Changes in the electrical activity of the hearts of animals under the influence of high oxygen pressure
Heart activity during high pressure oxygen toxicity in dogs and guinea pigs
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Heart activity during high pressure oxygen toxicity in dogs and guinea pigs
Cytoplasmic alterations and fat vacuole formation in pneumocytes of guinea pigs exposed to severe hypoxia in low pressure chamber
Morphological changes of various peripheral nervous system components of rats, rabbits, and guinea pigs under influence of cobalt 60 irradiation
Samples of endolymph and perilymph of between 0.002 and 0.003 milliliter were obtained from single ears of living pigeons. Measurements of specific gravity were made in density gradient column, and it was shown that at the pigeon's body temperature (approximately 40 ° C), the specific gravity (referred to water at 4 ° C) of endolymph is 1.0033 and that of perilymph is 1.0022. Preliminary, measurements indicate that at 40 ° C, the viscosity of endolymph is 1.15 centipoise and the viscosity of perilymph is 0.78 centipoise. The unusual high potassium concentration and low sodium concentration of endolymph reported for the cat and the guinea pig were confirmed for the pigeon.
Energy transfer effects on pathophysiological responses of guinea pigs and bradycardia response in monkeys under minus G impact acceleration
Pathophysiological responses of guinea pigs and monkeys to tailward acting impact accelerations
Hyperventilation effect on blood flow of strial vessels in guinea pigs
Dimethyl sulfoxide /DMSO/ effect on morphology in basal layers of stratum corneum of guinea pig skin after profuse swabbing
Hematological and pathomorphological changes in guinea pigs under simulated ionizing radiation and space flight conditions
Two support and restraint systems for headward, backward, and forward impact accelerations with guinea pig subjects
Histological and histochemical studies of dephosphorylating enzyme distribution in muscle spindle capsule of guinea pig thigh muscles and cat calf muscles
Evidence for maintenance or breakdown of natural or acquired resistance of guinea pigs in simulated spacecraft environment
Sonic boom effects on guinea pigs Corti organ, comparing auditory damage in cochlea with hair cell damage
Cochlear sensory epithelium and Corti organ degeneration after noise exposure in guinea pigs and cats, using scanning electron microscopy
Preflight studies on Aeromonas proteolytica are reported to investigate the possibility of genetic alterations resulting in increased proteolysis in spacecraft environments. This organism may be present on human tissue and could pose medical problems if its endopeptidase and a hemolysin were to be produced in ususually high quantities or altered in such a way as to be more effective in their activities. Considered are: (1) Development of a nutrative holding medium for suspension of organisms; (2) the establishment of baseline information for the standardization of the assay for endopeptidase levels and hemolytic titers; (3) formulation of a method by which intracutaneous hemorrhage could be quantitated in guinea pig tissue; and (4) the responses of these organisms to parameters of spaceflight and experimentation.
Textiles proposed for spacecraft wearing apparel were tested for possible primary irritancy and allergenicity using guinea pigs and human subjects. The materials submitted for testing were: (1) blue, loosely knit fabric of a copolymer of chlorotrifluoroethylene and ethylene (CTFE), (2) a white fabric, 100% cotton double knit, treated with fire retardant Tetrakis (hydroxymethyl) phosphonium hydroxide/ammonia, and (3) a gold colored polyimide fabric. There were no adverse reactions to any of the fabrics.
Differences in surface temperature between evaporating and nonevaporating, partial- and full-thickness burn injuries were studied in 20 male, white guinea pigs. Evaporative cooling can disguise the temperature differential of the partial-thickness injury and lead to a false full-thickness diagnosis. A full-thickness burn with blister intact may retain enough heat to result in a false partial-thickness diagnosis. By the fourth postburn day, formation of a dry eschar may allow a surface temperature measurement without the complication of differential evaporation. For earlier use of thermographic information, evaporation effects must be accounted for or eliminated.
A standardized dissection and chemical analysis procedure was developed for individual animals of several species in the size range mouse to monkey (15 g to 15 kg). The standardized procedure permits rigorous comparisons to be made both interspecifically and intraspecifically of organ weights and gross chemical composition in mammalian species series, and was applied successfully to laboratory mice, hamsters, rats, guinea pigs, and rabbits, as well as to macaque monkeys. The procedure is described in detail.