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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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64 records · Page 4
All sourcesNASA NTRSDOE OSTI
DOE OSTI2020

High-Brightness Self-seeded X-ray Free Electron Laser to Precisely Map Macromolecular Structure

Two datasets were uploaded. Run numbers #r0101~#r0112 were collected from self-seeded XFEL mode. Run numbers #r0079~#r0088 and #r0090 were collected from SASE mode. The run number is shown in the file name as "ue_191027_SFX_runnumber-c00.cxi.". To understand the effect of self-seeded XFEL source, we used the datasets from run numbers #r0102 to #r0112. Datasets used were randomly chosen. - SS1 is from #r0102~#r0112. - SS2 is from #r0102~#r0105 and #r0109. - SS3 is from #r0104 and #r0105. To compare self-seeded mode and SASE mode, we also used corresponding three SASE datasets labeled as SASE1, SASE2, and SASE3 from run numbers #r0079 to #r0089. Datasets used were randomly chosen. - SASE1 is from #r0079~#r0089. - SASE2 is from #r0080, #r0081, #r0085, #r0087. - SASE3 is composed of #r0079, #r0080.

Lysozyme↗
DOE OSTI2021

Repulsive expansion dynamics in colony growth and gene expression

Spatial expansion of a population of cells can arise from growth of microorganisms, plant cells, and mammalian cells. It underlies normal or dysfunctional tissue development, and it can be exploited as the foundation for programming spatial patterns. This expansion is often driven by continuous growth and division of cells within a colony, which in turn pushes the peripheral cells outward. This process generates a repulsion velocity field at each location within the colony. Here we show that this process can be approximated as coarse-grained repulsive-expansion kinetics. This framework enables accurate and efficient simulation of growth and gene expression dynamics in radially symmetric colonies with homogenous z-directional distribution. It is robust even if cells are not spherical and vary in size. The simplicity of the resulting mathematical framework also greatly facilitates generation of mechanistic insights.

59 BASIC BIOLOGICAL SCIENCES↗