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Redshift evolution of the H I detection rate in radio-loud active galactic nuclei

We present a search for associated H I 21 cm absorption in a sample of 29 radio-loud active galactic nuclei (AGNs) at 0.7 < z < 1, carried out with the upgraded Giant Metrewave Radio Telescope. We detect H I 21 cm absorption against none of our target AGNs, obtaining 3σ upper limits to the optical depth of ≲1% per 50 km s –1 channel. The radio luminosity of our sources is lower than that of most AGNs searched for H I 21 cm absorption at similar redshifts in the literature, and, for all targets except two, the UV luminosity is below the threshold 10 23 W Hz –1 , above which the H I in the AGN environment has been suggested to be completely ionised. We stacked the H I 21 cm spectra to obtain a more stringent limit of ≈0.17% per 50 km s –1 channel on the average H I 21 cm optical depth of the sample. Furthermore, the sample is dominated by extended radio sources, 24 of which are extended on scales of tens of kiloparsecs. Including similar extended sources at 0.7 < z < 1.0 from the literature, and comparing with a low-z sample of extended radio sources, we find statistically significant (≈3σ) evidence that the strength of H I 21 cm absorption towards extended radio sources is weaker at 0.7 < z < 1.0 than at z < 0.25, with a lower detection rate of H I 21 cm absorption at 0.7 < z < 1.0. Redshift evolution in the physical conditions of H I is the likely cause of the weaker associated H I 21 cm absorption at high redshifts, due to either a low H I column density or a high spin temperature in high-z AGN environments.

79 ASTRONOMY AND ASTROPHYSICS↗

The discovery of a radio galaxy of at least 5 Mpc

Context. Giant radio galaxies (GRGs, or colloquially ‘giants’) are the Universe’s largest structures generated by individual galaxies. They comprise synchrotron-radiating active galactic nucleus ejecta and attain cosmological (megaparsec-scale) lengths. However, the main mechanisms that drive their exceptional growth remain poorly understood. Aims. To deduce the main mechanisms that drive a phenomenon, it is usually instructive to study extreme examples. If there exist host galaxy characteristics that are an important cause for GRG growth, then the hosts of the largest GRGs are likely to possess them. Similarly, if there exist particular large-scale environments that are highly conducive to GRG growth, then the largest GRGs are likely to reside in them. For these reasons, we aim to perform a case study of the largest GRG available. Methods. We reprocessed the LOFAR Two-Metre Sky Survey DR2 by subtracting compact sources and performing multi-scale CLEAN de-convolutions at 60" and 90" resolution. The resulting images constitute the most sensitive survey yet for radio galaxy lobes, whose diffuse nature and steep synchrotron spectra have allowed them to evade previous detection attempts at higher resolution and shorter wavelengths. We visually searched these images for GRGs. Results. We have discovered Alcyoneus, a low-excitation radio galaxy with a projected proper length l p = 4.99 ± 0.04 Mpc. Both its jets and lobes are detected at very high significance, and the SDSS-based identification of the host, at spectroscopic redshift z spec = 0.24674 ± 6 × 10 -5 , is unambiguous. The total luminosity density at ν = 144 MHz is L ν = 8 ± 1 × 10 25 W Hz -1 , which is below average, though near median (percentile 45 ± 3%) for GRGs. The host is an elliptical galaxy with a stellar mass M* = 2.4 ± 0.4 × 10 11 M ⊙ and a super-massive black hole mass M• = 4 ± 2 × 10 8 M ⊙ , both of which tend towards the lower end of their respective GRG distributions (percentiles 25 ± 9% and 23 ± 11%). The host resides in a filament of the Cosmic Web. Through a new Bayesian model for radio galaxy lobes in three dimensions, we estimate the pressures in the megaparsec-cubed-scale northern and southern lobes to be P min,1 = 4.8 ± 0.3 × 10 -16 Pa and P min,2 = 4.9 ± 0.6 × 10 -16 Pa, respectively. The corresponding magnetic field strengths are B min,1 = 46 ± 1 pT and B min,2 = 46 ± 3 pT. Conclusions. We have discovered what is in projection the largest known structure made by a single galaxy – a GRG with a projected proper length l p = 4.99 ± 0.04 Mpc. The true proper length is at least l min = 5.04 ± 0.05 Mpc. Beyond geometry, Alcyoneus and its host are suspiciously ordinary: the total low-frequency luminosity density, stellar mass, and super-massive black hole mass are all lower than, though similar to, those of the medial GRG. Thus, very massive galaxies or central black holes are not necessary to grow large giants, and, if the observed state is representative of the source over its lifetime, neither is high radio power. A low-density environment remains a possible explanation. The source resides in a filament of the Cosmic Web, with which it might have significant thermodynamic interaction. The pressures in the lobes are the lowest hitherto found, and Alcyoneus therefore represents the most promising radio galaxy yet to probe the warm–hot inter-galactic medium.

79 ASTRONOMY AND ASTROPHYSICS↗

FIRST J153350.8+272729: The Radio Afterglow of a Decades-old Tidal Disruption Event

We present the discovery of the fading radio transient FIRST J153350.8+272729. The source had a maximum observed 5 GHz radio luminosity of 8 × 10 39 erg s –1 in 1986, but by 2019 had faded by a factor of nearly 400. It is located at the center of a galaxy (SDSS J153350.89+272729) at 147 Mpc, which shows weak Type II Seyfert activity. We show that a tidal disruption event (TDE) is the preferred scenario for FIRST J153350.8+272729, although it could plausibly be interpreted as the afterglow of a long-duration γ-ray burst. This is only the second TDE candidate to be first discovered at radio wavelengths. Its luminosity fills a gap between the radio afterglows of subrelativistic TDEs in the local universe, and relativistic TDEs at high redshifts. The unusual properties of FIRST J153350.8+272729 (ongoing nuclear activity in the host galaxy, high radio luminosity) motivate more extensive TDE searches in untargeted radio surveys.

79 ASTRONOMY AND ASTROPHYSICS↗

Radio Afterglow Detection and AI-driven Response (RADAR): A Federated Framework for Gravitational-wave Event Follow-up

The landmark detection of both gravitational waves (GWs) and electromagnetic (EM) radiation from the binary neutron star merger GW170817 has spurred efforts to streamline the follow-up of GW alerts in current and future observing runs of ground-based GW detectors. Within this context, the radio band of the EM spectrum presents unique challenges. Sensitive radio facilities capable of detecting the faint radio afterglow seen in GW170817, and with sufficient angular resolution, have small fields of view compared to typical GW localization areas. Additionally, theoretical models predict that the radio emission from binary neutron star mergers can evolve over weeks to years, necessitating long-term monitoring to probe the physics of the various postmerger ejecta components. These constraints, combined with limited radio observing resources, make the development of more coordinated follow-up strategies essential—especially as the next generation of GW detectors promises a dramatic increase in detection rates. Here, we present RADAR, a framework designed to address these challenges by promoting community-driven information sharing, federated data analysis, and system resilience, while integrating AI methods for both GW signal identification and radio data aggregation. We show that it is possible to preserve data rights while sharing models that can help design and/or update follow-up strategies. We demonstrate our approach through a case study of GW170817, and discuss future directions for refinement and broader application.

Gravitational waves↗

Simulations of Precessing Jets and the Formation of X-shaped Radio Galaxies

Abstract Jet precession is sometimes invoked to explain asymmetries in radio galaxy (RG) jets and “X/S/Z-shaped” RGs, caused by the presence of a binary black hole companion to the source active galactic nucleus or by accretion instabilities. We present a series of simulations of RG jet precession to examine how these sources would evolve over time, including a passive distribution of cosmic-ray electrons so we can model radio synchrotron emissions and create synthetic radio maps of the sources. We find that a single source viewed from different angles can result in differing RG morphological classifications, confusing physical implications of these classifications. Additionally, the jet trajectories can become unstable due to their own self-interactions and lead to “reorientation events” that may look like the effects of external dynamics such as shocks, winds, or cold fronts in the medium. Finally, something akin to an “Odd Radio Circle” may be observed in the case of viewing the radio remnant of such a precessing source from a line of sight near the precession axis.

79 ASTRONOMY AND ASTROPHYSICS↗

RadioGalaxyNET: Dataset and novel computer vision algorithms for the detection of extended radio galaxies and infrared hosts

Abstract Creating radio galaxy catalogues from next-generation deep surveys requires automated identification of associated components of extended sources and their corresponding infrared hosts. In this paper, we introduce RadioGalaxyNET, a multimodal dataset, and a suite of novel computer vision algorithms designed to automate the detection and localization of multi-component extended radio galaxies and their corresponding infrared hosts. The dataset comprises 4 155 instances of galaxies in 2 800 images with both radio and infrared channels. Each instance provides information about the extended radio galaxy class, its corresponding bounding box encompassing all components, the pixel-level segmentation mask, and the keypoint position of its corresponding infrared host galaxy. RadioGalaxyNET is the first dataset to include images from the highly sensitive Australian Square Kilometre Array Pathfinder (ASKAP) radio telescope, corresponding infrared images, and instance-level annotations for galaxy detection. We benchmark several object detection algorithms on the dataset and propose a novel multimodal approach to simultaneously detect radio galaxies and the positions of infrared hosts.

Astronomy & Astrophysics↗

Magnetohydrodynamic simulations preliminarily predict the habitability and radio emission of TRAPPIST-1e

TRAPPIST-1e, an Earth-sized exoplanet in the habitable zone of the nearby M dwarf TRAPPIST-1, may experience magnetospheric responses that vary with stellar space weather, which could potentially influence both its habitability and radio emissions. Our objective is to investigate how different Earth-like magnetospheric configurations of TRAPPIST-1e – specifically variations in dipolar magnetic field strength and axial tilt – respond to diverse stellar space weather conditions, including events analogous to coronal mass ejections (CMEs), and to assess their implications for potential habitability and expected radio emissions. We conducted 3D magnetohydrodynamic simulations of the TRAPPIST-1e system using the PLUTO code in spherical coordinates. The planetary magnetic field was modelled as dipolar, with equatorial strengths from Earth-like to several times stronger. The dipole axis spans a representative range of axial tilts. We investigate four stellar wind environments, from sub-Alfvénic flow to CME-like disturbances. Planetary shielding was quantified based on the magnetopause standoff distance, and radio powers were estimated via empirical scaling laws. Our simulations show that both shielding and radio power depend strongly on the magnetic configuration. Stronger fields increase protection, while larger tilts reduce it. Radio power increases with both field strength and tilt across all wind regimes. An Earth-like magnetic field can provide effective shielding even under intense CMEs, whereas high tilts require stronger fields. Predicted radio powers reach ~10 20 erg s −1 during CMEs, making bursts from close-in, magnetised planets more detectable. However, for TRAPPIST-1e, the maximum cyclotron frequency lies below the Earth’s ionospheric cutoff (~10 MHz), making ground-based detection currently infeasible.

Sun: magnetic fields↗

Optical properties of Peaked Spectrum radio sources

ABSTRACT In this work, we study the optical properties of compact radio sources selected from the literature in order to determine the impact of the radio-jet in their circumnuclear environment. Our sample includes 58 Compact Steep Spectrum (CSS) and GigaHertz Peaked Spectrum (GPS) and 14 Megahertz-Peaked spectrum (MPS) radio sources located at z ≤ 1. The radio luminosity (LR) of the sample varies between Log LR ∼ 23.2 and 27.7 W Hz−1. We obtained optical spectra for all sources from SDSS-DR12 and performed a stellar population synthesis using the starlight code. We derived stellar masses (M⋆), ages 〈t⋆〉, star formation rates (SFR), metallicities 〈Z⋆〉 and internal reddening AV for all young AGNs of our sample. A visual inspection of the SDSS images was made to assign a morphological class for each source. Our results indicate that the sample is dominated by intermediate to old stellar populations and there is no strong correlation between optical and radio properties of these sources. Also, we found that young AGNs can be hosted by elliptical, spiral and interacting galaxies, confirming recent findings. When comparing the optical properties of CSS/GPS and MPS sources, we do not find any significant difference. Finally, the Mid-Infrared WISE colours analysis suggests that the compact radio sources defined as powerful AGNs are, in general, gas-rich systems.

79 ASTRONOMY AND ASTROPHYSICS↗

Discovery of a new extragalactic circular radio source with ASKAP: ORC J0102–2450

ABSTRACT We present the discovery of another odd radio circle (ORC) with the Australian Square Kilometre Array Pathfinder (ASKAP) at 944 MHz. The observed radio ring, ORC J0102–2450, has a diameter of ∼70 arcsec or 300 kpc, if associated with the central elliptical galaxy DES J010224.33–245039.5 (z ∼ 0.27). Considering the overall radio morphology (circular ring and core) and lack of ring emission at non-radio wavelengths, we investigate if ORC J0102–2450 could be the relic lobe of a giant radio galaxy seen end on or the result of a giant blast wave. We also explore possible interaction scenarios, for example, with the companion galaxy, DES J010226.15–245104.9, located in or projected on to the south-eastern part of the ring. We encourage the search for further ORCs in radio surveys to study their properties and origin.

Koribalski, Bärbel S. (ORCID:000000034351993X)↗

Demonstrating Agreement between Radio and Fluorescence Measurements of the Depth of Maximum of Extensive Air Showers at the Pierre Auger Observatory

We show, for the first time, radio measurements of the depth of shower maximum ( X max ) of air showers induced by cosmic rays that are compared to measurements of the established fluorescence method at the same location. Using measurements at the Pierre Auger Observatory we show full compatibility between our radio and the previously published fluorescence dataset, and between a subset of air showers observed simultaneously with both radio and fluorescence techniques, a measurement setup unique to the Pierre Auger Observatory. Furthermore, we show radio X max resolution as a function of energy and demonstrate the ability to make competitive high-resolution X max measurements with even a sparse radio array. With this, we show that the radio technique is capable of cosmic-ray mass composition studies, both at Auger and at other experiments. Published by the American Physical Society 2024

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Simulations of the Collision between a Debris Stream and an Outer Dusty Torus: A Possible Channel for Forming a Fast-rise and Long-delay Radio Outburst in Tidal Disruption Events

A geometrically thick dusty torus structure is believed to exist in the nuclear regions of galaxies (especially in active galactic nuclei). The debris stream from a tidal disruption event (TDE) will possibly collide with the dusty torus and produce a transient flare. We perform three-dimensional hydrodynamic simulations to model the dynamical evolution of the interaction between unbound debris and a dusty torus. During the continuous interaction, shocked material will be spilled out from the interaction region and form an outflow. We calculate the temporal evolution of synchrotron emission by assuming that the shock accelerates a fraction of electrons in the outflow into a nonthermal distribution. We find that radio emission from the debris–torus collision generates a steep-rise and slow-decline radio light curve due to the sharp edge and dense gas of the dusty torus, where the radio outburst is delayed relative to the main optical/X-ray outburst by several years or even several tens of years. We apply our model to a TDE that happened in a narrow-line Seyfert I galaxy (PS16dtm), where both the radio spectrum and the light curve can be roughly reproduced. Future high-sensitivity, wide-field-of-view radio surveys have the opportunity to detect more such radio flares.

79 ASTRONOMY AND ASTROPHYSICS↗

High-resolution Giant Metrewave Radio Telescope H I 21 cm Imaging of the Host Galaxy of FRB 20250316A

We report Giant Metrewave Radio Telescope (GMRT) H I 21 cm imaging of NGC 4141, the host galaxy of FRB 20250316A at z = 0.0063. Our GMRT H I 21 cm images have spatial resolutions, at z ≈ 0.0063, of ≈0.48–8.0 kpc, and provide evidence for (i) a companion galaxy, LEDA 2582852, to the southwest, (ii) a nearby (27 kpc distant) H i cloud to the southwest, (iii) disturbances in the H I distributions of both NGC 4141 and LEDA 2582852, and (iv) high H I column densities in the southwestern outskirts of NGC 4141. A Sloan Digital Sky Survey spectrum yields a low metallicity and a high star formation rate (SFR) surface density in the southwestern disk of NGC 4141, and an Hα-based SFR estimate that is significantly higher than that at the same location from the Galaxy Evolution Explorer near-ultraviolet image, indicating a recent burst of star formation. The total SFR of NGC 4141 is also found to be higher via the Hα line than from the 1.4 GHz radio continuum. The above evidence indicates that NGC 4141 has recently (within the last ≈3 Myr) acquired metal-poor gas, via either a merger or accretion, that resulted in the southwestern starburst and that may also have triggered large-scale star-formation activity in NGC 4141, resulting in the formation of the stellar progenitor of FRB 20250316A and the other transients. Our highest-resolution (480 pc) GMRT H I 21 cm image finds no H I 21 cm emission from the location of FRB 20250316A or the nearby star-forming region, suggesting that most of the H I here has been either ionized or converted into the molecular phase. Our nondetection of continuum emission at the location of FRB 20250316A yields the 3σ upper limit νL 1.38 GHz < 4.4 × 10 34 erg s −1 on the 1.38 GHz radio luminosity of a putative persistent radio source associated with FRB 20250316A, one of the strongest constraints on the radio luminosity of such an associated persistent radio source.

Kaur, Balpreet [Pune University (India)] (ORCID:00↗

A Unified Model of Cosmic-Ray Propagation and Radio Extreme Scattering Events from Intermittent Interstellar Structures

Intermittent magnetic structures are a plausible candidate for explaining cosmic-ray (CR) diffusion rates derived from observed CR energy spectra. Independently, studies of extreme scattering events (ESEs) of radio quasars and pulsar scintillation have hinted that very straight, large aspect ratio magnetic current sheets may be responsible for the localized large scattering of radio waves. The required shortest axis of the typical structures producing ESEs is of the same scale (∼au) as the gyroradii of ∼GeV CRs. In this Letter, we propose that the same magnetic/density sheets can produce large scattering of both CRs and radio waves. We demonstrate that the geometry and volume-filling factor of the sheets derived from quasar ESEs can explain the observed mean free path of GeV CRs without introducing free parameters. The model places constraints on the sheet geometry, such as straightness and large aspect ratio, and assumes that the statistics of the sheets are similar throughout the Galactic volume. We therefore discuss observational tests of the sheet model, which includes observations of echoes in pulsars and fast radio bursts, gravitationally lensed quasars, the distribution of ESE durations, and spatial correlations between ESE events and rotation measure fluctuations. Such tests will be enabled by upcoming wide-field radio instruments, including the Canadian Hydrogen Observatory and Radio-transient Detector and Deep Synoptic Array 2000 Antennas.

Kempski, Philipp [Princeton Univ., NJ (United Stat↗

Discovery of a nearby radio relic in the low-mass, merging cluster Abell 4067

Shock waves generated during cluster mergers offer a powerful probe of how large-scale structure grows and evolves in the Universe. As part of the MeerKAT-South Pole Telescope (SPT) survey, we report the discovery of a single arc-like radio relic in the galaxy cluster Abell 4067 ($z=0.099$), one of the lowest-mass clusters known to host such a structure. MeerKAT UHF-band (0.58–1.09 GHz) observations reveal a relic with a largest linear size of $\sim 1.48\pm 0.02$ Mpc, located at a projected distance of 0.95 Mpc from the cluster centre. XMM–Newton X-ray data show that the relic’s position and orientation relative to the intracluster medium (ICM) elongation are consistent with a merger-driven shock-wave scenario. The relic has an estimated radio power of $3.10\pm 0.03\times 10^{24}$ W Hz$^{-1}$ at 150 MHz. When placed in the $P_{150\, \mathrm{MHz}}$–$M_{500}$ scaling relation, the Abell 4067 relic appears less luminous compared to relics in more massive clusters, suggesting an association with weak merger shocks. This finding supports the idea that relics in low-mass clusters may form through less energetic merger events, leading to weak merger shocks. The latter is supported by the absence of a detectable central radio halo in Abell 4067, which reinforces the idea that luminous radio haloes are not a universal outcome of cluster mergers and highlights the role of cluster mass, merger energetics, and evolutionary stage in shaping diffuse radio emission in the ICM.

79 ASTRONOMY AND ASTROPHYSICS↗

Very Large Array imaging rules out precessing radio jets in three DES–SDSS-selected candidate periodic quasars

ABSTRACT Periodic quasars have been suggested as candidates for hosting binary supermassive black holes (SMBHs), although alternative scenarios remain possible to explain the optical light-curve periodicity. To test the alternative hypothesis of precessing radio jet, we present deep 6 GHz radio imaging conducted with NSF’s Karl G. Jansky Very Large Array (VLA) in its C configuration for the three candidate periodic quasars, DES J024703.24−010032.0, DES J024944.66−000036.8, and DES J025214.67−002813.7. Our targets were selected based on their optical variability using 20 yr long multicolour light curves from the Dark Energy Survey (DES) and the Sloan Digital Sky Survey (SDSS). The new VLA observations show that all three periodic quasars are radio-quiet with the radio loudness parameters measured to be $R\equiv f_{6\, {\rm cm}}/f_{{\rm 2500}}$ of ≲1.0–1.5 and the k-corrected luminosities νLν[6 GHz] of ≲5–21 × 1039 erg s−1. They are in stark contrast to previously known periodic quasars proposed as binary SMBH candidates such as the blazar OJ 287 and PG1302−102. Our results rule out optical emission contributed from precessing radio jets as the origin of the optical periodicity in the three DES–SDSS-selected candidate periodic quasars. Future continued optical monitoring and complementary multiwavelength observations are still needed to further test the binary SMBH hypothesis as well as other competing scenarios to explain the optical periodicity.

79 ASTRONOMY AND ASTROPHYSICS↗

A matched-filter approach to radio variability and transients: searching for orphan afterglows in the VAST Pilot Survey

Radio transient searches using traditional variability metrics struggle to recover sources whose evolution time-scale is significantly longer than the survey cadence. Motivated by the recent observations of slowly evolving radio afterglows at gigahertz frequency, we present the results of a search for radio variables and transients using an alternative matched-filter approach. We designed our matched-filter to recover sources with radio light curves that have a high-significance fit to power-law and smoothly broken power-law functions; light curves following these functions are characteristic of synchrotron transients, including ‘orphan’ gamma-ray burst afterglows, which were the primary targets of our search. Applying this matched-filter approach to data from Variables and Slow Transients Pilot Survey conducted using the Australian SKA Pathfinder, we produced five candidates in our search. Subsequent Australia Telescope Compact Array observations and analysis revealed that: one is likely a synchrotron transient; one is likely a flaring active galactic nucleus, exhibiting a flat-to-steep spectral transition over 4 months; one is associated with a starburst galaxy, with the radio emission originating from either star formation or an underlying slowly evolving transient; and the remaining two are likely extrinsic variables caused by interstellar scintillation. The synchrotron transient, VAST J175036.1–181454, has a multifrequency light curve, peak spectral luminosity, and volumetric rate that is consistent with both an off-axis afterglow and an off-axis tidal disruption event; interpreted as an off-axis afterglow would imply an average inverse beaming factor $\langle f^{-1}_{\text{b}} \rangle = 860^{+1980}_{-710}$, or equivalently, an average jet opening angle of $\langle \theta _{\textrm {j}} \rangle = 3^{+4}_{-1}\,$ deg.

79 ASTRONOMY AND ASTROPHYSICS↗

Science Uses Deployment Operations-Advanced Wireless: Exploring Open Radio Access Network Technologies for Energy Science

Open Radio Access Network is emerging as a solution to the increasing demand for more flexible, cost-effective, and advanced mobile network infrastructures. This evolution is driven by advancements in wireless technologies and the growing complexity of deploying and managing these networks. O-RAN represents a significant shift in wireless technology, building upon the 3rd Generation Partnership Project framework to foster openness, flexibility, and interoperability. By decoupling hardware and software components, Open Radio Access Network enables a multi-vendor ecosystem that encourages innovation and diverse solutions. Open Radio Access Network's potential extends beyond traditional wireless applications, with growing interest in its role in advancing energy systems, particularly in the context of smart grids, microgrids, and the integration of renewable energy sources. While the role of open-wireless technologies in driving energy transformation is increasingly recognized, further exploration is needed. Vendors and utilities are investigating how Open Radio Access Network technologies can optimize energy use cases and improve the performance of 5G and beyond applications. This report outlines efforts under the Science Uses Deployment Operations Advance Wireless project, a collaboration between the National Laboratory of the Rockies' Cybersecurity Research Center, Argonne National Laboratory, Lawrence Berkeley National Laboratory, and the Department of Energy's Energy Science Network research and operations staff. The focus of this project is on due diligence, through testing and evaluation, preparing for the deployment of advanced wireless infrastructure for scientific use cases, with an emphasis on Open Radio Access Network technology, its components, integrations, and its ability to support vertical stack application across the energy sector. Additionally, the report highlights the value cases for utilities, underscoring how adopting open wireless standards can accelerate the evolution of energy systems, foster innovation, and improve the integration of critical energy technologies.

24 POWER TRANSMISSION AND DISTRIBUTION↗

Tungsten disulfide nanotubes enhance flow-induced crystallization and radio-opacity of polylactide without adversely affecting in vitro toxicity

Treatment of vascular disease, from peripheral ischemia to coronary heart disease (CHD), is poised for transformation with the introduction of transient implants designed to “scaffold” regeneration of blood vessels and ultimately leave nothing behind. Improved materials could expand the use of these devices. Here, we examine one of the leading polymers for bioresorbable scaffolds (BRS), polylactide (PLA), as the matrix of nanocomposites with tungsten disulfide (WS 2 ) nanotubes (WSNT), which may provide mechanical reinforcement and enhance radio-opacity. We evaluate in vitro cytotoxicity using vascular cells, flow-induced crystallization and radio-opacity of PLA-WSNT nanocomposites at low WSNT concentration. A small amount of WSNT (0.1 wt%) can effectively promote oriented crystallization of PLA without compromising molecular weight. And radio-opacity improves significantly: as little as 0.5 to 1 wt% WSNT doubles the radio-opacity of PLA-WSNT relative to PLA at 17 keV. The results suggest that a single component, WSNT, has the potential to increase the strength of BRS to enable thinner devices and increase radio-opacity to improve intraoperative visualization. Here, the in vitro toxicity results indicate that PLA-WSNT nanocomposites are worthy of investigation in vivo. Although substantial further preclinical studies are needed, PLA-WSNT nanocomposites may provide a complement of material properties that may improve BRS and expand the range of lesions that can be treated using transient implants.

36 MATERIALS SCIENCE↗