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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 883 records · Page 49

Mathematical and statistical analysis of the effect of boron on yield parameters of wheat

The main objective of this research is to investigate the effect of foliar applications of boron at different growth stages on yield and yield parameters of wheat. The contribution of boron in achieving yield parameters is described by second degree polynomial equations, with high statistical confidence (p<0.01; F theoretical < F calculated, according to ANOVA test, for Alfa = 0.05). Regression analysis, based on R{sup 2} values obtained, made it possible to evaluate the particular contribution of boron to the realization of yield parameters. This was lower for spike length (R{sup 2} = 0.812), thousand seeds weight (R{sup 2} = 0.850) and higher in the case of the number of spikelets (R{sup 2} = 0.936) and the number of seeds on a spike (R{sup 2} = 0.960). These results confirm that boron plays an important part in achieving the number of seeds on a spike in the case of wheat, as the contribution of this element to the process of flower fertilization is well-known. In regards to productivity elements, the contribution of macroelements to yield quantity is clear, the contribution of B alone being R{sup 2} = 0.868.

60 APPLIED LIFE SCIENCES↗

Mathematical modelling and linear stability analysis of laser fusion cutting

A model for laser fusion cutting is presented and investigated by linear stability analysis in order to study the tendency for dynamic behavior and subsequent ripple formation. The result is a so called stability function that describes the correlation of the setting values of the process and the process’ amount of dynamic behavior.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

Mathematical simulation of an experimental prototype of a high-speed nonreturn-to-zero differential phase-shift-keying fibre-optic communication system

The influence of chromatic dispersion, optical power, and nonlinear distortions in a fibre-optic communication system on the quality of data transmission based on nonreturn-to-zero differential phase-shift keying at a rate of 40 Gbit s{sup -1} in one spectral channel have been numerically simulated and experimental studied. The results of direct numerical calculations and estimates based on the quality factor (Q factor) are in qualitative agreement with the experimental data. It is found experimentally that the dependence of the error rate on the accumulated dispersion has a plateau in the range from -50 to 50 ps nm{sup -1}; a similar dependence is obtained in the numerical calculation based on the Q factor. The optimal calculated value of the power launched into each of 10 sections of a line with a total length of 1000 km is 2 - 4 dBm; it corresponds to the experimental value of 3 dBm.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

On mathematical and physical approaches to constructing a quantum cluster state in continuous variables, or is it possible to construct a cluster from different modes?

We consider the problems of constructing a cluster state from a set of orthogonal modes. It is shown that the commonly used unitary transformation is not reduced in this case to a set of standard operations of linear optics performed over fields in a squeezed state, but should be supplemented by a more complicated operation of a noise-free transformation of the quantum signal profile. At the same time, if it is possible to form a cluster whose node amplitudes have different time profiles, this property does not interfere with the performance of calculations on the cluster. (paper)

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

A mathematical model of asynchronous data flow in parallel computers *

Abstract We present a simplified model of data flow on processors in a high-performance computing framework involving computations necessitating inter-processor communications. From this ordinary differential model, we take its asymptotic limit, resulting in a model which treats the computer as a continuum of processors and data flow as an Eulerian fluid governed by a conservation law. We derive a Hamilton–Jacobi equation associated with this conservation law for which the existence and uniqueness of solutions can be proven. We then present the results of numerical experiments for both discrete and continuum models; these show a qualitative agreement between the two and the effect of variations in the computing environment’s processing capabilities on the progress of the modelled computation.

Barnard, Richard C.↗

Solutions to Peto's paradox revealed by mathematical modelling and cross-species cancer gene analysis

Whales have 1000-fold more cells than humans and mice have 1000-fold fewer; however, cancer risk across species does not increase with the number of somatic cells and the lifespan of the organism. This observation is known as Peto's paradox. How much would evolution have to change the parameters of somatic evolution in order to equalize the cancer risk between species that differ by orders of magnitude in size? Analysis of previously published models of colorectal cancer suggests that a two- to three-fold decrease in the mutation rate or stem cell division rate is enough to reduce a whale's cancer risk to that of a human. Similarly, the addition of one to two required tumour-suppressor gene mutations would also be sufficient. Also, we surveyed mammalian genomes and did not find a positive correlation of tumour-suppressor genes with increasing body mass and longevity. However, we found evidence of the amplification of TP53 in elephants, MAL in horses and FBXO31 in microbats, which might explain Peto's paradox in those species. Lastly, exploring parameters that evolution may have fine-tuned in large, long-lived organisms will help guide future experiments to reveal the underlying biology responsible for Peto's paradox and guide cancer prevention in humans.

59 BASIC BIOLOGICAL SCIENCES↗

Setting the threshold for high throughput detectors: A mathematical approach for ensembles of dynamic, heterogeneous, probabilistic anomaly detectors

Cyber operations now manage a high volume of heterogeneous log data. Anomaly Detection (AD) in such operations involves multiple (e.g., per IP, per data type) ensembles of detectors modeling heterogeneous characteristics (e.g., rate, size, type) often with adaptive online models producing alerts in near real time. Because of the high data volume, setting the threshold for each detector in such a system is an essential yet underdeveloped configuration issue that, if slightly mistuned, can leave the system useless, either producing a myriad of alerts (and flooding downstream systems) or giving none. In this work, we build on the foundations of Ferragut et al. to provide a set of rigorous results for understanding the relationship between threshold values and alert quantities for probabilistic detectors. This informs an algorithm for setting the threshold of multiple, heterogeneous, possibly dynamic detectors completely a priori, in principle. Indeed, if the underlying distribution of the incoming data is known, the algorithm provides provably manageable thresholds. If the distribution is unknown (poorly estimated), our analysis gives insight into how the model distribution differs from the actual distribution, indicating refitting is necessary. We provide empirical experiments, regulating the alert rate of a system with ≈2,500 adaptive detectors scoring over 1.5M events in 5 hours of timestamps. Further, we demonstrate on real network data and detection framework of Harshaw et al. the alternative case, demonstrating that the inability to regulate alerts indicates how the detection model is not a good fit to the data.

Bridges, Robert↗

Mathematics of Gas Ingress of Hermetic Packages

Herein, we have derived a gas ingress and egress equation from the first principles of ideal gases. This work is intended to benefit the hermetic microelectronics packaging community, but it may be applied to other fields that require a deep understanding of gas ingress and egress dynamics. The equation outlined herein encompasses package material properties, package characteristics, hermetic testing conditions, and service conditions. It serves as a practical utility for calculating package pressure changes due to gas ingress and egress and, therefore, a power tool for component and system service life predictions.

42 ENGINEERING↗

WE-E-17A-07: Patient-Specific Mathematical Neuro-Oncology: Biologically-Informed Radiation Therapy and Imaging Physics

Purpose: To demonstrate a method of generating patient-specific, biologically-guided radiation therapy (RT) plans and to quantify and predict response to RT in glioblastoma. We investigate the biological correlates and imaging physics driving T2-MRI based response to radiation therapy using an MRI simulator. Methods: We have integrated a patient-specific biomathematical model of glioblastoma proliferation, invasion and radiotherapy with a multiobjective evolutionary algorithm for intensity-modulated RT optimization to construct individualized, biologically-guided plans. Patient-individualized simulations of the standard-of-care and optimized plans are compared in terms of several biological metrics quantified on MRI. An extension of the PI model is used to investigate the role of angiogenesis and its correlates in glioma response to therapy with the Proliferation-Invasion-Hypoxia- Necrosis-Angiogenesis model (PIHNA). The PIHNA model is used with a brain tissue phantom to predict tumor-induced vasogenic edema, tumor and tissue density that is used in a multi-compartmental MRI signal equation for generation of simulated T2- weighted MRIs. Results: Applying a novel metric of treatment response (Days Gained) to the patient-individualized simulation results predicted that the optimized RT plans would have a significant impact on delaying tumor progression, with Days Gained increases from 21% to 105%. For the T2- MRI simulations, initial validation tests compared average simulated T2 values for white matter, tumor, and peripheral edema to values cited in the literature. Simulated results closely match the characteristic T2 value for each tissue. Conclusion: Patient-individualized simulations using the combination of a biomathematical model with an optimization algorithm for RT generated biologically-guided doses that decreased normal tissue dose and increased therapeutic ratio with the potential to improve survival outcomes for treatment of glioblastoma. Simulated T2-MRI is shown to be consistent with known physics of MRI and can be used to further investigate biological drivers of imaging-based response to RT.

60 APPLIED LIFE SCIENCES↗

Mathematical simulation of heat and mass transfer in a cylindrical channel versus the tangential momentum accommodation coefficient

The process of heat and mass transfer in a long cylindrical channel has been considered in terms of the mirror–diffuse model of the Maxwell boundary condition. The Hazen–Williams equation is used as a basic equation of the process kinetics. A constant temperature gradient is maintained in the channel. The heat and mass fluxes through the cross section of the channel versus the tangential momentum accommodation coefficient have been calculated in a wide range of the Knudsen number. The heat flux profiles have been constructed. A comparison with relevant published data has been carried out.

42 ENGINEERING↗

Understanding Impacts of Catalyst-Layer Thickness on Fuel-Cell Performance via Mathematical Modeling

In this article, a two-dimensional, multiphase, transient model is introduced and used to explore the impact of catalyst-layer thickness on performance. In particular, the tradeoffs between water production and removal through transport or evaporation are highlighted, with a focus on low-temperature performance. For the latter, a case study of an ultra-thin catalyst layer is undergone to explore how various material properties alter the steady-state and startup performance of a cell. The findings provide understanding and guidance to optimize fuel-cell performance with thin electrodes.

25 ENERGY STORAGE↗