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At least 811 records · Page 45

A universal dose–response curve for radiochromic films

Purpose: This paper presents a model for dose–response curves of radiochromic films. It is based on a modified version of single-hit model to take into account the growth experienced by lithium salt of pentacosa-10,12-diynoic acid polymers after irradiation. Methods: Polymer growth in radiochromic films is a critical phenomenon that can be properly described by means of percolation theory to provide an appropriate distribution function for polymer sizes. Resulting functional form is a power function featuring a critical exponent and two adjustable parameters. Moreover, these parameters act as scaling factors setting a natural scale for sensitometric curves where the dependence on channel sensitivity is removed. A unique reduced response curve is then obtained from all the color channels describing film behavior independently of film dosimetry system. Results: Resulting functional form has been successfully tested in several sensitometric curves from different Gafchromic EBT models, providing excellent agreement with experimental data in a wide dose range up to about 40 Gy and low dose uncertainty. Conclusions: The model presented in this paper describes accurately the sensitometric curves of radiochromic films in wide dose ranges covering all typical ranges used in external radiotherapy. Resulting dose uncertainty is low enough to render a reasonably good performance in clinical applications. Due to cross-correlation, only one of the adjustable parameters is totally independent and characterizes film batches.

07 ISOTOPE AND RADIATION SOURCES↗

SU-G-TeP3-14: Three-Dimensional Cluster Model in Inhomogeneous Dose Distribution

Purpose: We aim to investigate 3D cluster formation in inhomogeneous dose distribution to search for new models predicting radiation tissue damage and further leading to new optimization paradigm for radiotherapy planning. Methods: The aggregation of higher dose in the organ at risk (OAR) than a preset threshold was chosen as the cluster whose connectivity dictates the cluster structure. Upon the selection of the dose threshold, the fractional density defined as the fraction of voxels in the organ eligible to be part of the cluster was determined according to the dose volume histogram (DVH). A Monte Carlo method was implemented to establish a case pertinent to the corresponding DVH. Ones and zeros were randomly assigned to each OAR voxel with the sampling probability equal to the fractional density. Ten thousand samples were randomly generated to ensure a sufficient number of cluster sets. A recursive cluster searching algorithm was developed to analyze the cluster with various connectivity choices like 1-, 2-, and 3-connectivity. The mean size of the largest cluster (MSLC) from the Monte Carlo samples was taken to be a function of the fractional density. Various OARs from clinical plans were included in the study. Results: Intensive Monte Carlo study demonstrates the inverse relationship between the MSLC and the cluster connectivity as anticipated and the cluster size does not change with fractional density linearly regardless of the connectivity types. An initially-slow-increase to exponential growth transition of the MSLC from low to high density was observed. The cluster sizes were found to vary within a large range and are relatively independent of the OARs. Conclusion: The Monte Carlo study revealed that the cluster size could serve as a suitable index of the tissue damage (percolation cluster) and the clinical outcome of the same DVH might be potentially different.

07 ISOTOPE AND RADIATION SOURCES↗

Shear-Induced Anisotropy of Concentrated Multi-walled Carbon Nanotube Suspensions Using X-ray Scattering

X-ray scattering is used to measure particle orientation in concentrated multiwalled carbon nanotube (MWNT) suspensions under shear flow. MWNTs were dispersed in a Newtonian suspending fluid (uncured epoxy). The dispersions exhibit shear thinning, approaching the matrix viscosity at high shear rates. This is accompanied by progressive development of MWNT orientation along the flow direction with increasing shear rate. The impact of MWNT aspect ratio and concentration on steady-state orientation is explored. In one sample (2 wt. % dispersion of short MWNTs), orientation was measured in both the flow-gradient (1-2) and flow-vorticity (1-3) planes of shear flow to provide a more complete picture of the three-dimensional orientation state. Also in this sample, 1-3 plane measurements were conducted using both small- and wide-angle x-ray scattering (SAXS and WAXS). While the two methods produce qualitatively similar results, WAXS-derived measures of flow-induced anisotropy are consistently larger than SAXS data. In transient measurements following step-down in shear rate, MWNT orientation is found to decrease on similar time scales as viscosity increases. Prolonged growth of storage modulus is observed following flow cessation, accompanied by an unexpectedly rapid partial loss of MWNT orientation. The rheological and orientation data are discussed in terms of distortion, breakdown, and reformation of percolated MWNT networks in these samples.

77 NANOSCIENCE AND NANOTECHNOLOGY↗

Modeling of the blood rheology in steady-state shear flows

We undertake here a systematic study of the rheology of blood in steady-state shear flows. As blood is a complex fluid, the first question that we try to answer is whether, even in steady-state shear flows, we can model it as a rheologically simple fluid, i.e., we can describe its behavior through a constitutive model that involves only local kinematic quantities. Having answered that question positively, we then probe as to which non-Newtonian model best fits available shear stress vs shear-rate literature data. We show that under physiological conditions blood is typically viscoplastic, i.e., it exhibits a yield stress that acts as a minimum threshold for flow. We further show that the Casson model emerges naturally as the best approximation, at least for low and moderate shear-rates. We then develop systematically a parametric dependence of the rheological parameters entering the Casson model on key physiological quantities, such as the red blood cell volume fraction (hematocrit). For the yield stress, we base our description on its critical, percolation-originated nature. Thus, we first determine onset conditions, i.e., the critical threshold value that the hematocrit has to have in order for yield stress to appear. It is shown that this is a function of the concentration of a key red blood cell binding protein, fibrinogen. Then, we establish a parametric dependence as a function of the fibrinogen and the square of the difference of the hematocrit from its critical onset value. Similarly, we provide an expression for the Casson viscosity, in terms of the hematocrit and the temperature. A successful validation of the proposed formula is performed against additional experimental literature data. The proposed expression is anticipated to be useful not only for steady-state blood flow modeling but also as providing the starting point for transient shear, or more general flow modeling.

42 ENGINEERING↗

Rheological signatures of gelation and effect of shear melting on aging colloidal suspension

Colloidal suspensions that are out of thermodynamic equilibrium undergo physical aging wherein their structure evolves to lower the free energy. In aqueous suspension of Laponite, physical aging accompanies increases of elastic and viscous moduli as a function of time. In this work, we study temporal evolution of elastic and viscous moduli at different frequencies and observe that freshly prepared aqueous suspension of Laponite demonstrates identical rheological behavior reported for the crosslinking polymeric materials undergoing chemical gelation. Consequently at a certain time, tan δ is observed to be independent of frequency. However, for samples preserved under rest condition for longer duration before applying the shear melting, the liquid to solid transition subsequent to shear melting shows greater deviation from classical gelation. We also obtain continuous relaxation time spectra from the frequency dependence of viscous modulus. We observe that, with an increase in the rest time, continuous relaxation time spectrum shows gradual variation from negative slope, describing dominance of fast relaxation modes to positive slope representing dominance of slow relaxation modes. We propose that the deviation from gelation behavior for the shear melted suspensions originates from inability of shear melting to completely break the percolated structure thereby creating unbroken aggregates. The volume fraction of such unbroken aggregates increases with the rest time. For small rest times presence of fewer number of unbroken aggregates cause deviation from the classical gelation. On the other hand, at high rest times presence of greater fraction of unbroken aggregates subsequent to shear melting demonstrate dynamic arrest leading to inversion of relaxation time spectra.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

Self-organization of helium precipitates into elongated channels within metal nanolayers

Material degradation due to precipitation of implanted helium (He) is a key concern in nuclear energy. Decades of research have mapped out the fate of He precipitates in metals, from nucleation and growth of equiaxed bubbles and voids to formation and bursting of surface blisters. By contrast, we show that He precipitates confined within nanoscale metal layers depart from their classical growth trajectories: They self-organize into elongated channels. These channels form via templated nucleation of He precipitates along layer surfaces followed by their growth and spontaneous coalescence into stable precipitate lines. The total line length and connectivity increases with the amount of implanted He, indicating that these channels ultimately interconnect into percolating “vascular” networks. In conclusion, vascularized metal composites promise a transformative solution to He-induced damage by enabling in operando outgassing of He and other impurities while maintaining material integrity.

36 MATERIALS SCIENCE↗

Unusual behavior of cuprates explained by heterogeneous charge localization

The discovery of high-temperature superconductivity in cuprates ranks among the major scientific milestones of the past half century, yet pivotal questions regarding the complex phase diagram of these materials remain unanswered. Generally thought of as doped charge-transfer insulators, these complex oxides exhibit pseudogap, strange-metal, superconducting, and Fermi liquid behavior with increasing hole-dopant concentration. Motivated by recent experimental observations, here we introduce a phenomenological model wherein exactly one hole per planar copper-oxygen unit is delocalized with increasing doping and temperature. The model is percolative in nature, with parameters that are highly consistent with experiments. It comprehensively captures key unconventional experimental results, including the temperature and the doping dependence of the pseudogap phenomenon, the strange-metal linear temperature dependence of the planar resistivity, and the doping dependence of the superfluid density. The success and simplicity of the model greatly demystify the cuprate phase diagram and point to a local superconducting pairing mechanism.

75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND↗

Kinetic frustration by limited bond availability controls the LAT protein condensation phase transition on membranes

LAT is a membrane-linked scaffold protein that undergoes a phase transition to form a two-dimensional protein condensate on the membrane during T cell activation. Governed by tyrosine phosphorylation, LAT recruits various proteins that ultimately enable condensation through a percolation network of discrete and selective protein-protein interactions. Here, we describe detailed kinetic measurements of the phase transition, along with coarse-grained model simulations, that reveal that LAT condensation is kinetically frustrated by the availability of bonds to form the network. Unlike typical miscibility transitions in which compact domains may coexist at equilibrium, the LAT condensates are dynamically arrested in extended states, kinetically trapped out of equilibrium. Modeling identifies the structural basis for this kinetic arrest as the formation of spindle arrangements, favored by limited multivalent binding interactions along the flexible, intrinsically disordered LAT protein. These results reveal how local factors controlling the kinetics of LAT condensation enable formation of different, stable condensates, which may ultimately coexist within the cell.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Hierarchical crack buffering triples ductility in eutectic herringbone high-entropy alloys

In human-made malleable materials, microdamage such as cracking usually limits material lifetime. Some biological composites, such as bone, have hierarchical microstructures that tolerate cracks but cannot withstand high elongation. Here, we demonstrate a directionally solidified eutectic high-entropy alloy (EHEA) that successfully reconciles crack tolerance and high elongation. The solidified alloy has a hierarchically organized herringbone structure that enables bionic-inspired hierarchical crack buffering. This effect guides stable, persistent crystallographic nucleation and growth of multiple microcracks in abundant poor-deformability microstructures. Hierarchical buffering by adjacent dynamic strain–hardened features helps the cracks to avoid catastrophic growth and percolation. Our self-buffering herringbone material yields an ultrahigh uniform tensile elongation (~50%), three times that of conventional nonbuffering EHEAs, without sacrificing strength.

36 MATERIALS SCIENCE↗

Imaging quantum melting in a disordered 2D Wigner solid

Two-dimensional strongly interacting electrons crystalize into a solid phase known as the Wigner crystal at low densities and form a Fermi liquid at high densities. At intermediate densities, the two-dimensional solid evolves into a strongly correlated liquid phase around a critical density. We observed this quantum melting of a disordered Wigner solid in bilayer molybdenum diselenide (MoSe2) using a noninvasive scanning tunneling microscopy imaging technique. At low densities, the Wigner solid forms nanocrystalline domains pinned by local disorder. It exhibits a quantum densification behavior with increased densities in the solid phase. Above a threshold density, the Wigner solid melts locally and enters a mixed phase in which solid and liquid regions coexist. The liquid regions expand and form a percolation network at even higher densities.

Xiang, Ziyu↗

Community Structure and Microbial Associations in Sediment-Free Methanotrophic Enrichment Cultures from a Marine Methane Seep

We report Syntrophic consortia of anaerobic methanotrophic archaea (ANME) and sulfate-reducing bacteria (SRB) consume large amounts of methane and serve as the foundational microorganisms in marine methane seeps. Despite their importance in the carbon cycle, research on the physiology of ANME-SRB consortia has been hampered by the slow growth and complex physicochemical environment the consortia inhabit. Here, we report successful sediment-free enrichment of ANME-SRB consortia from deep-sea methane seep sediments in the Santa Monica Basin, California. Anoxic Percoll density gradients and size-selective filtration were used to separate ANME-SRB consortia from sediment particles and single cells to accelerate the cultivation process. Over a 3-year period, a subset of the sediment-associated ANME and SRB lineages, predominantly comprised of ANME-2a/2b (“Candidatus Methanocomedenaceae”) and their syntrophic bacterial partners, SEEP-SRB1/2, adapted and grew under defined laboratory conditions. Metagenome-assembled genomes from several enrichments revealed that ANME-2a, SEEP-SRB1, and Methanococcoides in different enrichments from the same inoculum represented distinct species, whereas other coenriched microorganisms were closely related at the species level. This suggests that ANME, SRB, and Methanococcoides are more genetically diverse than other members in methane seeps. Flow cytometry sorting and sequencing of cell aggregates revealed that Methanococcoides, Anaerolineales, and SEEP-SRB1 were overrepresented in multiple ANME-2a cell aggregates relative to the bulk metagenomes, suggesting they were physically associated and possibly interacting. Overall, this study represents a successful case of selective cultivation of anaerobic slow-growing microorganisms from sediments based on their physical characteristics, introducing new opportunities for detailed genomic, physiological, biochemical, and ecological analyses. Biological anaerobic oxidation of methane (AOM) coupled with sulfate reduction represents a large methane sink in global ocean sediments. Methane consumption is carried out by syntrophic archaeal-bacterial consortia and fuels a unique ecosystem, yet the interactions in these slow-growing syntrophic consortia and with other associated community members remain poorly understood. The significance of this study is the establishment of sediment-free enrichment cultures of anaerobic methanotrophic archaea and sulfate-reducing bacteria performing AOM with sulfate using selective cultivation approaches based on size, density, and metabolism. By reconstructing microbial genomes and analyzing community composition of the enrichment cultures and cell aggregates, we shed light on the diversity of microorganisms physically associated with AOM consortia beyond the core syntrophic partners. These enrichment cultures offer simplified model systems to extend our understanding of the diversity of microbial interactions within marine methane seeps.

59 BASIC BIOLOGICAL SCIENCES↗

Peculiarities of Photoprocesses in Poly(9,9-di-n-octylfluorenyl-2,7-diyl) Films Doped with Potassium Iodide

The spectral-luminescence properties of poly(9,9-di-n-octylfluorenyl-2,7-diyl) (PFO) films doped with potassium iodide are investigated. It is found that the addition of potassium iodide at concentrations of 0.1–1% leads to a drop in the degree of ordering of the PFO films and decreases the fluorescence intensity and lifetime of the polymer. The kinetics of photoluminescence of PFO–KI films is studied in nano-, micro-, and millisecond time bands. Analysis of the experimental data on long-term luminescence using the percolation model showed that the addition of potassium iodide to the polymer increases the degree of disordering of the film. Investigations of the effect of an external magnetic field on the PFO luminescence over a wide time range indicate a complex character of the time dependence of the magnetic effect. The changes in both the magnitude and sign of the magnetic effect g(B) are observed over the entire measured time range.

75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND↗

Dynamic magnetic permeability of the heterogeneous nanosystems based on (Co{sub 41}Fe{sub 39}B{sub 20}){sub x}(SiO{sub 2}){sub 100–} {sub x} composites

Thin films of (Co{sub 41}Fe{sub 39}B{sub 20}){sub x}(SiO{sub 2}){sub 100–} {sub x} nanocomposites and hybrid nanocomposite–semiconductor [(Co{sub 41}Fe{sub 39}B{sub 20}){sub x}(SiO{sub 2}){sub 100–} {sub x}/C]{sub 50} multilayers are synthesized by ion-beam deposition at various contents x of ferromagnetic metallic Co{sub 41}Fe{sub 39}B{sub 2O} nanogranules in an SiO{sub 2} matrix and at various carbon layer thicknesses h < 2 nm. Their magnetic and electrical properties, high-frequency magnetic permeability, magnetooptical spectra, and FMR spectra are studied. It is found that both the single-layer nanocomposites and the multilayers with carbon interlayers are superparamagnetic at x < x{sub per}, where x{sub per} is the electric conduction percolation threshold: a hysteresis at room temperature is absent, and the blocking temperature determined in quasi-static measurements does not exceed 20–30 K and weakly depends on the carbon layer thickness. At a carbon layer thickness h = 1.2–1.8 nm, the real and imaginary parts of complex magnetic permeability at 50 MHz and room temperature are substantially higher than those of the nanocomposites without carbon layers: their values are typical of ferromagnets. This dependence points to an exchange interaction between nanogranules in layers through a carbon interlayer. The influence of a conducting layer on the static and dynamic magnetic properties of a system of interacting superparamagnetic particles is discussed.

36 MATERIALS SCIENCE↗

Universal Frequency Dependence of the Hopping AC Conductance in p-Ge/GeSi Structures in the Integer Quantum Hall Effect Regime

The hopping ac conductance, which is realized at the transverse conductance minima in the regime of the integer Hall effect, has been measured using a combination of acoustic and microwave methods. Measurements have been made in the p-GeSi/Ge/GeSi structures with quantum wells in a wide frequency range (30–1200 MHz). The experimental frequency dependences of the real part of ac conductance σ{sub 1} have been interpreted on the basis of the model presuming hops between localized electronic states belonging to isolated clusters. At high frequencies, dominating clusters are pairs of close states; upon a decrease in frequency, large clusters that merge into an infinite percolation cluster as the frequency tends to zero become important. In this case, the frequency dependences of the ac conductance can be represented by a universal curve. The scaling parameters and their magnetic-field dependence have been determined.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

Transport, Magnetic, and Memristive Properties of a Nanogranular (CoFeB){sub x}(LiNbO{sub y}){sub 100–x} Composite Material

The properties of (CoFeB){sub x}(LiNbO{sub y}){sub 100–x} nanocomposite films with a ferromagnetic alloy content x = 6–48 at % are comprehensively studied. The films are shown to consist of ensembles of CoFe granules 2–4 nm in size, which are strongly elongated (up to 10–15 nm) in the nanocomposite growth direction and are located in an LiNbO{sub y} matrix with a high content of Fe{sup 2+} and Co{sup 2+} magnetic ions (up to 3 × 1022 cm{sup –3}). At T ≤ 25 K, a paramagnetic component of the magnetization of nanocomposites is detected along with a ferromagnetic component, and the contribution of the former component is threefold that of the latter. A hysteresis of the magnetization is observed below the percolation threshold up to x ≈ 33 at %, which indicates the appearance of a superferromagnetic order in the nanocomposites. The temperature dependence of the electrical conductivity of the nanocomposites in the range T ≈ 10–200 K on the metallic side of the metal–insulator transition (44 at % < x < 48 at %) is described by a logarithmic law σ(T) ∝ lnT. This law changes into the law of “1/2” at x ≤ 40 at %. The tunneling anomalous Hall effect is strongly suppressed and the longitudinal conductivity turns out to be lower than in a (CoFeB){sub x}(AlO{sub y}){sub 100–x} composite material by an order of magnitude. The capacitor structures based on (CoFeB){sub x}(LiNbO{sub y}){sub 100–x} films exhibit resistive switching effects. They are related to (i) the formation of isolated chains of elongated granules and an anomalously strong decrease in the resistance in fields E > 10{sup 4} V/cm because of the suppression of Coulomb blockage effects and the generation of oxygen vacancies V{sub O} and (ii) the injection (or extraction) of V{sub O} vacancies (depending on the sign of voltage) into a strongly oxidized layer in the nanocomposites, which is located near an electrode of the structure and controls its resistance. The number of stable resistive switchings exceeds 10{sup 5} at a resistance ratio R{sub off}/R{sub on} ~ 50.

36 MATERIALS SCIENCE↗

Unusual Behavior of the Coercive Field in a (CoFeB){sub x}(LiNbO{sub y}){sub 100 –x} Nanocomposite with a High Content of Magnetic Ions in an Insulating Matrix

The temperature behavior of the coercive field H{sub c}(T) and the magnetic anisotropy in (CoFeB){sub x}(LiNbO{sub y}){sub 100 –x} nanocomposite films with a ferromagnetic alloy content x = 33–48 at % near the metal–insulator transition (x{sub c} ≈ 42 at %) have been studied by the magnetometry and ferromagnetic resonance methods. The films were ensembles of CoFe granules with lateral sizes of 2–4 nm, which are highly elongated (up to 10–15 nm) in the nanocomposite growth direction and embedded in a LiNbO{sub y} matrix with a high content of magnetic Fe{sup 2+} and Co{sup 2+} ions (up to 3 × 10{sup 22} cm{sup –3}). A nonmonotonic behavior of H{sub c}(T), viz., a sharp minimum at a temperature T{sub F} ≈ 50 K close to the blocking temperature (T{sub b}{sup ∗} ≈ 70 K) of the granule magnetic moment, has been detected in samples with x < 42 at %. The effective field of the perpendicular growth anisotropy (0.4–0.8 kOe) turns out to be an order of magnitude lower than the field of the granule shape anisotropy (about 7 kOe) and increases with x. The revealed peculiarities are explained by the fact that, apart from the ferromagnetic intergranular exchange interaction in an infinite cluster, the surface anisotropy effects involving magnetic ions in a thin layer adjacent to the cluster and responsible for the surface interaction fluctuations play a big role in the investigated percolation nanocomposites, enhancing the nanocomposite demagnetization at T ≈ T{sub F} ~ T{sub b}{sup ∗}.

36 MATERIALS SCIENCE↗

Phase transitions in strongly interacting matter

I discuss the phase structure of hadronic matter in terms of the basic dynamical and geometrical features of hadrons. Increasing the density of constituents of finite spatial extension, by increasing the temperature T or the baryochemical potential µ, eventually “fills the box” and eliminates the physical vacuum. The corresponding transition as function of T and µ can be determined through percolation theory. At low baryon density, this means a fusion of overlapping mesonic bags to one large bag, while at high baryon density, hard core repulsion restricts the spatial mobility of baryons. As a consequence, there are two distinct limiting regimes for hadronic matter.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Role of electrostatic fluctuations in doped semiconductors upon the transition from band to hopping conduction (by the example of p-Ge:Ga)

The electrostatic model of ionization equilibrium between hydrogen-like acceptors and v-band holes in crystalline covalent p-type semiconductors is developed. The range of applicability of the model is the entire insulator side of the insulator–metal (Mott) phase transition. The density of the spatial distribution of acceptor- and donor-impurity atoms and holes over a crystal was assumed to be Poissonian and the fluctuations of their electrostatic potential energy, to be Gaussian. The model takes into account the effect of a decrease in the energy of affinity of an ionized acceptor to a v-band hole due to Debye–Hückel ion screening by both free v-band holes and localized holes hopping over charge states (0) and (–1) of acceptors in the acceptor band. All donors are in charge state (+1) and are not directly involved in the screening, but ensure the total electroneutrality of a sample. In the quasiclassical approximation, analytical expressions for the root-mean-square fluctuation of the v-band hole energy W{sub p} and effective acceptor bandwidth W{sub a} are obtained. In calculating W{sub a}, only fluctuations caused by the Coulomb interaction between two nearest point charges (impurity ions and holes) are taken into account. It is shown that W{sub p} is lower than W{sub a}, since electrostatic fluctuations do not manifest themselves on scales smaller than the average de Broglie wavelength of a free hole. The delocalization threshold for v-band holes is determined as the sum of the diffusive-percolation threshold and exchange energy of holes. The concentration of free v-band holes is calculated at the temperature T{sub j} of the transition from dc band conductivity to conductivity implemented via hopping over acceptor states, which is determined from the virial theorem. The dependence of the differential energy of the thermal ionization of acceptors at the temperature 3T{sub j}/2 on their concentration N and degree of compensation K (the ratio between the donor and acceptor concentrations) is determined. Good quantitative agreement between the results of the calculation and data on the series of neutron transmutation doped p-Ge samples is obtained up to the Mott transition without using any fitting parameters.

36 MATERIALS SCIENCE↗