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At least 685 records · Page 38

Electroencephalogram (EEG) and Magnetoencephalogram (MEG) as Tools for Evaluation of Cognitive Function

We have developed computerized analysis and display techniques to help identify the origins of visually evoked scalped potentials (VESP). The potentials are recorded simultaneously from many electrodes (usually 40 to 48) spaced over the region of the scalp where appreciable evoked potentials are found in response to particular stimulus. Contour mapping algorithms are then used to display the time behavior of equipotential surfaces on the scalp during the VESP. We then use an optimization technique to select the parameters of arrays of current dipole sources within the model until the model equipotential field distribution closely fits the measured data. Computer graphics are then used to display, as a movie, the actual and model scalp potential fields and the parameters of the dipole generators within the model head during the course of VESP activity. We have devised reaction time tests that involve potentially separable stages of cognitive processing and utilize stimuli that produce measurable cognition-related features in the late component of the evoked potential. We have used these techniques to determine the loci in the brain where known cognition-related features in the evoked potential are generated and we have explored the extent to which each of these features can be related to the reaction time tasks. We have also examined the temporal-spatial aspects of their cerebral involvement. Our current work is planned to characterize the age-related changes in the processes performed by such sources. We also use a neuromagnetometer to measure the evoked magnetic fields in similar circumstances; we will discuss the relative merits of the two methodologies.

Fender, Derek H.↗

Ground-Based Passive Microwave Remote Sensing Observations of Soil Moisture at S and L Band with Insight into Measurement Accuracy

Accurate estimates of spatially heterogeneous algorithm variables and parameters are required in determining the spatial distribution of soil moisture using radiometer data from aircraft and satellites. A ground-based experiment in passive microwave remote sensing of soil moisture was conducted in Huntsville, Alabama from July 1-14, 1996 to study retrieval algorithms and their sensitivity to variable and parameter specification. With high temporal frequency observations at S and L band, we were able to observe large scale moisture changes following irrigation and rainfall events, as well as diurnal behavior of surface moisture among three plots, one bare, one covered with short grass and another covered with alfalfa. The L band emitting depth was determined to be on the order of 0-3 or 0-5 cm below 0.30 cubic centimeter/cubic centimeter with an indication of a shallower emitting depth at higher moisture values. Surface moisture behavior was less apparent on the vegetated plots than it was on the bare plot because there was less moisture gradient and because of difficulty in determining vegetation water content and estimating the vegetation b parameter. Discrepancies between remotely sensed and gravimetric, soil moisture estimates on the vegetated plots point to an incomplete understanding of the requirements needed to correct for the effects of vegetation attenuation. Quantifying the uncertainty in moisture estimates is vital if applications are to utilize remotely-sensed soil moisture data. Computations based only on the real part of the complex dielectric constant and/or an alternative dielectric mixing model contribute a relatively insignificant amount of uncertainty to estimates of soil moisture. Rather, the retrieval algorithm is much more sensitive to soil properties, surface roughness and biomass.

Laymon, Charles A.↗

Hemodynamic Responses to Head and Neck Cooling

Personal thermoregulatory systems which provide head and neck cooling are used in the industrial and aerospace environments to alleviate thermal stress. However, little information is available regarding the physiologic and circulatory changes produced by routine operation of these systems. The objective of this study was to measure the scalp temperature and circulatory responses during use of one commercially available thermal control system. The Life Support Systems, Inc. Mark VII portable cooling system and a liquid cooling helmet were used in this study. Two EEG electrodes and one skin temperature transducer were placed on the anterior midline of the scalp to measure the scalp blood and temperature. Blood flow was measured using a bipolar impedance rheograph. Ten subjects, seated in an upright position at normal room temperature, were tested at high, medium, moderate, moderate-low and low coolant temperatures. Scalp blood flow was recorded continuously using a computer data acquisition system with a sampling frequency of 200 Hz. Scalp temperature and cooling helmet Inlet temperature was logged periodically during the test period. This study quantifies the effect of head cooling upon scalp temperature and blood flow. These data may also be used to select operational specifications of the head cooling system for biomedical applications such as the treatment of migraine headaches, scalp cooling during chemotherapy, and cooling of multiple sclerosis patients.

Ku, Yu-Tsuan E.↗

Operational Characteristics of Two Commercially Available Personal Cooling Vests

Personal thermoregulatory systems which provide chest cooling are used in the industrial and aerospace environments to alleviate thermal stress. However, little information is available regarding the physiologic and circulatory changes produced by routine operation of these systems. The objectives of this study were to compare the effectiveness of two passive cooling vests, and to measure the body temperature and circulatory changes produced by each cooling vest configuration. A Life Enhancement Technologies, (LET) ice vest garment and a Steele, Inc. vest were used to cool the chest region of 11 male subjects (25 to 55 yr) in this study. Calf, forearm and finger blood flows were measured using a tetrapolar impedance rheograph. The subjects, seated in an upright position at normal room temperature (approximately 21 C) were tested for 60 min. with the cooling system operating at its maximum cooling capacity. Blood flows were recorded continuously using a computer data acquisition system with a sampling frequency of 250 Hz. Oral, right and left ear temperatures and cooling system parameters were logged manually every 5 min. Arm, leg, chest and rectal temperatures; heart rate; respiration; and an activity index were recorded continuously on a U.F.I., Inc. Biolog ambulatory monitor. No significant differences were found in either the oral or ear temperature responses to the two vests. However, the rectal and mean skin temperatures at the end of the cooling period were both significantly lower (P less than 0.05), approximately 0.2 and 1.9 C, respectively for the LET vest than for the Steele garment. These data show that different vest configurations may produce different thermal responses in healthy male subjects which should be considered in the use of these cooling garments.

Ku, Yu-Tsuan E.↗

Operational Characteristics of Four Commercially Available Personal Cooling Vests

Personal thermoregulatory systems which provide chest cooling are used in the industrial and aerospace environments to alleviate thermal stress. However, little information is available regarding the physiologic and circulatory changes produced by routine operation of these systems. The objectives of this study were to compare the effectiveness of two passive and two active cooling vests, and to measure the body temperature and circulatory changes produced by each cooling vest configuration. The MicroClimate Systems and the Life Enhancement Tech(LET) lightweight liquid cooling vests, the Steele Vest and LET's Zipper Front Garment were used to cool the chest region of 11 male and 10 female subjects (25 to 55 yr.) in this study. Calf, forearm and finger blood flows were measured using a tetrapolar impedance rheograph. The subjects, seated in an upright position at normal room temperature (approx.21 C), were tested for 60 min. with the cooling system operated at its maximum cooling capacity. Blood flows were recorded continuously using a computer data acquisition system with a sampling frequency of 250 Hz. Oral, right and left ear temperatures and cooling system parameters were logged manually every 5 min. Arm, leg, chest and rectal temperatures; heart rate; respiration; and an activity index were recorded continuously on a URI Inc. Biolog ambulatory monitor. In general, the male and female subjects' rectal and ear temperature responses to cooling were similar for all vest configurations tested. Oral temperatures during the recovery period were significantly (P<0.05) lower than during the control period, approx.0.2 - 0.5 C, for both men and women wearing any of the four different garments. The corresponding car temperatures were significantly (P<0.05) decreased approx.0.2 - 0.3 C by the end of the recovery period. Compared to the control period, no significant differences were found in rectal temperatures during cooling and recovery periods. These results show that all vest configurations elicit a similar thermal response in both male and female subject groups. However, subject population variance was rather large and may have masked differences between the vests. One vest may prove more effective than another for a given individual, and experience is the only means of determining this.

Ku, Yu-Tsuan E.↗

Biomedical Application of Aerospace Personal Cooling Systems

Personal thermoregulatory systems which are used by astronauts to alleviate thermal stress during extravehicular activity have been applied to the therapeutic management of multiple sclerosis. However, little information is available regarding the physiologic and circulatory changes produced by routine operation of these systems. The objectives of this study were to compare the effectiveness of two passive and two active cooling vests and to measure the body temperature and circulatory changes produced by each cooling vest configuration. The MicroClimate Systems and the Life Enhancement Tech(LET) lightweight liquid cooling vests, the Steele Vest and LET's Zipper Front Garment were used to cool the chest region of 10 male and female subjects (25 to 55 yr.) in this study. Calf, forearm and finger blood flows were measured using a tetrapolar impedance rheograph. The subjects, seated in an upright position at normal room temperature (approx.22C), were tested for 60 min. with the cooling system operated at its maximum cooling capacity. Blood flows were recorded continuously using a computer data acquisition system with a sampling frequency of 250 Hz. Oral, right and left ear temperatures and cooling system parameters were logged manually every 5 min. Arm, leg, chest and rectal temperatures; heart rate; respiration; and an activity index were recorded continuously on a U.F.I., Inc. Biolog ambulatory monitor. In general, the male and female subjects' oral and ear temperature responses to cooling were similar for all vest configurations tested. Oral temperatures during the recovery period were significantly (P<0.05) lower than during the control period, approx. 0.2 - 0.5C, for both men and women wearing any of the four different garments. The corresponding ear temperatures were significantly (P<0.05) decreased approx.0.2 - 0.4C by the end of the recovery period. Compared to the control period, no significant differences were found in rectal temperatures during cooling and recovery periods.

Ku, Yu-Tsuan E.↗

Laboratory for Atmospheres: Philosophy, Organization, Major Activities, and 2001 Highlights

How can we improve our ability to predict the weather? How is the Earth's climate changing? What can the atmospheres of other planets teach us about our own? The Laboratory for Atmospheres is helping to answer these and other scientific questions. The Laboratory conducts a broad theoretical and experimental research program studying all aspects of the atmospheres of the Earth and other planets, including their structural, dynamical, radiative, and chemical properties. Vigorous research is central to NASA's exploration of the frontiers of knowledge. NASA scientists play a key role in conceiving new space missions, providing mission requirements., and carrying out research to explore the behavior of planetary systems, including, notably, the Earth's. Our Laboratory's scientists also supply outside scientists with technical assistance and scientific data to further investigations not immediately addressed by NASA itself. The Laboratory for Atmospheres is a vital participant in NASA's research program. The Laboratory is part of the Earth Sciences Directorate based at NASA's Goddard Space Flight Center in Greenbelt, Maryland. The Directorate itself comprises the Global Change Data Center; the Earth and Space Data Computing Division; three laboratories: the Laboratory for Atmospheres, the Laboratory for Terrestrial Physics, and the Laboratory for Hydrospheric Processes; and the Goddard Institute for Space Studies (GISS) in New York, New York. In this report, you will find a statement of our philosophy and a description of our role in NASA's mission. You'll also find a broad description of our research and a summary of our scientists' major accomplishments in 2001. The report also presents useful information on human resources, scientific interactions, and outreach activities with the outside community. For your convenience, we have published a version of this report on the Internet. Our Web site includes links to additional information about the Laboratory's Offices and Branches. You can find us on the World Wide Web at http://atmospheres.gsfc.nasa.gov.

Hoegy, Walter R.↗

Bangui Anomaly

Bangui anomaly is the name given to one of the Earth s largest crustal magnetic anomalies and the largest over the African continent. It covers two-thirds of the Central African Republic and therefore the name derives from the capitol city-Bangui that is also near the center of this feature. From surface magnetic survey data Godivier and Le Donche (1962) were the first to describe this anomaly. Subsequently high-altitude world magnetic surveying by the U.S. Naval Oceanographic Office (Project Magnet) recorded a greater than 1000 nT dipolar, peak-to-trough anomaly with the major portion being negative (figure 1). Satellite observations (Cosmos 49) were first reported in 1964, these revealed a 40nT anomaly at 350 km altitude. Subsequently the higher altitude (417-499km) POGO (Polar Orbiting Geomagnetic Observatory) satellite data recorded peak-to-trough anomalies of 20 nT these data were added to Cosmos 49 measurements by Regan et al. (1975) for a regional satellite altitude map. In October 1979, with the launch of Magsat, a satellite designed to measure crustal magnetic anomalies, a more uniform satellite altitude magnetic map was obtained. These data, computed at 375 km altitude recorded a -22 nT anomaly (figure 2). This elliptically shaped anomaly is approximately 760 by 1000 km and is centered at 6%, 18%. The Bangui anomaly is composed of three segments; there are two positive anomalies lobes north and south of a large central negative field. This displays the classic pattern of a magnetic anomalous body being magnetized by induction in a zero inclination field. This is not surprising since the magnetic equator passes near the center of this body.

Taylor, Patrick T.↗

Initial Results of an MDO Method Evaluation Study

The NASA Langley MDO method evaluation study seeks to arrive at a set of guidelines for using promising MDO methods by accumulating and analyzing computational data for such methods. The data are collected by conducting a series of re- producible experiments. In the first phase of the study, three MDO methods were implemented in the SIGHT: framework and used to solve a set of ten relatively simple problems. In this paper, we comment on the general considerations for conducting method evaluation studies and report some initial results obtained to date. In particular, although the results are not conclusive because of the small initial test set, other formulations, optimality conditions, and sensitivity of solutions to various perturbations. Optimization algorithms are used to solve a particular MDO formulation. It is then appropriate to speak of local convergence rates and of global convergence properties of an optimization algorithm applied to a specific formulation. An analogous distinction exists in the field of partial differential equations. On the one hand, equations are analyzed in terms of regularity, well-posedness, and the existence and unique- ness of solutions. On the other, one considers numerous algorithms for solving differential equations. The area of MDO methods studies MDO formulations combined with optimization algorithms, although at times the distinction is blurred. It is important to

Alexandrov, Natalia M.↗

[Genotoxic modification of nucleic acid bases and biological consequences of it. Review and prospects of experimental and computational investigations]

The review is presented of experimental and computational data on the influence of genotoxic modification of bases (deamination, alkylation, oxidation) on the structure and biological functioning of nucleic acids. Pathways are discussed for the influence of modification on coding properties of bases, on possible errors of nucleic acid biosynthesis, and on configurations of nucleotide mispairs. The atomic structure of nucleic acid fragments with modified bases and the role of base damages in mutagenesis and carcinogenesis are considered.

Non-NASA Center↗

In-Flight Assessment of a Pursuit Guidance Display Format for Manually Flown Precision Instrument Approaches

In-flight evaluations of a pursuit guidance display system for manually flown precision instrument approaches were performed. The guidance system was integrated into the RASCAL JUH-60A Black Hawk helicopter. The applicability of the pursuit guidance disp1aFs to the operation of Runway Independent Aircraft (RIA) is made evident because the displays allow the pilot to fly a complex, multi-segment, descending, decelerating approach trajectory. The complex trajectory chosen for this in-flight assessment began from a downwind abeam position at 110 knots and was hand-flown to a 50 ft decision altitude at 40 knots using a rate-command/attitude-hold plus turn-coordination control system. The elements of the pursuit guidance format displayed on a 10-inch liquid crystal display (LCD) flat panel consisted of a flightpath vector and a "leader" aircraft as the pursuit guidance element. Approach guidance was based primarily on carrier-phase differential Global Positioning System (GPS) navigation, and secondarily on both medium accuracy inertial navigation unit states and air data computer states. Required Navigation Performance (RNP) concepts were applied to the construction of display elements such as lateral/vertical deviation indicators and a tunnel that indicated to the pilot, in real-time, the performance with respect to RNP error bounds. The results of the flight evaluations of the guidance display show that precise path control for operating within tight RNP boundaries (RNP 0.007NM/24ft for initial approach, RNP 0.008NM/19ft for intermediate approach, and RNP 0.002NM/9ft for final approach) is attainable with minimal to moderate pilot workload.

Moralez, Ernesto, III↗

Unified Planetary Coordinates System: A Searchable Database of Geodetic Information

Over the past 40 years, an enormous quantity of orbital remote sensing data has been collected for Mars from many missions and instruments. Unfortunately these datasets currently exist in a wide range of disparate coordinate systems, making it extremely difficult for the scientific community to easily correlate, combine, and compare data from different Mars missions and instruments. As part of our work for the PDS Imaging Node and on behalf of the USGS Astrogeology Team, we are working to solve this problem and to provide the NASA scientific research community with easy access to Mars orbital data in a unified, consistent coordinate system along with a wide variety of other key geometric variables. The Unified Planetary Coordinates (UPC) system is comprised of two main elements: (1) a database containing Mars orbital remote sensing data computed using a uniform coordinate system, and (2) a process by which continual maintainance and updates to the contents of the database are performed.

Becker, K. J.a↗

Boundary Layer Transition Results From STS-114

The tool for predicting the onset of boundary layer transition from damage to and/or repair of the thermal protection system developed in support of Shuttle Return to Flight is compared to the STS-114 flight results. The Boundary Layer Transition (BLT) Tool is part of a suite of tools that analyze the aerothermodynamic environment of the local thermal protection system to allow informed disposition of damage for making recommendations to fly as is or to repair. Using mission specific trajectory information and details of each damage site or repair, the expected time of transition onset is predicted to help determine the proper aerothermodynamic environment to use in the subsequent thermal and stress analysis of the local structure. The boundary layer transition criteria utilized for the tool was developed from ground-based measurements to account for the effect of both protuberances and cavities and has been calibrated against flight data. Computed local boundary layer edge conditions provided the means to correlate the experimental results and then to extrapolate to flight. During STS-114, the BLT Tool was utilized and was part of the decision making process to perform an extravehicular activity to remove the large gap fillers. The role of the BLT Tool during this mission, along with the supporting information that was acquired for the on-orbit analysis, is reviewed. Once the large gap fillers were removed, all remaining damage sites were cleared for reentry as is. Post-flight analysis of the transition onset time revealed excellent agreement with BLT Tool predictions.

Berry, Scott A.↗

Overview of Boundary Layer Transition Research in Support of Orbiter Return To Flight

A predictive tool for estimating the onset of boundary layer transition resulting from damage to and/or repair of the thermal protection system was developed in support of Shuttle Return to Flight. The boundary layer transition tool is part of a suite of tools that analyze the aerothermodynamic environment to the local thermal protection system to allow informed disposition of damage for making recommendations to fly as is or to repair. Using mission specific trajectory information and details of each damage site or repair, the expected time (and thus Mach number) at transition onset is predicted to help define the aerothermodynamic environment to use in the subsequent thermal and stress analysis of the local thermal protection system and structure. The boundary layer transition criteria utilized for the tool was developed from ground-based measurements to account for the effect of both protuberances and cavities and has been calibrated against select flight data. Computed local boundary layer edge conditions were used to correlate the results, specifically the momentum thickness Reynolds number over the edge Mach number and the boundary layer thickness. For the initial Return to Flight mission, STS-114, empirical curve coefficients of 27, 100, and 900 were selected to predict transition onset for protuberances based on height, and cavities based on depth and length, respectively.

Berry, Scott A.↗

NASA Tech Briefs, March 2007

Topics include: Advanced Systems for Monitoring Underwater Sounds; Wireless Data-Acquisition System for Testing Rocket Engines; Processing Raw HST Data With Up-to-Date Calibration Data; Mobile Collection and Automated Interpretation of EEG Data; System for Secure Integration of Aviation Data; Servomotor and Controller Having Large Dynamic Range; Digital Multicasting of Multiple Audio Streams; Translator for Optimizing Fluid-Handling Components; AIRSAR Web-Based Data Processing; Pattern Matcher for Trees Constructed From Lists; Reducing a Knowledge-Base Search Space When Data Are Missing; Ground-Based Correction of Remote-Sensing Spectral Imagery; State-Chart Autocoder; Pointing History Engine for the Spitzer Space Telescope; Low-Friction, High-Stiffness Joint for Uniaxial Load Cell; Magnet-Based System for Docking of Miniature Spacecraft; Electromechanically Actuated Valve for Controlling Flow Rate; Plumbing Fixture for a Microfluidic Cartridge; Camera Mount for a Head-Up Display; Core-Cutoff Tool; Recirculation of Laser Power in an Atomic Fountain; Simplified Generation of High-Angular-Momentum Light Beams; Imaging Spectrometer on a Chip; Interferometric Quantum-Nondemolition Single-Photon Detectors; Ring-Down Spectroscopy for Characterizing a CW Raman Laser; Complex Type-II Interband Cascade MQW Photodetectors; Single-Point Access to Data Distributed on Many Processors; Estimating Dust and Water Ice Content of the Martian Atmosphere From THEMIS Data; Computing a Stability Spectrum by Use of the HHT; Theoretical Studies of Routes to Synthesis of Tetrahedral N4; Estimation Filter for Alignment of the Spitzer Space Telescope; Antenna for Measuring Electric Fields Within the Inner Heliosphere; Improved High-Voltage Gas Isolator for Ion Thruster; and Hybrid Mobile Communication Networks for Planetary Exploration.

Source record↗

Summary of the Synergistic Effects Obtained by the Present Study of Vortical Flows

This chapter identifies the benefits that occurred to the AVT-113 task group members and the resulting progress made to two separate vortical flow proposals for task group status being combined into one. Both of these proposals dealt with multiple-vortices, and though they shared different focuses, the general topic, as well as the specific features of this flow, made it of great interest to each sub-task or facet member. The joint meetings increased our overall understanding of vortical flow and the synergistic benefits are summarized in terms of experimental and computational data, virtual laboratory usage, dissemination of results, and career development.

Lamar, John E.↗

Transverse Injection into Subsonic Crossflow with Various Injector Orifice Geometries

Computational and experimental results are presented for a case study of single injectors employed in 90 deg transverse injection into a non-reacting subsonic flow. Different injector orifice shapes are used (including circular, square, diamond-shaped, and wide rectangular slot), all with constant cross-sectional area, to observe the effects of this variation on injector penetration and mixing. Whereas the circle, square, and diamond injector produce similar jet plumes, the wide rectangular slot produces a plume with less vertical penetration than the others. There is also some evidence that the diamond injector produces slightly faster penetration with less mixing of the injected fluid. In addition, a variety of rectangular injectors were analyzed, with varying length/width ratios. Both experimental and computational data show improved plume penetration with increased streamwise orifice length. 3-D Reynolds-Averaged Navier-Stokes (RANS) results are obtained for the various injector geometries using NCC (National Combustion Code) with the kappa-epsilon turbulence model in multi-species modes on an unstructured grid. Grid sensitivity results are also presented which indicate consistent qualitative trends in the injector performance comparisons with increasing grid refinement.

Foster, Lancert E.↗

CFD Simulations for the Effect of Unsteady Wakes on the Boundary Layer of a Highly Loaded Low-Pressure Turbine Airfoil (L1A)

This report is the third part of a three-part final report of research performed under an NRA cooperative Agreement contract. The first part was published as NASA/CR-2012-217415. The second part was published as NASA/CR-2012-217416. The study of the very high lift low-pressure turbine airfoil L1A in the presence of unsteady wakes was performed computationally and compared against experimental results. The experiments were conducted in a low speed wind tunnel under high (4.9%) and then low (0.6%) freestream turbulence intensity for Reynolds number equal to 25,000 and 50,000. The experimental and computational data have shown that in cases without wakes, the boundary layer separated without reattachment. The CFD was done with LES and URANS utilizing the finite-volume code ANSYS Fluent (ANSYS, Inc.) under the same freestream turbulence and Reynolds number conditions as the experiment but only at a rod to blade spacing of 1. With wakes, separation was largely suppressed, particularly if the wake passing frequency was sufficiently high. This was validated in the 3D CFD efforts by comparing the experimental results for the pressure coefficients and velocity profiles, which were reasonable for all cases examined. The 2D CFD efforts failed to capture the three dimensionality effects of the wake and thus were less consistent with the experimental data. The effect of the freestream turbulence intensity levels also showed a little more consistency with the experimental data at higher intensities when compared with the low intensity cases. Additional cases with higher wake passing frequencies which were not run experimentally were simulated. The results showed that an initial 25% increase from the experimental wake passing greatly reduced the size of the separation bubble, nearly completely suppressing it.

Vinci, Samuel, J.↗