Limitations in current acetylcholinesterase structure based design of oxime antidotes for organophosphate poisoning
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The characteristics of semiconductor chip modulators providing the angular deflection of a laser beam due to all-electric modulation of the optical characteristics of a semiconductor heterostructure are theoretically studied. Designs for quantum-confined semiconductor waveguide heterostructures with a distributed Bragg reflector integrated on the heterostructure surface are developed. The design of a waveguide structure including 20 periods of coupled asymmetric quantum wells, which provide an optical confinement factor of the waveguide mode of 20%, and an optimized doping profile allowing a uniform electric-field distribution to be maintained in the quantum-well region in the entire range of operating voltages are proposed. In this waveguide structure, the change in the refractive index due to the quantum-confined Stark effect reaches 0.086 when the control signal changes from 0 to 6 V. It is shown that the spatial (angular) scanning of the laser beam emitted from the surface of a distributed Bragg mirror with a divergence of less than 0.1° in the range of 1°–2° is feasible for the proposed waveguide structure design.
Low-temperature electrochemical ammonia synthesis with heterogeneous catalysts suffers from extremely low Faradaic efficiencies (< 1%). The hydrogen evolution reaction (HER) is predicted and experimentally demonstrated to outcompete the nitrogen reduction reaction (N2RR). Meanwhile, the nitrogenase enzymes found in nature enable selective N2RR at Fe/Mo metal centers. Montoya and co-authors suggest that a successful transition metal N2RR catalyst will deviate from or completely circumvent current linear scaling relationships. We propose an approach where short-chain peptides (3-20 amino acids) will be used to control the local surface environment of catalysts. This peptide-based design strategy will be used to overcome HER selectivity and the limitations of *NxHy adsorbate scaling.
This report surveys current creep-fatigue design and fitness-for-service assessment procedures, with a particular focus on environmental effects and creep-fatigue cracking near weldments. Included in this assessment are the American Society of Mechanical Engineers Boiler and Pressure Vessel Code Section III, Division 5, the British R5 standard, the French RCC-MRx design code, the ITER Structural Design Criteria, and the API-579/ASME FFS-1 fitness-for-service rules for petrochemical components. The focus of this review is to identify gaps in the available methods that could prevent regulators from evaluating future high temperature reactor designs. The report makes recommendations, where appropriate, on actions that could be taken to fill these gaps by either providing adequate assessment procedures for creep-fatigue damage in harsh environments or by evaluating strategies vendors could use to mitigate regulatory concerns with creep-fatigue damage in high temperature reactor components.
Splice plate with mechanical joint is separated by expanding gases of a mild detonating fuse. The gas pressures of the low-yield explosive eliminate component fragmentation and achieve excellent control of the separation line.
Dynamic response in current structural problems using computer programs and coordinate transformations
The results of an analytical study are presented on the use of boron polyimide filamentary composite material for the purpose of increasing the flutter speed of a simple titanium full depth sandwich wing structure designed for strength. The results clearly demonstrate that selective reinforcement of wing surfaces, using judiciously placed filamentary composites, promises sizable mass savings in the design of advanced aircraft structures.
A comprehensive experimental and analytical evaluation of the tensor polynomial failure criterion was undertaken to determine its capability for predicting the ultimate strength of a composite limina subject to a plane stress state. Results are presented demonstrating that a quadratic formulation is too conservative and a cubic representation is required. Strength comparisons with test data derived from glass/epoxy and graphite/epoxy tubular specimens are also provided to validate the cubic strength criterion. Environmental effects including ambient temperature, exposure to vacuum, length of post-cure time, and rate of cool down were also investigated. Behavior changes associated with polymer (epoxy) matrix composites were determined in terms of variations in stiffness and tensile strength.
Elastic wave propagation and attenuation in a model fiber matrix was investigated. Damping characteristics in graphite epoxy composite materials were measured. A sound transmission test facility suitable to incorporate into NASA Ames wind tunnel for measurement of transmission loss due to sound generation in boundary layers was constructed. Measurement of transmission loss of graphite epoxy composite panels was also included.
The design of launch pad structures is critically dependent upon the stresses imposed by the acoustical pressure field generated by the rocket engines during launch. The purpose of this effort is to better describe the acoustical field in the immediate launch area. Since the problem is not analytically tractable, empirical modeling will be employed so that useful results may be obtained for structural design purposes. The plume of the rocket is considered to be a volumetric acoustic source, and is broken down into incremental contributing volumes. A computer program has been written to sum all the contributions to find the total sound pressure level at an arbitrary point. A constant density source is initially assumed and the acoustic field evaluated for several cases to verify the correct operation of the program.
This presentation will discuss the development of a NASA Geometry Exchange Specification for transferring aerodynamic surface geometry between LeRC systems and grid generation software used for computational fluid dynamics research. The proposed specification is based on a subset of the Initial Graphics Exchange Specification (IGES). The presentation will include discussion of how the NASA-IGES standard will accommodate improved computer aided design inspection methods and reverse engineering techniques currently being developed. The presentation is in viewgraph format.
Report presents theoretical foundations of some of algorithms implemented by JPL-IDEAS computer program.
This article describes research related to sampling techniques for establishing linear relations between land surface parameters and remotely-sensed data. Predictive relations are estimated between percentage tree cover in a savanna environment and a normalized difference vegetation index (NDVI) derived from the Thematic Mapper sensor. Spatial autocorrelation in original measurements and regression residuals is examined using semi-variogram analysis at several spatial resolutions. Sampling schemes are then tested to examine the effects of autocorrelation on predictive linear models in cases of small sample sizes. Regression models between image and ground data are affected by the spatial resolution of analysis. Reducing the influence of spatial autocorrelation by enforcing minimum distances between samples may also improve empirical models which relate ground parameters to satellite data.
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The objective of this study is to apply the integrated design methodology to the mature GOES-1 spacecraft design, and to assess the possible advantages to be gained using this approach over the conventional sequential design approach used for the current design. In the process, the development of this technology into a tool that can be utilized for future near-term spacecraft designs is emphasized.