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At least 775 records · Page 43

Evidence for Increased Beta-Adrenoreceptor Responsiveness Induced by 14 Days of Simulated Microgravity in Humans

We studied hemodynamic responses to alpha and beta receptor agonists in 8 healthy men ( 38+- 2 yrs) before and after 14 days of 6 degree head-down tilt (HDT) to test the hypothesis that increased adrenergic responsiveness is induced by prolonged exposure to microgravity. Immediately following a 30-min baseline period, a steady-state infusion of isoproterenol (ISO) was used to assess beta 1- and beta 2-adrenergic responsiveness. ISO was infused at three graded constant rates of 0.005, 0.01 and 0.02 ug/kg/min. After heart rate and blood pressure had been allowed to return to baseline levels following ISO infusion graded infusion of phenylephrine (PE) was used to assess responsiveness of alpha I-vascular receptors. PE was infused at three graded constant rates of 0.25, 0.50 and 1.00 ug/kg/min. Each infusion interval for both drugs was 9 min. During the infusions, constant monitoring of beat-to-beat blood pressure and heart rate was performed and leg blood flow was measured with occlusion plethysmography at each infusion level. The slopes calculated from linear regressions between ISO and PE doses and changes in heart rate, blood pressure, and leg vascular resistance for each subject were used to represent alpha- and beta- adrenoreceptor responsiveness. Fourteen days HDT increased the slopes of heart rate (1056 +- 107 to 1553 +- 83 beats/ug/kg/min; P= 0.014) and vasodilation (-469ft +- 111 to -l446 +- 309 PRU/ug/kg/min; P =0.0224) to ISO infusion. There was no alteration in blood pressure or vascular resistance responses to PE infusion after HDT. Our results provide evidence that microgravity causes selective increases in beta 1- and beta 2-adrenergic responsiveness without affecting alpha 1-vascular responses.

CARDIOVASCULAR SYSTEM↗

Gas Exchange, Transpiration and Yield of Sweetpotato Grown in a Controlled Environment

Sweetpotato was grown to harvest maturity within NASA Johnson Space Center's Variable Pressure Growth Chamber (VPGC) to characterize crop performance for potential use in advanced life support systems as a contributor to food production, air revitalization and resource recovery. Stem cuttings of breeding clone "TU-82-155" were grown hydroponically at a density of 17 plants m(sup -2) using a modified pressure-plate growing system (Patent No. 4860-490, Tuskegee University). Lighting was provided by HPS lamps at a photoperiod of 12h light: 12h dark. The photosynthetic photon flux was maintained at 500, 750 and 1000 micro mol m(sup -2) s(sub -1) during days 1-15, 16-28, 29-119, respectively. Canopy temperatures were maintained at 28 C: light: 22 C:dark. During the light period, relative humidity and carbon dioxide were maintained at 70% and 1200 micro liters l(sup -1), respectively. Nutrient solution was manually adjusted 2 to 4 times per week by addition of 10X concentrated modified half-strength Hoagland nutrient salts and NaOH to return the electrical conductivity and pH to 1.2 mS cm(sup -1) and 6.0, respectively. At 17 weeks (119 days) from transplanting, a total of 56.5 kilograms fresh mass of storage roots (84.1% moisture) were harvested from the 11.2 m(sup 2) chamber, resulting in a yield 5.0 kilograms m(sup -2). Harvest index, based on fresh mass, was 38.6%. Rates of net photosynthesis, dark respiration, transpiration, and ethylene production will be reported.

Barta, Daniel J.↗

Trajectories for Flyby Sample Return at Saturn's Moons

Ballistic trajectories are computed which would enable a sample return mission to Titan or Enceladus without capturing, descending, or landing. The low-cost mission concept utilizes a free return trajectory that also involves a close flyby of the moon. This work extends the concept, and related trajectory analysis methodology, previously applied to a Europa mission. Specifically, a broad search algorithm is employed to systematically locate potentially feasible itineraries over an entire Saturn period. High-quality approximate solutions are then optimized to be continuous using high-fidelity dynamics. Techniques and software from the Europa analysis, were readily adapted and able to find numerous mission enabling trajectories. A direct mission to Titan is possible with flight time under 16 years and Earth-relative speeds below 11.0 km/sec. The VEEGA option is shown to substantially reduce launch C3, but flight times exceed 21 years. Unfortunately, an Enceladus mission requires a flight time of 25 years or more, and incurs fairly high relative speeds. Nevertheless, an optimized reference mission is computed.

Jones, Drew Ryan↗

Rapid Assessment of a Lunar Surface Laboratory Module

Johnson Space Center is piloting an innovation team known as the Forge to perform rapid turnaround, concurrent engineering studies. The Forge is intended to be able to pull together a team of strategically selected domain experts to innovatively solve a specified problem within a short period of time. The Forge’s inaugural project being the development of a Lunar Surface Laboratory Module concept. The lab module is intended as an option for the Artemis program’s Lunar Architecture Team. The lab module may allow for increased science productivity and return on investment than a surface architecture with only the habitat. This paper will discuss the configuration of the Lunar Laboratory module, including the pressure vessel, its placement relative to the Surface Habitat and Pressurized Rover, and internal architecture. In order to determine the suitability of such a design, a human factors evaluation is conducted. Historically, a human factors evaluation of a habitable volume could require a month or longer, including time needed to prepare a test plan, conduct the evaluation, compile the data, and produce a report. The entire Forge effort will only last for five weeks, forcing the creation of a rapid assessment process. This rapid assessment includes three evaluation studies, all conducted and processed in the space of a single day, to determine the acceptability of the resulting design. The first evaluation is a card sort evaluation of the laboratory instruments. A brief discussion of the card sort evaluation is provided. This card sort is focused on the relative positioning of the laboratory instruments, determining whether a given instrument should be adjacent to, or separated from, another. It will use human factors personnel and both life and physical scientists as subject matter experts. The second evaluation is a science productivity tabletop evaluation. This evaluation focuses on the selection of instruments and the number of instruments, attempting to assess the amount of work the crew will be able to use the facility to do. It uses life and physical science personnel as subject matter experts. The third evaluation is a CAD or Virtual Reality human factors walkthrough evaluation. This evaluation focuses on the layout of the lab module and its connectivity to the basecamp’s pressurized elements. If possible, astronauts will be used as subject matter experts. Each of these evaluations will focus primarily on objective data with limited subjective comments, reducing the time required for processing responses. The results of each evaluation and their implications will be discussed. Based on the evaluation data, an overall acceptability of the Lunar Surface Laboratory Module produced by the Forge study can be determined. Lessons learned and recommendations for future use of the human factors rapid assessment process in early design trades will also be provided.

Lunar Laboratory↗

Performance of a Surface Barrier for Waste Isolation and Flux Reduction at the Hanford Site

Based on the knowledge gained from a decade of laboratory, field, and numerical studies, the Prototype Hanford Barrier (PHB) was designed and constructed between late 1993 and late 1994 over the 216-B-57 Crib in the 200-BP-1 Operable Unit at the Hanford Site. The PHB has been monitored since 1994 to evaluate the physical, hydrologic, and ecological performance. Two stress tests were carried out in the past: (1) an enhanced (about 3 times the multi-year average of 160 mm/year) precipitation test from water year (WY) 1995 to WY1997, which included a man-made 1000-year return 24-hour rainstorms in March each year, and (2) a controlled fire test in 2008. The purpose of this article is to present the main findings of the PHB demonstration since 1994. From 1994 to present, the PHB has limited drainage of less than 0.2 mm yr-1, which is below the 0.5 mm yr-1 design goal, and minimized erosion. The observations suggest the PHB is robust enough to endure the hydrological stress of three times average precipitation and 1000-year return 24-hour rainstorms. After the controlled fire, far less vegetation grows and grasses are the dominant vegetation (compared to shrubs on the unburned section). Even so, the grasses can remove nearly all the stored water in the burned section, although during a longer period of time than in the unburned section. The findings at the PHB are useful for the design and monitoring of future surface barriers at Hanford and elsewhere.

ET Cover↗

Generation of Terawatt Attosecond Pulses from Relativistic Transition Radiation

When a femtosecond duration and hundreds of kiloampere peak current electron beam traverses the vacuum and high-density plasma interface, a new process, that we call here relativistic transition radiation (RTR), generates an intense ~ 100 as pulse containing ~ 1 terawatt power of coherent vacuum ultraviolet (VUV) radiation accompanied by several smaller femtosecond duration satellite pulses. This pulse inherits the radial polarization of the incident beam field and has a ring intensity distribution. This RTR is emitted when the beam density is comparable to the plasma density and the spot size much larger than the plasma skin depth. Physically, it arises from the return current or backward relativistic motion of electrons starting just inside the plasma that Doppler up shifts the emitted photons. The number of RTR pulses is determined by the number of groups of plasma electrons that originate at different depths within the first plasma wake period and emit coherently before phase mixing.

43 PARTICLE ACCELERATORS↗

PAIRS AND GROUPS OF GENETICALLY RELATED LONG-PERIOD COMETS AND PROPOSED IDENTITY OF THE MYSTERIOUS LICK OBJECT OF 1921

We present the history of investigation of the dynamical properties of pairs and groups of genetically related long-period comets (other than the Kreutz sungrazing system). Members of a comet pair or group move in nearly identical orbits, and their origin as fragments of a common parent comet is unquestionable. The only variable is the time of perihelion passage, which differs considerably from member to member owing primarily to an orbital-momentum increment acquired during breakup. Meter-per-second separation velocities account for gaps of years or tens of years, thanks to the orbital periods of many millennia. The physical properties of individual members may not at all be alike, as illustrated by the trio of C/1988 A1, C/1996 Q1, and C/2015 F3. We exploit orbital similarity to examine whether the enigmatic and as-yet-unidentified object discovered from the Lick Observatory near the Sun at sunset on 1921 August 7 happened to be a member of such a pair and to track down the long-period comet to which it might be genetically related. Our search shows that the Lick object, which could not be a Kreutz sungrazer, was likely a companion to comet C/1847 C1 (Hind), whose perihelion distance was ∼9 R {sub ⊙} and true orbital period was approximately 8300 yr. The gap of 74.4 yr between their perihelion times is consistent with a separation velocity of ∼1 m s{sup −1} which sets the fragments apart following the parent's breakup in a general proximity of perihelion during the previous return to the Sun in the seventh millennium BCE.

79 ASTRONOMY AND ASTROPHYSICS↗

Skylab hardware report operational bioinstrumentation system

The Skylab Operational Bioinstrumentation System is a personal, individually adjustable biomedical system designed to monitor the basic physiological functions of each suited crewman during specified periods of a manned space mission. The basic physiological functions of this system include electrocardiogram, respiration by impedance pneumogram, body temperature, cardiotachometer, and subject identification. The Operational Bioinstrumentation System was scheduled to monitor each crewman during launch, extravehicular activities, suited intravehicular experiments, and undocking and return.

Luczkowski, S.↗

The frequency of long-duration solar X-ray events

The rate of occurrence of coronal and interplanetary phenomena during the solar sunspot cycle was studied based on nearly continuous satellite data for long-duration events in the period 1969-1982. The data were obtained using the NRL SOLRAD and the NOAA GOES spacecraft for each year in the interval. The duration of the X-ray events was defined as the time for the logarithm of the 1-8 A flux to return to approximately 10 percent of the pre-event level. The total number of X-ray events is plotted next to the annual sunspot number for the interval 1969-1982. It is shown that the long duration of X-ray events was not related to the sunspot cycle, particularly events of 6 hr or more.

Koomen, M. J.↗

X-38 V201 Avionics Architecture

The X-38 is an experimental NASA project developing a core human capable spacecraft at a fraction of the cost of any previous human rated vehicle. The first operational derivative developed from the X-38 program will be the International Space Station (ISS) Crew Return Vehicle (CRV). Although the current X-38 vehicles are designed as re-entry vehicles only, the option exists to modify the vehicle for uses as an upward vehicle launched from an expendable launch vehicle or from the X-33 operational derivative. The Operational CRV, that will be derived from the X-38 spaceflight vehicle, will provide an emergency return capability from the International Space Station (ISS). The spacecraft can hold a crew of up to seven inside a pressurized cabin. The CRV is passively delivered to ISS, stays up to three year on-orbit attached to ISS in a passive mode with periodic functional checkout, before separation from ISS, de-orbit, entry and landing. The X-38 Vehicle 201 (V201) is being developed at NASA/JSC to demonstrate key technologies associated with the development of the CRV design. The X-38 flight test will validate the low cost development concept by demonstrating the entire station departure, re-entry, guidance and landing portions of the CRV mission. All new technologies and subsystems proposed for CRV will be validated during either the on orbit checkout or flight phases of the X-38 space flight test. The X-38 subsystems are required to be similar to those subsystems required for the CRV to the greatest extent possible. In many cases, the subsystems are identical to those that will be utilized on the Operational CRV.

Bedos, Thierry↗

Sampling Strategy and Curation Plan of "Hayabusa" Asteroid Sample Return Mission

On the 9th May 2003 JST, Japanese spacecraft MUSES-C was successfully launched from Uchinoura. The spacecraft was directly inserted to interplanetary trajectory and renamed as Hayabusa , or "Falcon" to be the world s first sample return spacecraft to a near Earth asteroid (NEA). The NEA (25143)Itokawa (formerly known as "1998SF36") is its mission target. Its orbital and physical characteristics were well observed; the size is (490 +/- 100)x (250 +/- 55)x(180 +/- 50) m with about 12-hour rotation period. It has a red-sloped S(IV)-type spectrum with strong 1- and 2-micron absorption bands, analogous to ordinary LL chondrites with space weathering effect. Assuming its bulk density, the surface gravity level of Itokawa is in the order of 10 micro-G with its escape velocity = approx. 20 cm/s.

Yano, H.↗

Cardiopulmonary baroreceptor control of muscle sympathetic nerve activity in heat-stressed humans

Whole body heating decreases central venous pressure (CVP) while increasing muscle sympathetic nerve activity (MSNA). In normothermia, similar decreases in CVP elevate MSNA, presumably via cardiopulmonary baroreceptor unloading. The purpose of this project was to identify whether increases in MSNA during whole body heating could be attributed to cardiopulmonary baroreceptor unloading coincident with the thermal challenge. Seven subjects were exposed to whole body heating while sublingual temperature, skin blood flow, heart rate, arterial blood pressure, and MSNA were monitored. During the heat stress, 15 ml/kg warmed saline was infused intravenously over 7-10 min to increase CVP and load the cardiopulmonary baroreceptors. We reported previously that this amount of saline was sufficient to return CVP to pre-heat stress levels. Whole body heating increased MSNA from 25 +/- 3 to 39 +/- 3 bursts/min (P < 0. 05). Central blood volume expansion via rapid saline infusion did not significantly decrease MSNA (44 +/- 4 bursts/min, P > 0.05 relative to heat stress period) and did not alter mean arterial blood pressure (MAP) or pulse pressure. To identify whether arterial baroreceptor loading decreases MSNA during heat stress, in a separate protocol MAP was elevated via steady-state infusion of phenylephrine during whole body heating. Increasing MAP from 82 +/- 3 to 93 +/- 4 mmHg (P < 0.05) caused MSNA to decrease from 36 +/- 3 to 15 +/- 4 bursts/min (P < 0.05). These data suggest that cardiopulmonary baroreceptor unloading during passive heating is not the primary mechanism resulting in elevations in MSNA. Moreover, arterial baroreceptors remain capable of modulating MSNA during heat stress.

NASA Discipline Cardiopulmonary↗

ICESat-2 Pointing Calibration and Geolocation Performance

ICESat-2 science requirements are dependent on the accurate real-time pointing control (i.e. geolocation control) and post-processed geolocation knowledge of the laser altimeter surface returns. Pre-launch pointing alignment errors and post-launch pointing alignment variation result in large geolocation errors that must be calibrated on orbit. In addition, the changing sun-orbit geometry causes thermal-mechanical forced laser frame alignment variations at the orbit period and trends from days, weeks and months. Early mission analysis computed precise post-launch laser beam alignment calibration. The alignment calibration was uploaded to the spacecraft and enabled the pointing control performance to achieve 4.4 ± 6.0 m, a significant improvement over the 45 m (1 σ) mission requirement. Laser frame alignment calibrations are used to reduce the alignment bias and time variation, as well as the orbital variation contributions to geolocation knowledge error from 6 m to 1.7 m (1 σ). Relative beam alignment of the six beams is calibrated and shown to contribute between 0.5 ± 0.1 m and 2.4 ± 0.2 m of remaining geolocation knowledge error. Independent geolocation assessment based on comparison to high-resolution digital elevation models agrees well with the calibration geolocation error estimates. The analysis demonstrates the ICESat-2 mission is performing far better than its geolocation knowledge requirement of 6.5 m (1 σ) after the laser frame alignment bias variation and orbital variation calibrations have been applied. Remaining geolocation error is beam dependent and ranges from 2.5 m for beam 6 to 4.4 m for beam 2 (mean + 1 σ).

S. B. Luthcke↗

MARCUS Ice Nucleating Particle Measurements (revised 7/2020)

These data list ice nucleating particle (INP) number concentrations active in the immersion freezing mode. Aerosol filters were collected during 4 voyages of the Aurora Australis vessel from 02 November 2017 to 22 March 2018, as part of the Measurements of Aerosols, Radiation and Clouds over the Southern Ocean (MARCUS) study. These voyages transected the Southern Ocean from Hobart, Tasmania to four Australian Antarctic Division stations, including three in Antarctica. Collections were made over alternating periods of 24 and 48 hours using open-faced polycarbonate filters that were approximately 18 m MSL, sited near the AOS trailer and other AMF measurements. The volume of air filtered ranged from 19000 to 38000 standard liters per filter sample. Filters were stored and returned frozen to Colorado State University (CSU), where immersion freezing measurements over a range from 0 to -28 degC were made using the CSU Ice Spectrometer (IS). Collected particles from each filter were resuspended in filtered, deionized water, and then dispensed into the IS and cooled to obtain cumulative INP temperature spectra. Aliquots of suspensions from selected samples were also heat treated (95 degC for 20 min) to denature and deactivate biological INPs, and digested in 10% H2O2 at 95 degC under UV-B for 20 min to remove all organic carbon INPs, prior to measurement using the IS.

54 ENVIRONMENTAL SCIENCES↗

Environmental Exposure Effects on Composite Materials for Commercial Aircraft

This period's activities were highlighted by continued long term and accelerated lab exposure testing, and by completion of all fabrication tasks on the optional material systems, AS1/3501-6 and Kevlar 49/F161-188. Initial baseline testing was performed on the two optional material systems. Long term exposure specimens were returned from three of the four ground rack sites and from two of the three aircraft locations. Test data from specimens returned from Dryden after 2 years exposure do not indicate continuing trends of strength reduction from the 1 year data. Test data from specimens returned from the Wellington, new Zealand ground rack and on Air New Zealand aircraft after 1 year exposure show strength changes fairly typical of other locations.

Hoffman, D. J.↗

Evidence of an Intrinsic Intraseasonal Oscillation over Tropical South America During Austral Summer

The intraseasonal variation (ISV) in the 30-60 day band, also known as Madden-Julian oscillation (MJO), has been studied for decades. Madden and Julian showed that the oscillation originated from the western Indian Ocean, propagated eastward, got enhanced over the maritime continent and weakened after passing over the dateline. Composite studies showed evidences of a signal in upper and lower level zonal wind propagating around the globe during an oscillation. Theoretical studies pointed out that the interaction with the warm ocean surface and the coupling with the convective and radiative processes in the atmosphere could manifest the oscillation, which propagates eastward via mutual feedbacks between the wave motions and the cumulus heating. Over tropical South America, no independent 30-60 day oscillation has been reported so far, despite that Amazon is the most distinct tropical convection center over the western hemisphere and the fluxes from its surface of tropical rainforests are close to that from the warm tropical ocean. Liebmann et al. showed a distinct spectral peak of 40-50 day oscillation in outgoing longwave radiation (OLR) over tropical South America and considered that was manifested by the MJO propagation. Nogues-Paegle et al. (2000) focused on a dipole pattern of the OLR anomaly with centers of action over the South Atlantic Convergence Zone (SACZ) and the subtropical plain. They used the regional 10-90 day filtered data and demonstrated this pattern could be represented by the fifth mode of the rotated empirical orthogonal function. Its principal component was further analyzed using the singular spectrum analysis. Their result showed two oscillatory modes with periods of 36-40 days and 22-28 days, of which the former was related to the MJO influence and the latter linked to the remote forcing over southwest of Australia, which produced a wave train propagating southeastward, rounding the southern tip of South America and returning back toward the northeast. The 22-28 day mode has distinct impact on SACZ, responsible for the regional seesaw pattern of alternating dry and wet conditions. In this study we will focus on the 30-60-day spectral band and investigate whether the independent oscillation source over tropical South America is existed. First, we will show the seasonal dependence of the tropical South American ISV in Section 3. Then, the leading principal modes of 30-60 day bandpass filtered 850-hPa velocity potential (VP850) will be computed to distinguish the stationary ISV over tropical South America (SISA) from the propagating MJO in the austral summertime in Section 4. The importance of SISA in representing the regional ISV over South America will be discussed. In Section 5, we will demonstrate the mass oscillation regime of SISA, which is well separated from that of MJO by the Andes, and the convective coupling with rainfall. The dynamical response of SISA and the impact on the South American summer monsoon (SASM) will be presented. Finally, we will give the concluding remarks.

Zhou, Jiayu↗

Past, present, and future life on Mars

Although the Viking results indicated that the surface of Mars is dry and lifeless, there is direct geomorphological evidence that Mars had large amounts of liquid water on its surface in the past. From a biological perspective the existence of liquid water, by itself, motivates the question of the origin of life on Mars. One of the martian meteorites dates back to this early period and may contain evidence consistent with life. The Mars environment 3.5 to 4.0 Gyr ago was comparable to that on the Earth at this time in that both contained liquid water. Life had originated on Earth and reached a fair degree of biological sophistication by 3.5 Gyr ago. To determine if life similarly arose on Mars may require extensive robotic exploration and ultimately human exploration. Intensive exploration of Mars will require a continued presence on the Martian surface and the development of a self sustaining community in which humans can live and work for very long periods of time. A permanent Mars research station can obtain its life support requirements directly from the martian environment enabling a high degree of self-sufficiency. In the longer term, it is possible that in the future we might restore a habitable climate on Mars, returning it to the life-bearing state it may have enjoyed early in its history.

NASA Center ARC↗

Comparison of Interstitial Fluid pH, PCO2, PO2 with Venous Blood Values During Repetitive Handgrip Exercise

We evaluated the use of a small, fiber optic sensor to measure pH, PCO2 and PO2 from forearm muscle interstitial fluid (IF) during handgrip dynamometry. PURPOSE: Compare pH, PCO2 and PO2 values obtained from venous blood with those from the IF of the flexor digitorum superficialis (FDS) during three levels of exercise intensity. METHODS: Six subjects (5M/1F), average age 29+/-5 yrs, participated in the study. A venous catheter was placed in the retrograde direction in the antecubital space and a fiber optic sensor (Paratrend, Diametrics Medical, Inc.) was placed through a 22 G catheter into the FDS muscle under ultrasound guidance. After a 45 min rest period, subjects performed three 5-min bouts of repetitive handgrip exercise (2s contraction/1 s relaxation) at attempted levels of 15%, 30% and 45% of maximal voluntary contraction. The order of the exercise bouts was random with the second and third bouts started after blood lactate had returned to baseline. Venous blood was sampled every minute during exercise and analyzed with an I-Stat CG-4+ cartridge, while IF fiber optic sensor measurements were obtained every 2 s. Change from pre-exercise baseline to end of exercise was computed for pH, PCO2 and PO2. Blood and IF values were compared with a paired t-test. RESULTS: Baseline values for pH, PCO2 and PO2 were 7.37+/-0.02, 46+/-4 mm Hg, and 36+/-6 mm Hg respectively in blood and 7.39+/-0.02, 44+/-6 mm Hg, and 35+/-14 mm Hg in IF. Average changes over all exercise levels are noted in the Table below. For each parameter the exercise-induced change was at least twice as great in IF as in blood. In blood and IF, pH and PCO2 increases were directly related to exercise intensity. Change in venous PO2 was unrelated to exercise intensity, while IF PO2 decreased with increases in exercise intensity. CONCLUSIONS: Measurement of IF pH, PCO2 and PO2 is more sensitive to exercise intensity than measurement of the same parameters in venous blood and provides continuous assessment during and after exercise.

Hagan, Ronald Donald↗