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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 847 records · Page 47

Bio-derived Fuel Blend Dilution of Marine Engine Oil and Imapct on Friction and Wear Behavior

To reduce the amount of petroleum-derived fuel used in vehicles and vessels powered by internal combustion engines, the addition of bio-derived fuel extenders is a common practice. Ethanol is perhaps the most common bio-derived fuel used for blending, and butanol is being evaluated as a promising alternative. The present study determined the fuel dilution rate of three lubricating oils (E0, E10, and i-B16) in a marine engine operating in on-water conditions with a start-and-stop cycle protocol. The level of fuel dilution increased with the number of cycles for all three fuels. The most dilution was observed with i-B16 fuel, and the least with E10 fuel. In all cases, fuel dilution substantially reduced the oil viscosity. The impacts of fuel dilution and the consequent viscosity reduction on the lubricating capability of the engine oil in terms of friction, wear, and scuffing prevention were evaluated by four different tests protocols. Although the fuel dilution of the engine oil had minimal effect on friction, because the test conditions were under the boundary lubrication regime, significant effects were observed on wear in many cases. Fuel dilution also was observed to reduce the load-carrying capacity of the engine oils in terms of scuffing load reduction.

Ajayi, Oyelayo O.↗

Surface water and groundwater FTICR-MS, NPOC, and TN from nine wetlands and three upland wells at the Tanglewood Biological Station, Alabama

This dataset supports a broader study examining wetland hydrobiogeochemical responses to flood disturbance and the subsequent impacts on watershed nutrient export. The study was designed following ICON (integrated, coordinated, open, and networked) principles. Samples were collected from nine wetlands and three upland wells at the Tanglewood Biological Station, Alabama in August 2024 and February 2025, during the dry and wet season, respectively. The contents include geochemistry (dissolved organic carbon measured as non-purgeable organic carbon; total dissolved nitrogen) and organic matter characterization (FTICR-MS). Related water level data from the same locations can be found at https://data.ess-dive.lbl.gov/view/doi:10.15485/2530253. Additional geochemistry will be published in a separate data package. For details on how to navigate this data package, see this infographic from the River Corridor SFA https://data.ess-dive.lbl.gov/portals/PNNLRiverCorridorSFA/About. In addition to a readme, this data package also includes a file-level metadata (FLMD) file that describes each file and a data dictionary (DD) that describes all column/row headers and variable definitions.This dataset is comprised of (1) a folder containing environmental context photos; (2) file-level metadata; (3) data dictionary; (4) field metadata; (5) readme; (6) international generic sample number (IGSN) mapping file; (7) the field protocol; and (8) a subfolder with sample data. The sample data subfolder contains (1) dissolved organic carbon (DOC, measured as non-purgeable organic carbon, NPOC) data and averages; (2) total nitrogen data and averages; (3) methods codes; and (4) a subfolder of 12 Tesla (12T) Fourier-transform ion cyclotron resonance mass spectrometry (FTICR-MS) data. All files are .csv, .pdf, .jpeg, or .jpg.

54 ENVIRONMENTAL SCIENCES↗

Northwest National Marine Renewable Energy Center

In 2008, the US Department of Energy’s (DOE) Wind and Water Power Program issued a funding opportunity announcement to establish university-led National Marine Renewable Energy Centers. Oregon State University and the University of Washington combined their capabilities in wave and tidal energy to establish the Northwest National Marine Renewable Energy Center, or NNMREC. NNMREC’s scope included research and testing in the following topic areas: • Advanced Wave Forecasting Technologies; • Device and Array Optimization; • Integrated and Standardized Test Facility Development; • Investigate the Compatibility of Marine Energy Technologies with Environment, Fisheries and other Marine Resources; • Increased Reliability and Survivability of Marine Energy Systems; • Collaboration/Optimization with Marine Renewable and Other Renewable Energy Resources. To support the last topic, the National Renewable Energy Laboratory (NREL) was brought onto the team, particularly to assist with testing protocols, grid integration, and testing instrumentation. NNMREC’s mission is to facilitate the development of marine energy technology, to inform regulatory and policy decisions, and to close key gaps in scientific understanding with a focus on workforce development. In this, NNMREC achieves DOE’s goals and objectives and remains aligned with the research and educational mission of universities. In 2012, DOE provided NNMREC an opportunity to propose an additional effort to begin work on a utility scale, grid connected wave energy test facility. That project, initially referred to as the Pacific Marine Energy Center, is now referred to as the Pacific Marine Energy Center South Energy Test Site (PMEC-SETS) and involves work directly toward establishing the facility, which will be in Newport Oregon, as well as supporting instrumentation for wave energy converter testing. This report contains a breakdown per subtask of the funded project. Under each subtask, the following are presented and discussed where appropriate: the initial objective or hypothesis; an overview of accomplishments and approaches used; any problems encountered or departures from planned methodology over the life of the project; impacts of the problems or rescoping of the project; how accomplishments compared with original project goals; and deliverables under the subtasks. Products and models developed under the award are also included.

16 TIDAL AND WAVE POWER↗

RoCE: Promising Technology for Ethernet as a High Performance Networking Fabric

Remote Direct Memory Access (RDMA) over Converged Ethernet (RoCE) has the potential to provide performance that rivals traditional high performance fabrics. If this potential proves out, significant impacts on system procurement decisions could follow. This work provides a series of small scale performance results which are used to compare and contrast the performance of RoCE-enabled Ethernet with TCP-based Ethernet and an HPC network. Additionally, a discussion of the maturity of RoCE firmware/software stacks and documentation is provided along with useful approaches for probing performance. A detailed description of two experimental setups known to have good RoCE performance is given, including step-by-step configuration and the exact hardware and software revisions employed. At small scales, RoCE is found to have significant performance advantages over "out-of-the-box" TCP protocols and is competitive with state-of-the-art high performance networks. Further examination of RoCE using a wider array of benchmarks and at greater scale is warranted.

97 MATHEMATICS AND COMPUTING↗

Visualizing Solution Structure at Solid-Liquid Interfaces using Three-Dimensional Fast Force Mapping

Amongst the challenges for a variety of research fields are the visualization of solid-liquid interfaces and understanding how they are affected by the solution conditions such as ion concentrations, pH, ligands, and trace additives, as well as the underlying crystallography and chemistry. Here, in this context, three-dimensional fast force mapping (3D FFM) has emerged as a promising tool for investigating solution structure at interfaces. This capability is based on atomic force microscopy (AFM) and allows the direct visualization of interfacial regions in three spatial dimensions with sub-nanometer resolution. Here we provide a detailed description of the experimental protocol for acquiring 3D FFM data. The main considerations for optimizing the operating parameters depending on the sample and application are discussed. Moreover, the basic methods for data processing and analysis are discussed, including the transformation of the measured instrument observables into tip-sample force maps that can be linked to the local solution structure. Finally, we shed light on some of the outstanding questions related to 3D FFM data interpretation and how this technique can become a central tool in the repertoire of surface science.

Nakouzi, Elias↗

A Complex-Geometry Validation Experiment for Advanced Neutron Transport Codes

The Idaho National Laboratory (INL) has initiated a focused effort to upgrade legacy computational reactor physics software tools and protocols used for support of core fuel management and experiment management in the Advanced Test Reactor (ATR) and its companion critical facility (ATRC) at the INL.. This will be accomplished through the introduction of modern high-fidelity computational software and protocols, with appropriate new Verification and Validation (V&V) protocols, over the next 12-18 months. Stochastic and deterministic transport theory based reactor physics codes and nuclear data packages that support this effort include MCNP5[1], SCALE/KENO6[2], HELIOS[3], SCALE/NEWT[2], and ATTILA[4]. Furthermore, a capability for sensitivity analysis and uncertainty quantification based on the TSUNAMI[5] system has also been implemented. Finally, we are also evaluating the Serpent[6] and MC21[7] codes, as additional verification tools in the near term as well as for possible applications to full three-dimensional Monte Carlo based fuel management modeling in the longer term. On the experimental side, several new benchmark-quality code validation measurements based on neutron activation spectrometry have been conducted using the ATRC. Results for the first four experiments, focused on neutron spectrum measurements within the Northwest Large In-Pile Tube (NW LIPT) and in the core fuel elements surrounding the NW LIPT and the diametrically opposite Southeast IPT have been reported [8,9]. A fifth, very recent, experiment focused on detailed measurements of the element-to-element core power distribution is summarized here and examples of the use of the measured data for validation of corresponding MCNP5, HELIOS, NEWT, and Serpent computational models using modern least-square adjustment methods are provided.

97 MATHEMATICS AND COMPUTING↗

Northwest National Marine Renewable Energy Center

In 2008, the US Department of Energy’s (DOE) Wind and Water Power Program issued a funding opportunity announcement to establish university-led National Marine Renewable Energy Centers. Oregon State University and the University of Washington combined their capabilities in wave and tidal energy to establish the Northwest National Marine Renewable Energy Center, or NNMREC. NNMREC’s scope included research and testing in the following topic areas: • Advanced Wave Forecasting Technologies; • Device and Array Optimization; • Integrated and Standardized Test Facility Development; • Investigate the Compatibility of Marine Energy Technologies with Environment, Fisheries and other Marine Resources; • Increased Reliability and Survivability of Marine Energy Systems; • Collaboration/Optimization with Marine Renewable and Other Renewable Energy Resources. To support the last topic, the National Renewable Energy Laboratory (NREL) was brought onto the team, particularly to assist with testing protocols, grid integration, and testing instrumentation. NNMREC’s mission is to facilitate the development of marine energy technology, to inform regulatory and policy decisions, and to close key gaps in scientific understanding with a focus on workforce development. In this, NNMREC achieves DOE’s goals and objectives and remains aligned with the research and educational mission of universities. In 2012, DOE provided NNMREC an opportunity to propose an additional effort to begin work on a utility scale, grid connected wave energy test facility. That project, initially referred to as the Pacific Marine Energy Center, is now referred to as the Pacific Marine Energy Center South Energy Test Site (PMEC-SETS) and involves work directly toward establishing the facility, which will be in Newport Oregon, as well as supporting instrumentation for wave energy converter testing. This report contains a breakdown per subtask of the funded project. Under each subtask, the following are presented and discussed where appropriate: the initial objective or hypothesis; an overview of accomplishments and approaches used; any problems encountered or departures from planned methodology over the life of the project; impacts of the problems or rescoping of the project; how accomplishments compared with original project goals; and deliverables under the subtasks. Products and models developed under the award are also included.

16 TIDAL AND WAVE POWER↗

Myocardial perfusion imaging in women for the evaluation of stable ischemic heart disease—state-of-the-evidence and clinical recommendations

This document from the American Society of Nuclear Cardiology represents an updated consensus statement on the evidence base of stress myocardial perfusion imaging (MPI), emphasizing new developments in single-photon emission tomography (SPECT) and positron emission tomography (PET) in the clinical evaluation of women presenting with symptoms of stable ischemic heart disease (SIHD). The clinical evaluation of symptomatic women is challenging due to their varying clinical presentation, clinical risk factor burden, high degree of comorbidity, and increased risk of major ischemic heart disease events. Evidence is substantial that both SPECT and PET MPI effectively risk stratify women with SIHD. The addition of coronary flow reserve (CFR) with PET improves risk detection, including for women with nonobstructive coronary artery disease and coronary microvascular dysfunction. With the advent of PET with computed tomography (CT), multiparametric imaging approaches may enable integration of MPI and CFR with CT visualization of anatomical atherosclerotic plaque to uniquely identify at-risk women. Radiation dose-reduction strategies, including the use of ultra-low-dose protocols involving stress-only imaging, solid-state detector SPECT, and PET, should be uniformly applied whenever possible to all women undergoing MPI. Appropriate candidate selection for stress MPI and for post-MPI indications for guideline-directed medical therapy and/or invasive coronary angiography are discussed in this statement. The critical need for randomized and comparative trial data in female patients is also emphasized.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

Proximity-Induced Exchange Interaction: A New Pathway for Quantum Sensing Using Spin Centers in Hexagonal Boron Nitride

Defects in hexagonal boron nitride (hBN), a two-dimensional van der Waals material, have attracted a great deal of interest because of its potential in various quantum applications. Due to hBN’s two-dimensional nature, the spin center in hBN can be engineered in the proximity of the target material, providing advantages over its three-dimensional counterparts, such as the nitrogen-vacancy center in diamond. Here, in this work, we propose a novel quantum sensing protocol driven by exchange interaction between the spin center in hBN and the underlying magnetic substrate induced by the magnetic proximity effect. By first-principles calculation, we demonstrate that the induced exchange interaction dominates over the dipole–dipole interaction by orders of magnitude when in the proximity. The interaction remains antiferromagnetic across all stacking configurations between the spin center in hBN and the target van der Waals magnets. Additionally, we explored the scaling behavior of the exchange field as a function of the spatial separation between the spin center and the targets.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

High-throughput small-angle X-ray scattering reveals effective structure factor transitions linked to high-concentration antibody viscosity

High-concentration monoclonal antibody (mAb) formulations are often constrained by elevated viscosity, largely driven by protein–protein interactions, which complicates manufacturing and limits subcutaneous delivery. Early viscosity risk assessment is essential during discovery, yet traditional measurements require large sample volumes, and lack high-throughput capability. Here, we develop a high-throughput small-angle X-ray scattering (SAXS) protocol to detect mAb self-association at dilute concentrations, enabling early predictive insights into high-concentration viscosity. Synchrotron SAXS measurements were conducted for 21 mAbs formulated in a histidine buffer at pH 6.0. An initial subset of 10 mAbs analyzed across 1–150 mg/mL revealed that effective structure factor transitions in the low-q region, indicative of interparticle interactions, consistently emerged below 25 mg/mL. Subsequently, 11 additional mAbs were analyzed at 1–25 mg/mL using automated liquid handling and flow cells to enable high-throughput screening. High-viscosity mAbs exhibited detectable low-q upturns at concentrations ≤10 mg/mL, whereas low-viscosity mAbs showed downturns. A classification criterion based on effective structure factor transitions accurately classified all high- and low-viscosity mAbs at 150 mg/mL, offering a scalable, sample-efficient alternative to conventional methods. These results extend recent findings on the concentration-dependent sensitivity of SAXS to short-range attractions, demonstrating that they can emerge at lower concentrations than previously reported. This study presents the most comprehensive and diverse SAXS dataset for mAbs reported to date within a single formulation, providing a valuable resource for developing and validating coarse-grained models that can more accurately capture intermolecular interactions governing high-concentration solution behavior, thereby enabling rational antibody engineering and improved developability.

36 MATERIALS SCIENCE↗

Using the CYBER-Champ Model to Determine Cyber Competencies and Role Alignment

Cybersecurity roles, tasks, and skills are seen by many organizations as nonessential, abstract, or complicated. Although standards are in place, such as the National Institute of Standards and Technology (NIST) 800-181 document titled “Workforce Framework for Cybersecurity (NICE Framework)” available since September 2012, companies are still showing security vulnerabilities in their cyber networks (Hatzes, 2020). Barriers towards creating a cyber-ready workforce are not always due to a lack of resources, but often caused by organizational structure. The need for cyber-cognizant job postings, improved communication between Operational Technology (OT) and Information Technology (IT) employees, increases in staffing and funding for cyber teams, and better communication of standards and training can all contribute to increasing an organization’s cyber resilience. Cybersecurity Competency Health and Maturity Progression model (CYBER-CHAMP) is a model aimed at evaluating an organization’s structure and individual employee’s cyber knowledge and helps develop a plan to reach competency. This model was used to engage with organizations to promote proper cyber protocols and policies. The aim of this paper is to answer if it is possible for an organization to build a cyber-ready workforce by providing education and training options for current employees and prepare the future workforce to be ready on day one of employment. Both open source and firsthand interviews with organizations were used to conduct the research contained in this document. Further research may include additional development to the CYBER-CHAMP model and its delivery platform.

99 GENERAL AND MISCELLANEOUS↗

Chromosome-Specific DNA Repeats: Rapid Identification in Silico and Validation Using Fluorescence in Situ Hybridization

Chromosome enumeration in interphase and metaphase cells using fluorescence in situ hybridization (FISH) is an established procedure for the rapid and accurate cytogenetic analysis of cell nuclei and polar bodies, the unambiguous gender determination, as well as the definition of tumor-specific signatures. Present bottlenecks in the procedure are a limited number of commercial, non-isotopically labeled probes that can be combined in multiplex FISH assays and the relatively high price and effort to develop additional probes. We describe a streamlined approach for rapid probe definition, synthesis and validation, which is based on the analysis of publicly available DNA sequence information, also known as “database mining”. Examples of probe preparation for the human gonosomes and chromosome 16 as a selected autosome outline the probe selection strategy, define a timeline for expedited probe production and compare this novel selection strategy to more conventional probe cloning protocols.

59 BASIC BIOLOGICAL SCIENCES↗

Metrics for Intercomparison of Remapping Algorithms (MIRA) protocol applied to Earth system models

Abstract. Strongly coupled nonlinear phenomena such as those described by Earth system models (ESMs) are composed of multiple component models with independent mesh topologies and scalable numerical solvers. A common operation in ESMs is to remap or interpolate component solution fields defined on their computational mesh to another mesh with a different combinatorial structure and decomposition, e.g., from the atmosphere to the ocean, during the temporal integration of the coupled system. Several remapping schemes are currently in use or available for ESMs. However, a unified approach to compare the properties of these different schemes has not been attempted previously. We present a rigorous methodology for the evaluation and intercomparison of remapping methods through an independently implemented suite of metrics that measure the ability of a method to adhere to constraints such as grid independence, monotonicity, global conservation, and local extrema or feature preservation. A comprehensive set of numerical evaluations is conducted based on a progression of scalar fields from idealized and smooth to more general climate data with strong discontinuities and strict bounds. We examine four remapping algorithms with distinct design approaches, namely ESMF Regrid (Hill et al., 2004), TempestRemap (Ullrich and Taylor, 2015), generalized moving least squares (GMLS) (Trask and Kuberry, 2020) with post-processing filters, and WLS-ENOR (Li et al., 2020). By repeated iterative application of the high-order remapping methods to the test fields, we verify the accuracy of each scheme in terms of their observed convergence order for smooth data and determine the bounded error propagation using challenging, realistic field data on both uniform and regionally refined mesh cases. In addition to retaining high-order accuracy under idealized conditions, the methods also demonstrate robust remapping performance when dealing with non-smooth data. There is a failure to maintain monotonicity in the traditional L2-minimization approaches used in ESMF and TempestRemap, in contrast to stable recovery through nonlinear filters used in both meshless GMLS and hybrid mesh-based WLS-ENOR schemes. Local feature preservation analysis indicates that high-order methods perform better than low-order dissipative schemes for all test cases. The behavior of these remappers remains consistent when applied on regionally refined meshes, indicating mesh-invariant implementations. The MIRA intercomparison protocol proposed in this paper and the detailed comparison of the four algorithms demonstrate that the new schemes, namely GMLS and WLS-ENOR, are competitive compared to standard conservative minimization methods requiring computation of mesh intersections. The work presented in this paper provides a foundation that can be extended to include complex field definitions, realistic mesh topologies, and spectral element discretizations, thereby allowing for a more complete analysis of production-ready remapping packages.

58 GEOSCIENCES↗

Multicenter Phase 2 Study of Cisplatin and 5-Fluorouracil With Concurrent Radiation Therapy as an Organ Preservation Approach in Patients With Squamous Cell Carcinoma of the Cervical Esophagus

Purpose: To clarify, in a multicenter, single-arm, phase 2 study (UMIN Clinical Trials Registry no. UMIN000001439), the clinical profile of chemoradiotherapy (CRT) for cervical esophageal cancer. Patients and Methods: Patients with operable cervical esophageal cancer, excluding candidates for endoscopic resection, were enrolled. Protocol treatment consisted of CRT and adjuvant chemotherapy (CT). First, patients received concurrent CRT with 5-fluorouracil (5-FU) plus cisplatin (CDDP). Chemotherapy consisted of 5-FU at 700 mg/m{sup 2} intravenous on days 1 to 4 and CDDP at 70 mg/m{sup 2} intravenous on day 1, repeated every 4 weeks for 2 cycles. Radiation therapy consisted of 60 Gy in 30 fractions. After completion of CRT, 2 additional cycles of CT with 5-FU (800 mg/m{sup 2}, days 1-5) and CDDP (80 mg/m{sup 2}, day 1) were repeated at a 4-week interval. The primary endpoint was 3-year overall survival. Results: Thirty patients were enrolled across 8 institutions in Japan, consisting of 26 men and 4 women with a median age of 64.5 years (range, 50-75 years). No grade 4 hematologic toxicity was seen in the CRT phase, and 1 grade 4 thrombocytopenia was seen in the CT phase. Grade 3 nonhematologic acute toxicities in the CRT phase were nausea (10%), mucositis (13.3%), and dysphagia (13.3%). No treatment-related death in either phase occurred. Overall complete response rate was 73%, and 3-year overall and laryngectomy-free survival were 66.5% and 52.5%, respectively. Regarding T4 disease, 3-year overall and laryngectomy-free survival were 58.3% and 38.5%, respectively. Conclusions: This study, the first prospective study for cervical esophageal cancer, showed that CRT has sufficient efficacy and safety for use as an alternative to surgery for these patients.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

An extrapolation method for strain ranges and hold times in developing the EPP+SMT creep-fatigue design curves for Alloy 617

Experimental and numerical studies in developing the integrated Elastic–Perfectly Plastic (EPP) plus Simplified Model Test (SMT) design methodology, referred to as the EPP+SMT method, continued in FY2022. This report focuses on the methods for extrapolating the EPP+SMT creep-fatigue (CF) design curves at long hold times and low strain ranges. In this study, the available CF failure data on Alloy 617 at 950°C were analyzed to determine a set of CF failure criteria. At very low strain ranges and long hold times, CF failure data are not accessible by experiments because of the extraordinarily long test durations and the inability of the test machines to accurately control these small strain ranges. A CF experimental approach with the concept of block-strain range CF testing protocol was developed. Tests using this protocol were conducted to generate the needed information for calibrating material parameters of the numerical material models. The Time Fraction based method and Dissipated Energy method were used to extrapolate the CF life curves to low strain ranges and long hold times. Based on the new experimental approach and CF life prediction methods, the CF life curves with various hold times were developed for Alloy 617 at 950°C. In addition, an experiment was designed and is being performed to verify the predicted CF curves at 950°C. The extrapolation procedure will be applied at lower temperatures to complete the development of the EPP+SMT CF design curves for Alloy 617 in F2023.

36 MATERIALS SCIENCE↗

Assessing the climate impact of an improved volcanic sulfate aerosol representation in E3SM

Accurately simulating historical surface temperature variations is essential for evaluating climate models, yet many struggle to reproduce the mid-20th-century temperature trends associated with significant volcanic eruptions. This study examines the impact of volcanic sulfate aerosol representation on these biases using the Energy Exascale Earth System Model (E3SM). The standard CMIP6 protocol prescribes volcanic forcing through radiative perturbations, omitting volcanic aerosol–cloud interactions (VACIs). Here, we implement an emission-based approach with an updated volcanic eruption inventory that directly incorporates volcanic sulfur dioxide (SO 2 ) emissions, enabling a more process-based representation of volcanic forcing. This approach leads to improved surface temperature variability and a modest reduction in cold biases between 1940 and 1980 compared to the CMIP6 setup. Additionally, we assess cloud property responses to a more realistic volcanic sulfate aerosol representation, which weakens cloud-induced cooling during periods of lower volcanic activity. However, despite these refinements, a significant temperature cold bias remains, indicating that further improvements in atmospheric chemistry, aerosol microphysics, cloud processes, and model parameterizations are needed to fully resolve this issue in E3SM.

54 ENVIRONMENTAL SCIENCES↗

Theoretical and Experimental Thermal Performance Analysis of Complex Thermal Storage Membrane Containing Bio-Based Phase Change Material (PCM)

Since 2000, an ORNL research team has been testing different configurations of PCM-enhanced building envelop components to be used in residential and commercial buildings. During 2009, a novel type of thermal storage membrane was evaluated for building envelope applications. Bio-based PCM was encapsulated between two layers of heavy-duty plastic film forming a complex array of small PCM cells. Today, a large group of PCM products are packaged in such complex PCM containers or foils containing arrays of PCM pouches of different shapes and sizes. The transient characteristics of PCM-enhanced building envelope materials depend on the quality and amount of PCM, which is very often difficult to estimate because of the complex geometry of many PCM heat sinks. The only widely used small-scale analysis method used to evaluate the dynamic characteristics of PCM-enhanced building products is the differential scanning calorimeter (DSC). Unfortunately, this method requires relatively uniform, and very small, specimens of the material. However, in numerous building thermal storage applications, PCM products are not uniformly distributed across the surface area, making the results of traditional DSC measurements unrealistic for these products. In addition, most of the PCM-enhanced building products contain blends of PCM with fire retardants and chemical stabilizers. This combination of non-uniform distribution and non-homogenous composition make it nearly impossible to select a representative small specimen suitable for DSC tests. Recognizing these DSC limitations, ORNL developed a new methodology for performing dynamic heat flow analysis of complex PCM-enhanced building materials. An experimental analytical protocol to analyze the dynamic characteristics of PCM thermal storage makes use of larger specimens in a conventional heat-flow meter apparatus, and combines these experimental measurements with three-dimensional (3-D) finite-difference modeling and whole building energy simulations. Based on these dynamic tests and modeling, ORNL researchers then developed a simplified one-dimensional (1-D) model of the PCM-enhanced building component that can be easily used in whole-building simulations. This paper describes this experimental-analytical methodology as used in the analysis of an insulation assembly containing a complex array of PCM pouches. Based on the presented short example of whole building energy analysis, this paper describes step-by-step how energy simulation results can be used for optimization of PCM-enhanced building envelopes. Limited results of whole building energy simulations using the EnergyPlus program are presented as well.

25 ENERGY STORAGE↗

Differential Motion Between Mediastinal Lymph Nodes and Primary Tumor in Radically Irradiated Lung Cancer Patients

Purpose/Objective: In patients with locally advanced lung cancer, planning target volume margins for mediastinal lymph nodes and tumor after a correction protocol based on bony anatomy registration typically range from 1 to 1.5 cm. Detailed information about lymph node motion variability and differential motion with the primary tumor, however, is lacking from large series. In this study, lymph node and tumor position variability were analyzed in detail and correlated to the main carina to evaluate possible margin reduction. Methods and Materials: Small gold fiducial markers (0.35 × 5 mm) were placed in the mediastinal lymph nodes of 51 patients with non-small cell lung cancer during routine diagnostic esophageal or bronchial endoscopic ultrasonography. Four-dimensional (4D) planning computed tomographic (CT) and daily 4D cone beam (CB) CT scans were acquired before and during radical radiation therapy (66 Gy in 24 fractions). Each CBCT was registered in 3-dimensions (bony anatomy) and 4D (tumor, marker, and carina) to the planning CT scan. Subsequently, systematic and random residual misalignments of the time-averaged lymph node and tumor position relative to the bony anatomy and carina were determined. Additionally, tumor and lymph node respiratory amplitude variability was quantified. Finally, required margins were quantified by use of a recipe for dual targets. Results: Relative to the bony anatomy, systematic and random errors ranged from 0.16 to 0.32 cm for the markers and from 0.15 to 0.33 cm for the tumor, but despite similar ranges there was limited correlation (0.17-0.71) owing to differential motion. A large variability in lymph node amplitude between patients was observed, with an average motion of 0.56 cm in the cranial-caudal direction. Margins could be reduced by 10% (left-right), 27% (cranial-caudal), and 10% (anteroposterior) for the lymph nodes and −2%, 15%, and 7% for the tumor if an online carina registration protocol replaced a protocol based on bony anatomy registration. Conclusions: Detailed analysis revealed considerable lymph node position variability, differential motion, and respiratory motion. Planning target volume margins can be reduced up to 27% in lung cancer patients when the carina registration replaces bony anatomy registration.

62 RADIOLOGY AND NUCLEAR MEDICINE↗