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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 757 records · Page 42

Left ventricular, systemic arterial, and baroreflex responses to ketamine and TEE in chronically instrumented monkeys

Effects of prescribed doses of ketamine five minutes after application and influences of transesophageal echocardiography (TEE) on left ventricular, systemic arterial, and baroreflex responses were investigated to test the hypothesis that ketamine and/or TEE probe insertion alter cardiovascular function. Seven rhesus monkeys were tested under each of four randomly selected experimental conditions: (1) intravenous bolus dose of ketamine (0.5 ml), (2) continuous infusion of ketamine (500 mg/kg/min), (3) continuous infusion of ketamine (500 mg/kg/min) with TEE, and (4) control (no ketamine or TEE). Monkeys were chronically instrumented with a high fidelity, dual-sensor micromanometer to measure left ventricular and aortic pressure and a transit-time ultrasound probe to measure aortic flow. These measures were used to calculate left ventricular function. A 4-element Windkessel lumped-parameter model was used to estimate total peripheral resistance and systemic arterial compliance. Baroreflex response was calculated as the change in R-R interval divided by the change in mean aortic pressure measured during administration of graded concentrations of nitroprusside. The results indicated that five minutes after ketamine application heart rate and left ventricular diastolic compliance decreased while TEE increased aortic systolic and diastolic pressure. We conclude that ketamine may be administered as either a bolus or continuous infusion without affecting cardiovascular function 5 minutes after application while the insertion of a TEE probe will increase aortic pressure. The results for both ketamine and TEE illustrate the classic "Hawthorne Effect," where the observed values are partly a function of the measurement process. Measures of aortic pressure, heart rate, and left ventricular diastolic pressure should be viewed as relative, as opposed to absolute, when organisms are sedated with ketamine or instrumented with a TEE probe.

Non-NASA Center↗

Development of a Probabilistic Dynamic Synthesis Method for the Analysis of Nondeterministic Structures

Accounting for the statistical geometric and material variability of structures in analysis has been a topic of considerable research for the last 30 years. The determination of quantifiable measures of statistical probability of a desired response variable, such as natural frequency, maximum displacement, or stress, to replace experience-based "safety factors" has been a primary goal of these studies. There are, however, several problems associated with their satisfactory application to realistic structures, such as bladed disks in turbomachinery. These include the accurate definition of the input random variables (rv's), the large size of the finite element models frequently used to simulate these structures, which makes even a single deterministic analysis expensive, and accurate generation of the cumulative distribution function (CDF) necessary to obtain the probability of the desired response variables. The research presented here applies a methodology called probabilistic dynamic synthesis (PDS) to solve these problems. The PDS method uses dynamic characteristics of substructures measured from modal test as the input rv's, rather than "primitive" rv's such as material or geometric uncertainties. These dynamic characteristics, which are the free-free eigenvalues, eigenvectors, and residual flexibility (RF), are readily measured and for many substructures, a reasonable sample set of these measurements can be obtained. The statistics for these rv's accurately account for the entire random character of the substructure. Using the RF method of component mode synthesis, these dynamic characteristics are used to generate reduced-size sample models of the substructures, which are then coupled to form system models. These sample models are used to obtain the CDF of the response variable by either applying Monte Carlo simulation or by generating data points for use in the response surface reliability method, which can perform the probabilistic analysis with an order of magnitude less computational effort. Both free- and forced-response analyses have been performed, and the results indicate that, while there is considerable room for improvement, the method produces usable and more representative solutions for the design of realistic structures with a substantial savings in computer time.

Brown, A. M.↗

Aircraft en route noise annoyance

Results are reported from a laboratory experiment conducted in order to quantify the annoyance experienced by people on the ground in response to en route noise (ERN) generated by aircraft at cruise conditions. Objectives included the comparison of annoyance responses to ERN with the annoyance responses to takeoff and landing noise; the comparison of the annoyance responses to advanced turboprop aircraft ERN with those of the turbofan ERN; and also the ability of aircraft noise measurement procedures and corrections to predict annoyance to ERN. Tests were conducted at the Langley Acoustics Research Laboratory on 32 human subjects selected at random. Subjects judged the annoyance level of 24 Propfan Test Assessment advanced turboprop ERN stimuli, 18 conventional turbofan ERN stimuli, and 60 conventional turboprop and turbofan takeoff and landing noise stimuli. Analysis of resulting data compared annoyance responses to different aircraft types and operations, examined the ability of current noise measurement and correction procedures to predict annoyance ERN, and calculated optimum duration correction magnitudes for ERN.

Mccurdy, David A.↗

An application of survival analysis to disruption prediction via Random Forests

One of the most pressing challenges facing the fusion community is adequately mitigating or, even better, avoiding disruptions of tokamak plasmas. However, before this can be done, disruptions must first be predicted with sufficient warning time to actuate a response. The established field of survival analysis provides a convenient statistical framework for time-to-event (i.e. time-to-disruption) studies. This paper demonstrates the integration of an existing disruption prediction machine learning algorithm with the Kaplan-Meier estimator of survival probability. Specifically discussed are the implied warning times from binary classification of disruption databases and the interpretation of output signals from Random Forest algorithms trained and tested on these databases. This survival analysis approach is applied to both smooth and noisy test data to highlight important features of the survival and hazard functions. In addition, this method is applied to three Alcator C-Mod plasma discharges and compared to a threshold-based scheme for triggering alarms. In one case, both techniques successfully predict the disruption; although, in another, neither warns of the impending disruption with enough time to mitigate. For the final discharge, the survival analysis approach could avoid the false alarm triggered by the threshold method. Limitations of this analysis and opportunities for future work are also presented.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Structure Tuning, Strong Second Harmonic Generation Response, and High Optical Stability of the Polar Semiconductors Na 1- x K x AsQ 2

We report the mixed cation compounds Na 1-x K x AsSe 2 (x = 0.8, 0.65, 0.5) and Na 0.1 K 0.9 AsS 2 crystallize in the polar noncentrosymmetric space group Cc. The AAsQ(2) (A = alkali metals, Q = S, Se) family features one-dimensional (1D) 1 / ∞ [AQ 2 - ] chains comprising corner-sharing pyramidal AQ 3 units in which the packing of these chains is dependent on the alkali metals. The parallel 1 / ∞ [AQ(2) - ] chains interact via short As ∙∙∙Se contacts, which increase in length when the fraction of K atoms is increased. The increase in the As ∙∙∙Se interchain distance increases the band gap from 1.75 eV in γ-NaAsSe 2 to 2.01 eV in Na 0.35 K 0.65 AsSe 2 , 2.07 eV in Na 0.2 K 0.8 AsSe 2 , and 2.18 eV in Na 0.1 K 0.9 AsS 2 . The Na 1-x K x AsSe 2 (x = 0.8, 0.65) compounds melt congruently at approximately 316 °C. Wavelength-dependent second harmonic generation (SHG) measurements on powder samples of Na 1-x K x AsSe 2 (x = 0.8, 0.65, 0.5) and Na 0.1 K 0.9 AsS 2 suggest that Na 0.2 K 0.8 AsSe 2 and Na 0.1 K 0.9 AsS 2 have the highest SHG response and exhibit significantly higher laser-induced damage thresholds (LIDTs). Theoretical SHG calculations on Na 0.5 K 0.5 AsSe 2 confirm its SHG response with the highest value of d 33 = 22.5 pm/V χ 333 (2) = 45.0 pm/V). The effective nonlinearity for a randomly oriented powder is calculated to be d eff = 18.9 pm/V χ eff (2) = 37.8 pm/V), which is consistent with the experimentally obtained value of d eff = 16.5 pm/V χ eff (2) = 33.0 pm/V). Three-photon absorption is the dominant mechanism for the optical breakdown of the compounds under intense excitation at 1580 nm, with Na 0.2 K 0.8 AsSe 2 exhibiting the highest stability.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Learning local, quenched disorder in plasticity and other crackling noise phenomena

Abstract When far from equilibrium, many-body systems display behavior that strongly depends on the initial conditions. A characteristic such example is the phenomenon of plasticity of crystalline and amorphous materials that strongly depends on the material history. In plasticity modeling, the history is captured by a quenched, local and disordered flow stress distribution. While it is this disorder that causes avalanches that are commonly observed during nanoscale plastic deformation, the functional form and scaling properties have remained elusive. In this paper, a generic formalism is developed for deriving local disorder distributions from field-response (e.g., stress/strain) timeseries in models of crackling noise. We demonstrate the efficiency of the method in the hysteretic random-field Ising model and also, models of elastic interface depinning that have been used to model crystalline and amorphous plasticity. We show that the capacity to resolve the quenched disorder distribution improves with the temporal resolution and number of samples.

36 MATERIALS SCIENCE↗

3D-Printing of Meso-structurally Ordered Carbon Fiber/Polymer Composites with Unprecedented Orthotropic Physical Properties

Here we report the first example of a class of additively manufactured carbon fiber reinforced composite (AMCFRC) materials which have been achieved through the use of a latent thermal cured aromatic thermoset resin system, through an adaptation of direct ink writing (DIW) 3D-printing technology. We have developed a means of printing high performance thermoset carbon fiber composites, which allow the fiber component of a resin and carbon fiber fluid to be aligned in three dimensions via controlled micro-extrusion and subsequently cured into complex geometries. Characterization of our composite systems clearly show that we achieved a high order of fiber alignment within the composite microstructure, which in turn allows these materials to outperform equivalently filled randomly oriented carbon fiber and polymer composites. Moreover, our AM carbon fiber composite systems exhibit highly orthotropic mechanical and electrical responses as a direct result of the alignment of carbon fiber bundles in the microscale which we predict will ultimately lead to the design of truly tailorable carbon fiber/polymer hybrid materials having locally programmable complex electrical, thermal and mechanical response.

36 MATERIALS SCIENCE↗

How can a diverse set of integral and semi-integral measurements inform identification of discrepant nuclear data?

Nuclear data are used for a variety of applications, including criticality safety, reactor performance, and material safeguards. Despite the breadth of use-cases, the effective neutron multiplication factor, keff, of ICSBEP critical assemblies are primarily used for nuclear data validation; these are sensitive to specific energy regions and nuclides and are unable to uniquely constrain nuclear data. As a consequence, general-purpose nuclear data libraries, such as ENDF/B-VIII.0, may have deficiencies that, while not apparent in criticality applications, negatively impact other applications, such as non-destructive analysis of special nuclear material and neutron diagnosed subcritical experiments. Recent work by the Experiments Underpinned by Computational Learning for Improvements in Nuclear Data (EUCLID) project developed a machine learning tool, RAFIEKI, which uses random forests and the SHAP metric to determine which nuclear data contribute most to predicted bias between measured and simulated responses (e.g. keff). This paper contrasts RAFIEKI analysis applied to keff only against RAFIEKI analysis with keff paired with either LLNL pulsed sphere measurements or subcritical benchmarks. Two examples show that a) including pulsed sphere measurements substantially increases 9Be nuclear data importance to bias between 2 and 15 MeV, and b) including subcritical benchmarks has the potential for disentangling compensating errors between 240Pu (n,el) and (n,il) cross-sections between 0.1 and 10 MeV. These results show that RAFIEKI analysis applied to response sets that include, but go beyond, keff can aid nuclear data evaluators in identifying issues in nuclear data.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

Computational Model for Microballistic Perforation of Multilayer Graphene

The peridynamic theory of solid mechanics is applied to the continuum modeling of the impact of small, high-velocity silica spheres on multilayer graphene targets. The model treats the laminate as a brittle elastic membrane. The material model includes separate failure criteria for the initial rupture of the membrane and for propagating cracks. Material variability is incorporated by assigning random variations in elastic properties within Voronoi cells. The computational model is shown to reproduce the primary aspects of the response observed in experiments, including the growth of a family of radial cracks from the point of impact.

36 MATERIALS SCIENCE↗

Conservation of Species- and Trait-Based Modeling Network Interactions in Extremely Acidic Microbial Community Assembly

Understanding microbial interactions is essential to decipher the mechanisms of community assembly and their effects on ecosystem functioning, however, the conservation of species- and trait-based network interactions along environmental gradient remains largely unknown. Here, by using the network-based analyses with three paralleled data sets derived from 16S rRNA gene pyrosequencing, functional microarray, and predicted metagenome, we test our hypothesis that the network interactions of traits are more conserved than those of taxonomic measures, with significantly lower variation of network characteristics along the environmental gradient in acid mine drainage. The results showed that although the overall network characteristics remained similar, the structural variation was significantly lower at trait levels. The higher conserved individual node topological properties at trait level rather than at species level indicated that the responses of diverse traits remained relatively consistent even though different species played key roles under different environmental conditions. Additionally, the randomization tests revealed that it could not reject the null hypothesis that species-based correlations were random, while the tests suggested that correlation patterns of traits were non-random. Furthermore, relationships between trait-based network characteristics and environmental properties implied that trait-based networks might be more useful in reflecting the variation of ecosystem function. Taken together, our results suggest that deterministic trait-based community assembly results in greater conservation of network interaction, which may ensure ecosystem function across environmental regimes, emphasizing the potential importance of measuring the complexity and conservation of network interaction in evaluating the ecosystem stability and functioning.

59 BASIC BIOLOGICAL SCIENCES↗

Temporal regulation of cold transcriptional response in switchgrass

Switchgrass low-land ecotypes have significantly higher biomass but lower cold tolerance compared to up-land ecotypes. Understanding the molecular mechanisms underlying cold response, including the ones at transcriptional level, can contribute to improving tolerance of high-yield switchgrass under chilling and freezing environmental conditions. Here, by analyzing an existing switchgrass transcriptome dataset, the temporal cis- regulatory basis of switchgrass transcriptional response to cold is dissected computationally. We found that the number of cold-responsive genes and enriched Gene Ontology terms increased as duration of cold treatment increased from 30 min to 24 hours, suggesting an amplified response/cascading effect in cold-responsive gene expression. To identify genomic sequences likely important for regulating cold response, machine learning models predictive of cold response were established using k -mer sequences enriched in the genic and flanking regions of cold-responsive genes but not non-responsive genes. These k -mers, referred to as putative cis -regulatory elements (pCREs) are likely regulatory sequences of cold response in switchgrass. There are in total 655 pCREs where 54 are important in all cold treatment time points. Consistent with this, eight of 35 known cold-responsive CREs were similar to top-ranked pCREs in the models and only these eight were important for predicting temporal cold response. More importantly, most of the top-ranked pCREs were novel sequences in cold regulation. Our findings suggest additional sequence elements important for cold-responsive regulation previously not known that warrant further studies.

60 APPLIED LIFE SCIENCES↗

A Statistical Approach to Establishing Subsystem Environmental Test Specifications

Results are presented of a research task to evaluate structural responses at various subsystem mounting locations during spacecraft level test exposures to the environments of mechanical shock, acoustic noise, and random vibration. This statistical evaluation is presented in the form of recommended subsystem test specifications for these three environments as normalized to a reference set of spacecraft test levels and are thus suitable for extrapolation to a set of different spacecraft test levels. The recommendations are dependent upon a subsystem's mounting location in a spacecraft, and information is presented on how to determine this mounting zone for a given subsystem.

Keegan, W. B.↗

Optimal control of a low wing-loading STOL aircraft

Linear optimal quadratic control theory is applied to a low wing-loading STOL aircraft for ride quality and flight path following. Design criteria include minimum rms response to wind turbulence and desired transient response characteristics. Design techniques include proper choosing of design versus evaluation models, choosing appropriate performance index responses, and use of classical evaluation techniques. Results are obtained through a combination of frequency response shaping and gust observation. Effects of control rate and authority saturation are examined with a new rapid calculation of random input describing functions. Parameter sensitivity is also evaluated using a Liapunov type matrix equation.

Cunningham, T. B.↗

Bit error rate measurement above and below bit rate tracking threshold

Bit error rate is measured by sending a pseudo-random noise (PRN) code test signal simulating digital data through digital equipment to be tested. An incoming signal representing the response of the equipment being tested, together with any added noise, is received and tracked by being compared with a locally generated PRN code. Once the locally generated PRN code matches the incoming signal a tracking lock is obtained. The incoming signal is then integrated and compared bit-by-bit against the locally generated PRN code and differences between bits being compared are counted as bit errors.

Kobayaski, H. S.↗

Cockpit Window Edge Proximity Effects on Judgements of Horizon Vertical Displacement

To quantify the influence of a spatially fixed edge on vertical displacement threshold, twenty-four males (12 pilots, 12 non-pilots) were presented a series of forced choice, paired comparison trials in which a 32 deg arc wide, thin, luminous horizontal stimulus line moved smoothly downward through five angles from a common starting position within a three second-long period. The five angles were 1.4, 1.7, 2, 2.3, and 2.6 deg. Each angle was presented paired with itself and the other four angles in all combinations in random order. For each pair of trials the observer had to choose which trial possessed the largest displacement. A confidence response also was made. The independent variable was the angular separation between the lower edge of a stable 'window' aperture through which the stimulus was seen to move and the lowest position attained by the stimulus. It was found that vertical displacement accuracy is inversely related to the angle separating the stimulus and the fixed window edge (p = .05). In addition, there is a strong tendency for pilot confidence to be lower than that of non-pilots for each of the three angular separations. These results are discussed in erms of selected cockpit features and as they relate to how pilots judge changes in aircraft pitch attitude.

Haines, R. F.↗

Limits to the burster repetition rate as deduced from the 2nd catalog of the interplanetary network

The burster repetition rate is an important parameter in many gamma ray burst models. The localizations of the interplanetary network, which have a relatively small combined surface area, may be used to estimate the average repetition rate. The method consists of (1) estimating the number of random overlaps between error boxes expected in the catalog and comparing this number to that actually observed; (2) modeling the response of the detectors in the network, so that the probability of detecting a burst can be estimated; and (3) simulating the arrival of bursts at the network assuming that burster repetition is governed by a Poisson process. The application of this method for many different burster luminosity functions shows that (1) the lower limit to the burster repetition rate depends strongly upon the assumed luminosity function; (2) the best lower limit to the repetition period obtainable from the data of the network is about 100 months; and (3) that a luminosity function for all bursters similar to that of the 1979 Mar 5 burster is inconsistent with the data.

Atteia, J. L.↗

On the relationship between matched filter theory as applied to gust loads and phased design loads analysis

A theoretical basis and example calculations are given that demonstrate the relationship between the Matched Filter Theory approach to the calculation of time-correlated gust loads and Phased Design Load Analysis in common use in the aerospace industry. The relationship depends upon the duality between Matched Filter Theory and Random Process Theory and upon the fact that Random Process Theory is used in Phased Design Loads Analysis in determining an equiprobable loads design ellipse. Extensive background information describing the relevant points of Phased Design Loads Analysis, calculating time-correlated gust loads with Matched Filter Theory, and the duality between Matched Filter Theory and Random Process Theory is given. It is then shown that the time histories of two time-correlated gust load responses, determined using the Matched Filter Theory approach, can be plotted as parametric functions of time and that the resulting plot, when superposed upon the design ellipse corresponding to the two loads, is tangent to the ellipse. The question is raised of whether or not it is possible for a parametric load plot to extend outside the associated design ellipse. If it is possible, then the use of the equiprobable loads design ellipse will not be a conservative design practice in some circumstances.

Zeiler, Thomas A.↗

Radiative transfer theory for polarimetric remote sensing of pine forest

The radiative transfer theory is applied to interpret polarimetric radar backscatter from pine forest with clustered vegetation structures. The scattering function of each cluster is calculated by incorporating the phase interference of scattered fields from each component. The resulting phase matrix is used in the radiative transfer equations to evaluate the polarimetric backscattering coefficients from random medium layers embedded with vegetation clusters. Upon including multiscale structures (trunks, primary and secondary branches, and needles), polarimetric radar responses from pine forest for different frequencies and looking angles are interpreted and simulated. Preliminary results are shown to be in good agreement with the measured backscattering coefficients at the Landes maritime pine forest during the MAESTRO-1 experiment.

Hsu, C. C.↗