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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 73 records · Page 4
All sourcesNASA NTRSDOE OSTI
NASA NTRS1986

Role of glucocorticoids in the response of rat leg muscles to reduced activity

Adrenalectomy did not prevent atrophy of rat soleus muscle during 6 days of tail cast suspension. Cortisol treatment enhanced the atrophy and caused atrophy of the weight-bearing soleus and both extensor digitorum longus (EDL) muscles. Unloading led to increased sarcoplasmic protein concentration in the soleus but cortisol administration increased the myhofibrillar (+stromal) protein concentration in both muscles. Suspension of hindlimbs of adrenalectomized animals led to faster protein degradation, slower sarcoplasmic protein degradation, and faster myofibrillar protein synthesis in the isolated soleus, whereas with cortisol-treated animals, the difference in synthesis of myofibrillar proteins was enhanced and that of sarcoplasmic proteins was abolished. Both soleus and EDL of suspended, cortisol-treated animals showed faster protein degradation. It is unlikely that any elevation in circulating glucocorticoids was solely responsible for atrophy of the soleus in this model, but catabolic amounts of glucocorticoids could alter the response of muscle to unloading.

Jaspers, Stephen R.↗
NASA NTRS1989

Atmospheric environment for space shuttle (STS-26) launch

A summary of selected atmospheric conditions observed near Space Shuttle STS-26 launch time on September 29, 1988, at Kennedy Space Center, Florida is given. Values of ambient pressure, temperature, moisture, ground winds, visual observations (cloud), and winds aloft are included. The sequence of pre-launch Jimsphere measured vertical wind profiles is given. The final atmospheric tape, which consists of wind and thermodynamic parameters versus altitude, for STS-26 vehicle ascent has been constructed. The STS-26 ascent atmospheric data tape has been constructed by Marshall Space Flight Center's Earth Science and Applications Division to provide an internally consistent data set for use in post-flight performance assessments.

Jasper, G. L.↗
NASA NTRS1989

Atmospheric environment for Space Shuttle (STS-27) launch

Selected articles on atmospheric conditions observed near Space Shuttle STS-27 launch time on December 2, 1988, at Kennedy Space Center, Florida are summarized. STS-27 carried a Department of Defense payload and the flight azimuth in this report will be denoted by reference flight azimuth, since the actual flight azimuth is not known. Values of ambient pressure, temperature, moisture, ground winds, visual observations (cloud), and winds aloft are included. The sequence of pre-launch Jimsphere-measured vertical wind profiles is given. The final atmospheric tape, which consists of wind and thermodynamic parameters versus altitude, for STS-27 vehicle ascent was constructed. The STS-27 ascent atmospheric data tape was constructed by Marshall Space Flight Center's Earth Science and Applications Division to provide an internally consistent data set for use in post-flight performance assessments.

Jasper, G. L.↗
NASA NTRS1988

Effects of immobilization on rat hind limb muscles under non-weight-bearing conditions

The effect of stretched and unstretched immobilization of a hind limb on the concentration and the metabolism of proteins in the hind-limb muscles of rats was investigated. The animals were divided into three groups: (1) weight-bearing controls, (2) tail-cast-suspended, and (3) suspended, with one hind limb immobilized with the ankle in dorsiflexion (30-40 deg angle) and the other freely moving. It was found that unloading the hind limbs for 6 days by tail cast suspension caused soleus to atrophy and reduced growth of the gastrocnemius and plantaris muscles; unloading resulted in a higher degradation rate and lower synthesis rate in both in vitro and in vivo. Chronic stretch of the unloaded soleus not only prevented its atrophy but led to significant hypertrophy, relative to weight-bearing controls, with increases in both the sarcoplasmic and myofibrillar protein fractions. Immobilizing one ankle in dorsiflexion prevented the inhibition of growth in the plantaris and gastrocnemius muscles due to unloading.

Jaspers, Stephen R.↗
NASA NTRS1988

Insulin effect on amino acid uptake by unloaded rat hindlimb muscles

The effect of insulin on the uptake of alpha-amino-isobutyric acid (AIB) by unloaded rat hindlimb muscles was investigated using soleus and extensor digitorum longus (EDL) muscles from intact and adrenalectomized (ADX) rats that were tail-casted for six days. It was found that, at insulin levels above 0.00001 units/ml, the in vitro rate of AIB uptake by muscles from intact animals was stimulated more in the weight bearing muscles than in unloaded ones. In ADX animals, this differential response to insulin was abolished.

Jaspers, S. R.↗
NASA NTRS1989

Atmospheric environment for space shuttle (STS-29) launch

This report presents a summary of selected atmospheric conditions observed near Space Shuttle STS-29 launch time on March 13, 1989, at Kennedy Space Center, Florida. Values of ambient pressure, temperature, moisture, ground winds, visual observations (cloud), and winds aloft are included. The sequence of pre-launch Jimsphere-measured vertical wind profiles is given in this report. The final atmospheric tape, which consists of wind and thermodynamic parameters versus altitude, for STS-29 vehicle ascent has been constructed. The STS-29 ascent atmospheric data tape has been constructed by Marshall Space Flight Center's Earth Science and Applications Division to provide an internally consistent data set for use in post-flight performance assessments.

Jasper, G. L.↗
NASA NTRS1989

Atmospheric environment for space shuttle (STS-30) launch

This report presents a summary of selected atmospheric conditions observed near Space Shuttle STS-30 launch time on May 4, 1989, at Kennedy Space Center, Florida. Values of ambient pressure, temperature, moisture, ground winds, visual observations (cloud), and winds aloft are included. The sequence of pre-launch Jimsphere-measured vertical wind profiles is given in this report. The final atmospheric tape, which consists of wind and thermodynamic parameters versus altitude, for STS-30 vehicle ascent has been constructed. The STS-30 ascent atmospheric data tape has been constructed by Marshall Space Flight Center's Earth Science and Applications Division to provide an internally consistent data set for use in post-flight performance assessments.

Jasper, G. L.↗
NASA NTRS1990

Atmospheric Environment for Space Shuttle (STS-28) Launch

A summary is presented of selected atmospheric conditions observed near Space Shuttle STS-28 launch time on August 8, 1989. STS-28 carried a Department of Defense payload and the flight azimuth is denoted by a reference flight azimuth, since the actual flight azimuth is not known. Values of ambient pressure, temperature, moisture, ground winds, visual observations (cloud), and winds aloft are included. The sequence of prelaunch Jimsphere-measured vertical wind profiles is given. The final atmospheric tape, which consists of wind and thermodynamic parameters versus altitude, for STS-28 vehicle ascent was constructed and represents the best estimate of the launch environment to 400,000 ft altitude that was traversed by the STS-28 vehicle. The STS-28 ascent atmospheric data tape was constructed by Marshall Space Flight Center's Earth Science and Applications Division to provide an internally consistent data set for use in post-flight performance assessments.

Jasper, G. L.↗
NASA NTRS1990

Atmospheric environment for space shuttle (STS-33) launch

A summary is presented of selected atmospheric conditions observed near space shuttle STS-33 at launch time. STS-33 carried a DOD payload and the flight azimuth is denoted by a reference flight azimuth, since the actual flight azimuth is not known. Values of ambient pressure, temperature, moisture, ground winds, visual observations (clouds), and winds aloft are included. The sequence of pre-launch Jimsphere measured vertical wind profiles is given. The final atmospheric tape, which consists of wind and thermodynamic parameters versus altitude, for STS-33 vehicle ascent, was constructed. The STS-33 ascent atmospheric data tape was constructed by NASA-Marshall to provide an internally consistent data set for use in postflight performance assessments and represents the best estimates of the launch environment to the 400,000 ft altitude that was traversed by the STS-33 vehicle.

Jasper, G. L.↗
NASA NTRS1990

Atmospheric environment for Space Shuttle (STS-32) launch

A summary of selected atmospheric conditions observed near space shuttle STS-32 launch time on January 9, 1990, at Kennedy Space Center, Florida, are presented. Values of ambient pressure, temperature, moisture, ground winds, visual observations (clouds), and winds aloft are included. The sequence of pre-launch Jimsphere-measured vertical wind profiles is also presented. The final atmospheric tape, which consists of wind and thermodynamic parameters versus altitude, for STS-32 vehicle ascent was constructed. The STS-32 ascent atmospheric data tape was constructed to provide an internally consistent data set for use in postflight performance assessments and represents the best estimate of the launch environment that was traversed by the STS-32 vehicle.

Jasper, G. L.↗
NASA NTRS1990

Atmospheric environment for Space Shuttle (STS-31) launch

A summary of selected atmospheric conditions observed near space shuttle STS-31 launch time on April 24, 1990, at Kennedy Space Center, Florida, are presented. Values of ambient pressure, temperature, moisture, ground winds, visual observations (clouds), and winds aloft are included. The sequence of pre-launch Jimsphere-measured vertical wind profiles is also presented. The final atmospheric tape, which consists if wind and thermodynamic parameters versus altitude, for STS-31 vehicle ascent was constructed. The STS-31 ascent atmospheric data tape was constructed to provide an internally consistent data set for use in postflight performance assessments and represent the best estimated of the launch environment to the 400,000 feet altitude that was traversed by the STS-31 vehicle.

Jasper, G. L.↗
NASA NTRS1990

Atmospheric environment for space shuttle (STS-36) launch

A summary of selected atmospheric conditions observed near space shuttle STS-36 launch time on February 28, 1990, at Kennedy Space Center, Florida was presented. STS-36 carried a Department of Defense payload and the flight azimuth is not known. Values of ambient pressure, temperature, moisture, ground winds, visual observations (cloud), and winds aloft are included. The sequence of pre-launch Jimsphere-measured vertical wind profiles is given. The final atmospheric tape, which consists of wind and thermodynamic parameters versus altitude, for STS-36 vehicle ascent was constructed. The STS-36 ascent atmospheric data tape was constructed to provide an internally consistent data set for use in postflight performance assessments and represent the best estimate of the launch environment to the 400,000 feet altitude that was traversed by the STS-36 vehicle.

Jasper, G. L.↗
NASA NTRS1989

Atmospheric environment for space shuttle (STS-34) launch

A summary of selected atmospheric conditions observed near space shuttle STS-34 launch time on October 18, 1989, at Kennedy Space Center, Florida is presented. Values of ambient pressure, temperature, moisture, ground winds, visual observations (clouds), and winds aloft are included. The sequence of pre-launch Jimsphere-measured vertical wind profiles is given. The final atmospheric tape, which consists of wind and thermodynamic parameters vs. altitude, for STS-34 vehicle ascent was constructed to provide an internally consistent data set for use in post-flight performance assessments. It represents the best estimates of the launch environment to the 400,000 feet altitude that was traversed by the STS-34 vehicle.

Jasper, G. L.↗
NASA NTRS1989

Metabolism of branched-chain amino acids in leg muscles from tail-cast suspended intact and adrenalectomized rats

The effects of muscle unloading, adrenalectomy, and cortisol treatment on the metabolism of branched-chain amino acids in the soleus and extensor digitorum longus of tail-cast suspended rats were investigated using C-14-labeled lucine, isoleucine, and valine in incubation studies. It was found that, compared to not suspended controls, the degradation of branched-chain amino acids in hind limb muscles was accelerated in tail-cast suspended rats. Adrenalectomy was found to abolish the aminotransferase flux and to diminish the dehydrogenase flux in the soleus. The data also suggest that cortisol treatment increases the rate of metabolism of branched-chain amino acids at the dehydrogenase step.

Jaspers, Stephen R.↗
NASA NTRS1989

Effects of stretching and disuse on amino acids in muscles of rat hind limbs

The effects of disuse and passive stretch on the concentrations of amino acids and ammonia in the unloaded soleus muscle was investigated in hindquarter-suspended (for six days by casting one foot in dorsiflexion) tail-casted rats. For a comparison with the condition of unloading, amino acids and ammonia were also measured in shortened extensor digitorum longus in the same casted limb and in denervated leg muscles. The results obtained suggest that passive stretch diminishes some of the characteristic alterations of amino acid concentrations due to unloading. This effect of stretch is considered to be due to the maintenance of muscle tension.

Jaspers, Stephen R.↗
NASA NTRS1990

Atmospheric environment for space shuttle (STS-41) launch

A summary of selected atmospheric conditions observed near space shuttle STS-41 launch time on October 6, 1990, at Kennedy Space Center, Florida are presented. Values of ambient pressure, temperature, moisture, ground winds, visual observations (clouds), and winds aloft are included. The sequence of prelaunch Jimsphere-measured vertical wind profiles is given. The final atmospheric tape, which consists of wind and thermodynamic parameters versus altitude, for STS-41 vehicle ascent was constructed. The STS-41 ascent atmospheric data tape was constructed by Marshall Space Flight Center's Earth Science and Applications Division to provide an internally consistent data set for use in postflight performance assessments and represents the best estimate of the launch environment to the 400,000 ft altitude that was traversed by the STS-41 vehicle.

Jasper, G. L.↗
NASA NTRS1990

Experiments in thrusterless robot locomotion control for space applications

While performing complex assembly tasks or moving about in space, a space robot should minimize the amount of propellant consumed. A study is presented of space robot locomotion and orientation without the use of thrusters. The goal was to design a robot control paradigm that will perform thrusterless locomotion between two points on a structure, and to implement this paradigm on an experimental robot. A two arm free flying robot was constructed which floats on a cushion of air to simulate in 2-D the drag free, zero-g environment of space. The robot can impart momentum to itself by pushing off from an external structure in a coordinated two arm maneuver, and can then reorient itself by activating a momentum wheel. The controller design consists of two parts: a high level strategic controller and a low level dynamic controller. The control paradigm was verified experimentally by commanding the robot to push off from a structure with both arms, rotate 180 degs while translating freely, and then to catch itself on another structure. This method, based on the computed torque, provides a linear feedback law in momentum and its derivatives for a system of rigid bodies.

Jasper, Warren Joseph↗
NASA NTRS1991

Atmospheric environment for space shuttle (STS-38) launch

A summary of selected atmospheric conditions observed near space shuttle STS-38 launch time on November 15, 1990, at Kennedy Space Center is presented. STS-38 carried a Department of Defense payload and the flight azimuth in this report will be denoted by a reference flight azimuth, since the actual flight azimuth is not known. Values of ambient pressure, temperature, moisture, ground winds, visual observation (cloud), and winds aloft are included. The sequence of prelaunch Jimsphere-measured vertical wind profiles is presented. The final atmospheric tape, which consists of wind and thermodynamic parameters versus altitude, for STS-38 vehicle ascent was constructed. The STS-38 ascent atmospheric data tape was constructed by Marshall Space Flight Center's Earth Science and Applications Division to provide an internally consistent data set for use in postflight performance assessments and represents the best estimate of the launch environment to the 400,000-ft altitude that was traversed by the STS-38 vehicle.

Jasper, G. L.↗