Search NASA⌕ Search

SEARCH · Search NASA

Results for “Asthma”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

81 records · Page 5
All sourcesNASA NTRSDOE OSTI
NASA NTRS2019

Noninvasive Breath Analysis Using NASA E-Nose Technology for Health Assessment

Clinical breath analysis is based on the fact that many important metabolites and biomarker molecules are present at detectable levels in exhaled breath, and many of these molecules correlate with human disease or correlate with physiological states that could lead to a decline in health. Presented is a technology that utilizes an array of chemical sensors combined with humidity, temperature and pressure for real time breath analysis to correlate the chemical information in the breath with the state and functioning of different human organs. For example, a marker for pulmonary inflammation processes of the lower respiratory tract, e.g. asthma, is the increase of the nitrogen oxide (NO) concentration in breath. Other volatile biomarkers may correlate with infectious process, metabolic conditions and inflammatory diseases, such as traumatic brain injury (TBI). This technology is also called "electronic nose" (E-Nose) in the sense that the device can mimic human nose to smell odors using a pattern recognition technique to analyze the sensor array data. Breath sampling is non-invasive and can be analyzed in real-time.

Li, Jing↗
NASA NTRS2020

DEVELOP Poster: Louisville Urban Development

Greenness and land surface temperature (LST) have been extensively correlated to urban public health. Chronic diseases such as diabetes, asthma, and cardiovascular illnesses have been linked to regions of high LST and areas lacking urban green spaces. One of our partners, the University of Louisville Envirome Institute, champions the importance of urban green spaces. Their research has pioneered efforts in increasing the area and accessibility of urban parks and greenspaces as a way to improve public health and combat environmental inequality. Louisville, Kentucky, is currently working to plant and manage urban trees. Our team used NASA Landsat 8 Operational Land Imager (OLI) and Thermal Infrared Sensor (TIRS) imagery to calculate the Normalized Difference Vegetation Index (NDVI) in Louisville at the census tract level and automated the process for use in other cities. The New York University School of Medicine’s City Health Dashboard displays public health metrics across 500 US cities and will use our methods to complete the NDVI analysis for all of these locations plus an additional 293 cities they are adding to their dashboard in the near future. Our NDVI and LST calculations will allow cites across the US to make informed decisions about reducing environmental inequality by focusing on areas with low NDVI and high LST.

Urban Development↗
NASA NTRS2020

Pacific Northwest Health & Air Quality - Utilizing NASA Earth Observations to Analyze Air Quality Impacts from Wildfires in the Pacific Northwest

The Pacific Northwest region of the United States and Canada has become more vulnerable to intense wildfire regimes due to years of fire suppression and climatic changes. Smoke from fires exposes communities to hazardous aerosols and pollutants known to trigger asthma symptoms and exacerbate other respiratory and cardiovascular diseases. In partnership with The Nature Conservancy’s Washington Chapter and the Puget Sound Clean Air Agency, NASA DEVELOP investigated the impacts of wildfire smoke on air quality from 2008 to 2020 using NASA Earth observations. To explore the various dimensions of smoke and its relation to air quality, the team looked at the vertical extent of smoke plumes and the resulting changes in air quality. The team evaluated the potential relationship between plume height of wildfire smoke and fire radiative power using the Moderate Resolution Imaging Spectroradiometer (MODIS) aboard the Aqua and Terra satellites and Terra’s Multi-angle Imaging SpectroRadiometer (MISR) using the MISR INteractive eXplorer (MINX). The team determined that there was no regional relationship between fire radiative power and smoke plume height. To investigate changes in air quality resulting from wildfire smoke, the team utilized data from NASA’s Fire Information for Resource Management System, from the European Space Agency’s Sentinel-5P Tropospheric Monitoring Instrument (TROPOMI), and true color imagery from Landsat 8 Operational Land Imager (OLI). The team created a Google Earth Engine-based (GEE) web tool to visualize changes in atmospheric pollutants and aerosol optical depth. Results of case study fires showed varying increases in pollutant concentrations when compared to a baseline map. The end products provided the partners with tools to quantify plume height using MINX and to visualize recent air quality patterns relating to variations in wildfire extent and severity in the Pacific Northwest

Ani Matevosian↗
NASA NTRS2021

Southeast Michigan Health & Air Quality: Identifying Trends of Ground-level Ozone Precursors in Southeast Michigan and Northern Ohio

Pollutants resulting from industrial activity can react with sunlight to create ground-level ozone, a harmful pollutant that can exacerbate respiratory health issues such as asthma. Due to a history of heavy industrialization, residents of southeast Michigan and northern Ohio are especially susceptible to ground-level ozone. NASA DEVELOP, in partnership with the Michigan Department of Environment, Great Lakes, and Energy’s (EGLE) Air Quality Division and the Lake Michigan Air Directors Consortium (LADCO), investigated the effectiveness of Earth observations (EO) in monitoring pollutants that contribute to ground-level ozone. The team used the European Space Agency’s TROPOspheric Monitoring Instrument (TROPOMI) aboard Sentinel-5P, and NASA’s Ozone Monitoring Instrument (OMI) aboard Aura, to measure nitrogen dioxide (NO2), formaldehyde (HCHO), and methane (CH4) from 2019 to 2021 (May-September). The team oversampled the EO data on monthly, yearly, and 3-year time scales where possible to enhance more localized pollutant trends. Specifically, TROPOMI effectively monitored NO2 from space, indicating sub-city distributions on a monthly timescale. Contrastingly, the measurements of HCHO were predominately noisy, and therefore failed to show any distribution trends. Lastly, CH4 trends were identifiable yet coarse, hinting that EO monitoring in the case of CH4 is not beneficial for our partners. The end products provide the partners with insight on the utility of EO in measuring certain ozone precursors and can be used to guide ground-level ozone reduction strategies throughout the region.

Mariam Moeen↗
NASA NTRS2021

Volatile Organic Compounds Emitted from Air Fresheners: Plug-Ins at Home and Little Trees in Cars

Air fresheners contain volatile organic compounds (VOCs), some of which are possible hazardous air pollutants, carcinogens, or chemicals associated with adverse health effects such as asthma. This screening study identifies VOCs emitted from two types of air fresheners. Plug-in air fresheners are household products that release scents from a heated liquid. Little Tree air fresheners are commonly used solid devices designed to hang in from the rear view mirror in cars. VOCs that were released from heated samples of air fresheners were identified by gas chromatography mass spectroscopy (GCMS). Amongst VOCs commonly known to have scent properties, this screening also revealed the presence of compounds that are not associated with fragrances and that may have adverse health effects. In a pilot study to characterize how air fresheners affect air quality in real settings, air samples were collected on solid-phase microextraction (SPME) field samplers in a home setting and inside a vehicle, before and during air-freshener use. This pilot demonstrated some limited potential for SPME field samplers to track changes in VOC levels in real-life settings.

Adriana Pino-Delgado↗
NASA NTRS2023

Health and Safety Effects of Airborne Soil Dust in the Americas and Beyond

Risks associated with dust hazards are often underappreciated, a gap between the knowledge pool and public awareness that can be costly for impacted communities. This study reviews the emission sources and chemical, physical, and biological characteristics of airborne soil particles (dust) and their effects on human and environmental health and safety in the Pan-American region. American dust originates from both local sources (western United States, northern Mexico, Peru, Bolivia, Chile, and Argentina) and long-range transport from Africa and Asia. Dust properties, as well as the trends and interactions with criteria air pollutants, are summarized. Human exposure to dust is associated with adverse health effects, including asthma, allergies, fungal infections, and premature death. In the Americas, a well-documented and striking effect of soil dust is its association with Coccidioidomycosis, commonly known as Valley fever, an infection caused by inhalation of soil-dwelling fungi unique to this region. Besides human health, dust affects environmental health through nutrients that increase phytoplankton biomass, contaminants that diminish water supply and affect food (crops/fruits/vegetables and ready-to-eat meat), spread crop and marine pathogens, cause Valley fever among domestic and wild animals, transport heavy metals, radionuclides and microplastics, and reduce solar and wind power generation. Dust is also a safety hazard to road transportation and aviation, in the southwestern US where blowing dust is one of the deadliest weather hazards. To mitigate the harmful effects, coordinated regional and international efforts are needed to enhance dust observations and prediction capabilities, soil conservation measures, and Valley fever and other disease surveillance.

health↗
DOE OSTI2020

Chapter 22 - Chlorine. In: “Handbook of Toxicology of Chemical Warfare Agents, Third Edition”, Editor: Ramesh C. Gupta.

Chlorine gas is used widely by industry and as a disinfectant and bleach, and, due to its toxicity and ease of procurement, has been used as a chemical warfare agent. Chlorine is a strong oxidizer that hydrolyzes in water to form hydrochloric and hypochlorous acid. Upon chlorine inhalation, the respiratory tract is the predominant target organ in humans and animals as chlorine is a contact irritant. Exposure causes sensory irritation and pulmonary dysfunction, and at sufficiently high concentrations results in lung lesions and injury to other internal organs including the heart. Human and animal studies have shown that chlorine toxicity is influenced more by exposure concentration than duration, is gender-independent, and increases with age, cigarette smoking, and preexisting respiratory conditions such as asthma and airway hyperreactivity. Treatment is largely supportive, although animal studies are examining the utility of various compounds for chlorine-specific treatment based on its mechanism of action.

Milanez, Sylvia↗
DOE OSTI2025

Burn parameters affect PAH emissions at conditions relevant for prescribed fires

Wildfire smoke is a health hazard as it contains carcinogenic volatile compounds and fine particulate matter. In particular, exposure to polycyclic aromatic hydrocarbons (PAHs) is a major concern, since these compounds have been recognized as important contributors to the overall carcinogenic risk. In this work, gas and particle-phase PAH emissions from combustion of Eastern White Pine (Pinus strobus) were quantified using time-of-flight mass spectrometry over a range of burn conditions representative of wildfires and prescribed fires, including fuel moisture, heat flux, and oxygen concentration. We found that changing the burn environment lead to a variability of up to 77% in phenanthrene/anthracene emissions. This could explain a large part of the variability in PAH emission factors from biomass combustion reported in the literature. Here, we found that optimal conditions for fuel moisture content of 20–30%, sample heat load of 60 - 70 kW m -2 , and oxygen concentrations of 5–15% can significantly reduce the emissions of heavy molar weight PAHs. Our analysis showed that the relative carcinogenic risk from PAH exposure can be reduced by more than 50% under optimal conditions. In light of the increasing use of prescribed fire for forest management, the relationship between emissions and burn conditions that we have established provides a guidance for assessing the expected health impact from prescription burns, and can inform strategies to reduce PAH emissions from prescribed fire activities.

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTAN↗
NASA NTRS2024

Chapter 9: Life as We Don't Know It

While Earth contains the only known example of life in the universe, it is possible that life elsewhere is fundamentally different from what we are familiar with. There is an increased recognition in the astrobiology community that the search for life should steer away from terran-specific biosignatures to those that are more inclusive to all life-forms. To start exploring the space of possibilities that life could occupy, we can try to dissociate life from the chemistry that composes it on Earth by envisioning how different life elsewhere could be in composition, lifestyle, medium, and form, and by exploring how the general principles that govern living systems on Earth might be found in different forms and environments across the Solar System. Exotic life-forms could exist on Mars or Venus, or icy moons like Europa and Enceladus, or even as a shadow biosphere on Earth. New perspectives on agnostic biosignature detection have also begun to emerge, allowing for a broader and more inclusive approach to seeking exotic life with unknown chemistry that is distinct from life as we know it on Earth.

Asthma↗