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At least 667 records · Page 37

The Integrated Medical Model: A Probabilistic Simulation Model for Predicting In-Flight Medical Risks

The Integrated Medical Model (IMM) is a probabilistic model that uses simulation to predict mission medical risk. Given a specific mission and crew scenario, medical events are simulated using Monte Carlo methodology to provide estimates of resource utilization, probability of evacuation, probability of loss of crew, and the amount of mission time lost due to illness. Mission and crew scenarios are defined by mission length, extravehicular activity (EVA) schedule, and crew characteristics including: sex, coronary artery calcium score, contacts, dental crowns, history of abdominal surgery, and EVA eligibility. The Integrated Medical Evidence Database (iMED) houses the model inputs for one hundred medical conditions using in-flight, analog, and terrestrial medical data. Inputs include incidence, event durations, resource utilization, and crew functional impairment. Severity of conditions is addressed by defining statistical distributions on the dichotomized best and worst-case scenarios for each condition. The outcome distributions for conditions are bounded by the treatment extremes of the fully treated scenario in which all required resources are available and the untreated scenario in which no required resources are available. Upon occurrence of a simulated medical event, treatment availability is assessed, and outcomes are generated depending on the status of the affected crewmember at the time of onset, including any pre-existing functional impairments or ongoing treatment of concurrent conditions. The main IMM outcomes, including probability of evacuation and loss of crew life, time lost due to medical events, and resource utilization, are useful in informing mission planning decisions. To date, the IMM has been used to assess mission-specific risks with and without certain crewmember characteristics, to determine the impact of eliminating certain resources from the mission medical kit, and to design medical kits that maximally benefit crew health while meeting mass and volume constraints.

Risk Analysis↗

Partial equilibrium model for predicting concentration of CO in combustion

A simple kinetic model, based upon the concept of partial equilibrium, is developed for predicting carbon monoxide concentrations in such steady-flow hydrocarbon-air combustion systems as gas-turbine combustors. The only two kinetic constraints used in the model are on the rate of change of the total number of gaseous particles in the system, and on the rate of change of the CO concentration. The accuracy of the model is verified by comparison with experimental results obtained by burning kerosene with air in a 130,000 Btu/hr atmospheric-pressure steady-flow burner. Burnt-gas cooling rates of 1,000,000 K/sec, about the magnitude encountered in the dilution zone of gas-turbine combustors, were obtained with a compact water-cooled heat exchanger. Good agreement between measured CO concentrations and the values predicted by the partial-equilibrium model was obtained.

Morr, A. R.↗

Designer's unified cost model

A conceptual and preliminary designers' cost prediction model has been initiated. The model will provide a technically sound method for evaluating the relative cost of different composite structural designs, fabrication processes, and assembly methods that can be compared to equivalent metallic parts or assemblies. The feasibility of developing cost prediction software in a modular form for interfacing with state of the art preliminary design tools and computer aided design programs is being evaluated. The goal of this task is to establish theoretical cost functions that relate geometric design features to summed material cost and labor content in terms of process mechanics and physics. The output of the designers' present analytical tools will be input for the designers' cost prediction model to provide the designer with a data base and deterministic cost methodology that allows one to trade and synthesize designs with both cost and weight as objective functions for optimization. The approach, goals, plans, and progress is presented for development of COSTADE (Cost Optimization Software for Transport Aircraft Design Evaluation).

Freeman, William T.↗

Steam chugging analysis in single-vent vapor injection

A complete cycle of the periodic steam chugging phenomenon is analyed. Steam velocity and pressure variations in the vent are described by one-dimensional conservation equations. This is coupled either to the water slug model when water is in the vent, or, the infinite pool spherical bubble model at the vent exit during bubble growth. An isolated spherical bubble model is used for computing the collapse pressures. Comparisons of the model predictions with the UCLA 1/12-scale and the Japan 1/6-scale data indicate that the vent-pipe model predicts the vent-clearing times and the bubble growth times well. In addition, the predicted maximum chugging heights compared well with those measured in the Japan data. On bubble collapse pressures, the comparison with the spherical bubble model predictions is only fair. The model generally overpredicts the magnitude of the spikes. On examining the effects of pool subcooling and steam mass flux, general agreement is found between the predicted trends and those measured.

Lee, C. K. B.↗

The Mars Science Laboratory (MSL) MMRTG In-Flight: A Power Update

The MSL Multi-Mission Radioisotope Thermoelectric Generator (MMRTG) was fueled on October 28, 2008 by the Department Of Energy (DOE) in preparation for a late 2009 launch. Shortly after, the MSL launch was delayed approximately 2 years until 2011. The fueled MMRTG was placed in storage to await the new date for liftoff. Occasional measurements of the MMRTG's power output were taken and compared with power predictions that pre-dated fueling. An error in the predictive models was quickly recognized and remedied. The predictions, while improved, carried significant uncertainty. This uncertainty did not deter the launch of MSL, but did alter the planned mission on the surface of Mars. Once launched, the MSL spacecraft provided a hi-fidelity telemetry stream measuring the generator's electrical and thermal performance. These data were used to update the predictive models and a new prediction of the performance of the MMRTG on the surface of Mars was run just before Entry, Descent, and Landing (EDL) at Mars. The MSL MMRTG is working extremely well, providing power above predictions and operating within its flight allowable temperature limits. The generator was producing approximately 114 W at the beginning of the surface mission. This paper will elaborate on power modeling for the MSL MMRTG along with a review of some of the data recorded from the MSL cruise to Mars, EDL, and the early days of the surface mission.

thermoelectric generator↗

Community-wide Validation of Geospace Model Ground Magnetic Field Perturbation Predictions to Support Model Transition to Operations

In this paper we continue the community-wide rigorous modern space weather model validation efforts carried out within GEM, CEDAR and SHINE programs. In this particular effort, in coordination among the Community Coordinated Modeling Center (CCMC), NOAA Space Weather Prediction Center (SWPC), modelers, and science community, we focus on studying the models' capability to reproduce observed ground magnetic field fluctuations, which are closely related to geomagnetically induced current phenomenon. One of the primary motivations of the work is to support NOAA SWPC in their selection of the next numerical model that will be transitioned into operations. Six geomagnetic events and 12 geomagnetic observatories were selected for validation.While modeled and observed magnetic field time series are available for all 12 stations, the primary metrics analysis is based on six stations that were selected to represent the high-latitude and mid-latitude locations. Events-based analysis and the corresponding contingency tables were built for each event and each station. The elements in the contingency table were then used to calculate Probability of Detection (POD), Probability of False Detection (POFD) and Heidke Skill Score (HSS) for rigorous quantification of the models' performance. In this paper the summary results of the metrics analyses are reported in terms of POD, POFD and HSS. More detailed analyses can be carried out using the event by event contingency tables provided as an online appendix. An online interface built at CCMC and described in the supporting information is also available for more detailed time series analyses.

MAGNETIC↗

Community-Wide Validation of Geospace Model Local K-Index Predictions to Support Model Transition to Operations

We present the latest result of a community-wide space weather model validation effort coordinated among the Community Coordinated Modeling Center (CCMC), NOAA Space Weather Prediction Center (SWPC), model developers, and the broader science community. Validation of geospace models is a critical activity for both building confidence in the science results produced by the models and in assessing the suitability of the models for transition to operations. Indeed, a primary motivation of this work is supporting NOAA/SWPCs effort to select a model or models to be transitioned into operations. Our validation efforts focus on the ability of the models to reproduce a regional index of geomagnetic disturbance, the local K-index. Our analysis includes six events representing a range of geomagnetic activity conditions and six geomagnetic observatories representing midlatitude and high-latitude locations. Contingency tables, skill scores, and distribution metrics are used for the quantitative analysis of model performance. We consider model performance on an event-by-event basis, aggregated over events, at specific station locations, and separated into high-latitude and midlatitude domains. A summary of results is presented in this report, and an online tool for detailed analysis is available at the CCMC.

Glocer, A.↗

Solar Wind Fluctuations and Their Consequences on the Magnetosphere

Efforts have been made to extract the physical meaning of each term in our prediction model of the Dst index using the solar wind as the only input. The work has been published Journal of Geophysical Research (Temerin and Li, 21002). We found different terms in the model representing different current in the magnetospheric system and each current has different rise and decay times, with the symmetric ring current the slowest, then the partial ring current, then the tail current. We also have been trying to understand the physical meaning of the diffusion coefficient used in our prediction model of relativistic electron fluxes at geostationary orbit. The model reproduced the observations of MeV electron flux variations well, the diffusion coefficient had be assumed only die to local magnetic field fluctuations, leading to its 10th power dependence on the L. We have studied the theoretical derivation of the diffusion coefficient and we believe that the effect electric field fluctuations at smaller L could become more significant. We have expanded our previous radiation belt electron prediction model, which predicted MeV electron geosynchronous orbit based on solar wind measurements, to predict MeV electrons inside geosynchronous orbit. The model results are compared with measurements from Polar/CEPPAD. Prediction efficiencies of 0.56 and 0.54, respectively, at L=6 and L=4, have been achieved over the entire year of 1998. This work wa reported at 2003 Fall AGU and has been accepted for publication in Space Weather (Barker et al., 2005). We also have used simultaneous measurements of the upstream solar wind and of energetic electrons at geosynchronous orbit to analyze the response of electrons over a very wide energy range, 50 keV-6MeV, to solar wind variations. Enhancements of energetic electron fluxes over this whole energy range are modulated by the solar wind speed and the polarity of the interplanetary magnetic field (IMF). The solar wind speed seems to be a dominant controlling parameter for electrons of all energy. This work has been published in Space Weather (Li et al., 2005).

Li, Xin-Lin↗

Results of inphase axial-torsional fatigue experiments on 304 stainless steel

A series of axial-torsional, inphase, strain-controlled, low-cycle fatigue tests were performed at room temperature on tubular specimens of 304 stainless steel. The program was conducted in cooperation with the task group on multiaxial fatigue research of ASTM committee E-09. The objective was to quantify the variability in multiaxial test results among several laboratories. Only included is data which was generated at the NASA Lewis Research Center's High Temperature Fatigue and Structures Laboratory. The experimental equipment and procedures used are described. The tubular specimens were polished on the outer surface to aid in the use of a cellulose film surface replication technique for crack detection. However, cracking initiated predominantly on the internal surface for all specimens. Honing of the bore of the tubular specimens lessened but did not entirely eliminate this problem. The observed fatigue lives are compared with lives calculated from three multiaxial life models. Constants for the life prediction models were obtained from uniaxial and torsional tests performed on the same heat of material. The observed fatigue lives agreed with calculated lives to within a factor of two for all but one of the life prediction models.

Bonacuse, Peter J.↗

A model and predictive scale of passenger ride discomfort

A model to define the interrelationship of the various factors (vibratory and nonvibratory) important to passenger comfort, in realistic transport vehicle vibration environments was developed. The model represents: (1) a framework for the investigation of comfort within diverse transportation vehicles; (2) a mechanism for the development of a scale of comfort; (3) a mechanism through which design criteria can be obtained for improving the rideability of current and future transportation vehicles; and (4) a tool for obtaining information for the maximization of passenger ride quality, based upon sociological and psychological information. The application of the model is based upon the computational steps necessary for derivation of the comfort scale. The emphasis within the scale is upon the summation of comfort units; the summation being obtained through the use of appropriately determined factors, both within and between axes.

Dempsey, T. K.↗

The use of models to predict potential contamination aboard orbital vehicles

A model of fungal growth on air-exposed, nonnutritive solid surfaces, developed for utilization aboard orbital vehicles is presented. A unique feature of this testable model is that the development of a fungal mycelium can facilitate its own growth by condensation of water vapor from its environment directly onto fungal hyphae. The fungal growth rate is limited by the rate of supply of volatile nutrients and fungal biomass is limited by either the supply of nonvolatile nutrients or by metabolic loss processes. The model discussed is structurally simple, but its dynamics can be quite complex. Biofilm accumulation can vary from a simple linear increase to sustained exponential growth, depending on the values of the environmental variable and model parameters. The results of the model are consistent with data from aquatic biofilm studies, insofar as the two types of systems are comparable. It is shown that the model presented is experimentally testable and provides a platform for the interpretation of observational data that may be directly relevant to the question of growth of organisms aboard the proposed Space Station.

Boraas, Martin E.↗

Hindlimb unloading of growing rats: a model for predicting skeletal changes during space flight

A model that uses hindlimb unloading of rats was developed to study the consequences of skeletal unloading and reloading as occurs during and following space flight. Studies using the model were initiated two decades ago and further developed at National Aeronautics and Space Administration (NASA)-Ames Research Center. The model mimics some aspects of exposure to microgravity by removing weightbearing loads from the hindquarters and producing a cephalic fluid shift. Unlike space flight, the forelimbs remain loaded in the model, providing a useful internal control to distinguish between the local and systemic effects of hindlimb unloading. Rats that are hindlimb unloaded by tail traction gain weight at the same rate as pairfed controls, and glucocorticoid levels are not different from controls, suggesting that systemic stress is minimal. Unloaded bones display reductions in cancellous osteoblast number, cancellous mineral apposition rate, trabecular bone volume, cortical periosteal mineralization rate, total bone mass, calcium content, and maturation of bone mineral relative to controls. Subsequent studies reveal that these changes also occur in rats exposed to space flight. In hindlimb unloaded rats, bone formation rates and masses of unloaded bones decline relative to controls, while loaded bones do not change despite a transient reduction in serum 1,25-dihydroxyvitamin D (1,25D) concentrations. Studies using the model to evaluate potential countermeasures show that 1,25D, growth hormone, dietary calcium, alendronate, and muscle stimulation modify, but do not completely correct, the suppression of bone growth caused by unloading, whereas continuous infusion of transforming growth factor-beta2 or insulin-like growth factor-1 appears to protect against some of the bone changes caused by unloading. These results emphasize the importance of local as opposed to systemic factors in the skeletal response to unloading, and reveal the pivotal role that osteoblasts play in the response to gravitational loading. The hindlimb unloading model provides a unique opportunity to evaluate in detail the physiological and cellular mechanisms of the skeletal response to weightbearing loads, and has proven to be an effective model for space flight.

Non-NASA Center↗

Comparison of structurally diverse simulation models for prediction of epidemic outcomes caused by a long-distance dispersed pathogen

Long-distance dispersal (LDD) pathogens pose substantial challenges for epidemic control due to their ability to generate new infection foci at great distances. While various modeling approaches have been developed to understand and manage such outbreaks, little work has compared how models of different structures behave under shared conditions. Here, in this study, we compare four structurally distinct epidemiological models — EPIMUL, GEMF, PoPS, and Warwick — each adapted to simulate the spread of wheat stripe rust (WSR), a wind-dispersed LDD pathogen, under identical epidemiological parameters and dispersal kernel. Using data from a controlled field experiment, we evaluate the ability of each model to replicate disease prevalence under nine intervention scenarios that vary in timing and culling area. While the models differ substantially in design — ranging from spatial grid-based to network-based and raster-based frameworks — the shared dispersal kernel allowed for close alignment in their predictions. All models accurately captured general epidemic trends, particularly the strong effect of early intervention on disease suppression. We qualitatively compared their behavioral responses across scenarios and also evaluated an ensemble prediction by averaging across model outputs. Our findings highlight how integrating shared epidemiological components into distinct modeling frameworks can improve consistency and accuracy, while reinforcing the importance of early culling in managing LDD pathogen outbreaks.

Dispersal kernel↗

Audibility of Multiple, Low-Frequency Tonal Signals in Noise

The main purpose of this study is to examine the audibility of multiple, low-frequency tones that are placed in distinct auditory channels. Three experiments are described, the goals of which are to determine if the presence of sound in multiple channels results in enhanced audibility and to assess the applicability of the Statistical Summation Model (SSM) to this frequency range. This model predicts that for the case of multiple signals that are in separate auditory channels, implying statistical independence, each with sensitivity value d prime of i, the resulting total sensitivity is given by the square root of the sum of the squares of the individual d prime of i values. In common with previous studies conducted at higher frequencies, the signals are pure tones and the maskers are broadband noise. The requirement that low frequency tones be placed in separate auditory filters limited the number of tones to a maximum of three. The first of the three experiments measured the change in masked thresholds for two- and three-tone signals relative to the level of the equally-detectable single tones. The multiple tone signals were composed of combinations of 55, 120 and 200 Hz tones. The measured changes in thresholds exceeded those predicted by the SSM, although they did not differ statistically from the model predictions. The second experiment employed the same overall approach but acquired more data and concentrated on the three-tone signal. Once again, the measured changes in masked threshold exceeded the model predictions, this time to a statistically-significant degree. Two issues were postulated with the potential to yield inflated changes in masked threshold: interaction between tones resulting in perceptible intermodulation/difference tones, and the assumption that the tones were in distinct auditory filters and statistically independent of one another. The third experiment used two sets of three-tone signals to address these latter concerns. The first set of three tones was composed of harmonically related tone frequencies of 55, 110 and 165 Hz, which was an attempt to reduce effects of intermodulation difference tones. The second set of three tones was chosen to be 110, 220 and 330 Hz, again reducing effects of difference tones, but also providing greater separation between tones. Results for the first set of three tones compared to those of the earlier experiments indicated that intermodulation was not an important effect. The second set of three tones (110, 220, 330 Hz) yielded changes in masked thresholds that, on average, were in good agreement with the SSM, although intersubject variability was large and prohibited a definitive conclusion regarding the concern that tone spacing was inadequate. The results of the three experiments showed that the masked threshold of sounds with multiple (two or three) equally-detectable low frequency tones was lower than those of the single tones. In other words, it is clear that audibility is enhanced by the presence of signals in multiple auditory filters. This finding is consistent with most previous research conducted at higher frequencies. In contrast with previous research, test subjects were, on average, able to detect multitone sounds at lower levels than those predicted using the SSM. Analyses that included Monte Carlo simulations showed that normally distributed errors in the single tone thresholds result in biased estimates of the thresholds of multitone sounds. This phenomenon is likely responsible for at least a substantial fraction of the unexpected deviation of measurements from SSM predictions.

Rafaelof, Menachem↗

Top-down Estimate of Dust Emissions Through Integration of MODIS and MISR Aerosol Retrievals With the Geos-chem Adjoint Model

Predicting the influences of dust on atmospheric composition, climate, and human health requires accurate knowledge of dust emissions, but large uncertainties persist in quantifying mineral sources. This study presents a new method for combined use of satellite-measured radiances and inverse modeling to spatially constrain the amount and location of dust emissions. The technique is illustrated with a case study in May 2008; the dust emissions in Taklimakan and Gobi deserts are spatially optimized using the GEOSChem chemical transport model and its adjoint constrained by aerosol optical depth (AOD) that are derived over the downwind dark-surface region in China from MODIS (Moderate Resolution Imaging Spectroradiometer) reflectance with the aerosol single scattering properties consistent with GEOS-chem. The adjoint inverse modeling yields an overall 51% decrease in prior dust emissions estimated by GEOS-Chem over the Taklimakan-Gobi area, with more significant reductions south of the Gobi Desert. The model simulation with optimized dust emissions shows much better agreement with independent observations from MISR (Multi-angle Imaging SpectroRadiometer) AOD and MODIS Deep Blue AOD over the dust source region and surface PM10 concentrations. The technique of this study can be applied to global multi-sensor remote sensing data for constraining dust emissions at various temporal and spatial scales, and hence improving the quantification of dust effects on climate, air quality, and human health.

MODIS aerosol retrievals↗

Model for Predicting the Performance of Planetary Suit Hip Bearing Designs

Designing a space suit is very complex and often requires difficult trade-offs between performance, cost, mass, and system complexity. During the development period of the suit numerous design iterations need to occur before the hardware meets human performance requirements. Using computer models early in the design phase of hardware development is advantageous, by allowing virtual prototyping to take place. A virtual design environment allows designers to think creatively, exhaust design possibilities, and study design impacts on suit and human performance. A model of the rigid components of the Mark III Technology Demonstrator Suit (planetary-type space suit) and a human manikin were created and tested in a virtual environment. The performance of the Mark III hip bearing model was first developed and evaluated virtually by comparing the differences in mobility performance between the nominal bearing configurations and modified bearing configurations. Suited human performance was then simulated with the model and compared to actual suited human performance data using the same bearing configurations. The Mark III hip bearing model was able to visually represent complex bearing rotations and the theoretical volumetric ranges of motion in three dimensions. The model was also able to predict suited human hip flexion and abduction maximums to within 10% of the actual suited human subject data, except for one modified bearing condition in hip flexion which was off by 24%. Differences between the model predictions and the human subject performance data were attributed to the lack of joint moment limits in the model, human subject fitting issues, and the limited suit experience of some of the subjects. The results demonstrate that modeling space suit rigid segments is a feasible design tool for evaluating and optimizing suited human performance. Keywords: space suit, design, modeling, performance

Cowley, Matthew S.↗

Analysis of Factors Affecting the Performance of RLV Thrust Cell Liners

The reusable launch vehicle (RLV) thrust cell liner, or thrust chamber, is a critical component of the Space Shuttle Main Engine (SSME). It is designed to operate in some of the most severe conditions seen in engineering practice. This requirement, in conjunction with experimentally observed 'dog-house' failure modes characterized by bulging and thinning of the cooling channel wall, provides the motivation to study the factors that influence RLV thrust cell liner performance. Factors or parameters believed to be directly related to the observed characteristic deformation modes leading to failure under in-service loading conditions are identified, and subsequently investigated using the cylindrical version of the higher-order theory for functionally graded materials in conjunction with the Robinson's unified viscoplasticity theory and the power-law creep model for modeling the response of the liner s constituents. Configurations are analyzed in which specific modifications in cooling channel wall thickness or constituent materials are made to determine the influence of these parameters on the deformations resulting in the observed failure modes in the outer walls of the cooling channel. The application of thermal barrier coatings and functional grading are also investigated within this context. Comparison of the higher-order theory results based on the Robinson and power-law creep model predictions has demonstrated that, using the available material parameters, the power-law creep model predicts more precisely the experimentally observed deformation leading to the 'dog-house' failure mode for multiple short cycles, while also providing much improved computational efficiency. However, for a single long cycle, both models predict virtually identical deformations. Increasing the power-law creep model coefficients produces appreciable deformations after just one long cycle that would normally be obtained after multiple cycles, thereby enhancing the efficiency of the analysis. This provides a basis for the development of an accelerated modeling procedure to further characterize dog-house deformation modes in RLV thrust cell liners. Additionally, the results presented herein have demonstrated that the mechanism responsible for deformation leading to 'dog-house' failure modes is driven by pressure, creep/relaxation and geometric effects.

Arnold, Steven M.↗