Search NASA⌕ Search

SEARCH · Search NASA

Results for “similarity”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 73 records · Page 4
All sourcesNASA NTRSDOE OSTI
DOE OSTI2025

Towards Automatically Matching Security Advisories to CPEs: String Similarity-based Vendor Matching

When a vulnerability is reported by the National Vulnerability Database (NVD), affected products are listed in the structured Common Platform Enumeration (CPE) format. Unfortunately, if the vulnerability is in a software library (e.g., Log4j), it will not include CPEs for each product containing that library. In these cases, security operators need to manually read the vendor's or third-party security advisories to see if their product is affected. However, these advisories do not report affected products in a structured format, which prevents automated processing, This paper makes the first effort towards automatically constructing structured CPEs for the vulnerable products in a non-NVD security advisory from the unstructured data in the advisory. Since this is a very challenging problem, this paper specifically focuses on the initial but key step of matching the un-structured vendor names in security advisories to the structured vendor representations in the standard CPE format. We explore the feasibility of using string similarity to solve the problem. The basic idea is to compare a vendor name from the non-NVD advisory with each vendor in the official CPE dictionary. The CPE vendor with the highest similarity score to the advisory's vendor will be considered as the match. We first conduct an experimental, comparative study of multiple mainstream string similarity metrics for this matching problem. To improve the performance, we then design a new string similarity metric that is adapted from an existing metric by weighing different tokens in the advisory's vendor name differently.

McClanahan, Kylie↗
DOE OSTI2020

Crystal Structure and Characterization of Human Heavy-Chain Only Antibodies Reveals a Novel, Stable Dimeric Structure Similar to Monoclonal Antibodies

We report the novel crystal structure and characterization of symmetrical, homodimeric humanized heavy-chain-only antibodies or dimers (HC2s). HC2s were found to be significantly coexpressed and secreted along with mAbs from transient CHO HC/LC cotransfection, resulting in an unacceptable mAb developability attribute. Expression of full-length HC2s in the absence of LC followed by purification resulted in HC2s with high purity and thermal stability similar to conventional mAbs. The V H and C H 1 portion of the heavy chain (or Fd) was also efficiently expressed and yielded a stable, covalent, and reducible dimer (Fd2). Mutagenesis of all heavy chain cysteines involved in disulfide bond formation revealed that Fd2 intermolecular disulfide formation was similar to Fabs and elucidated requirements for Fd2 folding and expression. For one HC2, we solved the crystal structure of the Fd2 domain to 2.9 Å, revealing a highly symmetrical homodimer that is structurally similar to Fabs and is mediated by conserved (C H 1) and variable (V H ) contacts with all CDRs positioned outward for target binding. Interfacial dimer contacts revealed by the crystal structure were mutated for two HC2s and were found to dramatically affect HC2 formation while maintaining mAb bioactivity, offering a potential means to modulate novel HC2 formation through engineering. These findings indicate that human heavy-chain dimers can be secreted efficiently in the absence of light chains, may show good physicochemical properties and stability, are structurally similar to Fabs, offer insights into their mechanism of formation, and may be amenable as a novel therapeutic modality.

60 APPLIED LIFE SCIENCES↗
DOE OSTI2024

Using Hydrodynamic Similarity as a Verification Method for Impact Cratering Simulations in the FLAG Hydrocode

Hydrodynamic codes (hydrocodes) are common tools for modeling hypervelocity impacts to provide insight into the physical phenomenon. Hydrocodes can simulate impacts from micrometer to kilometer spatial scales and reach impact velocities difficult to achieve in experimental settings. However, numerical models are approximations, and demonstrating that a numerical method is capable of providing physical results for these models is essential. In this work, we employ a hydrocode verification technique that leverages hydrodynamic similarity, a mathematical property of the conservation equations of fluid mechanics that form the basis for hydrocode models. Using the FLAG hydrocode, we simulate aluminum (Al) and basalt projectiles and targets at spatial scales spanning 7 orders of magnitude (hundreds of micrometers to kilometers). These materials were chosen because Al-6061 is a common material in spacecraft and satellites and basalt is a useful approximation of rocky astronomical bodies. Our results show that hydrodynamic similarity holds for each material model used and across spatial scales. We show that under certain conditions hydrodynamic similarity can apply in the presence of gravity and that similarity does not hold in the presence of strength models. We conclude that the FLAG hydrocode preserves important mathematical properties of fluid dynamics in hypervelocity impacts of Al-6061 and basalt.

79 ASTRONOMY AND ASTROPHYSICS↗
NASA NTRS1976

Similarity theory of the buoyantly interactive planetary boundary layer with entrainment

A similarity model is developed for the vertical profiles of turbulent flow variables in an entraining turbulent boundary layer of arbitrary buoyant stability. In the general formulation the vertical profiles, internal rotation of the velocity vector, discontinuities or jumps at a capping inversion and bulk aerodynamic coefficients of the boundary layer are given by solutions to a system of ordinary differential equations in the similarity variable. To close the system, a formulation for buoyantly interactive eddy diffusivity in the boundary layer is introduced which recovers Monin-Obukhov similarity near the surface and incorporates a hypothesis accounting for the observed variation of mixing length throughout the boundary layer. The model is tested in simplified versions which depend only on roughness, surface buoyancy, and Coriolis effects by comparison with planetary-boundary-layer wind- and temperature-profile observations, measurements of flat-plate boundary layers in a thermally stratified wind tunnel and observations of profiles of terms in the turbulent kinetic-energy budget of convective planetary boundary layers. On balance, the simplified model reproduced the trend of these various observations and experiments reasonably well, suggesting that the full similarity formulation be pursued further.

Hoffert, M. I.↗
NASA NTRS1979

Application of the principle of similarity fluid mechanics

Possible applications of the principle of similarity to fluid mechanics is described and illustrated. In correlating thermophysical properties of fluids, the similarity principle transcends the traditional corresponding states principle. In fluid mechanics the similarity principle is useful in correlating flow processes that can be modeled adequately with one independent variable (i.e., one-dimensional flows). In this paper we explore the concept of transforming the conservation equations by combining similarity principles for thermophysical properties with those for fluid flow. We illustrate the usefulness of the procedure by applying such a transformation to calculate two phase critical mass flow through a nozzle.

Hendricks, R. C.↗
NASA NTRS1984

Eigenvalue similarity rules for symmetric cross-ply laminated plates

Symmetric cross-ply laminated plates are analyzed by employing a previously presented affine stretching process, some material constant definitions from Tsai (1964), and by gneralizing existing similarity rules. As examples, similarity rules are employed to find the frequency spectrum of a cross-ply symmetric plate from the corresponding isotropic solution, and a similarity solution is presented for the vibration of an axially loaded, simply supported cross-ply symmetric plate. Buckling similarity rules are also presented.

Brunelle, E. J.↗
NASA NTRS1987

Engineering analysis of slender-body aerodynamics using Sychev similarity parameters

The similarity parameters deduced by Sychev for inviscid hypersonic flow over slender bodies are reviewed and used to correlate flowfield, surface-pressure, normal-force and center-of-pressure data for supersonic flow over thin slender wings and smooth slender bodies at low-to-high angles of attack. Although Sychev expected similarity to hold only for hypersonic freestream and cross flows, it is demonstrated empirically that similarity holds for any value of cross-flow Mach number if the axial flow component is supersonic. It is also shown for thin wings that similarity holds for much larger values of aspect ratio than Sychev supposed. A one-term power-law expression is found to fit all of the normal-force correlations which suggests that it may be possible to develop a simple semi-empirical method for estimating the aerodynamic characteristics of arbitrary slender airframes.

Hemsch, Michael J.↗
NASA NTRS1987

Similarity networks as a knowledge representation for space applications

Similarity networks are a powerful form of knowledge representation that are useful for many artificial intelligence applications. Similarity networks are used in applications ranging from information analysis and case based reasoning to machine learning and linking symbolic to neural processing. Strengths of similarity networks include simple construction, intuitive object storage, and flexible retrieval techniques that facilitate inferencing. Therefore, similarity networks provide great potential for space applications.

Bailey, David↗
NASA NTRS1987

On self-similarity of crack layer

The crack layer (CL) theory of Chudnovsky (1986), based on principles of thermodynamics of irreversible processes, employs a crucial hypothesis of self-similarity. The self-similarity hypothesis states that the value of the damage density at a point x of the active zone at a time t coincides with that at the corresponding point in the initial (t = 0) configuration of the active zone, the correspondence being given by a time-dependent affine transformation of the space variables. In this paper, the implications of the self-similarity hypothesis for qusi-static CL propagation is investigated using polystyrene as a model material and examining the evolution of damage distribution along the trailing edge which is approximated by a straight segment perpendicular to the crack path. The results support the self-similarity hypothesis adopted by the CL theory.

Botsis, J.↗
NASA NTRS1988

Isothermal magnetostatic atmospheres. II - Similarity solutions with current proportional to the magnetic potential cubed

The paper presents a family of isothermal magnetostatic atmospheres with one ignorable coordinate corresponding to a uniform gravitational field in a plane geometry. The distributed current in the model J is directed along the x-axis, where x is the horizontal ignorable coordinate. The current J is taken to be proportional to the cube of the magnetostatic potential A and falls off exponentially with distance vertical to the base with an e-folding distance equal to the gravitational scale height. A range of similarity solution examples are displayed depending on the values of the similarity parameters. Each similarity parameter corresponds to a symmetry of the underlying nonlinear elliptic equation for A. The similarity parameters also determine the source currents for the potential field solution of the family. The solutions show the interplay between the gravitational force, the J & B force (B, magnetic field induction) and the gas pressure gradient.

Webb, G. M.↗
NASA NTRS1992

Self-similar evolution of magnetized plasmas. I - Quasi-static solution

The concept of linear expansion suggested by Wei-Hong (1989 and 1990), describes the self-similar evolution of a magnetic structure. Linear expansion can be represented by a single function which connects the evolving physical parameters of the plasma with their initial values in explicit forms. A general self-similar dynamic equation, therefore, is derived. As the first step toward more general consideration, the quasi-static solution is investigated in this paper. It is shown that a gamma = 4/3 polytrope may evolve through consecutive equilibria if its magnetic field expands self-similarly. The change of the energy everywhere inside the plasma equals the work done by the internal plasma pressure and magnetic field for the expansion. For the special case of an expanding force-free magnetic field, the self-similar expansion is a clean expansion. No free magnetic energy is left anywhere inside the magnetic structure. The approximation in quasi-state modeling of a pressure confined magnetized plasmoid is analyzed.

Yang, Wei-Hong↗
NASA NTRS1950

An Analysis of the Applicability of the Hypersonic Similarity Law to the Study of Flow About Bodies of Revolution at Zero Angle of Attack

The hypersonic similarity law as derived by Tsien has been investigated by comparing the pressure distributions along bodies of revolution at zero angle of attack. In making these comparisons, particular attention was given to determining the limits of Mach number and fineness ratio for which the similarity law applies. For the purpose of this investigation, pressure distributions determined by the method of characteristics for ogive cylinders for values of Mach numbers and fineness ratios varying from 1.5 to 12 were compared. Pressures on various cones and on cone cylinders were also compared in this study. The pressure distributions presented demonstrate that the hypersonic similarity law is applicable over a wider range of values of Mach numbers and fineness ratios than might be expected from the assumptions made in the derivation. This is significant since within the range of applicability of the law a single pressure distribution exists for all similarly shaped bodies for which the ratio of free-stream Mach number to fineness ratio is constant. Charts are presented for rapid determination of pressure distributions over ogive cylinders for any combination of Mach number and fineness ratio within defined limits.

PRESSURE DISTRIBUTION - BODIES OF REVOLUTION↗
NASA NTRS2019

Fermi-GBM GRBs with Characteristics Similar to GRB 170817A

We present a search for gamma-ray bursts in the Fermi-GBM (Gamma Burst Monitor) 10-year catalog that show similar characteristics to GRB170817A, the first electromagnetic counterpart to a GRB (Gamma-Ray Burst) identified as a binary neutron star (BNS) merger via gravitational wave observations. Our search is focused on a nonthermal pulse, followed by a thermal component,as observed for GRB 170817A. We employ search methods based on the measured catalog parameters and Bayesian Block analysis. Our multipronged approach, which includes examination of the localization and spectral properties of the thermal component, yields a total of 13 candidates, including GRB170817A and the previously reported similar burst, GRB 150101B. The similarity of the candidates is likely caused by the same processes that shaped the gamma-ray signal of GRB170817A, thus providing evidence of a nearby sample of short GRBs resulting from BNS merger events. Some of the newly identified counterparts were observed by other space telescopes and ground observatories, but none of them have a measured redshift. We present an analysis of this subsample, and we discuss two models. From uncovering 13 candidates during a time period of 10 years we predict that Fermi-GBM will trigger on-board on about one burst similar to GRB170817A per year.

von Kienlin, A.↗
NASA NTRSDate not supplied

Evaluation of Preliminary Buffet Forcing Function Development based on Wind-Tunnel Tests of Geometrically-similar Models

The current state-of-the-art for launch vehicle buffet load estimation involves wind tunnel testing of highly instrumented rigid models and data processing of experimental unsteady pressure measurements to estimate the fluctuating aerodynamic loads. The model and instrumentation requirements to accomplish this type of testing are significant. The rigid model, in particular, must be built with relatively high geometric fidelity to approximate similar aerodynamic phenomena that will occur during the full-scale vehicle flight. Due to this requirement, several iterative wind tunnel tests are often required during the design maturation of the vehicle. For preliminary buffet load estimation, however, data from previous launch vehicle wind tunnel tests of geometrically similar models can be used to provide initial buffet environment estimates before a high geometric fidelity wind tunnel test has been conducted. In this paper, two components of this preliminary buffet estimation process are described: (1) assembly of buffet forcing functions from multiple data sources and (2) scaling of these buffet forcing functions to geometrically-similar components of a target vehicle configuration. The impacts of these estimation methods on the full-vehicle buffet forcing functions, including their longitudinal distribution along the vehicle, frequency-content at individual stations, and station-to-station coherence, are investigated. Considerations for using these methods to extrapolate wind tunnel data to geometrically similar models are also discussed.

Patrick S Heaney↗
NASA NTRSDate not supplied

Principles of Fluid Dynamic Similarity Analysis for Slosh Experiments

Most tank slosh test programs are not conducted with flight hardware in a flight-like environment due to cost and schedule constraints. Instead, subscale tanks are typically tested on the ground. If the “real”, flight liquid in the tank is a cryogenic propellant, sometimes a cryogen is used during testing, but more often a simulant liquid is used. Fluid dynamic similarity analysis, or “scaling analysis” as it is sometimes called, for slosh examines nondimensional numbers to determine which fluid dynamic regime(s) a tank is operating in. If the relevant nondimensional numbers of a scale tank test are similar enough to the real tank’s nondimensional numbers, then it is likely that the scale test data will be similar to what would be obtained with the real tank. This type of analysis is useful for guiding experiment design, test liquid selection, and for understanding the physical relevance of prior test data to a specific application. The authors have performed scaling analyses for many slosh test programs conducted in ground, parabolic flight, suborbital, and in-orbit environments. Basics of how to perform the analysis, along with select examples from ground and microgravity environments, are presented. Suggestions for various assumptions and compromises to make are discussed. Limitations and challenges are also discussed.

slosh↗
DOE OSTI2022

Model‐Based Approach to Selecting Pegfilgrastim Dose for Pharmacokinetic and Pharmacodynamic Similarity Studies in Biosimilar Development

This study applied modeling and simulation (M&S) approaches to evaluate the sensitivity of pegfilgrastim pharmacokinetics (PKs) and pharmacodynamics (PDs) to changes in dose amount, and linear or nonlinear clearance (CL) over pegfilgrastim subcutaneous dose of 2–6 mg. A previously published model was adapted to better describe pegfilgrastim PK and PD data in healthy subjects and used in simulation. Nonlinear CL accounts for 98% and 77%, respectively, of the total CL of pegfilgrastim at 2 and 6 mg. The sensitivity analyses showed: (i) PK of 2 and 6 mg doses are similarly sensitive to detect differences for a 5% change in dose; (ii) PK of 2 mg dose is more sensitive to changes in receptor binding affinity, a model parameter for nonlinear CL, and a product quality attribute characterized with orthogonal methods as part of demonstrating analytical similarity between products; (iii) PK of approved 6 mg dose is more sensitive to changes in linear CL, which has not been associated with any specific product quality attributes, and (iv) the PDs are not sensitive to changes in linear or nonlinear CL. Taken together, our analyses support that the approved pegfilgrastim dose of 6 mg is appropriate for detecting differences between a biosimilar and the reference products in pegfilgrastim PK and PD similarity studies. The described M&S approaches can be adopted to support dose selection for biosimilars with nonlinear PK and complex PK–PD interplay.

Pharmacology & Pharmacy↗
DOE OSTI2023

Scaling CFB risers: Beyond the data using microstructure similarity

Scaling circulating fluidized bed risers has been a point of contention for nearly a century. There have been numerous attempts to define various methodologies. These have all fallen short of providing a robust approach, primarily due to a lack of maintaining microstructure dynamics – a key factor in maintaining interphase heat and mass transfer. Recent work by the author put forward an approach based upon preserving dynamic similarity at different scales by ensuring that the microstructure remained similar by maintaining statistical and chaotic parameters across the scale. That work relied on a dimensionless regime map in which the x-axis was defined by the ratio of the solids flux to the saturation carrying capacity. This latter property was only good within the range of the data, and it became evident that extrapolation beyond the limits of the data could induce unrealistic conditions. Therefore, literature was reviewed to develop a better correlation for the saturation carrying capacity. In doing so, a critical riser diameter concept was developed and applied to the correlations for both Geldart Group A and B materials. The critical diameter for Geldart Group A and B materials is 0.2 m and 0.3 m, respectively. Here the paper then gives three examples on how to use the scaling approach to maintain dynamic similarity across the scales.

02 PETROLEUM↗
DOE OSTI2023

BLINK enables ultrafast tandem mass spectrometry cosine similarity scoring

Metabolomics has a long history of using cosine similarity to match experimental tandem mass spectra to databases for compound identification. Here we introduce the Blur-and-Link (BLINK) approach for scoring cosine similarity. By bypassing fragment alignment and simultaneously scoring all pairs of spectra using sparse matrix operations, BLINK is over 3000 times faster than MatchMS, a widely used loop-based alignment and scoring implementation. Using a similarity cutoff of 0.7, BLINK and MatchMS had practically equivalent identification agreement, and greater than 99% of their scores and matching ion counts were identical. This performance improvement can enable calculations to be performed that would typically be limited by time and available computational resources.

47 OTHER INSTRUMENTATION↗