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At least 73 records · Page 4

Glucose determination in human aqueous humor with Raman spectroscopy

It has been suggested that spectroscopic analysis of the aqueous humor of the eye could be used to indirectly predict blood glucose levels in diabetics noninvasively. We have been investigating this potential using Raman spectroscopy in combination with partial least squares (PLS) analysis. We have determined that glucose at clinically relevant concentrations can be accurately predicted in human aqueous humor in vitro using a PLS model based on artificial aqueous humor. We have further determined that with proper instrument design, the light energy necessary to achieve clinically acceptable prediction of glucose does not damage the retinas of rabbits and can be delivered at powers below internationally acceptable safety limits. Herein we summarize our current results and address our strategies to improve instrument design. 2005 Society of Photo-Optical Instrumentation Engineers.

Spectrum Analysis, Raman/methods↗

Partial Least Squares and Neural Networks for Quantitative Calibration of Laser-induced Breakdown Spectroscopy (LIBs) of Geologic Samples

The ChemCam instrument [1] on the Mars Science Laboratory (MSL) rover will be used to obtain the chemical composition of surface targets within 7 m of the rover using Laser Induced Breakdown Spectroscopy (LIBS). ChemCam analyzes atomic emission spectra (240-800 nm) from a plasma created by a pulsed Nd:KGW 1067 nm laser. The LIBS spectra can be used in a semiquantitative way to rapidly classify targets (e.g., basalt, andesite, carbonate, sulfate, etc.) and in a quantitative way to estimate their major and minor element chemical compositions. Quantitative chemical analysis from LIBS spectra is complicated by a number of factors, including chemical matrix effects [2]. Recent work has shown promising results using multivariate techniques such as partial least squares (PLS) regression and artificial neural networks (ANN) to predict elemental abundances in samples [e.g. 2-6]. To develop, refine, and evaluate analysis schemes for LIBS spectra of geologic materials, we collected spectra of a diverse set of well-characterized natural geologic samples and are comparing the predictive abilities of PLS, cascade correlation ANN (CC-ANN) and multilayer perceptron ANN (MLP-ANN) analysis procedures.

Anderson, R. B.↗

New Results from Galileo's First Flyby of Ganymede: Reconnection-Driven Flows at the Low-Latitude Magnetopause Boundary, Crossing the Cusp, and Icy Ionospheric Escape

On 27 June 1996, the NASA Galileo spacecraft made humanity’s first flyby of Jupiter’s largest moon, Ganymede, discovering that it is the only moon known to possess an internally generated magnetic field. Resurrecting the original Galileo Plasma Subsystem (PLS) data analysis software, we processed the raw PLS data from G01 and for the first time present the properties of plasmas encountered. Entry into the magnetosphere of Ganymede occurred near the confluence of the magnetopause and plasma sheet. Reconnection-driven plasma flows were observed (consistent with an Earth-like Dungey cycle), which may be a result of reconnection in the plasma sheet, magnetopause, or might be Ganymede’s equivalent of a Low-Latitude Boundary Layer. Dropouts in plasma density combined with velocity perturbations afterward suggest that Galileo briefly crossed the cusps into closed magnetic field lines. Galileo then crossed the cusps, where field-aligned precipitating ions were observed flowing down into the surface, at a location consistent with observations by the Hubble Space Telescope. The density of plasma outflowing from Ganymede jumped an order of magnitude around closest approach over the north polar cap. The abrupt increase may be a result of crossing the cusp or may represent an altitude-dependent boundary such as an ionopause. More diffuse, warmer field-aligned outflows were observed in the lobes. Fluxes of particles near the moon on the nightside were significantly lower than on the dayside, possibly resulting from a diurnal cycle of the ionosphere and/or neutral atmosphere.

Collinson, Glyn↗

Survey of the plasma electron environment of Jupiter: A view from Voyager

The plasma environment within Jupiter's bow shock is considered in terms of the in situ, calibrated electron plasma measurements made between 10 eV and 5.95 keV by the Voyager plasma science experiment (PLS). Measurements were analyzed and corrected for spacecraft potential variations; the data were reduced to nearly model independent macroscopic parameters of the local electron density and temperature. It is tentatively concluded that the radial temperature profile within the plasma sheet is caused by the intermixing of two different electron populations that probably have different temporal histories and spatial paths to their local observation. The cool plasma source of the plasma sheet and spikes is probably the Io plasma torus and arrives in the plasma sheet as a result of flux tube interchange motions or other generalized transport which can be accomplished without diverting the plasma from the centrifugal equator. The hot suprathermal populations in the plasma sheet have most recently come from the sparse, hot mid-latitude "bath" of electrons which were directly observed juxtaposed to the plasma sheet.

Scudder, J. D.↗

Voyager 1 encounter with the Saturnian system

The Voyager 1 Saturn flyby mission of March 1979 is reviewed, with brief discussions of its flight, trajectory, science plan formulation and telemetered data. Analytical results of such data with respect to Saturn's atmosphere, rings, icy satellites, Titan satellite atmosphere and the Saturn magnetosphere, are summarized. The Voyager science investigations comprise imaging science (ISS), infrared radiation (IRIS), photopolarimetry (PPS), ultraviolet spectroscopy (UVS), radio science (RSS), magnetic fields (MAG), plasma particles (PLS), plasma waves (PWS), planetary radio astronomy (PRA), low energy charged particles (LECP), and cosmic-ray particles (CRS).

Stone, E. C.↗

Force balance in the magnetospheres of Jupiter and Saturn

Spacecraft measurements of the plasma populations and magnetic fields near Jupiter and Saturn have revealed that large magnetospheres surround both planets. Magnetic field measurements have indicated closed field line topologies in the dayside magnetospheres of both planets while plasma instruments have shown these regions to be populated by both hot and cold plasma components convected azimuthally in the sense of planetary rotation. By using published data from the Voyager Plasma Science (PLS), Low Energy Charged Particle (LECP), and Magnetometer (MAG) instruments, it is possible to investigate the validity of the time stationary MHD momentum equation in the middle magnetospheres of Jupiter and Saturn. At Saturn, the hot plasma population is negligible in the dynamic sense and the centrifugal force of the cold rotating plasma appears to balance the Lorentz force. At Jupiter, the centrifugal force balances about 25 percent of the Lorentz force. The remaining inward Lorentz force is balanced by pessure gradients in the hot, high-beta plasma of the Jovian magnetodisk.

Mcnutt, R. L., Jr.↗

The response function of modulated grid Faraday cup plasma instruments

Modulated grid Faraday cup plasma analyzers are a very useful tool for making in situ measurements of space plasmas. One of their great attributes is that their simplicity permits their angular response function to be calculated theoretically. An expression is derived for this response function by computing the trajectories of the charged particles inside the cup. The Voyager Plasma Science (PLS) experiment is used as a specific example. Two approximations to the rigorous response function useful for data analysis are discussed. The theoretical formulas were tested by multi-sensor analysis of solar wind data. The tests indicate that the formulas represent the true cup response function for all angles of incidence with a maximum error of only a few percent.

Barnett, A.↗

Plasma depletions in the Jovian magnetosphere - Evidence of transport and solar wind interaction

A series of plasma voids ('dropouts') was observed by the Plasma Science (PLS) experiment in Jupiter's magnetosphere during the Voyager 2 encounter with that planet. A reexamination of Voyager 2 data has led to the conclusion that the dropout phenomenon cannot be a manifestation of a plasma wake produced by Ganymede. Rather, the appearance of the dropouts is attributed to changes in the upstream solar wind conditions and the global state of the magnetosphere; the proximity of Voyager 2 to Ganymede at the time is considered to be coincidental. It is suggested that these dropouts are evidence of a state of 'bubbling' of the magnetosphere that alternates with 'laminar' states in which, as in the case of the Voyager 1 encounter with Jupiter, voids are not present and that these states correspond to different processes by which plasma is transported out of the system. The nature of these states is related to changes in the magnitude of the upstream solar wind ram pressure. In the bubbling state, this pressure is higher than in the laminar state and drives an intermittent instability. The analysis presented is one of the first attempts to introduce, in space physics, recently acquired theoretical notions of the physics of the finite-beta plasmas of which the Jovian magnetospheric plasma is an important example.

Mcnutt, Ralph L., Jr.↗

Analysis of pre-flight modulator voltage calibration data for the Voyager plasma science experiment

The Voyager Plasma Science (PLS) modulator calibration (MVM) data analysis was undertaken in order to check the correctness of the fast A/D converter formulas that connect low voltage monitor signals (MV) with digital outputs (DN), to determine the proportionality constants between the actual modulator grid potential (V) and the monitor voltage (MV), and to establish an algorithm to link the digitized readouts (DN) with the actual grid potential (V). The analysis results are surprising in that the derived conversion constants deviate by fairly significant amounts from their nominal values. However, it must be kept in mind that the test results which were used for analysis may be very imprecise. Even if it is assumed that the test result errors are very large, they do no appear to be capable to account for all discrepancies between the theoretical expectations and the results of the analysis. Measurements with the flight spare instrument appear to be the only means of investigating these effects further.

Nastov, Ognen↗

Plasma bulk flow in Jupiter's dayside middle magnetosphere

Using the plasma data obtained during the Voyager 1 encounter and the full response function of the Plasma Science (PLS) experiment, convective plasma velocities have been determined in the dayside middle magnetosphere of Jupiter (r = 10-25 Jupiter radii). It is found that temperature anisotropies have very little effect on plasma velocity determination and that the plasma data are well approximated by convected, isotropic Maxwellian ion distribution functions. The insensitivity of the analysis to any thermal anisotropies which may exist allows a good determination of the bulk plasma flow velocity. In addition to the subcorotational azimuthal flow, there exists a substantial nonazimuthal component of plasma flow. This nonazimuthal flow is mostly aligned (antialigned) with the local magnetic field but also exhibits a cross-field component. The velocity pattern is inconsistent with enhanced plasma outflow in the active sector, as suggested by the corotating convection model of plasma transport. The contribution of field-aligned flow along the curved magnetic field lines to the stress on the magnetic field is evaluated. In the region studied, such flow contributes up to one half the stress produced by the azimuthal plasma flow.

Sands, Mark R.↗

Winged cargo return vehicle. Volume 1: Conceptual design

The Advanced Design Project (ADP) allows an opportunity for students to work in conjunction with NASA and other aerospace companies on NASA Advanced Design Projects. The following volumes represent the design report: Volume 1 Conceptual Design; Volume 2 Wind Tunnel Tests; Volume 3 Structural Analysis; and Volume 4 Water Tunnel Tests. The project chosen by the University of Minnesota in conjunction with NASA Marshall Space Flight Center for this year is a Cargo Return Vehicle (CRV) to support the Space Station Freedom. The vehicle is the third generation of vehicles to be built by NASA, the first two being the Apollo program, and the Space Shuttle program. The CRV is to work in conjunction with a personnel launch system (PLS) to further subdivide and specialize the vehicles that NASA will operate in the year 2000. The cargo return vehicle will carry payload to and from the Space Station Freedom (SSF).

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Electrostatic waves in the bow shock at Uranus

Electrostatic emissions measured by the Voyager 2 plasma wave detector (PWS) during the inbound crossing of the Uranian bow shock are shown to differ in some aspects from the waves measured during bow shock crossings at Jupiter and Saturn. The wave amplitudes in the foot of the bow shock at Uranus are in general much lower than those detected at the other outer planets due to the unusually enhanced solar wind ion temperature during the crossing. This reduces the effectiveness of wave-particle interactions in heating the incoming electrons. Strong wave emissions are observed in the shock ramp that possibly arise from currents producing a Buneman mode instability. Plasma instrument (PLS) and magnetometer (MAG) measurements reveal a complicated shock structure reminiscent of computer simulations of high-Mach number shocks when the effects of anomalous resistivity are reduced, and are consistent with high ion temperatures restricting the growth of electrostatic waves.

Moses, S. L.↗

Structural design considerations for a Personnel Launch System

A vehicle capable of performing the transfer of eight people to and from the Space Station Freedom is currently in the conceptual/preliminary design stages at the NASA Langley Research Center. Structural definition of this Personnel Launch System (PLS) and the considerations leading to it are described. Issues such as cost, technology level, human factors, and maintainability are used as guidelines for the structural definition. A synergistic design technique involving aerodynamics, performance, mission, packaging, and weights and sizing analyses is utilized to evaluate the structural design. A closed-loop design is achieved when the mission requirements are met by each previously mentioned analysis for a particular vehicle weight. Although satisfactory, the structural concept presented herein is not to be treated as a final answer, but one promising solution. An examination of alternative designs and more detailed analyses can be undertaken in order to identify design inadequacies and more efficient approaches.

Bush, Lance B.↗

Design and fabrication of the NASA HL-20 full scale research model

A full-scale engineering model of the HL-20 Personnel Launch System (PLS) was constructed for systems and human factors evaluation. Construction techniques were developed to enable the vehicle to be constructed with a minimum of time and cost. The design and construction of the vehicle are described.

Driver, K. Dean↗

Investigation of microstructural changes in polyetherether-ketone films at cryogenic temperatures by positron lifetime spectroscopy

Microstructural changes in Polyetherether-ketone (PEEK) films were investigated in the temperature ranges of 23 to -196 C, using Positron Lifetime Spectroscopy (PLS) technique. It was determined that the total free volume decreases by about 46 percent in amorphous PEEK samples and about 36 percent in semicrystalline PEEK samples when they are cooled down from room temperature to liquid nitrogen (LN2) temperature. If this trend in reduction in free volume with decreasing temperature continues, as expected, it is surmised that PEEK will be able to withstand cooling down to liquid hydrogen (LH2) temperature without any detrimental effect on its diffusivity for liquid hydrogen.

Singh, Jag J.↗

Design and fabrication of the NASA HL-20 support cradle and interior mockup

An extensive test program involving analysis in both the horizontal and vertical attitudes of the HL-20 will be conducted by NASA-Langley. This necessitated the fabrication of a steel support cradle for the composite Personnel Launch System (PLS) model and an internal mockup to simulate the pilot and passenger compartments.

Exum, Thurman↗

Liquid Rocket Booster (LRB) for the Space Transportation System (STS) systems study, volume 2, addendum 2

The feasibility of developing and producing a launch vehicle from an external tank (ET) and an engine module that mounts inline to the tankage at the aft end and contains six space transportation main engines (STME), was assessed. The primary mission of this launch vehicle would be to place a PLS (personnel launch vehicle) into a low earth orbit (LEO). The vehicle tankage and the assembly of the engine module, was evaluated to determine what, if any, manufacturing/production impacts would be incurred if this vehicle were built along side the current ET at Michoud Assembly Facility. It was determined that there would be no significant impacts to produce seven of these vehicles per year while concurrently producing 12 ETs per year. Preliminary estimates of both nonrecurring and recurring costs for this vehicle concept were made.

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Evaluation of undeveloped rocket engine cycle applications to advanced transportation

Undeveloped pump-fed, liquid propellant rocket engine cycles were assessed and evaluated for application to Next Manned Transportation System (NMTS) vehicles, which would include the evolving Space Transportation System (STS Evolution), the Personnel Launch System (PLS), and the Advanced Manned Launch System (AMLS). Undeveloped engine cycles selected for further analysis had potential for increased reliability, more maintainability, reduced cost, and improved (or possibly level) performance when compared to the existing SSME and proposed STME engines. The split expander (SX) cycle, the full flow staged combustion (FFSC) cycle, and a hybrid version of the FFSC, which has a LOX expander drive for the LOX pump, were selected for definition and analysis. Technology requirements and issues were identified and analyses of vehicle systems weight deltas using the SX and FFSC cycles in AMLS vehicles were performed. A strawman schedule and cost estimate for FFSC subsystem technology developments and integrated engine system demonstration was also provided.

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