-positron colliders provide competitive probes of new physics. We highlight the complementarity of searches for resonant e + e – → Z → τμ production on the Z pole and searches for non-resonant e + e – → τμ at higher center-of-mass energies.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Development and Field Assessment of Transgenic Hybrid Switchgrass for Improved Biofuel Traits

Development of commercially relevant bioenergy switchgrass cultivars requires reducing recalcitrance for bioprocessing without compromising biomass yield. Low-lignin transgenic switchgrass has been produced via down-regulation of caffeic acid O-methyltransferase (COMT), a lignin biosynthetic enzyme, or by over-expression of the MYB4 transcription factor, a repressor of the lignin biosynthetic pathway. The aim of this study was to evaluate parents and selected hybrids obtained from COMT and MYB4 hybrid families under field conditions for agronomic performance and biomass quality. Plant height, width, number of tillers, dry weight, cell wall composition including lignin content, and sugar release were measured after the establishment year (2014) and the second growing season (2015). For COMT hybrids, biomass yield of the transgenic hybrids was similar to or greater than the wild-type parents selected for high biomass. Lignin content of COMT transgenic hybrids was reduced by 10%, S/G ratio decreased by 27%, and sugar release increased between 20% and 44% compared to their wild-type parents. These results indicate that hybridization of COMT with a high-yielding locally selected genotype resulted in both improved agronomic performance and enhanced biomass quality in the offspring. On the other hand, the MYB transgenic hybrid showed a 10% reduction in biomass yield compared with its wild-type parent in year 1, but not in year 2. The lignin S/G ratio was not reduced in MYB transgenic hybrids, nor was sugar release increased. These data indicate that the MYB transgene may not be suitable for an agronomic setting. More testing is needed of transgenic and wild-type, high-biomass selections for use as breeding parents. These results show that combining low-lignin transgenic switchgrass with a breeding and selection program for biomass yield will allow for the deployment of effective transgenes in high-yielding genetic backgrounds.

09 BIOMASS FUELS↗

Sheath transitions in a cylindrical filament discharge: Axisymmetric 1D3V PIC-MCC simulations

We present the first nonplanar hot cathode discharge simulations that capture the role of the trapped-ions plasma, elucidating new phenomena unobservable in planar geometric discharges. A discharge struck between a single emitting wire filament cathode and a bounding anode is simulated in cylindrical geometry using an axisymmetric (radial) particle-in-cell Monte-Carlo collisions code. Operating the discharge near its ionization energy threshold can lead to the formation of a two plasma mode (TPM). One plasma forms in the conventional upstream region through electron impact ionization of background neutrals. A second plasma, whose global effect on the discharge was not previously well understood, forms downstream through the trapping of cold ions in the potential well of the filament’s virtual cathode, a process enabled by ion-neutral charge exchange collisions. Three space charge regions intersperse the electrode gap—an emissive sheath between the cathode filament and trapped-ions plasma, a double layer between the two plasmas, and a classical sheath between the upstream plasma and the outer anode. Simulations exhibit mode transitions and quenching instabilities that transform the discharge between the TPM and other single-plasma sheath modes that include classical (temperature-limited), space charge limited, and inverse (anode glow) modes. The transitions are explained via “aid-and-compete” dynamics wherein the growth of one plasma enhances growth in the other while concurrently exhibiting expansion dynamics antagonistic to each other. The system exhibits strong hysteresis memory during the mode transitions. Improved understanding and control of these sheath mode transitions are expected to benefit plasma applications with hot cathodes.

Electrical hysteresis↗

Stability of hairy black holes in shift-symmetric scalar-tensor theories via the effective field theory approach

Shift-symmetric Horndeski theories admit an interesting class of Schwarzschild-de Sitter black hole solutions exhibiting time-dependent scalar hair. The properties of these solutions may be studied via a bottom-up effective field theory (EFT) based on the background symmetries. This is in part possible by making use of a convenient coordinate choice — Lemaître-type coordinates — in which the profile of the Horndeski scalar field is linear in the relevant time coordinate. We construct this EFT, and use it to understand the stability of hairy black holes in shift-symmetric Horndeski theories, providing a set of constraints that the otherwise-free functions appearing in the Horndeski Lagrangian must satisfy in order to admit stable black hole solutions. The EFT is analyzed in the decoupling limit to understand potential sources of instability. Further, we also perform a complete analysis of the EFT with odd-parity linear perturbations around general spherically symmetric space-time.

79 ASTRONOMY AND ASTROPHYSICS↗

Improving constraints on models addressing the Hubble tension with CMB delensing

The Hubble Tension is a well-known issue in modern cosmology that refers to the apparent disagreement in inferences of the Hubble constant H 0 as found through low-redshift observations and those derived from the ΛCDM model utilizing early universe observations. Several extensions to ΛCDM have been proposed to address the Hubble Tension that involve new ingredients or dynamics in the early universe. Reversing the effects of gravitational lensing on cosmic microwave background (CMB) maps produces sharper acoustic peaks in power spectra and allows for tighter constraints on cosmological parameters. We investigate the efficacy of CMB delensing for improving the constraints on parameters used in extensions of the ΛCDM model that are aimed at resolving the Hubble Tension (such as varying fundamental constants, contributions from early dark energy, and self-interacting dark radiation). We use Fisher forecasting to predict the expected constraints with and without this delensing procedure. We demonstrate that CMB delensing improves constraints on H 0 by ~ 20% for viable models and significantly improves constraints on parameters across the board in the low-noise regime.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Chiral kinetic theory of anomalous transport induced by torsion

In Weyl semimetals subjected to torsion, there are two different kinds of chirality: (i) The (coordinate-space) shape of the twisted crystal is chiral and (ii) the momentum space contains chiral quasiparticles. Here we construct a general kinetic theory of anomalous transport using the phase space (coordinate and momentum spaces combined) Berry curvature induced by torsion in Weyl systems. We describe how torsion generates the chiral chemical potential and thus leads to the chiral magnetic effect (CME) in the presence of a background magnetic field. We propose to measure the CME current induced by the torsion as a way to detect the anomalous coupling between the coordinate-space and momentum-space chiralities.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Masses of Sunyaev-Zel’dovich galaxy clusters detected by the Atacama Cosmology Telescope: Stacked lensing measurements with Subaru HSC year 3 data

We present a stacked lensing analysis of 96 galaxy clusters selected by the thermal Sunyaev-Zel’dovich (SZ) effect in maps of the cosmic microwave background (CMB). We select foreground galaxy clusters with a 5 σ -level SZ threshold in CMB observations from the Atacama Cosmology Telescope, while we define background source galaxies for the lensing analysis with secure photometric redshift cuts in Year 3 data of the Subaru Hyper Suprime Cam survey. We detect the stacked lensing signal in the range of 0.1 < R [ h - 1 Mpc ] < 100 in each of three cluster redshift bins, 0.092 < z ≤ 0.445 , 0.445 < z ≤ 0.695 , and 0.695 < z ≤ 1.180 , with 32 galaxy clusters in each bin. The cumulative signal-to-noise ratios of the lensing signal are 14.6, 12.0, and 6.6, respectively. Using a halo-based forward model, we then constrain statistical relationships between the mass inferred from the SZ observation (i.e. SZ mass) and the total mass derived from our stacked lensing measurements. At the average SZ mass in the cluster sample ( 2.1 - 2.4 × 10 14 h - 1 M ⊙ ), our likelihood analysis shows that the average total mass differs from the SZ counterpart by a factor of 1.3 ± 0.2 , 1.6 ± 0.2 , and 1.6 ± 0.3 (68%) in the aforementioned redshift ranges, respectively. Our limits are consistent with previous lensing measurements, and we find that the cluster modeling choices can introduce a 1 σ -level difference in our parameter inferences.

79 ASTRONOMY AND ASTROPHYSICS↗

Persistent memory as an effective alternative to random access memory in metagenome assembly

Abstract Background The assembly of metagenomes decomposes members of complex microbe communities and allows the characterization of these genomes without laborious cultivation or single-cell metagenomics. Metagenome assembly is a process that is memory intensive and time consuming. Multi-terabyte sequences can become too large to be assembled on a single computer node, and there is no reliable method to predict the memory requirement due to data-specific memory consumption pattern. Currently, out-of-memory (OOM) is one of the most prevalent factors that causes metagenome assembly failures. Results In this study, we explored the possibility of using Persistent Memory (PMem) as a less expensive substitute for dynamic random access memory (DRAM) to reduce OOM and increase the scalability of metagenome assemblers. We evaluated the execution time and memory usage of three popular metagenome assemblers (MetaSPAdes, MEGAHIT, and MetaHipMer2) in datasets up to one terabase. We found that PMem can enable metagenome assemblers on terabyte-sized datasets by partially or fully substituting DRAM. Depending on the configured DRAM/PMEM ratio, running metagenome assemblies with PMem can achieve a similar speed as DRAM, while in the worst case it showed a roughly two-fold slowdown. In addition, different assemblers displayed distinct memory/speed trade-offs in the same hardware/software environment. Conclusions We demonstrated that PMem is capable of expanding the capacity of DRAM to allow larger metagenome assembly with a potential tradeoff in speed. Because PMem can be used directly without any application-specific code modification, these findings are likely to be generalized to other memory-intensive bioinformatics applications.

59 BASIC BIOLOGICAL SCIENCES↗

Modeling spatial patterns of longleaf pine needle dispersal using long-term data

Abstract Background Predicting patterns of fire behavior and effects in frequent fire forests relies on an understanding of fine-scale spatial patterns of available fuels. Leaf litter is a significant canopy-derived fine fuel in fire-maintained forests. Litter dispersal is dependent on foliage production, stand structure, and wind direction, but the relative importance of these factors is unknown. Results Using a 10-year litterfall dataset collected within eighteen 4-ha longleaf pine ( Pinus palustris Mill.) plots varying in canopy spatial pattern, we compared four spatially explicit models of annual needle litter dispersal: a model based only on basal area, an overstory abundance index (OAI) model, both isotropic and anisotropic litter kernel models, and a null model that assumed no spatial relationship. The best model was the anisotropic model (R 2 = 0.656) that incorporated tree size, location, and prevailing wind direction, followed by the isotropic model (R 2 = 0.612), basal area model (R 2 = 0.488), OAI model (R 2 = 0.416), and the null model (R 2 = 0.08). Conclusions As with previous studies, the predictive capability of the litter models was robust when internally validated with a subset of the original dataset (R 2 = 0.196–0.549); however, the models were less robust when challenged with an independent dataset (R 2 = 0.122–0.319) from novel forest stands. Our model validation underscores the need for rigorous tests with independent, external datasets to confirm the validity of litter dispersal models. These models can be used in the application of prescribed fire to estimate fuel distribution and loading, as well as aid in the fine tuning of fire behavior models to better understand fire outcomes across a range of forest canopy structures.

54 ENVIRONMENTAL SCIENCES↗

Circulating levels of micronutrients and risk of osteomyelitis: a Mendelian randomization study

Background Few observational studies have investigated the effect of micronutrients on osteomyelitis, and these findings are limited by confounding and conflicting results. Therefore, we conducted Mendelian randomization (MR) analyses to evaluate the association between blood levels of eight micronutrients (copper, selenium, zinc, vitamin B12, vitamin C, and vitamin D, vitamin B6, vitamin E) and the risk of osteomyelitis. Methods We performed the two-sample and multivariable Mendelian randomization (MVMR) to investigate causation, where instrument variables for the predictor (micronutrients) were derived from the summary data of micronutrients from independent cohorts of European ancestry. The outcome instrumental variables were used from the summary data of European-ancestry individuals ( n = 486,484). The threshold of statistical significance was set at p < 0.00625. Results We found a significant causal association that elevated zinc heightens the risk of developing osteomyelitis in European ancestry individuals OR = 1.23 [95% confidence interval (CI) [1.07, 1.43]; p = 4.26E-03]. Similarly, vitamin B6 showed a similar significant causal effect on osteomyelitis as a risk factor OR = 2.78 (95% CI [1.34, 5.76]; p = 6.04E-03; in the secondary analysis). Post-hoc analysis suggested this result (vitamin B6). However, the multivariable Mendelian randomization (MVMR) provides evidence against the causal association between zinc and osteomyelitis OR = 0.98(95% CI [−0.11, 0.07]; p = 7.20E-1). After searching in PhenoScanner, no SNP with confounding factors was found in the analysis of vitamin B6. There was no evidence of a reverse causal impact of osteomyelitis on zinc and vitamin B6. Conclusion This study supported a strong causal association between vitamin B6 and osteomyelitis while reporting a dubious causal association between zinc and osteomyelitis.

Zhang, Xu↗

On Black Holes as Macroscopic Quantum Objects

The relative flow of the Schwarzschild vs. the proper time during the classical evolution of a collapsing shell in the Schwarzschild coordinates practically forces us to interpret black hole formation as a highly non-local quantum process in which a shell/anti-shell pair is created within the incipient horizon, thus canceling out the original collapsing shell exactly at the horizon. By studying quantum fields in the black hole background, we reveal similar non-local effects. Among other things, the outgoing member of the Hawking pair very quickly becomes entangled with the black hole geometry (and not its partner), which is in contrast with the usual assumption that the Hawking pair is maximally entangled according to the local geometry near the horizon. Also, an infalling wave affects the black hole geometry even before it crosses the horizon. Finally, we find that a particle takes a finite amount of time to tunnel in and out of the black hole horizon, and thus avoids infinite blue and redshift in processes happening exactly at the horizon. These findings strongly support the picture of a black hole as a macroscopic quantum object.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗