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Results for “Component effects”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 667 records · Page 37
All sourcesNASA NTRSDOE OSTI
DOE OSTI2016

Transfer of a Catabolic Pathway for Chloromethane in Methylobacterium Strains Highlights Different Limitations for Growth with Chloromethane or with Dichloromethane

Chloromethane is an ozone-depleting gas, produced predominantly from natural sources, that provides an important environmental niche for microbes capable of consuming it. Chloromethane catabolism has been difficult to study owing to the challenging genetics of its native microbial hosts. Since the pathways for chloromethane catabolism show evidence of horizontal gene transfer, we reproduced this transfer process in the laboratory to generate new chloromethane-catabolizing strains in tractable hosts. Here, we demonstrate that six putative accessory genes improve chloromethane catabolism, though heterologous expression of only one of the six is strictly necessary for growth on chloromethane. In contrast to growth of Methylobacterium strains with the closely-related compound dichloromethane, we find that chloride export does not limit growth on chloromethane and, in general, that the ability of a strain to grow on dichloromethane is uncorrelated with its ability to grow on chloromethane. Finally, this heterologous expression system allows us to investigate the components required for effective chloromethane catabolism and the factors that limit effective catabolism after horizontal transfer.

59 BASIC BIOLOGICAL SCIENCES↗
DOE OSTI2022

Evolutionary Origins of Metabolic Reprogramming in Cancer

Metabolic changes that facilitate tumor growth are one of the hallmarks of cancer. These changes are not specific to tumors but also take place during the physiological growth of tissues. Indeed, the cellular and tissue mechanisms present in the tumor have their physiological counterpart in the repair of tissue lesions and wound healing. These molecular mechanisms have been acquired during metazoan evolution, first to eliminate the infection of the tissue injury, then to enter an effective regenerative phase. Cancer itself could be considered a phenomenon of antagonistic pleiotropy of the genes involved in effective tissue repair. Cancer and tissue repair are complex traits that share many intermediate phenotypes at the molecular, cellular, and tissue levels, and all of these are integrated within a Systems Biology structure. Complex traits are influenced by a multitude of common genes, each with a weak effect. This polygenic component of complex traits is mainly unknown and so makes up part of the missing heritability. Here, we try to integrate these different perspectives from the point of view of the metabolic changes observed in cancer.

60 APPLIED LIFE SCIENCES↗
DOE OSTI2016

BOLOMETRIC FLUX ESTIMATION FOR COOL EVOLVED STARS

Estimation of bolometric fluxes (F{sub BOL}) is an essential component of stellar effective temperature determination with optical and near-infrared interferometry. Reliable estimation of F{sub BOL} simply from broadband K-band photometry data is a useful tool in those cases were contemporaneous and/or wide-range photometry is unavailable for a detailed spectral energy distribution (SED) fit, as was demonstrated in Dyck et al. Recalibrating the intrinsic F{sub BOL} versus observed F{sub 2.2μm} relationship of that study with modern SED fitting routines, which incorporate the significantly non-blackbody, empirical spectral templates of the INGS spectral library (an update of the library in Pickles) and estimation of reddening, serves to greatly improve the accuracy and observational utility of this relationship. We find that F{sub BOL} values predicted are roughly 11% less than the corresponding values predicted in Dyck et al., indicating the effects of SED absorption features across bolometric flux curves.

79 ASTRONOMY AND ASTROPHYSICS↗
DOE OSTI2017

Coevality in Young Eclipsing Binaries

The ages of the components in very short period pre-main-sequence (PMS) binaries are essential to an understanding of their formation. We considered a sample of seven PMS eclipsing binaries (EBs) with ages 1–6.3 MY and component masses 0.2–1.4 M{sub ⊙}. The very high precision with which their masses and radii have been measured and the capability provided by the Modules for Experiments in Stellar Astrophysics to calculate their evolutionary tracks at exactly the measured masses allows the determination of age differences of the components independent of their luminosities and effective temperatures. We found that the components of five EBs, ASAS J052821+0338.5, Parenago 1802, JW 380, CoRoT 223992193, and UScoCTIO 5, formed within 0.3 MY of each other. The parameters for the components of V1174 Ori imply an implausible large age difference of 2.7 MY and should be reconsidered. The seventh EB in our sample, RX J0529.4+0041 fell outside the applicability of our analysis.

79 ASTRONOMY AND ASTROPHYSICS↗
DOE OSTI2017

Plume-exit modeling to determine cloud condensation nuclei activity of aerosols from residential biofuel combustion

Abstract. Residential biofuel combustion is an important source of aerosols and gases in the atmosphere. The change in cloud characteristics due to biofuel burning aerosols is uncertain, in part, due to the uncertainty in the added number of cloud condensation nuclei (CCN) from biofuel burning. We provide estimates of the CCN activity of biofuel burning aerosols by explicitly modeling plume dynamics (coagulation, condensation, chemical reactions, and dilution) in a young biofuel burning plume from emission until plume exit, defined here as the condition when the plume reaches ambient temperature and specific humidity through entrainment. We found that aerosol-scale dynamics affect CCN activity only during the first few seconds of evolution, after which the CCN efficiency reaches a constant value. Homogenizing factors in a plume are co-emission of semi-volatile organic compounds (SVOCs) or emission at small particle sizes; SVOC co-emission can be the main factor determining plume-exit CCN for hydrophobic or small particles. Coagulation limits emission of CCN to about 1016 per kilogram of fuel. Depending on emission factor, particle size, and composition, some of these particles may not activate at low supersaturation (ssat). Hygroscopic Aitken-mode particles can contribute to CCN through self-coagulation but have a small effect on the CCN activity of accumulation-mode particles, regardless of composition differences. Simple models (monodisperse coagulation and average hygroscopicity) can be used to estimate plume-exit CCN within about 20 % if particles are unimodal and have homogeneous composition, or when particles are emitted in the Aitken mode even if they are not homogeneous. On the other hand, if externally mixed particles are emitted in the accumulation mode without SVOCs, an average hygroscopicity overestimates emitted CCN by up to a factor of 2. This work has identified conditions under which particle populations become more homogeneous during plume processes. This homogenizing effect requires the components to be truly co-emitted, rather than sequentially emitted.

54 ENVIRONMENTAL SCIENCES↗
NASA NTRS1968

Rotation of the solar wind plasma.

Sun rotation effect on azimuthal components of solar wind velocity and interplanetary magnetic field, solving angular momentum equation coupled with Maxwell equations

Alfonso-Faus, A.↗
NASA NTRS1972

Circuit Controls Turn-On Current

Single choke used in primary circuit with diode arrangement, maintaining dc current flow through choke and setting up a unidirectional magnetic field, limits turn-on current of transformer-rectifier power supply. Technique reduces number and weight of components and minimizes effect of initial inrush surge current on source.

Holmes, K. G.↗
NASA NTRS1971

Shuttle cryogenic supply system optimization study

Technical information on different cryogenic supply systems is presented for selecting representative designs. Parametric data and sensitivity studies, and an evaluation of related technology status are included. An integrated mathematical model for hardware program support was developed. The life support system, power generation, and propellant supply are considered. The major study conclusions are the following: Optimum integrated systems tend towards maximizing liquid storage. Vacuum jacketing of tanks is a major effect on integrated systems. Subcritical storage advantages over supercritical storage decrease as the quantity of propellant or reactant decreases. Shuttle duty cycles are not severe. The operational mode has a significant effect on reliability. Components are available for most subsystem applications. Subsystems and components require a minimum amount of technology development.

Source record↗
NASA NTRS1972

Long life assurance study for manned spacecraft long life hardware. Volume 4: Special long life assurance studies

Guidelines for the selection of equipment to be used for manned spacecraft in order to assure a five year maintenance-free service life were developed. A special study was conducted to determine the adequacy of the procedures used to determine the quality and effectiveness of various components. The subjects examined are: (1) temperature cycling for acceptance of electronic assemblies; (2) accelerated testing techniques; (3) electronic part screening techniques; (4) electronic part derating practices; (5) vibration life extension of printed circuit board assemblies; and (6) tolerance funnelling and test requirements.

Source record↗
NASA NTRS1974

Results of investigations on a 0.015-scale model (49-0) of the space shuttle orbiter in the NASA/Ames 3.5-foot hypersonic wind tunnel (OA87)

Experimental aerodynamic investigations were conducted on a scale model of the space shuttle orbiter, Configuration 140A/B. The objectives of this test were to: 1) verify supersonic stability and control characteristics, 2) analyze aerodynamic problem areas, 3) verify control surface effectiveness, and 4) investigate Reynolds number effects. Six-component aerodynamic force and moment data were recorded over an angle of attack range from 22 deg to 46 deg at a constant sideslip angle of 0 deg. The test Mach number was varied from 5.3 to 7.3 to 10.3. The Reynolds number per unit length was varied from 805,000 to 10 million per foot.

Petrozzi, M. T.↗
NASA NTRS1973

LOX/GOX sensitivity of fluoroelastomers

The effect of formulation components and the addition of fire retardants on the impact sensitivity of Viton B fluoroelastomer in liquid oxygen was studied with the objective of developing a procedure for reliably reducing this sensitivity. Component evaluation, carried out on more than 40 combinations of components and cure cycles, showed that almost all the standard formulation agents, including carbon, MgO, Diak-3, and PbO2, will sensitize the Viton stock either singly or in combinations, some combinations being much more sensitive than others. Cure and postcure treatments usually reduced the sensitivity of a given formulation, often dramatically, but no formulated Viton was as insensitive as the pure Viton B stock. Coating formulated Viton with a thin layer of pure Viton gave some indication of reduced sensitivity, but additional tests are needed. It is concluded that sensitivity in formulated Viton arises from a variety of sources, some physical and some chemical in origin. Elemental analyses for all the formulated Vitons are reported as are the results of a literature search on the subject of LOX impact sensitivity.

Kirshen, N.↗
NASA NTRS1974

Many-particle theory of nuclear systems with application to neutron star matter

The energy-density relation was calculated for pure neutron matter in the density range relevant for neutron stars, using four different hard-core potentials. Calculations are also presented of the properties of the superfluid state of the neutron component, along with the superconducting state of the proton component and the effects of polarization in neutron star matter.

Chakkalakal, D. A.↗