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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 91 records · Page 5

Planned Detection and Amplification of Infared Synchrotron Radiation for Electron-Beam Diagnostics and Manipulations

Amplification of beam-induced radiation (e.g. synchrotron or undulator radiation) is a necessary component of optical stochastic cooling of hadrons or heavy ions. We discuss a proposal to measure and amplify synchrotron radiation from a bending magnet of the Advanced Photon Source. The measurements will be in the short-wavelength infrared region (SWIR) and amplification will be accomplished using a pumped Chromium:Zinc Selenide (Cr:ZnSe) crystal with maximum gain at λ≅ 2.2~μm.

43 PARTICLE ACCELERATORS↗

Towards Quantum-Limited Cryogenic Amplification for Multi-Qubit Platforms

Here we present the development of the building blocks of a Josephson parametric amplifier (JPA), namely the superconducting quantum interference device (SQUID) and the inductive pick-up coil that permits current coupling from a quantum dot into the SQUID. We also discuss our efforts in making depletion mode quantum dots using delta doped GaAs quantum wells. Because quantum dot based spin qubits utilize very low-level (~10 - 100pA), short duration (1ms - 1μs) current signals for state preparation and readout, these systems require close proximity cryogenic amplification to prevent signal corruption. Common amplification methods in these semiconductor quantum dots rely on heterojunction bipolar transistors (HBTs) and high electron mobility transistors (HEMTs) to amplify the readout signal from a single qubit. The state of the art for HBTs and HEMTs produce approximately 10µW of power when operating at high bandwidths. For few-qubit systems this level of heat dissipation is acceptable. However, for scaling up the number of qubits to several hundred or a thousand, the heat load produced in a 1 to 1 amplifier to qubit arrangement would overload the cooling capacity of a common dilution refrigerator, which typically has a cooling power of ~100µW at its base temperature. Josephson parametric amplifiers have been shown to dissipate ~1pW of power with current sensitivies on par with HBTs and HEMTs and with bandwidths 30 times that of HBTs and HEMTs, making them attractive for multi-qubit platforms. In this report we describe in detail the fabrication process flow for developing inductive pick-up coils and the fabrication and measurement of NbTiN and A1/A1Ox/A1 SQUIDs.

75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND↗

Modeling of Charge Amplification in LArTPCs

Single-phase liquid argon time projection chambers (LArTPCs) are an important part of Fermilab's neutrino experimental program. Current LArTPCs are able to detect interactions producing energy deposits above the MeV scale, and focus on neutrinos at GeV energies. The Liquid Argon Charge Amplification Device, or LArCADe, program aims to employ modified anode geometries in order to obtain electron avalanches that would help reduce detection thresholds, opening the door to new physics opportunities at the keV scale (e.g. CEvNS and dark-matter WIMP searches). To model and quantify this phenomenon, a simulation of electron transport in LAr was built, able to simulate excitations and ionizations in non-uniform fields. Using COMSOL simulations of the anode structures, the built simulation produced quantitative and realistic estimates of LAr charge amplification near different tip geometries. These results will inform the next generation of tips produced for LArCADe.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

LArCADe | Liquid Argon Charge Amplification Devices

The Liquid Argon Charge Amplification Devices (LArCADe) project is an R$\&$D effort aimed at developing instrumentation capable of lowering detection thresholds for ionization signatures in liquid and gaseous argon detectors and achieving O(100 $\mu$m) position resolution. The core concept is the use of sharp “tip arrays” that generate strong local electric-field enhancement, enabling charge amplification and collection with improved spatial resolution. A key physics motivation for this work is to enhance the experimental sensitivity of Coherent Elastic Neutrino-Nucleus Scattering (CEvNS) measurements to low-energy nuclear recoils by enabling spatially resolved charge reconstruction at reduced ionization thresholds, with the goal of achieving event-by-event energy reconstruction for interactions originating from localized accelerator or astrophysical neutrino sources. This poster will present the current status of the instrumentation R$\&$D, which leverages Fermilab’s Noble Liquid Test Facility and UC Santa Barbara’s Nanofabrication Facility, and will discuss the potential physics impact of this technology.

Antonakis, Alexander [UC, Santa Barbara]↗

Rapid detection of mexX in Pseudomonas aeruginosa based on CRISPR-Cas13a coupled with recombinase polymerase amplification

The principal pathogen responsible for chronic urinary tract infections, immunocompromised hosts, and cystic fibrosis patients is Pseudomonas aeruginosa , which is difficult to eradicate. Due to the extensive use of antibiotics, multidrug-resistant P. aeruginosa has evolved, complicating clinical therapy. Therefore, a rapid and efficient approach for detecting P. aeruginosa strains and their resistance genes is necessary for early clinical diagnosis and appropriate treatment. This study combines recombinase polymerase amplification (RPA) and clustered regularly interspaced short palindromic repeats-association protein 13a (CRISPR-Cas13a) to establish a one-tube and two-step reaction systems for detecting the mexX gene in P. aeruginosa . The test times for one-tube and two-step RPA-Cas13a methods were 5 and 40 min (including a 30 min RPA amplification reaction), respectively. Both methods outperform Quantitative Real-time Polymerase Chain Reactions (qRT-PCR) and traditional PCR. The limit of detection (LoD) of P. aeruginosa genome in one-tube and two-step RPA-Cas13a is 10 aM and 1 aM, respectively. Meanwhile, the designed primers have a high specificity for P. aeruginosa mexX gene. These two methods were also verified with actual samples isolated from industrial settings and demonstrated great accuracy. Furthermore, the results of the two-step RPA-Cas13a assay could also be visualized using a commercial lateral flow dipstick with a LoD of 10 fM, which is a useful adjunt to the gold-standard qRT-PCR assay in field detection. Taken together, the procedure developed in this study using RPA and CRISPR-Cas13a provides a simple and fast way for detecting resistance genes.

Zhu, Xiao-Xuan↗

Constraining Magnetic Field Amplification in SN Shocks Using Radio Observations of SNe 2011fe and 2014J

We modeled the radio non-detection of two Type Ia supernovae (SNe), SN 2011fe and SN 2014J, considering synchrotron emission from the interaction between SN ejecta and the circumstellar medium. For ejecta whose outer parts have a power-law density structure, we compare synchrotron emission with radio observations. Assuming that 20% of the bulk shock energy is being shared equally between electrons and magnetic fields, we found a very low-density medium around both the SNe. A less tenuous medium with particle density ∼1 cm{sup −3}, which could be expected around both SNe, can be estimated when the magnetic field amplification is less than that presumed for energy equipartition. This conclusion also holds if the progenitor of SN 2014J was a rigidly rotating white dwarf (WD) with a main-sequence (MS) or red giant companion. For a He star companion, or a MS for SN 2014J, with 10% and 1% of bulk kinetic energy in magnetic fields, we obtain mass-loss rates of <10{sup −9} and <∼4×10{sup −9} M{sub ⊙} yr{sup −1} for a wind velocity of 100 km s{sup −1}. The former requires a mass accretion efficiency of >99% onto the WD, but is less restricted for the latter case. However, if the tenuous medium is due to a recurrent nova, it is difficult from our model to predict synchrotron luminosities. Although the formation channels of SNe 2011fe and 2014J are not clear, the null detection in radio wavelengths could point toward a low amplification efficiency for magnetic fields in SN shocks.

79 ASTRONOMY AND ASTROPHYSICS↗

Magnetic Field Amplification by a Plasma Cavitation Instability in Relativistic Shock Precursors

Abstract Plasma streaming instabilities play an important role in magnetic field amplification and particle acceleration in relativistic shocks and their environments. However, in the far shock precursor region where accelerated particles constitute a highly relativistic and dilute beam, streaming instabilities typically become inefficient and operate at very small scales when compared to the gyroradii of the beam particles. We report on a plasma cavitation instability that is driven by dilute relativistic beams and can increase both the magnetic field strength and coherence scale by orders of magnitude to reach near-equipartition values with the beam energy density. This instability grows after the development of the Weibel instability and is associated with the asymmetric response of background leptons and ions to the beam current. The resulting net inductive electric field drives a strong energy asymmetry between positively and negatively charged beam species. Large-scale particle-in-cell simulations are used to verify analytical predictions for the growth and saturation level of the instability and indicate that it is robust over a wide range of conditions, including those associated with pair-loaded plasmas. These results can have important implications for the magnetization and structure of shocks in gamma-ray bursts, and more generally for magnetic field amplification and asymmetric scattering of relativistic charged particles in plasma astrophysical environments.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Current Status of Chirped-Pulse Amplification Technology and Its Applications

We survey current status of chirped-pulse amplification development and its applications. We start with the review of optical compressor and stretcher as well as the amplification techniques. The methods to control spatial and temporal profile of the laser pulse as well as the state-of-the-arts spatiotemporal control techniques and designs of high repetition-rate amplifiers are discussed. Examples of applications in medical and particle acceleration are introduced.

43 PARTICLE ACCELERATORS↗

Micro-fluidic partitioning between polymeric sheets for chemical amplification and processing

A system for fluid partitioning for chemical amplification or other chemical processing or separations of a sample, comprising a first dispenser of a first polymeric sheet, wherein the first polymeric sheet contains chambers; a second dispenser of a second polymeric sheet wherein the first dispenser and the second dispenser are positioned so that the first polymeric sheet and the second polymeric sheet become parallel; a dispenser of the fluid positioned to dispense the fluid between the first polymeric sheet and the second polymeric sheet; and a seal unit that seals the first polymeric sheet and the second polymeric sheet together thereby sealing the sample between the first polymeric sheet and the second polymeric sheet and partitioning the fluid for chemical amplification or other chemical processing or separations.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Method for chemical amplification based on fluid partitioning in an immiscible liquid

A system for nucleic acid amplification of a sample comprises partitioning the sample into partitioned sections and performing PCR on the partitioned sections of the sample. Another embodiment of the invention provides a system for nucleic acid amplification and detection of a sample comprising partitioning the sample into partitioned sections, performing PCR on the partitioned sections of the sample, and detecting and analyzing the partitioned sections of the sample.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Chemical amplification based on fluid partitioning

A system for nucleic acid amplification of a sample comprises partitioning the sample into partitioned sections and performing PCR on the partitioned sections of the sample. Another embodiment of the invention provides a system for nucleic acid amplification and detection of a sample comprising partitioning the sample into partitioned sections, performing PCR on the partitioned sections of the sample, and detecting and analyzing the partitioned sections of the sample.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Chemical amplification based on fluid partitioning

A system for nucleic acid amplification of a sample comprises partitioning the sample into partitioned sections and performing PCR on the partitioned sections of the sample. Another embodiment of the invention provides a system for nucleic acid amplification and detection of a sample comprising partitioning the sample into partitioned sections, performing PCR on the partitioned sections of the sample, and detecting and analyzing the partitioned sections of the sample.

Anderson, Brian L.↗

Privacy Amplification for Episodic Training Methods

It has been shown that differential privacy bounds improve when subsampling within a randomized mechanism. Episodic training, utilized in many standard machine learning techniques, uses a multistage subsampling procedure which has not been previously analyzed for privacy bound amplification. In this paper, we focus on improving the calculation of privacy bounds in episodic training by thoroughly analyzing privacy amplification due to subsampling with a multi-stage subsampling procedure. The newly developed bound can be incorporated into existing privacy accounting methods.

Tombs, Vandy↗

Ultra-Long Distance BOTDA Sensor System Employing Hybrid Amplification and Advanced Noise Reduction Techniques

Brillouin Optical Time Domain Analysis (BOTDA) sensor systems play a pivotal role in distributed sensing, which enables precise measurements of strain and temperature across extensive fiber lengths. This research offers a comprehensive strategy to extend the sensing range of BOTDA systems beyond tens of kilometers while maintaining high spatial resolutions. Such enhanced sensing is realized through the integration of distributed Raman amplification, inline amplification using erbium-doped fiber amplifiers (EDFA), and advanced noise reduction techniques. Optimizing Raman pump and probe wave profiles ensures the robustness of Brillouin scattering signals, effectively countering attenuation-induced losses. Additionally, enhancing weak Brillouin signals by strategically placing EDFAs at optimal fiber locations keeps sensor sensitivity high. Leveraging inherent redundancy in measured data as a function of frequency and fiber distance, the non-local means (NLM) filter removes noise while preserving essential physical information. In summary, this research has shown a holistic exploration of extending BOTDA’s distance sensing capabilities up to 150 km with spatial resolutions of 8 meters.

Bhatta, Hari↗

Methods for isothermal molecular amplification with nanoparticle-based reactions

The present method of detection involves increasing an amount of analyte molecules by an isothermal molecular amplification approach. In the present approach a starting molecule of interest may be amplified through a reaction it induces with specifically engineered and functionalized particles, namely protected particles A and storage particles B. This reaction may result in a set of output DNA molecules that is larger in number than the input DNA molecules. Thus the reaction between nanoparticles for amplification of a certain DNA sequence (input DNA molecules) may occur when there is a match with a targeted molecule (stored molecules on storage particles B) and if the DNA sequence of the input DNA molecules does not match (partially or completely) the targeted molecule the reaction may not occur. Without a certain molecular input of the input DNA molecule the reaction may not occur.

Gang, Oleg↗

Linear Light Amplifier and Amplification of N-Photon States

We consider a linear quantum amplifier consisting of NA two-level atoms and study the problem of amplification of N-photon states. The N-photon states are associated with N-quantum states of the harmonic oscillator. We show that the process of interaction of the electromagnetic field with atoms can be associated with some transformation of the phase space and functions defined on this phase space. We consider the Husimi functions QN(q, p) of N-quantum states of the harmonic oscillator, which are defined on the phase space, investigate transformation of these functions, and find an explicit form of the density matrix of the amplified N-photon state. © 2019, Springer Science+Business Media, LLC, part of Springer Nature.

60 APPLIED LIFE SCIENCES↗

Oscillating surge wave energy converter using a novel above-water power takeoff with belt-arc speed amplification

We investigate the performance of a novel power takeoff (PTO) featuring belt-arc speed amplification for oscillating surge wave energy converters (OSWECs), aiming to address the challenges of extremely low rotary speed and large torque under the low-frequency ocean wave excitations. The belt-arc design significantly increases the rotary speed of the generator, enabling generator downsizing and decreasing the powertrain friction losses. The design also allows for placing the generator above water, eliminating the need for high Ingress Protection ratings for the generator and powertrain, and potentially leading to substantial reductions in capital and maintenance costs. Using the linear potential wave theory, the dynamics of the integrated system are analyzed, and key parameters are identified. To validate the numerical analysis, a 1:10 scale model is designed, fabricated, and tested in a wave tank. Performance evaluations are conducted under regular and irregular wave conditions, with quantified effects of parameter tuning. The results reveal an optimal wave-to-electric efficiency of 48% under regular wave excitation and 20% under irregular excitation. Furthermore, these findings underscore the effectiveness of the proposed novel PTO design in addressing the challenges of low rotation speed and large torque inherent in OSWECs, demonstrating its ability to efficiently convert wave power into electricity.

16 TIDAL AND WAVE POWER↗

MTW-OPAL: a technology development platform for ultra-intense optical parametric chirped-pulse amplification systems

Optical parametric chirped-pulse amplification implemented using multikilojoule Nd:glass pump lasers is a promising approach for producing ultra-intense pulses (>10 23 W/cm 2 ). We report on the MTW-OPAL Laser System, an optical parametric amplifier line (OPAL) pumped by the Nd:doped portion of the multi-terawatt (MTW) laser. This midscale prototype was designed to produce 0.5-PW pulses with technologies scalable to tens of petawatts. Technology choices made for MTW-OPAL were guided by the longer-term goal of two full-scale OPALs pumped by the OMEGA EP to produce 2 × 25-PW beams that would be co-located with kilojoule–nanosecond ultraviolet beams. Several MTW-OPAL campaigns that have been completed since “first light” in March 2020 show that the laser design is fundamentally sound, and optimization continues as we prepare for “first-focus” campaigns later this year.

42 ENGINEERING↗