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A reliable nondestructive evaluation (NDE) technique provides minimum 90% probability of detection (POD) with 95% confidence for detection of cracklike flaws of a specific size. This requirement comes from fracture control. Fracture control is a risk assessment and control approach for preventing structural failure of fracture critical hardware during its service life. One of the approaches of fracture control is damage tolerance safe life analysis, which assumes that NDE reliably detectable size flaw may exist in the hardware post nondestructive evaluation. Analysis and/or testing are performed to verify that the hardware will not fail during its service life despite existence of such a flaw. NDE methods are conventionally qualified by probability of detection (POD) demonstration testing to ensure reliable flaw detection. Here, a novel and alternative to POD flaw detection reliability approach that uses contrast-to-noise ratio (CNR) is given. The approach uses CNR sensitivity function (SF) and CNR. CNR SF is the minimum CNR needed for reliable flaw detection as a function of certain flaw indication characteristics. Primary difference between POD approaches and CNR flaw detection reliability approach is resolution of flaw detection system. POD approach does not account for the resolution of the system, while CNR approach accounts for the flaw detection resolution. Resolution is determined from the modulation transfer function (MTF) of the flaw detection system. CNR flaw detection reliability approach emphasizes quantitative assessment of “how well each flaw indication is detected”. Therefore, CNR approach is helpful in reducing number of flaws in the sample used in NDE procedure qualification, resulting in cost and time savings. CNR approach is also a case of multi-hit flaw detection analysis which has better flaw detectability size than conventional single-hit flaw detectability. Thus, CNR approach, where applicable, may be superior to conventional POD approach. The paper is an overview of development of CNR modeling, CNR SF modeling and measurement by the author. The paper gives key references to currently used NDE procedure POD qualification approaches including those specific to CNR and CNR SF development in multi-hit flaw detection in NDE. The paper covers core topics in nondestructive evaluation engineering.