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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 73 records · Page 4

Hypernetwork Science: From Multidimensional Networks to Computational Topology

As data structures and mathematical objects used for complex systems modeling, hypergraphs sit nicely poised between on the one hand the world of network models, and on the other that of higher-order mathematical abstractions from algebra, lattice theory, and topology. They are able to represent complex systems interactions more faithfully than graphs and networks, while also being some of the simplest classes of systems representing topological structures as collections of multidimensional objects connected in a particular pattern. In this paper we discuss the role of (undirected) hypergraphs in the science of complex networks, and provide a mathematical overview of the core concepts needed for hypernetwork modeling, including duality and the relationship to bicolored graphs, quantitative adjacency and incidence, the nature of walks in hypergraphs, and available topological relationships and properties. We close with a brief discussion of two example applications: biomedical databases for disease analysis, and domain-name system (DNS) analysis of cyber data.

Joslyn, Cliff A.↗

Enhancing gene regulatory network inference through data integration with markov random fields

Here, a gene regulatory network links transcription factors to their target genes and represents a map of transcriptional regulation. Much progress has been made in deciphering gene regulatory networks computationally. However, gene regulatory network inference for most eukaryotic organisms remain challenging. To improve the accuracy of gene regulatory network inference and facilitate candidate selection for experimentation, we developed an algorithm called GRACE (Gene Regulatory network inference ACcuracy Enhancement). GRACE exploits biological a priori and heterogeneous data integration to generate high- confidence network predictions for eukaryotic organisms using Markov Random Fields in a semi-supervised fashion. GRACE uses a novel optimization scheme to integrate regulatory evidence and biological relevance. It is particularly suited for model learning with sparse regulatory gold standard data. We show GRACE’s potential to produce high confidence regulatory networks compared to state of the art approaches using Drosophila melanogaster and Arabidopsis thaliana data. In an A. thaliana developmental gene regulatory network, GRACE recovers cell cycle related regulatory mechanisms and further hypothesizes several novel regulatory links, including a putative control mechanism of vascular structure formation due to modifications in cell proliferation.

59 BASIC BIOLOGICAL SCIENCES↗

Detecting Periodic Subsequences in Cyber Security Data

Anomaly detection for cyber-security defence has garnered much attention in recent years providing an orthogonal approach to traditional signature-based detection systems. Anomaly detection relies on building probability models ofnormal computer network behaviour and detecting deviations from the model. Most data sets used for cyber-security have a mix of user-driven events and automated network events, which most often appears as polling behaviour. Separating these automated events from those caused by human activity is essential to building good statistical models for anomaly detection. In this article, we present a change point detection framework for identifying automated network events appearing as periodic subsequences of event times. The opening event of each subsequence is interpreted as a human action which then generates an automated, periodic process. Difficulties arising from the presence of duplicate and missing data are addressed. The methodology is demonstrated using authentication data from Los Alamos National Laboratory's enterprise computer network.

97 MATHEMATICS AND COMPUTING↗

Computational Analysis of Interactions of the Oral Microbiota

The human oral microbiome is a complex site containing many hundreds of species with the community response of this microbiome having a large effect on human health. The complexity of this site has spoken to the need for applying –omics techniques to better understand which microbial species are present, their contribution to the microbiome and how this may change as a function of disease. The kinds of datasets that emerge from these –omics studies require computational analysis to gain robust results. New research has also been focused on applying these methods to build computational networks and models that better describe the myriad of interactions between microbial species of the oral cavity and how this changes as a result of infection. In this work, I describe the state of the field at this point, what kinds of computational networks have been inferred and what they show. I also describe where the field is heading in the next few years and how more in depth –omics analysis can lead to more detailed models of interactions at this site and improve human health.

-omics↗

A Novel Protection Scheme for Unbalanced Faults in Inverter Dominated Networks: A Computationally Efficient Algorithm for Entry-Level Relays

Microgrids are now a common practice in distribution systems to increase resilience and reliability. However, microgrid protection remains a critical challenge, considering its requirement to operate in both grid connected and islanded, and the variability in fault characteristics under each mode of operation. This paper presents unbalanced power (S unb ) based fault detection algorithm, which considers local voltage and current unbalances to determine faults in the system. S unb is a computationally efficient fault detection algorithm that is suitable for implementation in the programmable logic of entry level protective relays. In addition, the difference in current and voltage unbalance (D n ) is used to determine the fault type. The proposed method demonstrates high sensitivity and selectivity for line-to-ground (LG), line-to-line (LL), and double line-to-ground (LLG) faults, representing the most common faults in distribution systems. It also allows relay coordination with upstream and downstream protection devices in both island and grid connected operation, while preserving grading margins. The same pickup and time multiplier settings of a particular relay for both modes of operation eliminates the need for adaptive settings, which rely on communication networks. Validation was performed with a hardware-in-the-loop (HIL) setup using Typhoon HIL real time simulator interfaced with three entry-level, SEL 751 relays. Results confirmed the algorithm’s ability to discriminate fault conditions, and determine the fault type under both operating modes, maintain fast detection times, and ensure proper protection coordination.

fault classification↗

Technologies for increasing bandwidth in partitioned hierarchical networks

Technologies for increasing the bandwidth of partitioned hierarchical networks is disclosed. If each partition of network groups of a computer network are isolated, then the connections between the network groups of different partitions may go unused. However, careful selection of the network connections between partitions of different network groups may allow for a pseudo-direct connection between two network groups of the same partition using a single non-blocking switch in a network group of a different partition. Such a configuration can increase the effective bandwidth available within a partition without affecting the bandwidth available in another partition.

Flajslik, Mario↗

Toward a Seamless Integration of Computing, Experimental, and Observational Science Facilities: A Blueprint to Accelerate Discovery

The Department of Energy, Office of Science operates world-leading facilities for experimental, observational, and computational science. DOE supercomputing facilities will reach performance at the scale of ExaFLOPs in the coming years, enabling new vistas of scale and precision for large scale simulations and data analysis. Experimental scientific facilities are undergoing similar upgrades that will lead to higher data rates and correspondingly larger computational demands, and will increase the need for near-real-time processing and resilient support for more complex workflows. A transformation of science is underway, with workloads at supercomputing facilities increasingly driven by this explosion of data from instruments and experimental facilities, as well as the accelerating use of Artificial Intelligence (AI) as a tool for scientific discovery. A seamless integration of computing, networking, instruments, and experimental facilities is required to support these emerging workloads and open up a new frontier of U.S. leadership in scientific discovery. We propose to accomplish this by providing frictionless access to the ASCR supercomputing facilities. We describe our vision of combining the power of ASCR supercomputers and networking infrastructure into an integrated scalable fabric, available to end user scientists via interfaces that aim to automate and simplify access to high performance computing systems. This will enable unprecedented computational science capabilities for experimental and observational facilities, and will create new opportunities to combine large simulations and modeling with experimental facility data analysis. This blueprint for creating an integrated network of computational and experimental facilities will provide an enriched discovery environment and open doors for new scientific communities to access the DOE’s world-leading computing and networking capabilities.

97 MATHEMATICS AND COMPUTING↗

Network traffic control for multi-homed end-hosts via SDN

Software-defined networking (SDN) is an emerging technology of efficiently controlling and managing computer networks, such as in data centres, wide-area networks, as well as in ubiquitous communication. In this study, the authors explore the idea of embedding the SDN components, represented by SDN controller and virtual switch, in end-hosts to improve network performance. In particular, the authors consider load balancing across multiple network interfaces on end-hosts with different link capacity scenarios. The authors have explored and implemented different SDN-based load-balancing approaches based on OpenFlow software switches, and have demonstrated the feasibility and the potential of this approach. The proposed system has been evaluated with MultiPath transmission control protocol (MPTCP). Furthermore, the proposed results demonstrated the potential of applying the SDN concepts on multi-homed devices resulting in an increase in achieved throughput of 55% compared to the legacy single network approach and 10% compared to the MPTCP.

97 MATHEMATICS AND COMPUTING↗

Priority-enabled Load Balancing for Dispersed Computing

Opportunistic managed access to local in-network compute resources can improve the performance of distributed applications and reduce the dependence on shared network resources. Instead of backhauling application data to a centralized cloud data center for processing, networked services may be adaptively and continuously dispersed into shared compute resources that are closer to the source of need. While this approach has several benefits, support for mission-aware access to computation is often an afterthought, and is implemented as a brittle extension over traditional load-balancer solutions.In this work, we investigate the design of two priority-aware resource allocation strategies and two load-balancing dispatching strategies as first class citizens in an open-source dispersed computing middleware. We present a control theoretic analysis of these load-balancing primitives to identify weaknesses and strengths in our design, and recommend future directions. In parallel, we prototype two priority-aware allocation algorithms to validate our priority predictions. In initial experiments our prototype shows substantial gains in processing prioritized load. Finally, we make our source-code and experimental configurations open source.

Paulos, Aaron↗

Mota Mapper: A Multi-Objective Topology-Aware Mapper Library

Mota is a library that provides several heuristics for mapping tasks to compute ranks (processes) on a networked computer cluster or supercomputer. It was originally designed for task placement of adaptive mesh refinement codes (AMR). It is multi-objective in the sense that it simultaneously balances (potentially multiple types of) computational load on each rank as well as the communication traffic between the boxes. The heuristics used for mapping include algorithms such as greedy list assignment and space-filling curves, as well as algorithms from graph analysis such as adjacency matrix bandwidth reduction, recursive bisection, and greedy graph placement.

Chan, Cy↗

Modeling behavior in a network using event logs

A framework is provided for modeling the activity surrounding user credentials and/or machine level activity on a computer network using computer event logs by viewing the logs attributed to each user as a multivariate data stream. The methodology performs well in detecting compromised user credentials at a very low false positive rate. Such a methodology may detect both users of compromised credentials by external actors and otherwise authorized users who have begun engaging in malicious activity.

Turcotte, Melissa J. M.↗

Super-resolution and segmentation deep learning for breast cancer histopathology image analysis

Traditionally, a high-performance microscope with a large numerical aperture is required to acquire high-resolution images. However, the images’ size is typically tremendous. Therefore, they are not conveniently managed and transferred across a computer network or stored in a limited computer storage system. As a result, image compression is commonly used to reduce image size resulting in poor image resolution. Here, we demonstrate custom convolution neural networks (CNNs) for both super-resolution image enhancement from low-resolution images and characterization of both cells and nuclei from hematoxylin and eosin (H&E) stained breast cancer histopathological images by using a combination of generator and discriminator networks so-called super-resolution generative adversarial network-based on aggregated residual transformation (SRGAN-ResNeXt) to facilitate cancer diagnosis in low resource settings. The results provide high enhancement in image quality where the peak signal-to-noise ratio and structural similarity of our network results are over 30 dB and 0.93, respectively. The derived performance is superior to the results obtained from both the bicubic interpolation and the well-known SRGAN deep-learning methods. In addition, another custom CNN is used to perform image segmentation from the generated high-resolution breast cancer images derived with our model with an average Intersection over Union of 0.869 and an average dice similarity coefficient of 0.893 for the H&E image segmentation results. Finally, we propose the jointly trained SRGAN-ResNeXt and Inception U-net Models, which applied the weights from the individually trained SRGAN-ResNeXt and inception U-net models as the pre-trained weights for transfer learning. The jointly trained model’s results are progressively improved and promising. We anticipate these custom CNNs can help resolve the inaccessibility of advanced microscopes or whole slide imaging (WSI) systems to acquire high-resolution images from low-performance microscopes located in remote-constraint settings.

60 APPLIED LIFE SCIENCES↗

Cyber Infrastructure for the Smart Electric Grid

As electric power systems undergo a transformative upgrade with the integration of advanced technologies to enable the smarter electric grid, professionals who work in the area require a new understanding of the evolving complexity of the grid. Cyber Infrastructure for the Smart Electric Grid delivers a comprehensive overview of the fundamental principles of smart grid operation and control, smart grid technologies, including sensors, communication networks, computation, data management, and cyber security, and the interdependencies between the component technologies on which a smart grid's security depends. The book offers readers the opportunity to critically analyze the smart grid infrastructure needed to sense, communicate, compute, and control in a secure way.

communication networks↗