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At least 73 records · Page 4

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NASA NTRS1989

The influence of atmospheric stratification on scatterometer data

The effects of atmospheric stratification and the stability of the atmospheric stratification on the scatterometer data measuring surface winds over the ocean were investigated using the boundary layer model developed by Louis (1979). A variational analysis method is proposed, which allows direct assimilation of scatterometer data. It is shown that the effect of the stability of atmospheric stratification on the wind increment is relatively small. However, it is a systematic effect, and neglecting it would consistently underestimate the winds in stable regions.

Louis, Jean-Francois↗

NASA NTRS1990

Thermal advection and stratification effects on surface winds and the low level meridional mass transport

Statistical tests are performed on the Seasat scatterometer observations to examine if and to what degree thermal advection and stratification effects manifest themselves in these remotely sensed measurements of mean wind and wind stress over the ocean. On the basis of a two layer baroclinic boundary layer model which is presented, it is shown that the thermal advection and stratification of the entire boundary layer as well as the geostrophic forcing influence the modeled near surface wind and wind stress profiles. Evidence of diurnal variation in the stratification under barotropic conditions is found in the data, with the daytime marine boundary layer being more convective than its nighttime counterpart. The temporal and spacial sampling pattern of the satellite makes it impossible to recover the full diurnal cycle, however. The observed effects of the thermal advection are shown to be statistically significant during the day (and presumed more convective) hours, causing a systematic increase in the poleward transport of mass and heat. The statistical results are in a qualitative agreement with the model simulations and cannot be reproduced in randomized control tests.

Levy, Gad↗

NASA NTRS1992

Thermal stratification potential in rocket engine coolant channels

The potential for rocket engine coolant channel flow stratification was computationally studied. A conjugate, 3-D, conduction/advection analysis code (SINDA/FLUINT) was used. Core fluid temperatures were predicted to vary by over 360 K across the coolant channel, at the throat section, indicating that the conventional assumption of a fully mixed fluid may be extremely inaccurate. Because of the thermal stratification of the fluid, the walls exposed to the rocket engine exhaust gases will be hotter than an assumption of full mixing would imply. In this analysis, wall temperatures were 160 K hotter in the turbulent mixing case than in the full mixing case. The discrepancy between the full mixing and turbulent mixing analyses increased with increasing heat transfer. Both analysis methods predicted identical channel resistances at the coolant inlet, but in the stratified analysis the thermal resistance was negligible. The implications are significant. Neglect of thermal stratification could lead to underpredictions in nozzle wall temperatures. Even worse, testing at subscale conditions may be inadequate for modeling conditions that would exist in a full scale engine.

Kacynski, Kenneth J.↗

NASA NTRS2007

An Improved Model of Cryogenic Propellant Stratification in a Rotating, Reduced Gravity Environment

This paper builds on a series of analytical literature models used to predict thermal stratification within rocket propellant tanks. The primary contribution to the literature is to add the effect of tank rotation and to demonstrate the influence of rotation on stratification times and temperatures. This work also looks levels of thermal stratification for generic propellant tanks (cylindrical shapes) over a parametric range of upper-stage coast times, heating levels, rotation rates, and gravity levels.

Oliveira, Justin↗

DOE OSTI2017

Development of a Reduced-Order Three-Dimensional Flow Model for Thermal Mixing and Stratification Simulation during Reactor Transients

Mixing, thermal-stratification, and mass transport phenomena in large pools or enclosures play major roles for the safety of reactor systems. Depending on the fidelity requirement and computational resources, various modeling methods, from the 0-D perfect mixing model to 3-D Computational Fluid Dynamics (CFD) models, are available. Each is associated with its own advantages and shortcomings. It is very desirable to develop an advanced and efficient thermal mixing and stratification modeling capability embedded in a modern system analysis code to improve the accuracy of reactor safety analyses and to reduce modeling uncertainties. An advanced system analysis tool, SAM, is being developed at Argonne National Laboratory for advanced non-LWR reactor safety analysis. While SAM is being developed as a system-level modeling and simulation tool, a reduced-order three-dimensional module is under development to model the multi-dimensional flow and thermal mixing and stratification in large enclosures of reactor systems. This paper provides an overview of the three-dimensional finite element flow model in SAM, including the governing equations, stabilization scheme, and solution methods. Additionally, several verification and validation tests are presented, including lid-driven cavity flow, natural convection inside a cavity, laminar flow in a channel of parallel plates. Based on the comparisons with the analytical solutions and experimental results, it is demonstrated that the developed 3-D fluid model can perform very well for a wide range of flow problems.

Hu, Rui↗

DOE OSTI2022

Numerical investigation of the influence of shear and thermal stratification on the wind turbine tip‐vortex stability

Summary The interaction between wind turbine wakes and atmospheric turbulence is characterised by complex dynamics. In this study, two major components of the atmospheric boundary layer dynamics have been isolated, namely, the mean velocity profile shear and the thermal stratification, to examine their impact on the near‐wake development by undertaking a series of highly resolved large‐eddy simulations. Subsequently, instantaneous flow fields are extracted from the simulations and used to conduct Fourier analysis and proper orthogonal decomposition (POD) and compute the mean kinetic energy fluxes by different POD modes to better understand the tip‐vortex instability mechanisms. Our findings indicate that shear can significantly affect the breakup of the wind turbine tip‐vortices and the shape and stable length of the wake, whereas thermal stratification seems to only have limited contribution to the spatial development of the near‐wake field. Finally, our analysis shows that the applied perturbation frequency determines the tip‐vortex breakup location as it controls the onset of the mutual inductance instability.

17 WIND ENERGY↗

DOE OSTI2019

Non-invasive Risk Stratification for Coronary Artery Disease: Is It Time for Subclassifications?

Purpose of Review: Coronary artery disease (CAD) is the leading contributor to cardiovascular disease; it is the most prevalent non-communicable disease globally and has high morbidity, mortality and health care cost. Risk stratification is defined as prevention or containment of disease prior to it occurring or progressing, and non-invasive surrogates include history, examination, biomarkers and non-invasive imaging. This review aims to highlight advancement in current diagnostic strategies and explores gaps for CAD secondary to atherosclerosis and non-obstructive vascular diseases. Recent Findings: Cardiac risk scores have largely proven inadequate in risk stratifying heterogeneous patient populations. Greater emphasis should also be provided to posttest risk stratification. Non-invasive imaging with MRI is the most accurate but least cost efficacious presently due to availability and expertise. Echocardiography and nuclear imaging have good accuracy, but radiation limits the latter. Novel echocardiographic technologies may increase its appeal. Cardiac CT angiography is increasingly promising. Summary: Non-invasive and minimally invasive imaging has significantly influenced the cost-efficacy trajectory of coronary artery disease diagnosis and management. Recent studies suggest that future guidelines will incorporate more subclassifications from the findings of these novel technologies and for more diverse patient demographics.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

DOE OSTI2019

Anti-cancer drugs-induced arterial injury: risk stratification, prevention, and treatment

Vascular side effects of standard chemotherapeutic drugs and novel anti-tumor agents complicate treatment cycles, increase non-cancer-related mortality rates, and decrease the quality of life in cancer survivors. Arterial thromboembolic events (ATEE) are associated with most anti-cancer medications. Previous articles have reported a variety of vascular events including ST-segment elevation myocardial infarction as one of the most severe acute arterial attacks. Cardiologists should play an early role in identifying those at high risk for vascular complications and tailor anti-thrombotic therapies in keeping with thromboembolic and bleeding risks. Early preventive steps and individualized chemotherapy may decrease anti-tumor treatment-related vascular events. Here, we aim to provide an extensive review of anti-tumor drug-induced vascular injury (DIVI), pathomechanisms, and risk stratification underlining arterial events. We give a summary of clinical manifestations, treatment options, and possible preventive measures of DIVI. Additionally, the treatment of modifiable risk factors and tailored choice of chemotherapy must be considered in all oncology patients to prevent DIVI. We propose a complex tool for ATEE risk stratification which is warranted for early prediction leading to less frequent complications in cancer patients.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

DOE OSTI2022

Impacts of climate change on estuarine stratification and implications for hypoxia within a shallow subtropical system

Vertical density stratification often plays an important role in the formation and expansion of coastal hypoxic zones through its effect on near-bed circulation and vertical oxygen flux. However, the impact of future climate change on estuarine circulation is widely unknown. Here, we developed and calibrated a three-dimensional hydrodynamic model for Pensacola Bay, a shallow subtropical estuary in the northeastern Gulf of Mexico. Model simulations based on years 2013–2017 were applied to examine changes in salinity, temperature, and density under future climate scenarios, including increased radiative forcing (IR) and temperature (T), increased freshwater discharge (D), sea level rise (SLR), and wind intensification (W). Simulations showed that the impacts of climate change on modeled state variables varied over time with external forcing conditions. The model demonstrated the potential for sea level rise and increased freshwater discharge to episodically increase vertical density gradients in the Bay. However, increased wind forcing destabilized vertical gradients, at times reducing the spatial extent and duration of stable stratification. For time periods with low freshwater discharge, moderate increases in wind speed (10%) can destabilize density gradients strengthened by increased discharge (10%) and sea level rise (0.48 m). In contrast, destruction of strong density gradients that form near the mid-Bay channel following flood events requires stronger wind forcing. Furthermore, these results highlight the importance of considering natural variability in freshwater and wind forcing, as well as local phenomena that are generally unresolved by global climate models.

54 ENVIRONMENTAL SCIENCES↗

DOE OSTI2018

Yield degradation in inertial-confinement-fusion implosions due to shock-driven kinetic fuel-species stratification and viscous heating

Anomalous thermonuclear yield degradation (i.e., that not describable by single-fluid radiation hydrodynamics) in Inertial Confinement Fusion (ICF) implosions is ubiquitously observed in both Omega and National Ignition experiments. Multiple experimental and theoretical studies have been carried out to investigate the origin of such a degradation. Relative concentration changes of fuel-ion species, as well as kinetically enhanced viscous heating, have been among possible explanations proposed for certain classes of ICF experiments. In this study, we investigate the role of such kinetic plasma effects in detail. To this end, we use the iFP code to perform multi-species ion Vlasov-Fokker-Planck simulations of ICF capsule implosions with the fuel comprising various hydrodynamically equivalent mixtures of deuterium (D) and helium-3 (3He), as in the original. We employ the same computational setup as in O. Larroche, which was the first to simulate the experiments kinetically. However, unlike the Larroche study, and in partial agreement with experimental data, we find a systematic yield degradation in multi-species simulations versus averaged-ion simulations when the D-fuel fraction is decreased. This yield degradation originates in the fuel-ion species stratification induced by plasma shocks, which imprints the imploding system and results in the relocation of the D ions from the core of the capsule to its periphery, thereby reducing the yield relative to a non-separable averaged-ion case. By comparing yields from the averaged-ion kinetic simulations and from the hydrodynamic scaling, we also observe yield variations associated with ion kinetic effects other than fuel-ion stratification, such as ion viscous heating, which is typically neglected in hydrodynamic implosions' simulations. Since our kinetic simulations are driven by hydrodynamic boundary conditions at the fuel-ablator interface, they cannot capture the effects of ion viscosity on the capsule compression, or effects associated with the interface, which are expected to be important. As a result, studies of such effects are left for future work.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

DOE OSTI2020

Stratification of polymer mixtures in drying droplets: Hydrodynamics and diffusion

In this work, we study the evaporation-induced stratification of a mixture of short and long polymer chains in a drying droplet using molecular simulations. We systematically investigate the effects of hydrodynamic interactions (HI) on this process by comparing hybrid simulations accounting for HI between polymers through the multiparticle collision dynamics technique with free-draining Langevin dynamics simulations neglecting the same. We find that the dried supraparticle morphologies are homogeneous when HI are included but are stratified in core–shell structures (with the short polymers forming the shell) when HI are neglected. The simulation methodology unambiguously attributes this difference to the treatment of the solvent in the two models. We rationalize the presence (or absence) of stratification by measuring phenomenological multicomponent diffusion coefficients for the polymer mixtures. The diffusion coefficients show the importance of not only solvent backflow but also HI between polymers in controlling the dried supraparticle morphology.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

DOE OSTI2025

Effect of particle shape on stratification in drying films of binary colloidal mixtures

The role of particle shape in evaporation-induced auto-stratification in polydisperse colloidal suspensions is explored with molecular dynamics simulations of mixtures of spheres and aspherical particles. A unified framework based on the competition between diffusion and diffusiophoresis is proposed to understand the effects of shape and size dispersity. In general, particles diffusing more slowly (e.g., larger particles) tend to accumulate more strongly at the evaporation front. However, larger particles have larger surface areas and therefore greater diffusiophoretic mobility. Hence, they are more likely to be driven away from the evaporation front via diffusiophoresis. For a rapidly dried bidisperse suspension containing small and large spheres, the competition leads to “small-on-top” stratification. Here, we employ a computational model in which the diffusion coefficient is inversely proportional to particle mass. For a mixture of spheres and aspherical particles with similar mass, the diffusion contrast is reduced, and the spheres are always enriched at the evaporation front as they have the smallest surface area for a given mass and, therefore, the lowest diffusiophoretic mobility. Furthermore, for a mixture of solid and hollow spheres that have the same outer radius and thus the same surface area, the diffusiophoretic contrast is suppressed, and the system is dominated by diffusion. Consequently, the solid spheres, which have a larger mass and diffuse more slowly, accumulate on top of the hollow spheres. Finally, for a mixture of thin disks and long rods that differ significantly in shape but have similar mass and surface area, both diffusion and diffusiophoresis contrasts are suppressed, and the mixture does not stratify.

Classical molecular dynamic simulations↗

DOE OSTI2022

Do ambient shear and thermal stratification impact wind turbine tip-vortex breakdown?

Modern wind turbines experience uneven inflow conditions across the rotor, due to the ambient flow’s shear and thermal stratification. Such conditions alter the shape and length of turbine wakes and thus impact the loads and power generation of downstream turbines. To this end, understanding the spatial evolution of the individual wakes under different atmospheric conditions is key to controlling and optimising turbine arrays. With this numerical study we aim to obtain a better understanding of the fundamental physics governing the near-wake dynamics of wind turbines under shear and thermal stability, by examining their tip-vortex breakup mechanisms. Our approach considers scale-resolving simulations of a single turbine wake under a linear shear profile as well as the application of harmonic tip perturbations to trigger flow instabilities. For the subsequent analysis we use the proper orthogonal decomposition (POD) method to extract coherent structures from the flow, and we also calculate mean kinetic energy fluxes to quantify each coherent structure’s contribution to wake recovery. The wake’s helical spiral is found to hinder wake recovery for all studied ambient flow conditions, whereas the mutual inductance instability has positive MKE flux leading to an enhanced wake recovery. Finally, the ambient shear has the largest impact on the local MKE flux with respect to downstream location by changing the shape of the curve and location of extrema, whereas thermal stratification has only a minimal impact on the magnitude of the near-wake local MKE flux distribution.

17 WIND ENERGY↗

DOE OSTI2023

Artificial intelligence-empowered cellular morphometric risk score improves prognostic stratification of cutaneous squamous cell carcinoma

Abstract Background Risk stratification of cutaneous squamous cell carcinoma (cSCC) is essential for managing patients. Objectives To determine if artificial intelligence and machine learning might help to stratify patients with cSCC by risk using more than solely clinical and histopathological factors. Methods We retrieved a retrospective cohort of 104 patients whose cSCCs had been excised with clear margins. Clinical and histopathological risk factors were evaluated. Haematoxylin and eosin-stained slides were scanned and analysed by an algorithm based on the stacked predictive sparse decomposition technique. Cellular morphometric biomarkers (CMBs) were identified via machine learning and used to derive a cellular morphometric risk score (CMRS) that classified cSCCs into clusters of differential prognoses. Concordance analysis, sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy were calculated and compared with results obtained with the Brigham and Women’s Hospital (BWH) staging system. The performance of the combination of the BWH staging system and the CMBs was also analysed. Results There were no differences among the CMRS groups in terms of clinical and histopathological risk factors and T-stage assignment, but there were significant differences in prognosis. Combining the CMRS with BWH staging systems increased distinctiveness and improved prognostic performance. C-indices were 0.91 local recurrence and 0.91 for nodal metastasis when combining the two approaches. The NPV was 94.41% and 96.00%, the PPV was 36.36% and 41.67%, and accuracy reached 86.75% and 89.16%, respectively, with the combined approach. Conclusions CMRS is helpful for cSCC risk stratification beyond classic clinical and histopathological risk features. Combining the information from the CMRS and the BWH staging system offers outstanding prognostic performance for patients with high-risk cSCC.

Pérez-Baena, Manuel J.↗

DOE OSTI2018

Advanced Model Developments in SAM for Thermal Stratification Analysis during Reactor Transients

21 SPECIFIC NUCLEAR REACTORS AND ASSOCIATED PLANTS↗

NASA NTRS1971

Two fluid model for thermal stratification in the Apollo cryogenic oxygen tanks

It is observed on Apollo flights that for oxygen densities greater than 42 lb/cu ft the heater operation time to achieve a desired pressure rise is half that which would be required if the energy were uniformly dispersed. A two fluid model was developed to describe this effect of stratification on the tank's pressurization behavior. The increase in pressure rise rate is attributed to compression of the bulk fluid in response to expansion of the heated fluid adjacent to the heater. It is assumed that during the heating operation the adjacent fluid retains nearly all the heater energy and has no mass interaction with the bulk fluid. The hot fluid temperatures predicted by the model are in reasonable correspondence with the observed heater temperatures. The model indicates that the fraction of the fluid interacting with the heater increases with decreasing density, from less than 0.1% at full tank to roughly 1% at 50% quantity, the lowest quantity at which stratification effects on pressure are observed.

Saxton, J. A.↗

NASA NTRS1968

Improved fluid dynamics similarity, analysis and verification. Part 5: Analytical and experimental studies of thermal stratification phenomena

The stratification behavior of a contained fluid subjected to transient free convection heat transfer was studied. A rectangular vessel was employed with heat transfer from two opposite walls of the vessel to the fluid. The wall temperature was increased suddenly to initiate the process and was then maintained constant throughout the transient stratification period. Thermocouples were positioned on a post at the center of the vessel. They were adjusted so that temperatures could be measured at the fluid surface and at specific depths beneath the surface. The predicted values of the surface temperature and the stratified layer thickness were found to agree reasonably well with the experimental measurements. The experiments also provided information on the transient centerline temperature distribution and the transient flow distribution.

Winter, E. R. F.↗

NASA NTRS1971

Heat transfer and thermal stratification in the Apollo 14 cryogenic oxygen tanks

Two significant facets of Apollo oxygen tank operation are the occurrence of thermal stratification at high fluid densities and the tendency toward high heater temperatures at low fluid densities. Some insight into the nature of these phenomena can be gained, respectively, by consideration of a two fluid stratification model and a conductive heat transfer model. The alternative of convective blowdown tank operation at low densities is briefly examined.

Fineblum, S. S.↗