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At least 73 records · Page 4

Repairing Fractured Bones by Use of Bioabsorbable Composites

A proposed method of surgical repair of fractured bones would incorporate recent and future advances in the art of composite materials. The composite materials used in this method would be biocompatible and at least partly bioabsorbable: that is, during the healing process following surgery, they would be wholly or at least partly absorbed into the bones and other tissues in which they were implanted. Relative to the traditional method, the proposed method would involve less surgery, pose less of a risk of infection, provide for better transfer of loads across fracture sites, and thereby promote better healing while reducing the need for immobilization by casts and other external devices. One requirement that both the traditional and proposed methods must satisfy is to fix the multiple segments of a broken bone in the correct relative positions. Mechanical fixing techniques used in the traditional method include the use of plates spanning the fracture site and secured to the bone by screws, serving of wire along the bone across the fracture site, insertion of metallic intramedullary rods through the hollow portion of the fractured bone, and/or inserting transverse rods through the bone, muscle, and skin to stabilize the fractured members. After the bone heals, a second surgical operation is needed to remove the mechanical fixture(s). In the proposed method, there would be no need for a second surgical operation. The proposed method is based partly on the observation that in the fabrication of a structural member, it is generally more efficient and reliable to use multiple small fasteners to transfer load across a joint than to use a single or smaller number of larger fasteners, provided that the stress fields of neighboring small fasteners do not overlap or interact. Also, multiple smaller fasteners are more reliable than are larger and fewer fasteners. However, there is a trade-off between structural efficiency and the cost of insertion time and materials. The proposed method is further based partly on the conjecture that through-the-thickness reinforcements could be excellent for fixing bone segments for surgical repair. The through-the-thickness reinforcements would superficially resemble nails in both form and function. Denoted small-diameter rods (SDRs) to distinguish them from other narrow rods, these reinforcements would be shot or otherwise inserted through adjacent segments of fractured bone to fix them in their correct relative positions (see figure). Shot insertion would be effected by use an applicator that would amount to a miniaturized and highly refined version of the pneumatic guns often used in carpentry to drive nails and brads. The applicator, envisioned to be about the size of a ball-point-pen, would be driven by pressurized carbon dioxide. To further promote stabilization of the segments, layers of bone glue could be applied to the fracture surfaces prior to insertion of the SDRs. The bone glue could be therapeutically loaded with chemicals to promote growth of bone and fight infection

Farley, Gary L.↗

OCI Geolocation Evaluation and Refinement Using Landsat Control Points

The Plankton, Aerosol, Cloud, and ocean Ecosystem (PACE) mission is NASA’s next investment in ocean biology, clouds, and aerosol data records. A key feature of PACE is the inclusion of an advanced satellite radiometer, Ocean Color Instrument (OCI), a global mapping radiometer that combines multispectral and hyperspectral remote sensing. The geolocation processing is performed for OCI using spacecraft navigation data and an instrument geometry model. To evaluate the geolocation accuracy for OCI and develop refinements to the processing methods, control point matching using Landsat data has been implemented as a step in the operational processing of OCI data at the Science Data Segment. This processing provides between 200 and 300 high-quality matchups per day with good global and geometric distribution, allowing rapid evaluation of the OCI geolocation accuracy. The results provided an early indication of the overall quality of the geolocation processing and of specific aspects needing improvement. A standard set of granules was identified to support rapid implementation and testing of geolocation refinements, and this approach has been highly successful in improving the geolocation processing accuracy to meet the science requirements. The evaluation will continue throughout the mission to ensure the ongoing accuracy of geolocation. This paper describes the control point matching methodology, the approach to development of the geolocation processing refinements, and the recent results.

PACE↗

OCI Geolocation Evaluation and Refinement Using Landsat Control Points

The Plankton, Aerosol, Cloud, and ocean Ecosystem (PACE) mission is NASA’s next investment in ocean biology, clouds, and aerosol data records. A key feature of PACE is the inclusion of an advanced satellite radiometer, Ocean Color Instrument (OCI), a global mapping radiometer that combines multispectral and hyperspectral remote sensing. The geolocation processing is performed for OCI using spacecraft navigation data and an instrument geometry model. To evaluate the geolocation accuracy for OCI and develop refinements to the processing methods, control point matching using Landsat data has been implemented as a step in the operational processing of OCI data at the Science Data Segment. This processing provides between 200 and 300 high-quality matchups per day with good global and geometric distribution, allowing rapid evaluation of the OCI geolocation accuracy. The results provided an early indication of the overall quality of the geolocation processing and of specific aspects needing improvement. A standard set of granules was identified to support rapid implementation and testing of geolocation refinements, and this approach has been highly successful in improving the geolocation processing accuracy to meet the science requirements. The evaluation will continue throughout the mission to ensure the ongoing accuracy of geolocation. This paper describes the control point matching methodology, the approach to development of the geolocation processing refinements, and the recent results.

PACE↗

Current Status of NASA's Heavy Lift Plans

Numerous studies since the Apollo Program of the 1960s have highlighted the benefits of - and the need for - a national heavy lift launch capability to support human exploration, science, national security, and commercial development of space. NASA's most recent and most refined effort to develop that heavy lift capability is the Ares V. Ares V is a key element of NASA's Constellation Program. It s overall goal s part of approved national space policy is to retire the Space Shuttle and develop its successor, complete the International Space Station, and resume human exploration beyond low Earth orbit (LEO), beginning with exploration of the Moon as a step to other destinations in the Solar System. Ares V s first role is that of cargo vehicle to carry a lunar lander into Earth orbit, rendezvous with astronauts launched on the smaller Ares I crew launch vehicle, and perform the trans lunar injection (TLI) mission to send the mated crew and lander vehicles to the Moon. The design reference missions (DRMs) envisioned for it also include direct lunar cargo flights and a human Mars mission. Although NASA's priority from the start of the Constellation Program to the present has been development of the Ares I and Orion crew vehicle to replace the retiring Shuttle fleet, the Ares team has made significant progress in understanding the performance, design trades, technology needs, mission scenarios, ground and flight operations, cost, and other factors associated with heavy lift development. The current reference configuration was selected during the Lunar Capabilities Concept Review (LCCR) in fall 2008. That design has served since then as a point of departure for further refinements and trades among five participating NASA field centers. Ares V development to date has benefited from progress on the Ares I due to commonality between the vehicles. The Ares I first stage completed a successful firing of a 5-segment solid rocket motor. The Ares I-X launch Numerous studies since the Apollo Program of the 1960s have highlighted the benefits of and the need for - a national heavy lift launch capability to support human exploration, science, national security, and commercial development of space. NASA s most recent and most refined effort to develop that heavy lift capability is the Ares V. Ares V is a key element of NASA s Constellation Program. It s overall goal s part of approved national space policy is to retire the Space Shuttle and develop its successor, complete the International Space Station, and resume human exploration beyond low Earth orbit (LEO), beginning with exploration of the Moon as a step to other destinations in the Solar System. Ares V s first role is that of cargo vehicle to carry a lunar lander into Earth orbit, rendezvous with astronauts launched on the smaller Ares I crew launch vehicle, and perform the trans lunar injection (TLI) mission to send the mated crew and lander vehicles to the Moon. The design reference missions (DRMs) envisioned for it also include direct lunar cargo flights and a human Mars mission. Although NASA s priority from the start of the Constellation Program to the present has been development of the Ares I and Orion crew vehicle to replace the retiring Shuttle fleet, the Ares team has made significant progress in understanding the performance, design trades, technology needs, mission scenarios, ground and flight operations, cost, and other factors associated with heavy lift development. The current reference configuration was selected during the Lunar Capabilities Concept Review (LCCR) in fall 2008. That design has served since then as a point of departure for further refinements and trades among five participating NASA field centers. Ares V development to date has benefited from progress on the Ares I due to commonality between the vehicles. The Ares I first stage completed a successful firing of a 5-segment solid rocket motor. The Ares I-X launch successfully demonstrated in suborbital flighhe ability to assemble, prepare, launch, control and recover the Ares I configuration and compare performance to computer models. Component tests continue on the J-2X engine, which will put both the Ares I and Ares V upper stages into orbit. In addition, more than 100,000 parts have been manufactured or on the assembly line for the first J-2X powerpack and the first two development engines, with hot fire tests to begin in 2011. This paper will further detail the progress to date on the Ares V and planned activities for the remainder of 2010. In addition, the Ares V team has continued its outreach to potential user communities in science and national security. Through the Constellation Program, NASA has amassed an enormous knowledge base in the design, technologies, and operations of heavy lift launch vehicles that will be a national asset for any future launch vehicle decision. This early phase of the design presents the best opportunity to incorporate where possible the insights and needs of other users.

Creech, Steve↗

Magnetic mesh generation and field line reconstruction for scrape-off layer and divertor modeling in stellarators

The design of divertor targets and baffles for optimal heat and particle exhaust from magnetically confined fusion plasmas requires a combination of fast, low-fidelity models (such as EMC3-Lite (Feng 2022 Plasma Phys. Control. Fusion 64 125012)) for scoping studies and high-fidelity ones (such as EMC3-EIRENE (Feng et al 2014 Contrib. Plasma Phys. 54 426–31)) for verification. Both of those approaches benefit from a magnetic flux tube mesh for fast interpolation and mapping of field line segments (Feng et al 2005 Phys. Plasmas 12 052505). A new automated mesh generator for unstructured quadrilateral flux tubes with adaptive refinement is presented and integrated into FLARE (Frerichs 2024 Nucl. Fusion 64 106034). For HSX with an extended first wall, it is found that several layers of flux tubes can span the entire half field period before splitting is required. This is an advantage over the traditional setup of the EMC3-EIRENE mesh where careful construction of several sub- domains is required already for the much tighter present first wall. In particular, there is no longer the need to manually construct a suitable outer boundary for the mesh. The divide and conquer paradigm with unstructured mesh layout offers a powerful alternative for fast head load approximation that is suitable for integration into optimization workflows. Further examples for W7-X and CTH demonstrate the versatile application range.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Stereo-Optic High Definition Imaging: A New Technology to Understand Bird and Bat Avoidance of Wind Turbines

There is a critical need to develop monitoring tools to track aerofauna (birds and bats) in three dimensions around wind turbines. New monitoring systems will reduce permitting uncertainty by increasing the understanding of how birds and bats are interacting with wind turbines, which will improve the accuracy of impact predictions. Biodiversity Research Institute (BRI), The University of Maine Orono School of Computing and Information Science (UMaine SCIS), HiDef Aerial Surveying Limited (HiDef), and SunEdison, Inc. (formerly First Wind) responded to this need by using stereo-optic cameras with near-infrared (nIR) technology to investigate new methods for documenting aerofauna behavior around wind turbines. The stereo-optic camera system used two synchronized high-definition video cameras with fisheye lenses and processing software that detected moving objects, which could be identified in post-processing. The stereo- optic imaging system offered the ability to extract 3-D position information from pairs of images captured from different viewpoints. Fisheye lenses allowed for a greater field of view, but required more complex image rectification to contend with fisheye distortion. The ability to obtain 3-D positions provided crucial data on the trajectory (speed and direction) of a target, which, when the technology is fully developed, will provide data on how animals are responding to and interacting with wind turbines. This project was focused on testing the performance of the camera system, improving video review processing time, advancing the 3-D tracking technology, and moving the system from Technology Readiness Level 4 to 5. To achieve these objectives, we determined the size and distance at which aerofauna (particularly eagles) could be detected and identified, created efficient data management systems, improved the video post-processing viewer, and attempted refinement of 3-D modeling with respect to fisheye lenses. The 29-megapixel camera system successfully captured 16,173 five-minute video segments in the field. During nighttime field trials using nIR, we found that bat-sized objects could not be detected more than 60 m from the camera system. This led to a decision to focus research efforts exclusively on daytime monitoring and to redirect resources towards improving the video post- processing viewer. We redesigned the bird event post-processing viewer, which substantially decreased the review time necessary to detect and identify flying objects. During daytime field trials, we determine that eagles could be detected up to 500 m away using the fisheye wide-angle lenses, and eagle-sized targets could be identified to species within 350 m of the camera system. We used distance sampling survey methods to describe the probability of detecting and identifying eagles and other aerofauna as a function of distance from the system. The previously developed 3-D algorithm for object isolation and tracking was tested, but the image rectification (flattening) required to obtain accurate distance measurements with fish-eye lenses was determined to be insufficient for distant eagles. We used MATLAB and OpenCV to improve fisheye lens rectification towards the center of the image, but accurate measurements towards the image corners could not be achieved. We believe that changing the fisheye lens to rectilinear lens would greatly improve position estimation, but doing so would result in a decrease in viewing angle and depth of field. Finally, we generated simplified shape profiles of birds to look for similarities between unknown animals and known species. With further development, this method could provide a mechanism for filtering large numbers of shapes to reduce data storage and processing. These advancements further refined the camera system and brought this new technology closer to market. Once commercialized, the stereo-optic camera system technology could be used to: a) research how different species interact with wind turbines in order to refine collision risk models and inform mitigation solutions; and b) monitor aerofauna interactions with terrestrial and offshore wind farms replacing costly human observers and allowing for long-term monitoring in the offshore environment. The camera system will provide developers and regulators with data on the risk that wind turbines present to aerofauna, which will reduce uncertainty in the environmental permitting process.

Adams, Evan↗

Analytical and experimental studies of acoustic performance of segmented liners in a compressor inlet

The performance of axially segmented (phased) acoustic treatment liners in the inlet of a compressor was investigated. Topics discussed include: (1) the validation of a theoretical procedure to predict propagation and suppression characteristics of duct liners; (2) the in-duct measurement of spinning modes; (3) investigation of phased treatment designs; (4) high Mach inlet acoustic tests; and (5) an experimental investigation of inlet turbulence. The analytical prediction for the multi-segmented treatment was found to provide the correct order of magnitude of suppression and was generally within 50% of that determined experimentally. Refinements required to improve the correlation are identified. Suppression due to high subsonic Mach number flow effects was found to become significant above an average throat Mach number of 0.65 to 0.7 and 20 PNdB was achieved with an average throat Mach number in the range of 0.80 to 0.85. For the measured turbulence in the inlet, including the axial and circumferential turbulence intensities and the axial integral length scale, data are presented with and without an inlet screen showing that the screen reduced the turbulence intensities and that the BPF noise was reduced as a consequence.

Motsinger, R. E.↗

Data-Analysis System for Entry, Descent, and Landing

A report describes the Entry Descent Landing Data Analysis (EDA), which is a system of signal-processing software and computer hardware for acquiring status data conveyed by multiple-frequency-shift-keying tone signals transmitted by a spacecraft during descent to the surface of a remote planet. The design of the EDA meets the challenge of processing weak, fluctuating signals that are Doppler-shifted by amounts that are only partly predictable. The software supports both real-time and post processing. The software performs fast-Fourier-transform integration, parallel frequency tracking with prediction, and mapping of detected tones to specific events. The use of backtrack and refinement parallel-processing threads helps to minimize data gaps. The design affords flexibility to enable division of a descent track into segments, within each of which the EDA is configured optimally for processing in the face of signal conditions and uncertainties. A dynamic-lock-state feature enables the detection of signals using minimum required computing power less when signals are steadily detected, more when signals fluctuate. At present, the hardware comprises eight dual-processor personal-computer modules and a server. The hardware is modular, making it possible to increase computing power by adding computers.

Pham, Timothy↗

Hover Performance of Isolated Proprotors and Propellers - Experimental Data

The use of Computational Fluid Dynamics (CFD) is gaining momentum within the aeronautical community. A relatively small segment of this community is applying CFD technology in the prediction of VSTOL aircraft performance. An even smaller group of engineers are refining and applying fluid dynamics solvers to the problem of predicting hover performance of helicopter rotors and proprotors designed by rotorcraft advocates. This small group of CFD engineers who are attacking the hover performance problem have, today, been using a quite limited experimental data base upon which to demonstrate their progress. This is because their concentration has been on only two successful tiltrotor flying; namely the XV-15 and the MV-22B. No attention appears (as yet) to be directed at the CL-84 or the XC-142A. The purpose of this report is to expand the experimental data base of both proprotors and propellers so that comparisons of test and various theories can be made to several more configurations of these propulsive devices used by VSTOL aircraft.

Hover↗

Test and characterization of finely segmented pixel CZT detectors for future hard x-ray missions

The NuSTAR (Nuclear Spectroscopic Telescope Array) mission was launched in 2012, and it has successfully deployed the first orbiting telescopes to focus high energy X-ray (3 - 79 keV) light, providing a wealth of new information on high-energy X-rays sources. Follow-up missions, such as the proposed HEX-P, BEST, and FORCE, could perform a deeper black hole census providing a more refined measurement of black hole spins, allowing for greater knowledge about supermassive black holes. Here, these missions are motivated by the recent breakthroughs in the hard X-ray mirror technologies, where mirrors, either made of monolithic silicon segments, or made directly or via replication of shells, demonstrate the feasibility of making hard X-ray mirrors with angular resolutions of 5-10 arc-seconds Half Power Diameter (HPD) compared to the NuSTAR’s 1 arc-minute HPD. Such a high angular resolution requires matched detectors with higher degree of segmentation to fully benefit from the achievable improved spatial resolution. In the above framework, the HEXID ASIC, a novel pixelated front-end suitable for reading out a finely segmented CZT sensor with 150 μm pixel pitch in a hexagonal arrangement has been developed. This readout pixelated chip is capable of processing photon-generated charge packets over a large dynamic range (from 2 keV up to 180 keV), while keeping a low input noise (ENC <20 e - ). In this work, the initial characterization of the ASIC prototype will be presented.

47 OTHER INSTRUMENTATION↗

Indigenous lunar construction materials

The utilization of local resources for the construction and operation of a lunar base can significantly reduce the cost of transporting materials and supplies from Earth. The feasibility of processing lunar regolith to form construction materials and structural components is investigated. A preliminary review of potential processing methods such as sintering, hot-pressing, liquification, and cast basalt techniques, was completed. The processing method proposed is a variation on the cast basalt technique. It involves liquification of the regolith at 1200-1300 C, casting the liquid into a form, and controlled cooling. While the process temperature is higher than that for sintering or hot-pressing (1000-1100 C), this method is expected to yield a true engineering material with low variability in properties, high strength, and the potential to form large structural components. A scenario for this processing method was integrated with a design for a representative lunar base structure and potential construction techniques. The lunar shelter design is for a modular, segmented, pressurized, hemispherical dome which could serve as habitation and laboratory space. Based on this design, estimates of requirements for power, processing equipment, and construction equipment were made. This proposed combination of material processing method, structural design, and support requirements will help to establish the feasibility of lunar base construction using indigenous materials. Future work will refine the steps of the processing method. Specific areas where more information is needed are: furnace characteristics in vacuum; heat transfer during liquification; viscosity, pouring and forming behavior of molten regolith; design of high temperature forms; heat transfer during cooling; recrystallization of basalt; and refinement of estimates of elastic moduli, compressive and tensile strength, thermal expansion coefficient, thermal conductivity, and heat capacity. The preliminary design of the lunar shelter showed us that joining is a critical technology needed for building a structure from large segments. The problem of joining is important to the design of any structure that is not completely prefabricated. It is especially important when the structure is subjected to tensile loading by an internal pressure. For a lunar shelter constructed from large segments the joints between these large segments must be strong, and they must permit automated construction. With a cast basalt building material which is brittle, there is the additional problem of connecting the joint with the material and avoiding stress concentration that would cause failure. Thus, a well-defined project which we intend to pursue during this coming year is the design of joints for cast basalt structural elements.

Rogers, Wayne P.↗

Two-polarity magnetization in the Manson impact breccia

A preliminary paleomagnetic study of the impact breccia matrix and clasts has produced surprising results--nearly antipodal normal and reversed polarity magnetic vectors are observed in different portions of the core. Near-antipodal magnetizations within a segment of matrix and within individual samples rule out core inversion as the explanation of the dual polarity. In both the dense and the sandy matrix breccias, the magnetizations of clasts and matrix within the same core segment are identical; this negative 'conglomerate test' indicates that magnetization originated after impact. Paleomagnetic study of the Manson Impact Structure is an attempt to refine the Ar-40/Ar-39 age (65.7 +/- 1 m.y.) that suggests Manson to be a Cretaceous-Tertiary boundary impact. Refinement is possible because the boundary occurs within a reversed polarity interval (29R) of only 0.5 m.y. duration. The two breccia types in the Manson structure were both examined: one of a very dense matrix and apparently partially melted, and the breccia stratigraphically below it of granular or 'sandy' chloritic matrix. Samples were taken from the matrixes and a wide variety of clast compositions, including granite, diabase, gneiss, amphibolite, and melted granite. Currently, measurements have been made on 22 samples, using 30-35 steps of either alternating field (AF) or thermal demagnetization.

Steiner, M. B.↗

Reduced Navier Stokes Relaxation Procedures for Internal Flows

In spite of significant advancement in the field of high speed computing, flow calculations involving complex geometries and/or flow behavior still require large amounts of CPU time and memory. In order to predict such flows without sacrificing grid convergence and accuracy, adaptive gridding techniques that provide optimal resolution are highly desirable. The present work combines multigrid techniques and domain decomposition concepts to provide local, solution adaptive, grid refinement. Several viscous compressible and incompressible, two and three-dimensional, flows with strong inviscid interaction and/or axial flow reversal, are considered with a segmented multigrid domain decomposition (SMGDD) procedure for which uniform meshes result in each domain. A pressure-based form of flux-vector splitting is applied to the Navier-Stokes equations, which are represented by an implicit lowest-order reduced Navier-Stokes (RNS) system and a purely diffusive, higher-order, deferred-corrector. A trapezoidal or box-like form of discretization insures that all mass conservation properties are satisfied at interfacial and outflow boundaries, even for this primitive-variable non-staggered grid computation. The SMGDD technique presented herein has previously been applied for incompressible two dimensional flows. The present work offers improvement in the gridding strategy, by allowing for disjoint subdomains that provide optimal resolution of disparate flow features. It also extends the SMGDD technique to three dimensional compressible flows. Laminar and turbulent flow in a backward facing step channel is considered; although the procedure is applicable to more severe geometries. The standard K-epsilon model is applied for turbulence closure. For Re greater than 400, differences between two-dimensional theory and experiment are resolved through a three dimensional simulation, which confirms the experimentally observed three dimensionality of the recirculation patterns on the upper and lower surfaces.

Rubin, Stanley G.↗

Recent Updates to the Arnold Mirror Modeler and Integration into the Evolving NASA Overall Design System for Large Space-Based Optical Systems

Since last year, a number of expanded capabilities have been added to the modeler. The support the integration with thermal modeling, the program can now produce simplified thermal models with the same geometric parameters as the more detailed dynamic and even more refined stress models. The local mesh refinement and mesh improvement tools have been expanded and more user friendly. The goal is to provide a means of evaluating both monolithic and segmented mirrors to the same level of fidelity and loading conditions at reasonable man-power efforts. The paper will demonstrate most of these new capabilities.

Large Space-based↗

Recent Updates to the Arnold Mirror Modeler and Integration into the Evolving NASA Overall Design System for Large Space Based Optical Systems

Since last year, a number of expanded capabilities have been added to the modeler. The support the integration with thermal modeling, the program can now produce simplified thermal models with the same geometric parameters as the more detailed dynamic and even more refined stress models. The local mesh refinement and mesh improvement tools have been expanded and more user friendly. The goal is to provide a means of evaluating both monolithic and segmented mirrors to the same level of fidelity and loading conditions at reasonable man-power efforts. The paper will demonstrate most of these new capabilities.

Arnold, William R., Sr.↗

Data-driven Mapping of the Mouse Connectome: The utility of transfer learning to improve the performance of deep learning models performing axon segmentation on light-sheet microscopy images

Light sheet microscopy has made possible the high temporal and spatial 3D imaging of both fixed and live biological tissue, with samples as large as the entire mouse brain. However, segmentation and quantification of that data remains a time-consuming manual process. Machine learning methods promise the possibility of automating this process. This study seeks to advance the performance of prior models through the application of refinements such as transfer learning.

59 BASIC BIOLOGICAL SCIENCES↗

Advanced Signal Processing Methods Applied to Digital Mammography

The work reported here is on the extension of the earlier proposal of the same title, August 1994-June 1996. The report for that work is also being submitted. The work reported there forms the foundation for this work from January 1997 to September 1997. After the earlier work was completed there were a few items that needed to be completed prior to submission of a new and more comprehensive proposal for further research. Those tasks have been completed and two new proposals have been submitted, one to NASA, and one to Health & Human Services WS). The main purpose of this extension was to refine some of the techniques that lead to automatic large scale evaluation of full mammograms. Progress on each of the proposed tasks follows. Task 1: A multiresolution segmentation of background from breast has been developed and tested. The method is based on the different noise characteristics of the two different fields. The breast field has more power in the lower octaves and the off-breast field behaves similar to a wideband process, where more power is in the high frequency octaves. After the two fields are separated by lowpass filtering, a region labeling routine is used to find the largest contiguous region, the breast. Task 2: A wavelet expansion that can decompose the image without zero padding has been developed. The method preserves all properties of the power-of-two wavelet transform and does not add appreciably to computation time or storage. This work is essential for analysis of the full mammogram, as opposed to selecting sections from the full mammogram. Task 3: A clustering method has been developed based on a simple counting mechanism. No ROC analysis has been performed (and was not proposed), so we cannot finally evaluate this work without further support. Task 4: Further testing of the filter reveals that different wavelet bases do yield slightly different qualitative results. We cannot provide quantitative conclusions about this for all possible bases without further support. Task 5: Better modeling does indeed make an improvement in the detection output. After the proposal ended, we came up with some new theoretical explanations that helps in understanding when the D4 filter should be better. This work is currently in the review process. Task 6: N/A. This no longer applies in view of Tasks 4-5. Task 7: Comprehensive plans for further work have been completed. These plans are the subject of two proposals, one to NASA and one to HHS. These proposals represent plans for a complete evaluation of the methods for identifying normal mammograms, augmented with significant further theoretical work.

Stauduhar, Richard P.↗

Correlation functions on the Half-BPS Wilson loop: perturbation and hexagonalization

We compute correlation functions of protected primaries on the 1/2-BPS Wilson loop in N=4 super Yang-Mills theory at weak coupling. We first perform direct perturbative computation at one loop in the planar limit and present explicit formulae for general two-, three- and four-point functions. The results for two- and three-point functions as well as four-point functions in special kinematics are in perfect agreement with the localization computation performed in arXiv:1802.05201 . We then analyze the results in view of the integrability-based approach called “hexagonalization”, which was introduced previously to study the correlation functions in the absence of the Wilson loop. In this approach, one decomposes the correlator into fundamental building blocks called “hexagons”, and glues them back together by summing over the intermediate states. Through the comparison, we conjecture that the correlation functions on the Wilson loop can be computed by contracting hexagons with boundary states, where each boundary state represents a segment of the Wilson loop. As a byproduct, we make predictions for the large-charge asymptotics of the structure constants on the Wilson loop. Along the way, we refine the conjecture for the integrability-based approach to the general non-BPS structure constants on the Wilson loop, proposed originally in arXiv:1706.02989 .

1/N Expansion↗