Learning to accelerate globally optimal solutions to the AC Optimal Power Flow problem
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This paper focuses on the last two stages of genome assembly, namely scaffolding and gap-filling, and shows that they can be solved as part of a single optimization problem. Our approach is based on modeling genome assembly as a problem of finding a simple path in a specific graph that satisfies as many as possible of the distance constraints encoding the insert-size information. We formulate it as a mixed-integer linear programming problem and apply an optimization solver to find the exact solutions on a benchmark of chloroplasts. We show that the presence of repetitions in the set of unitigs is the main reason for the existence of multiple equivalent solutions that are associated to alternative subpaths. We also describe two sufficient conditions and we design efficient algorithms for identifying these subpaths. Comparisons of the results achieved by our tool with the ones obtained with recent assemblers are presented.
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This award allowed Massachusetts Institute of Technology to demonstrate a number of key objectives. The focus of the project was on building a machine learning (ML) enhanced tools to accelerate the development of catalysts that promote the oxygen evolution reaction (OER) or the oxygen reduction reaction (ORR).
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(Previously announced in STAR as N81-13673)
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In this paper, an algorithm is introduced to find a minimum phase transfer function of specified order whose magnitude "tightly" overbounds a specified real-valued nonparametric function of frequency. This method has direct application to transforming nonparametric uncertainty bounds (available from system identification experiments and/or plant modeling) into parametric representations required for modern robust control design software (i.e., a minimum-phase transfer function multiplied by a norm-bounded perturbation).
While the response surface method is an effective method in engineering optimization, its accuracy is often affected by the use of limited amount of data points for model construction. In this chapter, the issues related to the accuracy of the RS approximations and possible ways of improving the RS model using appropriate treatments, including the iteratively re-weighted least square (IRLS) technique and the radial-basis neural networks, are investigated. A main interest is to identify ways to offer added capabilities for the RS method to be able to at least selectively improve the accuracy in regions of importance. An example is to target the high efficiency region of a fluid machinery design space so that the predictive power of the RS can be maximized when it matters most. Analytical models based on polynomials, with controlled level of noise, are used to assess the performance of these techniques.
Single trial evaluations Trial creation by Phase-wise GA-style or DE-inspired recombination Bin repository structure requires an initialization period Non-exclusionary Kill Distance Population collapse mechanic Main loop Creation Probabilistic switch between GA and DE creation types Locally optimize Submit to repository Repeat.
Low-thrust electric propulsion provides many advantages for mission to difficult targets-Comets and asteroids-Mercury-Outer planets (with sufficient power supply)Low-thrust electric propulsion is characterized by high power requirements but also very high specific impulse (Isp), leading to very good mass fractions. Low-thrust trajectory design is a very different process from chemical trajectory.
The coronal magnetic field directly or indirectly affects a majority of the phenomena studied in the heliosphere. It provides energy for coronal heating, controls the release of coronal mass ejections, and drives heliospheric and magnetospheric activity, yet the coronal magnetic field itself has proven difficult to measure. This difficulty has prompted a decades-long effort to develop accurate, timely, models of the field, an effort that continues today. We have developed a method for improving global coronal magnetic field models by incorporating the type of morphological constraints that could be derived from coronal images. Here we report promising initial tests of this approach on two theoretical problems, and discuss opportunities for application.
With the advancement in high performance computing and numerical optimization techniques,engineering design optimization problems are becoming more complex, larger scale,higher fidelity, and computationally more demanding, requiring longer run times than ever before. There exists methodologies and techniques that can address some of these challenges but very few can address all, and most are limited in the extent that these concerns can be addressed. With the goal of addressing such challenging engineering problems, we developed anew optimization framework, named AMIEGO, that combines concepts from surrogate-based optimization approaches, gradient-based numerical methods, Partial Least Squares, evolutionary algorithms, and Branch-and-Bound, providing newer capabilities that were not previouslyperceived. However, the original version of this framework, in the process of adaptive samplingto explore and exploit the design space, finds only a single sample point per iteration. The efforthere builds upon this previously developed optimization framework to include multiple infillsampling capability that combines the concept of generalized expected improvement function,unsupervised learning, and multi-objective evolutionary technique. To demonstrate, AMIEGOwith the multiple infill capability (called AMIEGO-MIMOS) solves a series of increasingly difficultengineering design optimization problems. The results reveal the performance of the newapproach is problem dependent. When applied to a ten-bar truss problem, the newly proposedmultiple infill strategy consistently leads to a better design solutions when compared to theexisting CPTV method (implemented with the context of the AMIEGO framework). On theother hand, when applied to a mixed-integer high fidelity wing topology optimization problem- MIMOS, despite showing a steeper convergence at the start, eventually leads to an inferiorsolution as compared to CPTV approach. These results also reveal that a small number ofstarting points, in general, are sufficient to lead to a good overall solution.
An algorithm is introduced to find a minimum phase trqansfer function of specified order whose magnitude