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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 703 records · Page 39

All sources NASA NTRS DOE OSTI

NASA NTRS2014

Design and Control of Modular Spine-Like Tensegrity Structures

We present a methodology enabled by the NASA Tensegrity Robotics Toolkit (NTRT) for the rapid structural design of tensegrity robots in simulation and an approach for developing control systems using central pattern generators, local impedance controllers, and parameter optimization techniques to determine effective locomotion strategies for the robot. Biomimetic tensegrity structures provide advantageous properties to robotic locomotion and manipulation tasks, such as their adaptability and force distribution properties, flexibility, energy efficiency, and access to extreme terrains. While strides have been made in designing insightful static biotensegrity structures, gaining a clear understanding of how a particular structure can efficiently move has been an open problem. The tools in the NTRT enable the rapid exploration of the dynamics of a given morphology, and the links between structure, controllability, and resulting gait efficiency. To highlight the effectiveness of the NTRT at this exploration of morphology and control, we will provide examples from the designs and locomotion of four different modular spine-like tensegrity robots.

Modular↗

DOE OSTI2017

Structure-guided design, synthesis and evaluation of oxazolidinone-based inhibitors of norovirus 3CL protease

Acute nonbacterial gastroenteritis caused by noroviruses constitutes a global public health concern and a significant economic burden. There are currently no small molecule therapeutics or vaccines for the treatment of norovirus infections. In this work, a structure-guided approach was utilized in the design of a series of inhibitors of norovirus 3CL protease that embody an oxazolidinone ring as a novel design element for attaining optimal binding interactions. Low micromolar cell-permeable inhibitors that display anti-norovirus activity have been identified. The mechanism of action, mode of binding, and structural rearrangements associated with the interaction of the inhibitors and the enzyme were elucidated using X-ray crystallography.

59 BASIC BIOLOGICAL SCIENCES↗

NASA NTRS1992

Design and structural analysis of Mars Rover RTG

The Mars Rover and Sample Return mission's radioisotope thermoelectric generator (RTG) is presently subjected to a structural and mass analysis in view of a reference mission scenario, an illustrative Rover design and Martian activities agenda, and RTG power system requirements and environmental constraints. The modular heat-source stack in the Rover RTG can be held together by axial load springs. The RTGs should be mounted on the Rover with a vertical orientation, in order to avoid the buildup of windborne Martian sand on its heat-rejection surfaces.

Schock, Alfred↗

NASA NTRS1938

Pressure distribution over an NACA 23012 airfoil with a slotted and a plain flap

Report presents the results of pressure-distribution of an NACA 23012 airfoil equipped with a slotted flap and with a plain flap conducted in the 7 by 10-foot wind tunnel. A test installation was used in which the 7-foot-span airfoil was mounted vertically between the upper and lower sides of the closed test section so that two-dimensional flow was approximated. The pressures were measured on the upper and lower surfaces at one chord section both on the main airfoil and on the flaps for several different flap deflections and at several angles of attack. The data are presented in the form of pressure-distribution diagrams and as graphs of calculated section coefficients for the airfoil-and-flap combinations and also for the flaps alone. The results are useful for application to rib and flap structural design; in addition, the plain-flap data furnish considerable information applicable to the structural design of plain ailerons.

Wenzinger, Carl J↗

NASA NTRS1972

Design considerations for fiber composite structures

An overview of the design methodology for designing structural components from fiber composites is presented. In particular, the need for new conceptual structural designs for the future is discussed and the evolution of conceptual design is illustrated. Sources of design data, analysis and design procedures, and the basic components of structural fiber composites are cited and described. Examples of tradeoff studies and optimum designs are discussed and a simple structure is described in some detail.

Chamis, C. C.↗

NASA NTRS1979

Advanced composite vertical stabilizer for DC-10 transport aircraft

Structural design, tooling, fabrication, and test activities are reported for a program to develop an advanced composite vertical stabilizer (CVS) for the DC 10 Commercial Transport Aircraft. Structural design details are described and the status of structural and weight analyses are reported. A structural weight reduction of 21.7% is currently predicted. Test results are discussed for sine wave stiffened shear webs containing representative of the CVS spar webs and for lightning current transfer and tests on a panel representative of the CVS skins.

Stephens, C. O.↗

NASA NTRS1993

Validated technology for the reduction of spacecraft vibrations - Controls-Structures Integration (CSI)

The NASA Langley Research Center has constructed several testbeds to assess the viability of flexible structure control. It is found, however, that simply adding sensors, actuators, and a control system to an existing structure (i.e. space platform) is not the preferred methodology for improving pointing performance. When the structure is designed without regard to pointing control, significant design freedom is lost. The preferred design procedure is to simultaneously design the structure and the control system, hence, the name Controls-Structures Integration. By designing the structure and control system simultaneously, much higher efficiency can be achieved. In this study, an 18 m long truss structure with several appendages was enhanced through integrated controls and structures design. The design was fabricated and tested for validation of the methodology. Test results collaborated predictions and showed a 60 percent reduction in control energy for the enhanced test article.

Newsom, Jerry R.↗

NASA NTRS1972

Design considerations for fiber composite structures.

An overview of the design methodology for designing structural components from fiber composites is presented. In particular, the need for new conceptual structural designs for the future is discussed and the evolution of conceptual design is illustrated. Sources of design data, analysis and design procedures, and the basic components of structural fiber composites are cited and described. Examples of trade-off studies and optimum designs are discussed, and a simple structure is described in some detail.

Chamis, C. C.↗

DOE OSTI2023

In Situ Wind and Turbulence Measurements in a Field of Full-Size Parabolic Trough Solar Collectors

Concentrated Solar Power (CSP) is a promising method for using Solar power for electricity generation with thermal energy storage. One of the primary drivers of structural design costs of CSP collector structures is wind loading. To date, the design of these structures has relied on data from wind tunnels that do not adequately capture the dynamic effects observed at scale. NREL initiated a field measurement campaign at the operational Nevada Solar One (NSO) powerplant that uses parabolic troughs as solar collectors. The aim of the project is a detailed characterization of prevailing wind and turbulence conditions and resulting operational loads on parabolic troughs, providing insights on structural dynamic response, and generating a first-of-a-kind, comprehensive, high-resolution wind-loading dataset available for validating simulations of wind loading on collector structures. The measurements at NSO consist of Sonic anemometers on masts at different heights to characterize the incoming flow and conditions within and above the trough field, in combination with a Doppler Lidar scanning the horizontal plane above the troughs. The wind measurements at NSO have been continuously operating since October 2021 and provide a year-long dataset characterizing wind and turbulence conditions. The structural load measurements start in November 2022 and will complement the wind measurements. In this poster, we present first results of the wind measurement campaign by highlighting days with different atmospheric flow conditions. We identified three main factors altering the flow over the parabolic troughs: Wind speed, wind direction, and the angle of the parabolic troughs. The highest loads are expected when the wind blows perpendicular to the trough rows. In this case, the first rows experience the highest loads and block the subsequent rows, creating conditions with decreased wind speed and enhanced turbulence within the trough field. Also, turbulent length scales change. These affected conditions produce unique load cases on the structures that will be captured by the load measurements. If the wind blows along the trough rows, wind and turbulence conditions are less influenced by the troughs.

atmospheric turbulence↗

DOE OSTI2023

In Situ Wind and Turbulence Measurements in a Field of Full-Size Parabolic Trough Collectors

concentrated solar power↗

DOE OSTI2011

Structure-guided Design and Immunological Characterization of Immunogens Presenting the HIV-1 gp120 V3 Loop on a CTB Scaffold

V3 loop is a major neutralizing determinant of the HIV-1 gp120. Using 3D structures of cholera toxin B subunit (CTB), complete V3 in the gp120 context, and V3 bound to a monoclonal antibody (mAb), we designed two V3-scaffold immunogen constructs (V3-CTB). The full-length V3-CTB presenting the complete V3 in a structural context mimicking gp120 was recognized by the large majority of our panel of 24 mAbs. The short V3-CTB presenting a V3 fragment in the conformation observed in the complex with the 447-52D Fab, exhibited high-affinity binding to this mAb. The immunogens were evaluated in rabbits using DNA-prime/protein-boost protocol. Boosting with the full-length V3-CTB induced high anti-V3 titers in sera that potently neutralize multiple HIV virus strains. The short V3-CTB was ineffective. The results suggest that very narrow antigenic profile of an immunogen is associated with poor Ab response. An immunogen with broader antigenic activity elicits robust Ab response.

59 BASIC BIOLOGICAL SCIENCES↗

NASA NTRS1991

Optimization techniques applied to passive measures for in-orbit spacecraft survivability

Spacecraft designers have always been concerned about the effects of meteoroid impacts on mission safety. The engineering solution to this problem has generally been to erect a bumper or shield placed outboard from the spacecraft wall to disrupt/deflect the incoming projectiles. Spacecraft designers have a number of tools at their disposal to aid in the design process. These include hypervelocity impact testing, analytic impact predictors, and hydrodynamic codes. Analytic impact predictors generally provide the best quick-look estimate of design tradeoffs. The most complete way to determine the characteristics of an analytic impact predictor is through optimization of the protective structures design problem formulated with the predictor of interest. Space Station Freedom protective structures design insight is provided through the coupling of design/material requirements, hypervelocity impact phenomenology, meteoroid and space debris environment sensitivities, optimization techniques and operations research strategies, and mission scenarios. Major results are presented.

Mog, Robert A.↗

DOE OSTI2016

Structure-based design of broadly protective group a streptococcal M protein-based vaccines

Here, a major obstacle to the development of broadly protective M protein-based group A streptococcal (GAS) vaccines is the variability within the N-terminal epitopes that evoke potent bactericidal antibodies. The concept of M type-specific protective immune responses has recently been challenged based on the observation that multivalent M protein vaccines elicited cross-reactive bactericidal antibodies against a number of non-vaccine M types of GAS. Additionally, a new “cluster-based” typing system of 175 M proteins identified a limited number of clusters containing closely related M proteins. In the current study, we used the emm cluster typing system, in combination with computational structure-based peptide modeling, as a novel approach to the design of potentially broadly protective M protein-based vaccines.

59 BASIC BIOLOGICAL SCIENCES↗

NASA NTRS1976

Approximation concepts for efficient structural synthesis

It is shown that efficient structural synthesis capabilities can be created by using approximation concepts to mesh finite element structural analysis methods with nonlinear mathematical programming techniques. The history of the application of mathematical programming techniques to structural design optimization problems is reviewed. Several rather general approximation concepts are described along with the technical foundations of the ACCESS 1 computer program, which implements several approximation concepts. A substantial collection of structural design problems involving truss and idealized wing structures is presented. It is concluded that since the basic ideas employed in creating the ACCESS 1 program are rather general, its successful development supports the contention that the introduction of approximation concepts will lead to the emergence of a new generation of practical and efficient, large scale, structural synthesis capabilities in which finite element analysis methods and mathematical programming algorithms will play a central role.

Schmit, L. A., Jr.↗

NASA NTRS1979

Weight optimization of ultra large space structures

The paper describes the optimization of a solar power satellite structure for minimum mass and system cost. The solar power satellite is an ultra large low frequency and lightly damped space structure; derivation of its structural design requirements required accommodation of gravity gradient torques which impose primary loads, life up to 100 years in the rigorous geosynchronous orbit radiation environment, and prevention of continuous wave motion in a solar array blanket suspended from a huge, lightly damped structure subject to periodic excitations. The satellite structural design required a parametric study of structural configurations and consideration of the fabrication and assembly techniques, which resulted in a final structure which met all requirements at a structural mass fraction of 10%.

Reinert, R. P.↗

DOE OSTI2022

Structure-based design of prefusion-stabilized human metapneumovirus fusion proteins

The human metapneumovirus (hMPV) fusion (F) protein is essential for viral entry and is a key target of neutralizing antibodies and vaccine development. The prefusion conformation is thought to be the optimal vaccine antigen, but previously described prefusion F proteins expressed poorly and were not well stabilized. Here, we use structures of hMPV F to guide the design of 42 variants containing stabilizing substitutions. Through combinatorial addition of disulfide bonds, cavity-filling substitutions, and improved electrostatic interactions, we describe a prefusion-stabilized F protein (DS-CavEs2) that expresses at 15mg/L and has a melting temperature of 71.9°C. Crystal structures of two prefusion-stabilized hMPV F variants reveal that antigenic surfaces are largely unperturbed. Importantly, immunization of mice with DS-CavEs2 elicits significantly higher neutralizing antibody titers against hMPV A1 and B1 viruses than postfusion F. The improved properties of DS-CavEs2 will advance the development of hMPV vaccines and the isolation of therapeutic antibodies.

59 BASIC BIOLOGICAL SCIENCES↗

NASA NTRS2013

Conceptual Design and Structural Analysis of an Open Rotor Hybrid Wing Body Aircraft

Through a recent NASA contract, Boeing Research and Technology in Huntington Beach, CA developed and optimized a conceptual design of an open rotor hybrid wing body aircraft (HWB). Open rotor engines offer a significant potential for fuel burn savings over turbofan engines, while the HWB configuration potentially allows to offset noise penalties through possible engine shielding. Researchers at NASA Langley converted the Boeing design to a FLOPS model which will be used to develop take-off and landing trajectories for community noise analyses. The FLOPS model was calibrated using Boeing data and shows good agreement with the original Boeing design. To complement Boeing s detailed aerodynamics and propulsion airframe integration work, a newly developed and validated conceptual structural analysis and optimization tool was used for a conceptual loads analysis and structural weights estimate. Structural optimization and weight calculation are based on a Nastran finite element model of the primary HWB structure, featuring centerbody, mid section, outboard wing, and aft body. Results for flight loads, deformations, wing weight, and centerbody weight are presented and compared to Boeing and FLOPS analyses.

Gern, Frank H.↗

NASA NTRS1996

Minimum Weight Design of a Generic Axisymmetric Inlet

A new minimum weight design method for high-speed axisymmetric inlets was demonstrated on a generic inlet. The method uses Classical Beam Theory and shell buckling to determine the minimum required equivalent isotropic thickness for a stiffened shell based on prescribed structural design requirements and load conditions. The optimum spacing and equivalent isotropic thickness of ring frame supports are computed to prevent buckling. The method thus develops a preliminary structural design for the inlet and computes the structural weight. Finite element analyses were performed on the resulting inlet design to evaluate the analytical results. Comparisons between the analytical and finite element stresses and deflections identified areas needing improvement in the analytical method. The addition of the deflection due to shear and a torsional buckling failure mode to the new method brought its results in line with those from the finite element analyses. Final validation of the new method will be made using data from actual inlets.

Nadell, Shari-Beth↗