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NASA NTRS2015

Oxidative Stress and Autophagy Responses of Osteocytes Exposed to Spaceflight-like Radiation.

Weightlessness and radiation, two of the unique elements of the space environment, causes a profound decrement in bone mass that mimics aging. This bone loss is thought to result from increased activity of bone-resorbing osteoclasts and functional changes in bone-forming osteoblasts, cells that give rise to mature osteocytes. Our current understanding of the signaling factors and mechanisms underlying bone loss is incomplete. However, it is known that oxidative stress, characterized by the excess production of free radicals, is elevated during radiation exposure. The goals of this study is to examine the response of osteocytes to spaceflight-like radiation and to identify signaling processes that may be targeted to mitigate bone loss in scenarios of space exploration, earth-based radiotherapy and accidental radiation exposure. We hypothesize that (1) oxidative stress, as induced by radiation, decreases osteocyte survival and increases pro-osteoclastogenic signals and that (2) autophagy is one of the key cellular defenses against oxidative stress. Autophagy is the process by which cellular components including organelles and proteins are broken down and recycled. To test our hypothesis, we exposed the osteocyte-like cell line, MLO-Y4, to 0.5, 1, and 2 Gy of simulated space radiation (Iron-56 radiation at 600 MeV/n) and assessed cell numbers, cell growth-associated molecules as well as markers of autophagy and oxidative stress at various time points post-irradiation. We observed a reduction in cell numbers in the groups exposed to 1 and 2 Gy of Iron-56 radiation. Collectively, flow cytometry and gene expression analysis revealed that radiation caused a shift in cell cycle distribution consistent with growth arrest. Compared to sham-treatment, 2 Gy of Iron-56 increased FoxO3, SOD1, and RANKL gene expression yet unexpectedly decreased LC3B-II protein levels at 4 and 24 hours post-IR. Taken together, these findings suggest that simulated space radiation invoke antioxidant, pro-osteoclastogenic, and growth arrest responses in osteocytes. The implications of reduced autophagy flux at the time points examined remain to be elucidated.

Biological Sciences↗

NASA NTRSDate not supplied

Observations of Southeast Asian Biomass Burning and Urban Trace Gas Enhancement Ratios: Insights into Regional Air Quality and Aerosol Composition

Southeast Asian biomass burning is a major pollutant source that contributes to poor air quality throughout the region. Thus, understanding these emissions is critical for predicting and mitigating their health impacts. While many studies have reported ground-based and satellite measurements, airborne measurements at a regional scale capable of tying the two together have not been common. The 2019 Cloud, Aerosol and Monsoon Processes Philippines Experiment (CAMP2Ex) field project examined Southeast Asian regional sources and their effects on aerosol/cloud interactions using a combination of airborne, shipboard, and ground-based measurements. These flights sampled a variety of airmass sources over the Philippine, South China, and Sulu seas during both the southwest monsoon and monsoon transition periods. Measurements during CAMP2Ex provide a unique opportunity to investigate how these transported and local emissions affected air quality trends and airmass chemical composition. We present correlated airborne in situ enhancement ratios of CH4 to CO, using them to identify source regimes of either high urban or biomass burning influence as well as urban regimes with different emission factors. Combined with backtrajectory analysis using HYSPLIT, source regimes were examined for differences in ozone, reactive nitrogen, and aerosol chemical composition. While observed O3/CO enhancement ratios remain constant for differing urban source regimes, NOy/CO ratios varied across these regimes. For biomass burning sources, O3/CO enhancement ratios are observed to be lower than previously reported by measurements in the region.

Joshua P Digangi↗

DOE OSTI2020

Crystal structure of a guanine nucleotide exchange factor encoded by the scrub typhus pathogen Orientia tsutsugamushi

Rho family GTPases regulate an array of cellular processes and are often modulated by pathogens to promote infection. In this work, we identify a cryptic guanine nucleotide exchange factor (GEF) domain in the OtDUB protein encoded by the pathogenic bacterium Orientia tsutsugamushi. A proteomics-based OtDUB interaction screen identified numerous potential host interactors, including the Rho GTPases Rac1 and Cdc42. We discovered a domain in OtDUB with Rac1/Cdc42 GEF activity (OtDUB GEF ), with higher activity toward Rac1 in vitro. While this GEF bears no obvious sequence similarity to known GEFs, crystal structures of OtDUB GEF alone (3.0 Å) and complexed with Rac1 (1.7 Å) reveal striking convergent evolution, with a unique topology, on a V-shaped bacterial GEF fold shared with other bacterial GEF domains. Structure-guided mutational analyses identified residues critical for activity and a mechanism for nucleotide displacement. Ectopic expression of OtDUB activates Rac1 preferentially in cells, and expression of the OtDUBGEF alone alters cell morphology. Cumulatively, this work reveals a bacterial GEF within the multifunctional OtDUB that co-opts host Rac1 signaling to induce changes in cytoskeletal structure.

59 BASIC BIOLOGICAL SCIENCES↗

DOE OSTI2020

Spatial and temporal variation in nest temperatures forecasts sex ratio skews in a crocodilian with environmental sex determination

Species displaying temperature-dependent sex determination (TSD) are especially vulnerable to the effects of a rapidly changing global climate due to their profound sensitivity to thermal cues during development. Predicting the consequences of climate change for these species, including skewed offspring sex ratios, depends on understanding how climatic factors interface with features of maternal nesting behaviour to shape the developmental environment. Here, we measure thermal profiles in 86 nests at two geographically distinct sites in the northern and southern regions of the American alligator's ( Alligator mississippiensis ) geographical range, and examine the influence of both climatic factors and maternally driven nest characteristics on nest temperature variation. Changes in daily maximum air temperatures drive annual trends in nest temperatures, while variation in individual nest temperatures is also related to local habitat factors and microclimate characteristics. Without any compensatory nesting behaviours, nest temperatures are projected to increase by 1.6–3.7°C by the year 2100, and these changes are predicted to have dramatic consequences for offspring sex ratios. Exact sex ratio outcomes vary widely depending on site and emission scenario as a function of the unique temperature-by-sex reaction norm exhibited by all crocodilians. By revealing the ecological drivers of nest temperature variation in the American alligator, this study provides important insights into the potential consequences of climate change for crocodilian species, many of which are already threatened by extinction.

Environmental Sciences & Ecology↗

DOE OSTI2023

Soot Formation and Ignition Characteristics of Ethanol/Gasoline Blends in a Rapid Compression Machine

With the ever-increasing demand for sustainable energy, alcohol fuels have garnered interest for use in heavy duty engines. The significant infrastructure for ethanol production and blending of ethanol with gasoline make these fuels/fuel blends desirable candidates. However, development of heavy duty engine technology that is capable of burning alcohol fuels while retaining the advantages of traditional diesel combustion requires an improved understanding of the soot formation for these fuels under conditions relevant to mixing-controlled combustion. This work uses an extinction diagnostic to study the sooting tendency of ethanol and gasoline/ethanol blends ranging from E10 to E98 during ignition in a homogeneous environment. Experiments were conducted in a rapid compression machine (RCM) for compressed conditions of 20 ± 1 bar and an approximately constant temperature (± 10K) which was unique for each fuel. For a given soot volume fraction, a linear relationship was observed between ethanol content and the equivalence ratio in which that soot volume fraction was formed. Accounting for the oxygenated nature of ethanol, E85 and E98 fuels produced similar amounts of soot at a given Φ ox, , suggesting other factors outside of fuel oxygen content, such as fuel morphology, impact soot formation. Ignition delay data is reported for compressed pressures of 20 ± 1 bar and compressed temperatures ranging from 633 – 670 K for E10 and 771 – 789 K for E98. Varying pressures for E10 and E98 at conditions producing similar soot volume fractions demonstrated a linear dependence of soot formation on pressure, regardless of if the pressure considered was at top dead center or peak combustion pressure. Furthermore, the data gleaned from this work will be used to select soot models and chemical kinetic mechanisms for RCM simulations to ultimately model heavy duty engine technology with the studied fuels.

33 ADVANCED PROPULSION SYSTEMS↗

NASA NTRS1975

Semiperiodic variations in CO2 abundance on Venus

Tests of the uniqueness of periodicity in the strength of the P branch (P2-P38) of the 8689 A CO2 band on Venus are described. It was found that the observed 4-day periodicity was not unique. The periodicity indicated an increasing asymmetry between the northern and southern hemispheres with approach to inferior conjunction or with increasing phase angle. When the slit positions of the various scans were referred to the planet or atmospheric equator rather than to the intensity equator, at inferior conjunction, the slit positions having a factor of two greater CO2 abundance or line strength were over the polar latitudes of the atmosphere. Similarly, the lower-abundance slit positions were over the equatorial latitudes of the atmosphere. It is thus concluded that the level of line formation must be lower over polar latitudes than over equatorial regions.

Barker, E. S.↗

NASA NTRS1992

Protein crystal growth (5-IML-1)

Proteins (enzymes, hormones, immunoglobulins) account for 50 pct. or more of the dry weight of most living systems. A detailed understanding of the structural makeup of a protein is essential to any systematic research pertaining to it. Most macromolecules are extremely difficult to crystallize, and many otherwise exciting projects have terminated at the crystal growth stage. In principle, there are several aspects of microgravity that might be exploited to enhance protein crystal growth. The major factor is the elimination of density driven convective flow. Other factors that can be controlled in the absence of gravity is the sedimentation of growing crystals in a gravitational field, and the potential advantage of doing containerless crystal growth. As a result of these theories and facts, one can readily understand why the microgravity environment of an Earth orbiting vehicle seems to offer unique opportunities for the protein crystallographer. This perception has led to the establishment of the Protein Crystal Growth in a Microgravity Environment (PCG/ME) project. The results of experiments already performed during STS missions have in many cases resulted in large protein crystals which are structurally correct. Thus, the near term objective of the PCG/ME project is to continue to improve the techniques, procedures, and hardware systems used to grow protein crystals in Earth orbit.

Bugg, Charles E.↗

NASA NTRS1996

A Proof of Concept Experiment for Reducing Skin Friction by Using a Micro-Blowing Technique

A proof of concept experiment for reducing skin friction has been conducted in the Advanced Nozzle and Engine Components Test Facility at the NASA Lewis Research Center. In this unique concept, called the micro-blowing technique (MBT), an extremely small amount of air was blown vertically through very small holes to reduce the surface roughness and to control the gradient of the flow velocity profile on the surface thereby reducing skin friction. Research revealed that the skin was the most important factor to make this concept achievable. The proposed skin consisted of two layers. The inner layer was a low permeable porous skin for distributing the blowing air evenly while the outer layer with small holes controlled the vertical or nearly vertical blowing air. Preliminary experimental results showed that the MBT has the potential of a very large reduction in skin friction below the skin friction of a nonporous plain flat plate. Of the skins tested, three have been identified as the MBT skins. They provided very low unblown skin friction such that a large skin friction reduction, below a flat plate value, was achieved with very small amounts of blowing air. The reduction in skin friction of 55 percent was achieved at the Mach number of 0.3 for the exhaust pressure of 0.85 atm, and 60 percent reduction was obtained for the exhaust pressure of 0.24 atm (corresponding to 10 700-m altitude) at the same Mach number. A significant reduction in skin friction of over 25 percent was achieved for the exhaust pressure of 0.24 atm at the Mach number of 0.7. This implied that the MBT could be applied to a wide range of flight conditions. It is also believed that additional 10 percent reduction could be obtained by eliminating the gap between the inner layer and the outer layer. The aspect ratio of the vertical small holes for the outer layer of the MBT skin should be larger than 4 based on the preliminary conclusion from this test. Many experiments are needed to find out the optimal MBT skin. The penalty associated with the MBT needs to be assessed. However, preliminary results indicated that the MBT could provide a 25 to 35 percent reduction for real-world application. The concept can be applied to not only an airplane, but also a missile, a submarine (micro-blow water instead of air), and an ocean liner.

Hwang, Danny P.↗

NASA NTRS2014

Surge Pressure Mitigation in the Global Precipitation Measurement Mission Core Propulsion System

The Global Precipitation Measurement (GPM) mission is an international partnership between NASA and JAXA whose Core spacecraft performs cutting-edge measurements of rainfall and snowfall worldwide and unifies data gathered by a network of precipitation measurement satellites. The Core spacecraft's propulsion system is a blowdown monopropellant system with an initial hydrazine load of 545 kg in a single composite overwrapped propellant tank. At launch, the propulsion system contained propellant in the tank and manifold tubes upstream of the latch valves, with low-pressure helium gas in the manifold tubes downstream of the latch valves. The system had a relatively high beginning-of- life pressure and long downstream manifold lines; these factors created conditions that were conducive to high surge pressures. This paper discusses the GPM project's approach to surge mitigation in the propulsion system design. The paper describes the surge testing program and results, with discussions of specific difficulties encountered. Based on the results of surge testing and pressure drop analyses, a unique configuration of cavitating venturis was chosen to mitigate surge while minimizing pressure losses during thruster maneuvers. This paper concludes with a discussion of overall lessons learned with surge pressure testing for NASA Goddard spacecraft programs.

Pressure↗

NASA NTRS2019

Heatshield Erosion Due to Dust Particle Impacts on the Schiaparelli Capsule During Martian Entry

One of the unique features of spacecraft entering the atmosphere of Mars is the possibility of a major dust storm occurring during the entry. Design of the thermal protection system (TPS) for Mars missions have to account for the possibility of dust erosion when estimating the thickness of the TPS. Because weight is always a critical factor in designing entry vehicles, accurate assessment of dust erosion is necessary to avoid over-design of the TPS.This study will present computational results of heatshield erosion due to dust particle impacts on the ExoMars Schiaparelli capsule if it had encountered a dust storm during its October 2016 entry. A one-way coupling approach is used where particle trajectories are computed based on an underlying CFD flow solution. Based on a distribution of particle sizes ranging from 1 to 18 microns in diameter, the Icarus material response solver predicted approximately 1 mm of TPS heatshield erosion due to particle impacts, which was 40% of the value due to material charring.

thermal protection system↗

NASA NTRSDate not supplied

Simulating Micrometeoroid Bombardment on Mercury: Identifying New Space Weathering Features in the Laboratory

Airless bodies are continually exposed to the harsh interplanetary space environment, causing the alteration of their surfaces through a process known as space weathering (SW). SW is dominated by solar wind irradiation and micrometeoroid bombardment, which together alter the spectral, microstructural, and chemical characteristics of grains on the surface of airless bodies. The effects of SW are variable and depend on the heliocentric distance and the initial composition of the planetary surface, among other factors. On the Moon and S- type asteroids, it is well established that SW darkens and reddens the surface of these bodies and attenuates absorption bands across the Vis-NIR wavelengths. These spectral effects are largely the result of the production of metallic Fe nanoparticles (npFe). However, Mercury’s SW environment is unique compared to the Moon and S-type asteroids. Mercury is a geochemical endmember, with a surface composition low in Fe (<2 wt.%) and enriched in volatile components, including regions of the surface hypothesized to contain up to 4 wt.% graphite in the low reflectance material (LRM). In fact, the presence of graphite on Mercury has been hypothesized to act as a reducing agent for silicates during SW to produce Si-bearing Fe-rich metal. In addition, its location in the solar system exposes Mercury to an extreme SW environment, with the surface of the planet experiencing an intense solar wind flux and higher flux and velocity of micrometeoroid impactors compared to the Moon and S-type asteroids. The effects that such harsh SW has on materials with the unique compositional characteristics of Mercury are not well constrained. To better understand SW at Mercury, we must investigate these processes in the laboratory. Here, we present the results of our analyses of the spectral, microstructural and chemical characteristics of Mercury analog samples irradiated by pulsed laser to simulate the short duration, high temperature events associated with micrometeoroid impacts.

Nick Bott↗

NASA NTRSDate not supplied

BioSentinel: Forging the path for Deep Space CubeSat Missions

The BioSentinel mission was launched in 2022 aboard the SLS launch vehicle as part of the Artemis-I campaign and continues mission operations into 2024. The 6U CubeSat has been characterizing deep space radiation at large distances from Earth. This presentation gives a status of the mission performance to date, as well as some of the lessons learned from project. BioSentinel has achieved unprecedented performance as an SLS secondary payload due to preparation, planning, and a robust design. Pre-launch antenna and interface testing with both DSN and ESA confirmed command and data pathways and allowed for operational flexibility in the critical early hours post-deployment. Mission Operations simulations prior to launch identified potential risks and trained operators to respond in flight, preparing the team to react quickly and successfully to detumble the spacecraft and enter a power-positive state. The spacecraft would not have survived without the inclusion of the trailblazing 3D-printed composite cold gas propulsion system. The non-standard tank geometry enabled efficient use of the limited space available in the CubeSat form factor as well as the capability to detumble the spacecraft and manage momentum for extended mission durations, while providing sufficient margin to execute potential delta-V maneuvers. Following the conclusion of the primary science mission, the Linear Energy Transfer (LET) Spectrometer has continued to collect solar and galactic radiation data from its unique location in heliocentric orbit. The free space dataset offered by the BioSentinel LET is a valuable source of data for both model validation and future mission planning. As the spacecraft travels farther from Earth it is poised to provide longitudinally distributed measurements of solar particle events during solar maximum. NASA Ames led development of the BioSentinel spacecraft to operate for long durations in deep space. The novel subsystems and COTS components that comprise the BioSentinel bus can serve as a template for future deep space missions, while the lessons the team has learned from well over a year of continuous operations will enable improved performance in the generation of deep space CubeSat missions.

BioSentinel↗

NASA NTRS2024

Big Bend Ecological Forecasting: Integrating Earth Observations Into Invasive Species Management Decisions in Big Bend National Park in Texas

Located in Brewster County Texas, U.S., along the Texas-Mexico border, Big Bend National Park is 3,243 square kilometers of desert, mountains, and rivers. NASA’s MSFC Spring 2024 DEVELOP Team partnered with the National Park Service (NPS), to address the environmental concern of perineal invasive grasses in Big Bend National Park. Buffelgrass (Cenchrus ciliaris), introduced to the park in the 1940’s, poses an ongoing threat, and causes habitat destruction for many of the park’s native ecosystems. Buffelgrass amplifies fire risk in the park, aids in the destruction of historic structures, and alters stream channels. To address the rising concern of Buffelgrass presence, unique advanced spatial technique applications were necessary to construct a habitat suitability model and perform a comprehensive fire risk assessment. A habitat suitability model was developed considering climate, vegetation, and phenological variables, in addition to physical and topographical variables. Subsequently, a fire risk model was developed, taking into account fire history data, accessibility factors, climate trends and predictions, along with developed areas. Multi-Source Land Surface Phenology (LSP) Sentinel-2 and Landsat 8 Operational Land Imager (OLI) imagery were used to predict Buffelgrass hotspot locations throughout the park. These analyses allowed the identification of optimal Buffelgrass habitat and hotspot locations, as well as park zones that reflect the greatest risk for future Buffelgrass invasion and fire risk. The collective results of the habitat suitability model, fire risk assessment, and Buffelgrass hot spot identification will allow the NPS to facilitate efficient mitigation measures and management strategies, and improved resource allocation where it’s most needed.

remote sensing↗

DOE OSTI2024

Understanding the Origin of Negative Temperature Dependence and Activity of N-Coordinated Cobalt Sites During Ethylene Dimerization

The on-demand production of short-chain linear alpha olefins (LAOs; C4-C8) via C2H4 dimerization and oligomerization is industrially attractive, prompting extensive research on designing active, selective, and stable catalysts for industrial use. Cobalt supported on ammoniated carbon (Co(NH3)x/C) catalysts have shown remarkable activity and selectivity in this process. However, critical aspects such as the active phase, active site structure, the role of the catalyst support, cobalt loading effects, and the inverse correlation of the reaction rate with temperature remain inadequately understood. This study systematically explores these factors using a combination of steady-state differential catalytic tests, in situ molecular characterization including diffuse reflectance UV-Vis (DR-UV-Vis), Infrared, and Raman spectroscopies, and ex situ X-ray diffraction (XRD) and high annular aberration-corrected dark field transmission electron microscopy (HAADF-STEM). Various supports (SiO2, Al2O3, NH4-ZSM-5, g-C3N4, and C) and cobalt loadings (1.0-3.0 Co nm-2) were studied to determine the optimal catalyst composition and identify the active phase and sites. Carbon-supported catalysts uniquely produce C4-8 LAOs during C2H4 dimerization, with site-time-yield remaining constant (~10-3 s-1) for 1.0-4.0 Co nm-2 at prolonged reaction times (24-48?h time-on-stream). At higher loadings of 6.0 Co nm-2, the formation of crystalline CoO and Co3O4 phases reduces catalytic activity and LAO selectivity. Our findings show that active catalysts lack crystalline cobalt oxides and instead feature dispersed Co2+ sites, tetra-coordinated to a mix of N/NH3 and O/H2O ligands, which catalyze C2H4 dimerization via the Cossee-Arlman mechanism, exhibiting 1st order dependence on C2H4 concentration. The observed inverse rate-temperature correlation is attributed to compensation effects (i.e., presence of Cremer-Constable relationship) linked to changes in adsorption enthalpic and entropic factors.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

DOE OSTI2022

BASS. XXIX. The Near-infrared View of the Broad-line Region (BLR): The Effects of Obscuration in BLR Characterization

Virial black hole (BH) mass (M BH ) determination directly involves knowing the broad-line region (BLR) clouds' velocity distribution, their distance from the central supermassive BH (R BLR ), and the virial factor (f). Understanding whether biases arise in M BH estimation with increasing obscuration is possible only by studying a large (N > 100) statistical sample of obscuration-unbiased (hard) X-ray-selected active galactic nuclei (AGNs) in the rest-frame near-infrared (0.8–2.5 μm) since it penetrates deeper into the BLR than the optical. We present a detailed analysis of 65 local Burst Alert Telescope (BAT) selected Seyfert galaxies observed with Magellan/FIRE. Adding these to the near-infrared BAT AGN spectroscopic survey database, we study a total of 314 unique near-infrared spectra. While the FWHMs of Hα and near-infrared broad lines (He i, Paβ, Paα) remain unbiased to either BLR extinction or X-ray obscuration, the Hα broad-line luminosity is suppressed when N H ≳ 10 21 cm –2 , systematically underestimating M BH by 0.23–0.46 dex. Near-infrared line luminosities should be preferred to Hα until N H < 10 22 cm –2 , while at higher obscuration a less-biased R BLR proxy should be adopted. We estimate f for Seyfert 1 and 2 using two obscuration-unbiased M BH measurements, i.e., the stellar velocity dispersion and a BH mass prescription based on near-infrared and X-ray, and find that the virial factors do not depend on the redshift or obscuration, but some broad lines show a mild anticorrelation with M BH . Furthermore, our results show the critical impact obscuration can have on BLR characterization and the importance of the near-infrared and X-rays for a less-biased view of the BLR.

79 ASTRONOMY AND ASTROPHYSICS↗

DOE OSTI2022

Thermoelectric Performance of the 2D Bi 2 Si 2 Te 6 Semiconductor

Bi 2 Si 2 Te 6 , a 2D compound, is a direct band gap semiconductor with an optical band gap of 0.25 eV, and is a promising thermoelectric material. Single-phase Bi 2 Si 2 Te 6 is prepared by a scalable ball-milling and annealing process and the highly densified polycrystalline samples are prepared by spark plasma sintering. Bi 2 Si 2 Te 6 shows a p-type semiconductor transport behavior and exhibits an intrinsically low lattice thermal conductivity of ~0.48 Wm -1 K -1 (cross-plane) at 573 K. The first-principles density functional theory calculations indicate that such low lattice thermal conductivity is derived from the interactions between acoustic phonons and low-lying optical phonons, local vibrations of Bi, the low Debye temperature and strong anharmonicity result from the unique 2D crystal structure and metavalent bonding of Bi 2 Si 2 Te 6 . The Bi 2 Si 2 Te 6 exhibits an optimal figure of merit ZT of ~0.51 at 623 K, which can be further enhanced by the substitution of Bi with Pb. Pb doping leads to a large increase in power factor S 2 σ, from ~4.0 μWcm -1 K- 2 of Bi 2 Si 2 Te 6 to ~8.0 μWcm -1 K -2 of Bi 1.98 Pb 0.02 Si 2 Te 6 at 775 K, owing to the increase in carrier concentration. Moreover, Pb doping induces a further reduction in the lattice thermal conductivity to ~0.38 Wm -1 K -1 (cross-plane) at 623 K in Bi 1.98 Pb 0.02 Si 2 Te 6 ,. The simultaneous optimization of the power factor and lattice thermal conductivity achieves a peak ZT of ~0.90 at 723 K and a high average ZT of ~0.66 at 400–773 K in Bi 1.98 Pb 0.02 Si 2 Te 6 .

36 MATERIALS SCIENCE↗

DOE OSTI2021

Landau Damping with Electron Lenses in Space-Charge Dominated Beams

Further progress of fundamental physics requires accelerated beams of high intensity. The intensities, however, are limited by many factors, including coherent beam instabilities. Usual methods to control the instabilities, such as octupole magnets, beam feedback dampers and employment of chromatic effects, may be ineffective or insufficient. In this study, electron lenses were proposed as a means to provide stabilizing spread in the beam betatron frequencies. It was shown that electron lenses are uniquely effective for Landau damping of transverse beam instabilities in high energy particle accelerators, and that their employment does not compromise incoherent (single particle) stability, dynamic aperture and the beam lifetime. Here we consider effectiveness of the Landau damping with electron lenses when the space charge tune shift cannot be neglected. We demonstrate that the desired stability can be assured with proper choice of the electron beam parameters and current distributions.

43 PARTICLE ACCELERATORS↗

NASA NTRS1989

Crew system dynamics - Combining humans and automation

Some of the human factor issues involved in effectively combining human and automated systems are examined with particular reference to spaceflights. The concepts of the crew system and crew systems dynamics are defined, and the present status of crew systems is summarized. The possibilities and potential problems aasociated with the use of automated systems are discussed, as are unique capabilities and possible errors introduced by human participants. It is emphasized that the true integration of human and automated systems must allow for the characteristics of both.

Connors, Mary↗