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At least 73 records · Page 4

Development and Use of Mark Sense Record Cards for Recording Medical Data on Pilots Subjected to Acceleration Stress

A TIME-HONORED system of recording medical histories and the data obtained on physical and laboratory examination has been that of writing the information on record sheets that go into a folder for each patient. In order to have information which would be more readily retrieved, 'a program was initiated in 1952 by the U. S. Naval School of Aviation Medicine in connection with their "Care of the Flyer" study to place this information on machine record cards. In 1958, a machine record card method was developed for recording medical data in connection with the astronaut selection program. Machine record cards were also developed by the Aero Medical Laboratory, Wright-Patterson AFB, Ohio, and the Aviation Medical Acceleration Laboratory, Naval Air Development Center, Johnsville, Pennsylvania, for use in connection with a variety of tests including acceleration stress.1 Therefore, a variety of systems resulted in which data of a medical nature could easily be recalled. During the NASA, Ames Research Center centrifuge studies/'S the pilot subjects were interviewed after each centrifuge run, or series of runs, and subjective information was recorded in a log book by the usual history taking methods referred to above. After the methods Were reviewed, it' was recognized that a card system would be very useful in recording data from our pilots after they had been exposed to acceleration stress. Since the acceleration stress cards already developed did not meet our requirements, it was decided a different card was needed.

Smedal, Harald A.↗

Production and tests of the ADDC for the Micromegas detector of the ATLAS New Small Wheel

The Large Hadron Collider (LHC) at CERN will perform a series of upgrades to allow luminosity increases during the next physics runs expected from 2022 on. These will also significantly increase the trigger rates of all the detectors. As part of the ATLAS Phase-I upgrade, the current Small Wheel muon detectors will be replaced with state-of-the-art New Small Wheel (NSW) detectors to cope with the increased luminosity of the LHC. The Address in Real Time Data Driver Card (ADDC) is designed to transmit the trigger data from the resistive Micro-Mesh Gaseous Structure (Micromegas) detectors of the NSW. The ART ASIC on the ADDC is a customdesigned chip to receive theAddress in Real Time (ART) signals from theVMMfront-end ASIC and perform hit-selection processing. The processed trigger data is then sent to the Trigger Processor (TP) through optical links. A total of 512 ADDCs will be installed on the detector close to the front-end boards. Therefore, those cards must be able to work properly in a high radiation and magnetic field environment. Furthermore, after four rounds of prototyping, the ADDC production was launched in January of 2019. 600 ADDC boards have been produced and tested with an automated test stand. This test setup can simulate the front-end signals and provide "Level-1 Data Driver Card" (L1DDC) functions as well as part of the TP functions. Thus, the ADDC functionality and stability can be verified without the remaining NSW electronics. This paper describes the ADDC hardware prototype development, radiation and integration testing, and the ADDC automated production test procedure.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

A description of a general use automated data reduction system

A data system developed for use in tests in arc jet facilities has the flexibility to accommodate various types of data, time resolution, and number of data signals. Data are tape-recorded, because a direct link to the IBM 360/67 computer is prohibited for safety reasons. The system is analogous to manual data reduction to promote user understanding and acceptance. Data computations may be performed in an interactive ('conversational') mode, for minimum delay in data reduction, or by card input. Reduced data are listed and also stored for plotting of further computational use. Operational costs of the system are reasonable, and both large and small data reduction tasks are handled readily.

Wakefield, R. M.↗

A Portable Nitrogen Dioxide Instrument Using Cavity-Enhanced Absorption Spectroscopy

The Portable (2.7 kg) Cavity-enhanced Absorption of Nitrogen Dioxide (PCAND) instrument for measuring in situ nitrogen dioxide (NO2) was developed using incoherent, broadband cavity-enhanced absorption spectroscopy (IBBCEAS). An LED light source centered at 408 nm was coupled to a cavity 15 cm in length, achieving an effective optical pathlength of ~520 m. Our precision was measured as 94 pptv (1 s). To date, we have flown this instrument on 3 balloon and 1 UAV test flights. This instrument records data to an SD card and outputs data (via an RS232 port) to external devices including a commercial radiosonde (iMet) for real-time data downlink.

TROPOMI↗

WE-FG-BRA-04: A Portable Confocal Microscope to Image Live Cell Damage Response Induced by Therapeutic Radiation

Purpose: To construct a custom and portable fluorescence confocal laser-scanning microscope (FCLSM) that can be placed in the path of therapeutic radiation beams to study real-time radiation-induced damage response in live cells. Methods: We designed and constructed a portable FCLSM with three laser diodes for excitation (405, 488, and 635 nm). An objective lens focuses the excitation light and collects fluorescence from the sample. A pair of galvanometer mirrors scans/collects the laser beam/fluorescence along the focal plane (x/y-directions). A stepper motor stage scans in the axial direction and positions the x/y of the image field. Barrier filters and dichroic mirrors are used to route the spectral emission bands to the appropriate photodetector. An avalanche photodiode collects near-infrared fluorescence; a photodiode collects back-reflected 635 nm light; and a photomultiplier tube collects green fluorescence in the range of eGFP/eYFP. A 200-µm diameter pinhole was used to implement the confocal geometry for near-infrared and red channels and a 150-µm diameter pinhole for the green channel. Data acquisition and system control were achieved using a high-throughput data acquisition card. In-house software developed in LabVIEW was used to control the hardware, collect data from the photodetectors and reconstruct the confocal images. Results: 6 frames/s can be acquired for a 25 µm{sup 2} (128×128 pixels) field of view, visualizing the entire volume of the cell nucleus (∼10 µm depth) in <10 s. To demonstrate the usefulness of our FCLSM, we imaged gold nanoshells in live cells, radiation-induced damage in fibrosarcoma cells expressing eGFP tagged to a DNA repair protein, and neurons expressing eGFP. The system can also image particle tracks in fluorescent nuclear track detectors. Conclusion: We developed a versatile and portable FCLSM that allows radiobiology studies in live cells exposed to therapeutic radiation. The FCLSM can be placed in any vertical beam line for top-to-bottom exposures. This research was supported by the Sister Institution Network Fund and the Center for Radiation Oncology Research at The University of Texas MD Anderson Cancer Center and Cancer Prevention and Research Institute of Texas. Gabriel Sawakuchi has research support from Elekta Inc.

60 APPLIED LIFE SCIENCES↗

Arc program documentation

A description of the input and output files and the data control cards for the altimeter residual computation (ARC) computer program is given. The program acts as the final altimeter preprocessor before the data is reformatted for external users. It calculates all parameters necessary for the computation of the altimeter observation residuals and the sea surface height. Mathematical models used for calculating tropospheric refraction, geoid height, tide height, ephemeris, and orbit geometry are described.

Mcmillan, J. D.↗

Flexible Peripheral Component Interconnect Input/Output Card

The Flexible Peripheral Component Interconnect (PCI) Input/Output (I/O) Card is an innovative circuit board that provides functionality to interface between a variety of devices. It supports user-defined interrupts for interface synchronization, tracks system faults and failures, and includes checksum and parity evaluation of interface data. The card supports up to 16 channels of high-speed, half-duplex, low-voltage digital signaling (LVDS) serial data, and can interface combinations of serial and parallel devices. Placement of a processor within the field programmable gate array (FPGA) controls an embedded application with links to host memory over its PCI bus. The FPGA also provides protocol stacking and quick digital signal processor (DSP) functions to improve host performance. Hardware timers, counters, state machines, and other glue logic support interface communications. The Flexible PCI I/O Card provides an interface for a variety of dissimilar computer systems, featuring direct memory access functionality. The card has the following attributes: 8/16/32-bit, 33-MHz PCI r2.2 compliance, Configurable for universal 3.3V/5V interface slots, PCI interface based on PLX Technology's PCI9056 ASIC, General-use 512K 16 SDRAM memory, General-use 1M 16 Flash memory, FPGA with 3K to 56K logical cells with embedded 27K to 198K bits RAM, I/O interface: 32-channel LVDS differential transceivers configured in eight, 4-bit banks; signaling rates to 200 MHz per channel, Common SCSI-3, 68-pin interface connector.

Bigelow, Kirk K.↗

General Mode Scanning Probe Microscopy

A critical part of SPM measurements is the information transfer from the probe-sample junction to the measurement system. Current information transfer methods heavily compress the information-rich data stream by averaging the data over a time interval, or via heterodyne detection approaches such as lock-in amplifiers and phase-locked loops. As a consequence, highly valuable information at the sub-microsecond time scales or information from frequencies outside the measurement band is lost. We have developed a fundamentally new approach called General Mode (G-mode), where we can capture the complete information stream from the detectors in the microscope. The availability of the complete information allows the microscope operator to analyze the data via information-theory analysis or comprehensive physical models. Furthermore, the complete data stream enables advanced data-driven filtering algorithms, multi-resolution imaging, ultrafast spectroscropic imaging, spatial mapping of multidimensional variability in material properties, etc. Though we applied this approach to scanning probe microscopy, the general philosophy of G-mode can be applied to many other modes of microscopy. G-mode data is captured by completely custom software written in LabVIEW and Matlab. The software generates the waveforms to electrically, thermally, or mechanically excite the SPM probe. It handles real-time communications with the microscope software for operations such as moving the SPM probe position and also controls other instrumentation hardware. The software also controls multiple variants of high-speed data acquisition cards to excite the SPM probe with the excitation waveform and simultaneously measure multiple channels of information from the microscope detectors at sampling rates of 1-100 MHz. The software also saves the raw data to the computer and allows the microscope operator to visualize processed or filtered data during the experiment. The software performs all these features while offering a user-friendly interface.

Somnath, Suhas↗

Omega flight-test data reduction sequence

Computer programs for Omega data conversion, summary, and preparation for distribution are presented. Program logic and sample data formats are included, along with operational instructions for each program. Flight data (or data collected in flight format in the laboratory) is provided by the Ohio University Omega receiver base in the form of 6-bit binary words representing the phase of an Omega station with respect to the receiver's local clock. All eight Omega stations are measured in each 10-second Omega time frame. In addition, an event-marker bit and a time-slot D synchronizing bit are recorded. Program FDCON is used to remove data from the flight recorder tape and place it on data-processing cards for later use. Program FDSUM provides for computer plotting of selected LOP's, for single-station phase plots, and for printout of basic signal statistics for each Omega channel. Mean phase and standard deviation are printed, along with data from which a phase distribution can be plotted for each Omega station. Program DACOP simply copies the Omega data deck a controlled number of times, for distribution to users.

Lilley, R. W.↗

Fully-Coupled Fluid/Structure Vibration Analysis Using MSC/NASTRAN

MSC/NASTRAN's performance in the solution of fully-coupled fluid/structure problems is evaluated. NASTRAN is used to perform normal modes (SOL 103) and forced-response analyses (SOL 108, 111) on cylindrical and cubic fluid/structure models. Bulk data file cards unique to the specification of a fluid element are discussed and analytic partially-coupled solutions are derived for each type of problem. These solutions are used to evaluate NASTRAN's solutions for accuracy. Appendices to this work include NASTRAN data presented in fringe plot form, FORTRAN source code listings written in support of this work, and NASTRAN data file usage requirements for each analysis.

Fernholz, Christian M.↗

Digital Architecture for a Trace Gas Sensor Platform

A digital architecture has been implemented for a trace gas sensor platform, as a companion to standard analog control electronics, which accommodates optical absorption whose fractional absorbance equivalent would result in excess error if assumed to be linear. In cases where the absorption (1-transmission) is not equivalent to the fractional absorbance within a few percent error, it is necessary to accommodate the actual measured absorption while reporting the measured concentration of a target analyte with reasonable accuracy. This requires incorporation of programmable intelligence into the sensor platform so that flexible interpretation of the acquired data may be accomplished. Several different digital component architectures were tested and implemented. Commercial off-the-shelf digital electronics including data acquisition cards (DAQs), complex programmable logic devices (CPLDs), field-programmable gate arrays (FPGAs), and microcontrollers have been used to achieve the desired outcome. The most completely integrated architecture achieved during the project used the CPLD along with a microcontroller. The CPLD provides the initial digital demodulation of the raw sensor signal, and then communicates over a parallel communications interface with a microcontroller. The microcontroller analyzes the digital signal from the CPLD, and applies a non-linear correction obtained through extensive data analysis at the various relevant EVA operating pressures. The microcontroller then presents the quantitatively accurate carbon dioxide partial pressure regardless of optical density. This technique could extend the linear dynamic range of typical absorption spectrometers, particularly those whose low end noise equivalent absorbance is below one-part-in-100,000. In the EVA application, it allows introduction of a path-length-enhancing architecture whose optical interference effects are well understood and quantified without sacrificing the dynamic range that allows quantitative detection at the higher carbon dioxide partial pressures. The digital components are compact and allow reasonably complete integration with separately developed analog control electronics without sacrificing size, mass, or power draw.

Gonzales, Paula↗

Note: An improved calibration system with phase correction for electronic transformers with digital output

The existing electronic transformer calibration systems employing data acquisition cards cannot satisfy some practical applications, because the calibration systems have phase measurement errors when they work in the mode of receiving external synchronization signals. This paper proposes an improved calibration system scheme with phase correction to improve the phase measurement accuracy. We employ NI PCI-4474 to design a calibration system, and the system has the potential to receive external synchronization signals and reach extremely high accuracy classes. Accuracy verification has been carried out in the China Electric Power Research Institute, and results demonstrate that the system surpasses the accuracy class 0.05. Furthermore, this system has been used to test the harmonics measurement accuracy of all-fiber optical current transformers. In the same process, we have used an existing calibration system, and a comparison of the test results is presented. The system after improvement is suitable for the intended applications.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Stable Isotope Labeling for Improved Comparative Analysis of RNA Digests by Mass Spectrometry

Even with the advent of high throughput methods to detect modified ribonucleic acids (RNAs), mass spectrometry remains a reliable method to detect, characterize, and place post-transcriptional modifications within an RNA sequence. Here we have developed a stable isotope labeling comparative analysis of RNA digests (SIL-CARD) approach, which improves upon the original {sup 18}O/{sup 16}O labeling CARD method. Like the original, SIL-CARD allows sequence or modification information from a previously uncharacterized in vivo RNA sample to be obtained by direct comparison with a reference RNA, the sequence of which is known. This reference is in vitro transcribed using a {sup 13}C/{sup 15}N isotopically enriched nucleoside triphosphate (NTP). The two RNAs are digested with an endonuclease, the specificity of which matches the labeled NTP used for transcription. As proof of concept, several transfer RNAs (tRNAs) were characterized by SIL-CARD, where labeled guanosine triphosphate was used for the reference in vitro transcription. RNase T1 digestion products from the in vitro transcript will be 15 Da higher in mass than the same digestion products from the in vivo tRNA that are unmodified, leading to a doublet in the mass spectrum. Singlets, rather than doublets, arise if a sequence variation or a post-transcriptional modification is present that results in a relative mass shift different from 15 Da. Moreover, the use of the in vitro synthesized tRNA transcript allows for quantitative measurement of RNA abundance. Overall, SIL-CARD simplifies data analysis and enhances quantitative RNA modification mapping by mass spectrometry. .

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Inter-strand current sharing and ac loss measurements in superconducting YBCO Roebel cables

A Roebel cable, one twist pitch long, was modified from its as-received state by soldering copper strips between the strands to provide inter-strand connections enabling current sharing. Various DC transport currents (representing different percentages of its critical current) were applied to a single strand of such a modified cable at 77 K in a liquid nitrogen bath. Simultaneous monitoring of I–V curves in different parts of the strand as well as in its interconnections with other strands was made using a number of sensitive Keithley nanovoltmeters in combination with a multichannel high-speed data acquisition card, all controlled via LabView software. Current sharing onset was observed at about 1.02 of strand I c . At a strand current of 1.3I c about 5% of the current was shared through the copper strip interconnections. A finite element method modeling was performed to estimate the inter-strand resistivities required to enable different levels of current sharing. The relative contributions of coupling and hysteretic magnetization (and loss) were compared, and for our cable and tape geometry, and at dB/dt=1 T s -1 , and our inter-strand resistance of 0.77 mΩ, (enabling a current sharing of 5% at 1.3I c ) the coupling component was 0.32% of the hysteretic component. However, inter-strand contact resistance values of 100–1000 times smaller (close to those of NbTi and Nb 3 Sn based accelerator cables) would make the coupling components comparable in size to the hysteretic components.

36 MATERIALS SCIENCE↗

Inter-strand current sharing and ac loss measurements in superconducting YBCO Roebel cables

A Roebel cable, one twist pitch long, was modified from its as-received state by soldering copper strips between the strands to provide inter-strand connections enabling current sharing. Various DC transport currents (representing different percentages of its critical current) were applied to a single strand of such a modified cable at 77 K in a liquid nitrogen bath. Simultaneous monitoring of I–V curves in different parts of the strand as well as in its interconnections with other strands was made using a number of sensitive Keithley nanovoltmeters in combination with a multichannel high-speed data acquisition card, all controlled via LabView software. Current sharing onset was observed at about 1.02 of strand I c . At a strand current of 1.3I c about 5% of the current was shared through the copper strip interconnections. A finite element method modeling was performed to estimate the inter-strand resistivities required to enable different levels of current sharing. The relative contributions of coupling and hysteretic magnetization (and loss) were compared, and for our cable and tape geometry, and at dB/dt=1 T s -1 , and our inter-strand resistance of 0.77 mΩ, (enabling a current sharing of 5% at 1.3I c ) the coupling component was 0.32% of the hysteretic component. However, inter-strand contact resistance values of 100–1000 times smaller (close to those of NbTi and Nb 3 Sn based accelerator cables) would make the coupling components comparable in size to the hysteretic components.

36 MATERIALS SCIENCE↗

A digital CDS technique and its performance testing

Readout noise is a critical parameter for characterizing the performance of charge-coupled devices (CCDs), which can be greatly reduced by the correlated double sampling (CDS) circuit. However, a conventional CDS circuit inevitably introduces new noise since it consists of several active analog components such as operational amplifiers. This article proposes a digital CDS circuit technique, which transforms the pre-amplified CCD signal into a train of digital presentations by a high-speed data acquisition card directly without the noisy CDS circuit, then implements the digital CDS algorithm through a numerical method. A readout noise of 3.3 e - and an energy resolution of 121 eV@5.9 keV can be achieved via the digital CDS technique.

42 ENGINEERING↗

Data-Driven Cyber-Attack Detection for PV Farms via Time-Frequency Domain Features

The internetworking of grid-connected power electronics converters (PECs) in photovoltaic (PV) farms has inevitably expanded the cyber-attack surfaces. Here this paper presents a comprehensive study on cyber-attack detection and diagnosis for PEC-enabled PV farms via single waveform sensor to distinguish between normal conditions, open-circuit faults, short-circuit faults, and cyber-attacks. To our knowledge, this has not been attempted before. Firstly, we propose frequency-domain magnitude-based residuals to identify short-circuit faults and a time-domain mean current vector-based feature to distinguish open-circuit faults from other threats. These features can fully reflect the specific physical characteristics of PV farms during threat duration. Secondly, unlike micro phasor measurement units (µPMU) and raw electric waveform-based methods, the proposed innovative features can address novel cyber-attacks that are excluded from the training process. Thirdly, an online hardware-in-the-loop (HIL) testbed using the OPAL-RT real-time digital simulator has verified the effectiveness. The monitoring system runs in real-time while using HIL as an operational solar farm and a National Instruments (NI) data acquisition card as the electric waveform sensor at the point of coupling.

42 ENGINEERING↗