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At least 811 records · Page 45

PHAT stellar cluster survey. II. Andromeda Project cluster catalog

We construct a stellar cluster catalog for the Panchromatic Hubble Andromeda Treasury (PHAT) survey using image classifications collected from the Andromeda Project citizen science website. We identify 2753 clusters and 2270 background galaxies within ∼0.5 deg{sup 2} of PHAT imaging searched, or ∼400 kpc{sup 2} in deprojected area at the distance of the Andromeda Galaxy (M31). These identifications result from 1.82 million classifications of ∼20,000 individual images (totaling ∼7 gigapixels) by tens of thousands of volunteers. We show that our crowd-sourced approach, which collects >80 classifications per image, provides a robust, repeatable method of cluster identification. The high spatial resolution Hubble Space Telescope images resolve individual stars in each cluster and are instrumental in the factor of ∼6 increase in the number of clusters known within the survey footprint. We measure integrated photometry in six filter passbands, ranging from the near-UV to the near-IR. PHAT clusters span a range of ∼8 magnitudes in F475W (g-band) luminosity, equivalent to ∼4 decades in cluster mass. We perform catalog completeness analysis using >3000 synthetic cluster simulations to determine robust detection limits and demonstrate that the catalog is 50% complete down to ∼500 M{sub ⊙} for ages <100 Myr. We include catalogs of clusters, background galaxies, remaining unselected candidates, and synthetic cluster simulations, making all information publicly available to the community. The catalog published here serves as the definitive base data product for PHAT cluster science, providing a census of star clusters in an L{sup ⋆} spiral galaxy with unmatched sensitivity and quality.

79 ASTRONOMY AND ASTROPHYSICS↗

The very luminous supernova remnant in NGC 6946

In this paper, I discuss an extremely luminous X-ray source found on the northern arm of the nearly face-on spiral galaxy NGC 6946. The source was originally discovered in an Einstein observation, but the poor spatial resolution prevented an accurate identification. Here, Roentgen Satellite (ROSAT) data provide a position to approximately 5 sec - 10 sec. The spectrum is rather soft, and moderately absorbed. The source appears to be local to NGC 6946 and a supernova remnant, based upon the positional coincidence with an optical counterpart. The luminosity, assuming a distance to NGC 6946 of 5.1 Mpc, is 2.8 x 10(exp 39) erg/s, among the highest known X-ray luminosities of a remnant. The optical counterpart is at least 100 years old.

Schlegel, Eric M.↗

Planck intermediate results. XXVI. Optical identification and redshifts of Planck clusters with the RTT150 telescope

In this paper, we present the results of approximately three years of observations of Planck Sunyaev-Zeldovich (SZ) sources with the Russian-Turkish 1.5 m telescope (RTT150), as a part of the optical follow-up programme undertaken by the Planck collaboration. During this time period approximately 20% of all dark and grey clear time available at the telescope was devoted to observations of Planck objects. Some observations of distant clusters were also done at the 6 m Bolshoi Telescope Alt-azimutalnyi (BTA) of the Special Astrophysical Observatory of the Russian Academy of Sciences. In total, deep, direct images of more than one hundred fields were obtained in multiple filters. We identified 47 previously unknown galaxy clusters, 41 of which are included in the Planck catalogue of SZ sources. The redshifts of 65 Planck clusters were measured spectroscopically and 14 more were measured photometrically. We discuss the details of cluster optical identifications and redshift measurements. Finally, we also present new spectroscopic redshifts for 39 Planck clusters that were not included in the Planck SZ source catalogue and are published here for the first time.

79 ASTRONOMY AND ASTROPHYSICS↗

Extending a Tandem Mass Spectral Library to Include MS{sup 2} Spectra of Fragment Ions Produced In-Source and MS{sup n} Spectra

Tandem mass spectral library searching is finding increased use as an effective means of determining chemical identity in mass spectrometry-based omics studies. We previously reported on constructing a tandem mass spectral library that includes spectra for multiple precursor ions for each analyte. Here we report our method for expanding this library to include MS{sup 2} spectra of fragment ions generated during the ionization process (in-source fragment ions) as well as MS{sup 3} and MS{sup 4} spectra. These can assist the chemical identification process. A simple density-based clustering algorithm was used to cluster all significant precursor ions from MS{sup 1} scans for an analyte acquired during an infusion experiment. The MS{sup 2} spectra associated with these precursor ions were grouped into the same precursor clusters. Subsequently, a new top-down hierarchical divisive clustering algorithm was developed for clustering the spectra from fragmentation of ions in each precursor cluster, including the MS{sup 2} spectra of the original precursors and of the in-source fragments as well as the MS{sup n} spectra. This algorithm starts with all the spectra of one precursor in one cluster and then separates them into sub-clusters of similar spectra based on the fragment patterns. Herein, we describe the algorithms and spectral evaluation methods for extending the library. The new library features were demonstrated by searching the high resolution spectra of E. coli extracts against the extended library, allowing identification of compounds and their in-source fragment ions in a manner that was not possible before. .

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Software Requirement Document: Benchmarking Algorithms for RadioNuclide Identification (BARNI)

The Department of Energy (DOE) Office of Nuclear Smuggling Detection and Deterrence (NSDD) seeks to improve the performance of RadioIsotope Identification Devices (RIIDs). RIIDs enable users to identifying threat nuclides in applications such as secondary search, facility inspection, and emergency response. As part of this effort NSDD has developed Replicative Assessment of Spectroscopic Equipment (RASE), an open-source tool which generates synthetic spectra and analyzes them with vendor’s radionuclide identification software in order to evaluate performance.

61 RADIATION PROTECTION AND DOSIMETRY↗

A Quick Look at the 3 GHz Radio Sky. II. Hunting for DRAGNs in the VLA Sky Survey

Active galactic nuclei (AGNs) can often be identified in radio images as two lobes, sometimes connected to a core by a radio jet. This multicomponent morphology unfortunately creates difficulties for source finders, leading to components that are (a) separate parts of a wider whole, and (b) offset from the multiwavelength cross identification of the host galaxy. In this work we define an algorithm, DRAGN HUNTER , for identifying double radio sources associated with AGNs (DRAGNs) from component catalog data in the first epoch Quick Look images of the high-resolution (≈3" beam size) Very Large Array Sky Survey (VLASS). We use DRAGN HUNTER to construct a catalog of >17,000 DRAGNs in VLASS for which contamination from spurious sources is estimated at ≈11%. A “high-fidelity” sample consisting of 90% of our catalog is identified for which contamination is <3%. Host galaxies are found for ≈13,000 DRAGNs as well as for an additional 234,000 single-component radio sources. Using these data, we explore the properties of our DRAGNs, finding them to be typically consistent with Fanaroff–Riley class II sources and to allow us to report the discovery of 31 new giant radio galaxies identified using VLASS.

79 ASTRONOMY AND ASTROPHYSICS↗

Autonomous METLIN-Guided In-source Fragment Annotation for Untargeted Metabolomics

Computational metabolite annotation in untargeted profiling aims at uncovering neutral molecular masses of underlying metabolites and assign those with putative identities. Existing annotation strategies rely on the observation and annotation of adducts to determine metabolite neutral masses. However, a significant fraction of features usually detected in untargeted experiments remains unannotated, which limits our ability to determine neutral molecular masses. Despite the availability of tools to annotate, relatively few of them benefit from the inherent presence of in-source fragments in liquid chromatography-electrospray ionization-mass spectrometry. Here, we introduce a strategy to annotate in-source fragments in untargeted data using low-energy tandem mass spectrometry (MS) spectra from the METLIN library. Our algorithm, MISA (METLIN-guided in-source annotation), compares detected features against low-energy fragments from MS/MS spectra, enabling robust annotation and putative identification of metabolic features based on low-energy spectral matching. The algorithm was evaluated through an annotation analysis of a total of 140 metabolites across three different sets of biological samples analyzed with liquid chromatography-mass spectrometry. Results showed that, in cases where adducts were not formed or detected, MISA was able to uncover neutral molecular masses by in-source fragment matching. MISA was also able to provide putative metabolite identities via two annotation scores. These scores take into account the number of in-source fragments matched and the relative intensity similarity between the experimental data and the reference low-energy MS/MS spectra. Overall, results showed that in-source fragmentation is a highly frequent phenomena that should be considered for comprehensive feature annotation. Thus, combined with adduct annotation, this strategy adds a complementary annotation layer, enabling in-source fragments to be annotated and increasing putative identification confidence. The algorithm is integrated into the XCMS Online platform and is freely available at http://xcmsonline.scripps.edu.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Uncovering Special Nuclear Materials by Low-energy Nuclear Reaction Imaging

Weapons-grade uranium and plutonium could be used as nuclear explosives with extreme destructive potential. The problem of their detection, especially in standard cargo containers during transit, has been described as “searching for a needle in a haystack” because of the inherently low rate of spontaneous emission of characteristic penetrating radiation and the ease of its shielding. Currently, the only practical approach for uncovering well-shielded special nuclear materials is by use of active interrogation using an external radiation source. However, the similarity of these materials to shielding and the required radiation doses that may exceed regulatory limits prevent this method from being widely used in practice. We introduce a low-dose active detection technique, referred to as low-energy nuclear reaction imaging, which exploits the physics of interactions of multi-MeV monoenergetic photons and neutrons to simultaneously measure the material’s areal density and effective atomic number, while confirming the presence of fissionable materials by observing the beta-delayed neutron emission. For the first time, we demonstrate identification and imaging of uranium with this novel technique using a simple yet robust source, setting the stage for its wide adoption in security applications.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

SS Cygni as a hard X-ray source identified with the scanning modulation collimator on HEAO 1

Hard X-ray emission from a 15 min by 1.5 deg area containing SS Cygni had previously been reported and identified with SS Cygni. This paper reports a 0.4 sq arc min measurement of the position of the X-ray source with the HEAO 1 modulation collimator experiment which leads to an unequivocal identification of SS Cygni as an X-ray emitter in the 2-10 keV energy range. The historical light curve in hard X-rays was also investigated by analyzing relevant Uhuru data, and two instances of possible source detection in the 2-6 keV band were noted. From Ariel 5 observations it is calculated that the X-ray luminosity of SS Cygni in the 2-10 keV energy range is of the order of 10 to the 33rd erg/sec in the optical low state and probably at least an order of magnitude less in the high state. By contrast, the soft X-ray luminosity increases by an order of magnitude between the optical low and high states. A coronal model or accretion onto the white dwarf can account for the inverse correlation of the soft and hard X-rays.

Fabbiano, G.↗

HEAO 1 observations of 4U1232+07

An analysis of the NRL HEAO 1 observations of the Virgo cluster and 3C 273 has revealed X-ray emission from a region between these two objects. The most satisfactory explanation is the presence of two weak X-ray sources, for which error boxes have been obtained. One source is likely to be the peculiar galaxy IC 3576, suggested by Margon et al. (1972) as the source 2U 1231+07=4U 1232+07. The error box resulting from combining the present observations with the 4U data strengthen the X-ray identification with this extremely interesting galaxy. There are numerous possibilities for the other X-ray source, including the interacting pair of galaxies NGC 4410a and NGC 4410b (NGC 4410a/b).

Bhavsar, S. P.↗

AUTOMATED TRANSIENT IDENTIFICATION IN THE DARK ENERGY SURVEY

We describe an algorithm for identifying point-source transients and moving objects on reference-subtracted optical images containing artifacts of processing and instrumentation. The algorithm makes use of the supervised machine learning technique known as Random Forest. We present results from its use in the Dark Energy Survey Supernova program (DES-SN), where it was trained using a sample of 898,963 signal and background events generated by the transient detection pipeline. After reprocessing the data collected during the first DES-SN observing season (2013 September through 2014 February) using the algorithm, the number of transient candidates eligible for human scanning decreased by a factor of 13.4, while only 1.0% of the artificial Type Ia supernovae (SNe) injected into search images to monitor survey efficiency were lost, most of which were very faint events. Here we characterize the algorithm’s performance in detail, and we discuss how it can inform pipeline design decisions for future time-domain imaging surveys, such as the Large Synoptic Survey Telescope and the Zwicky Transient Facility. An implementation of the algorithm and the training data used in this paper are available at at http://portal.nersc.gov/project/dessn/autoscan.

79 ASTRONOMY AND ASTROPHYSICS↗

Optical identification of A0620-00

The optical object corresponding to the transient X-ray source A0620-00 is identified. The position (1950) of this object is given to a precision of 2 sec as: right ascension 6 hr 20 min 11.2 sec, declination -0 deg 19 min 10 sec. It is noted that the object has undergone a substantial change in brightness since the X-ray source was first detected and that three low-dispersion spectra of it show no emission or absorption features. Similarities between the present object and Sco X-1 are discussed.

Boley, F.↗

System identification test using active members

A modal test using active members as the excitation source has been performed on the Precision Truss. Using the step sine testing technique, the frequency response functions are obtained and the modal parameters are extracted by the curve-fitting method. Total of 10 global modes and 3 local modes are obtained. The results are compared with those obtained by the conventional external excitation test.

Chen, Jay-Chung↗

Informed-Proteomics: open-source software package for top-down proteomics

Top-down proteomics involves the analysis of intact proteins. This approach is very attractive as it allows for analyzing proteins in their endogenous form without proteolysis, preserving valuable information about post-translation modifications, isoforms, proteolytic processing or their combinations collectively called proteoforms. Moreover, the quality of the top-down LC-MS/MS datasets is rapidly increasing due to advances in the liquid chromatography and mass spectrometry instrumentation and sample processing protocols. However, the top-down mass spectra are substantially more complex compare to the more conventional bottom-up data. To take full advantage of the increasing quality of the top-down LC-MS/MS datasets there is an urgent need to develop algorithms and software tools for confident proteoform identification and quantification. In this study we present a new open source software suite for top-down proteomics analysis consisting of an LC-MS feature finding algorithm, a database search algorithm, and an interactive results viewer. The presented tool along with several other popular tools were evaluated using human-in-mouse xenograft luminal and basal breast tumor samples that are known to have significant differences in protein abundance based on bottom-up analysis.

Environmental Molecular Sciences Laboratory↗

Possible detection of an extreme-ultraviolet source at 500 A

Evidence for an extreme-ultraviolet source in the constellation Pavo is presented. The potential source, which was observed in the 500-780-A band, has an intensity of 35 + or - 9 mJy. Positional overlap suggests possible identification with the ultraviolet-intense star HD 192273 and/or the high-galactic-latitude X-ray source 3U 1959-69.

Cash, W.↗

Development of Computational Environmental Microbiome Workflows for the Laboratory and the International Space Station

Identification of microorganisms in the spaceflight environment is critical for crew health risk assessment on the International Space Station (ISS). Since 2017, nanopore sequencing technology has been used to support thein situ identification of microbial species during spaceflight. Beginning in 2018, a culture-independent, swab-to-sequencer method was implemented onboard the ISS to provide a more thorough insight of the ISS microbiome. Eliminating microbial culture enables identification of difficult-to-culture organisms, reduces risks associated with potentially pathogenic cultures, and could significantly reduce the time from sample-to-answer. However, this molecular-based approach generates large metagenomic datasets that require substantial computational resources for analysis. To process nanopore-generated sequencing data, the JSC Microbiology Laboratory established a bioinformatics workflow on Amazon EC2 under the security guidance of the NASA Science Managed Cloud Environment (SMCE).This resource allows for the development, testing, and accessing of computational tools for processing large and complex datasets. The work described here will address the downlinking of data from the ISS, the automated pipeline developed to identify targeted bacterial and fungal organisms, and the time from sampling onboard to microbial identification. The pipelines have been enhanced to address high and low biomass samples using optimization based on sample source (air, water, or surface) and type of collection (filter, colony, or swab).The resulting microbiome data can be assessed beyond microbial identifications to gain understanding toward population changes over time, potential selective environmental pressures, and evaluating correlations with a wide range of additional data sets. Metagenome analysis pipelines in development could allow for simultaneous identification of microbial species, gene function, and gene pathways present in the environment. Beyond the ground processing, the developed analysis pipeline is currently deployed onboard the ISS to allow for near real-time assessments of the ISS microbiome. This study serves as a critical foundation for exploration missions, where rapid microbiome analyses will be required.

G. Marie Sharp↗

CSPlib

This computational singular perturbation library (CSPlib) software is useful for analysis of chemical kinetic systems. The code is used to analyze and describe the dynamical landscape underlying the time evolution of a chemical system. Given a database of state vectors, it allows the analysis of the source term and Jacobian matrix of the chemical system, the identification and decoupling of fast and slow processes, and the analysis of cause-and-effect relationships in the coupled system dynamics. Sandia National Laboratories is a multimission laboratory managed and operated by National Technology & Engineering Solutions of Sandia, LLC, a wholly owned subsidiary of Honeywell International Inc., for the U.S. Department of Energy’s National Nuclear Security Administration under contract DE-NA0003525. SAND2021-2391 O

Najm, HabibN.↗

Particle damage sources for fused silica optics and their mitigation on high energy laser systems

High energy laser systems are ultimately limited by laser-induced damage to their critical components. This is especially true of damage to critical fused silica optics, which grows rapidly upon exposure to additional laser pulses. Much progress has been made in eliminating damage precursors in as-processed fused silica optics (the advanced mitigation process, AMP3), and very high damage resistance has been demonstrated in laboratory studies. However, the full potential of these improvements has not yet been realized in actual laser systems. In this work, we explore the importance of additional damage sources–in particular, particle contamination–for fused silica optics fielded in a high-performance laser environment, the National Ignition Facility (NIF) laser system. We demonstrate that the most dangerous sources of particle contamination in a system-level environment are laser-driven particle sources. In the specific case of the NIF laser, we have identified the two important particle sources which account for nearly all the damage observed on AMP3 optics during full laser operation and present mitigations for these particle sources. Finally, with the elimination of these laser-driven particle sources, we demonstrate essentially damage free operation of AMP3 fused silica for ten large optics (a total of 12,000 cm 2 of beam area) for shots from 8.6 J/cm 2 to 9.5 J/cm 2 of 351 nm light (3 ns Gaussian pulse shapes). Potentially many other pulsed high energy laser systems have similar particle sources, and given the insight provided by this study, their identification and elimination should be possible. The mitigations demonstrated here are currently being employed for all large UV silica optics on the National Ignition Facility

36 MATERIALS SCIENCE↗