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Use of the NASA Space Radiation Laboratory at Brookhaven National Laboratory to Conduct Charged Particle Radiobiology Studies Relevant to Ion Therapy
Although clinical studies with carbon ions have been conducted successfully in Japan and Europe, the limited radiobiological information about charged particles that are heavier than protons remains a significant impediment to exploiting the full potential of particle therapy. There is growing interest in the U.S. to build a cancer treatment facility that utilizes charged particles heavier than protons. Therefore, it is essential that additional radiobiological knowledge be obtained using state-of-the-art technologies and biological models and end points relevant to clinical outcome. Currently, most such ion radiotherapy-related research is being conducted outside the U.S. This article addresses the substantial contributions to that research that are possible at the NASA Space Radiation Laboratory (NSRL) at Brookhaven National Laboratory (BNL), which is the only facility in the U.S. at this time where heavy-ion radiobiology research with the ion species and energies of interest for therapy can be done. Here in this paper, we briefly discuss the relevant facilities at NSRL and how selected charged particle biology research gaps could be addressed using those facilities.
Laboratories for the 21st Century: Best Practices; Energy Recovery in Laboratory Facilities [Brochure]
This guide regarding energy recovery is one in a series on best practices for laboratories. It was produced by Laboratories for the 21st Century ('Labs 21'), a joint program of the U.S. Environmental Protection Agency and the U.S. Department of Energy.
Argonne National Laboratory Annual Report of Laboratory Directed Research and Development Program Activities FY 2012
Our plans to upgrade the Advanced Photon Source are proceeding on schedule, and we hope to receive CD-2 approval sometime in spring 2013. When complete, the APS Upgrade will equip this vital facility for continued scientific leadership in the 21st century, providing the 5,000-plus members of our user community with greatly increased time, energy and spatial resolution. We also have successfully installed “Mira,” the new IBM Blue Gene/Q system at the Argonne Leadership Computing Facility. The world’s fourth-fastest supercomputer, Mira is now providing leading-edge computational power across all scientific disciplines. I am also pleased to report that Argonne’s new Energy Sciences Building is proceeding on schedule; we expect it to be finished and ready for occupancy by June 30, 2013. When complete, the ESB will be one of the most modern and most flexible energy labs in the world, creating a new home for researchers focused on a wide range of energy science challenges. Research is under way at the new multidisciplinary Institute for Molecular Engineering (IME), a joint program of the University of Chicago and Argonne. Over the past year, four new faculty members, including IME’s director, – all pre-eminent researchers who hold joint appointments at Argonne – have joined the IME. We look forward to working in collaboration with the IME to find new ways to address the interfaces between molecular-level science and powerful new technologies. In FY 2012, we continued support for the final year of the “Beyond Lithium-Ion” Director’s Grand Challenge LDRD project. That project enabled significant work on the performance of lithium-based energy storage systems, pointing the way to new high-energy-density lithium-air batteries. I believe this Grand Challenge contributed significantly to our successful bid to win designation of the Argonne-based Joint Center for Energy Storage Research (JCESR) as the DOE’s new Batteries and Energy Storage Hub. JCESR, which brings together a world-class “dream team” of national laboratories, universities and private sector partners, strongly benefited from LDRD program investments, both in FY2012 and in previous years. As we move forward in FY2013, the Director’s Grand Challenge is now focused on new ways to address the challenges of “big data” – the acquisition, storage, transfer, and analysis of both experimental and simulated data at scales approaching the limits of our current computational capacities. In managing Argonne’s LDRD program, we have adhered to the requirements of DOE Order 413.2b and associated guidelines. Our program management continually strives for increased efficiency. In addition to meeting all reporting requirements during FY 2012, our LDRD Program Office continues to implement intranet-based process enhancements to better serve all LDRD stakeholders, including our DOE Site Office colleagues. As the following individual project reports demonstrate, Argonne’s researchers are pursuing projects at the leading edge of science and engineering, and making significant contributions to the advancement of our laboratory’s major strategic initiatives. Evidence of the continuing strength of this program is found in the follow-on sponsorship won by many of these research projects, as well as in the numbers of publications, invited presentations, inventions, and new staff hires that are direct results of LDRD. LDRD enables exploration of new scientific directions and makes it possible to adapt quickly to a changing landscape with unexpected opportunities, while enhancing the capabilities of our researchers and our scientific facilities. For these reasons, LDRD remains an invaluable resource to address the future science and technology needs of DOE, and of our nation.
Energy and Water Conservation Assessment of the Radiochemical Processing Laboratory (RPL) at Pacific Northwest National Laboratory
This report summarizes the results of an energy and water conservation assessment of the Radiochemical Processing Laboratory (RPL) at Pacific Northwest National Laboratory (PNNL). The assessment was performed in October 2013 by engineers from the PNNL Building Performance Team with the support of the dedicated RPL staff and several Facilities and Operations (F&O) department engineers. The assessment was completed for the Facilities and Operations (F&O) department at PNNL in support of the requirements within Section 432 of the Energy Independence and Security Act (EISA) of 2007.
Argonne National Laboratory Annual Report of Laboratory Directed Research and Development Program Activities FY 2014
Every day, scientists and engineers at Argonne National Laboratory make impor-tant discoveries that translate into a real difference in the world, working towards the Lab’s mission to develop energy solutions, preserve the environment, pro-tect the nation, and help the economy thrive.Argonne’s Laboratory Directed Research and Development (LDRD) program is key to advancing our leadership in science and technology and enables us to explore new ideas, build new capabilities, and address emerging research opportunities.LDRD is an invaluable resource for contributing to the future science and tech-nology needs of DOE and the nation. It helps us investigate new directions for Department programs while being able to adapt to new opportunities in a changing environment. Equally crucially, it serves to maintain and enhance the capabilities of both our staff and our R&D facilities.
Argonne National Laboratory Annual Report 2016 of Laboratory Directed Research and Development Program Activities
Argonne National Laboratory, as a U.S. Department of Energy (DOE) national laboratory, is dedicated to advancing the energy frontier through science and technology.
Lawrence Livermore National Laboratory FY 2016 Laboratory Directed Research and Development Annual Report
The LDRD annual report for FY2016 consists of two parts: The Overview. This section contains a broad description of the LDRD Program, highlights of recent accomplishments and awards, Program statistics, and the LDRD portfolio-management processes. Project Reports. Project reports are submitted by all principal investigators at the end of the fiscal year. The length and depth of the report depends on the project’s lifecycle. For projects that will be continuing the following year, the principal investigator submits a continuing project report, which is a brief update containing descriptions of the goals, scope, motivation, relevance (to DOE/NNSA and Livermore mission areas), and technical progress achieved in FY16, as well as a list of selected publications and presentations that resulted from the research. For projects that concluded in FY16, a more detailed final report is provided that is technical in nature and includes the background, objectives, scientific approach, accomplishments, and impacts on the Laboratory missions, as well as a list of publications and presentations that resulted from the research. Project reports are listed under their research topics and organized by year and type, such as exploratory research (ER), feasibility study (FS), laboratory-wide competition (LW), and strategic initiative (SI). Each project is assigned a unique tracking code, an identifier that consists of three elements. The first is the fiscal year in which the project began, the second represents the project type, and the third identifies the serial number of the project for that fiscal year. For example, 16-ERD-100 means the project is an exploratory research project that began in FY16. The three-digit number (100) represents the serial number for the project.
Abstract - Cooperative Research and Development Agreement between Ames National Laboratory and National Energy Technology Laboratory AGMT-0609
The goal of this project is to develop a merged environment for simulation and analysis (MESA) at the National Energy Technology Laboratory’s (NETL) Hybrid Performance (Hyper) project laboratory. The MESA sensor lab developed as a component of this research will provide a development platform for investigating: 1) advanced control strategies, 2) testing and development of sensor hardware, 3) various modeling in-the-loop algorithms and 4) other advanced computational algorithms for improved plant performance using sensors, real-time models, and complex systems tools.
Start your career at Los Alamos National Laboratory in the Associate Laboratory Directorate for Weapons Production [Slides]
Los Alamos National Laboratory (LANL) is the place for early-career professionals to join our crucial mission in support of national security. In the Associate Laboratory Directorate for Weapons Production (ALDWP) you will find a diverse workplace with roles of all kinds and endless upward momentum for a long-lasting and ever-changing career!
Consequences of CCD imperfections for cosmology determined by weak lensing surveys: from laboratory measurements to cosmological parameter bias
Weak gravitational lensing causes subtle changes in the apparent shapes of galaxies due to the bending of light by the gravity of foreground masses. By measuring the shapes of large numbers of galaxies (millions in recent surveys, up to tens of billions in future surveys) we can infer the parameters that determine cosmology. Imperfections in the detectors used to record images of the sky can introduce changes in the apparent shapes of galaxies, which in turn can bias the inferred cosmological parameters. In this paper we consider the effect of two widely discussed sensor imperfections: tree rings, due to impurity gradients that cause transverse electric fields in the charge-coupled devices (CCDs), and pixel size variation, due to periodic CCD fabrication errors. These imperfections can be observed when the detectors are subject to uniform illumination (flat-field images). We develop methods to determine the spurious shear and convergence (due to the imperfections) from the flat-field images. We calculate how the spurious shear when added to the lensing shear will bias the determination of cosmological parameters. We apply our methods to candidate sensors of the Large Synoptic Survey Telescope (LSST) as a timely and important example, analyzing flat-field images recorded with LSST prototype CCDs in the laboratory. We find that tree rings and periodic pixel size variation present in the LSST CCDs will introduce negligible bias to cosmological parameters determined from the lensing power spectrum, specifically w, Ω{sub m}, and σ{sub 8}.
DESIGN OF LABORATORY EXPERIMENTS TO STUDY PHOTOIONIZATION FRONTS DRIVEN BY THERMAL SOURCES
This paper analyzes the requirements of a photoionization-front experiment that could be driven in the laboratory, using thermal sources to produce the necessary flux of ionizing photons. It reports several associated conclusions. Such experiments will need to employ the largest available facilities, capable of delivering many kJ to MJ of energy to an X-ray source. They will use this source to irradiate a volume of neutral gas, likely of N, on a scale of a few mm to a few cm, increasing with source energy. For a gas pressure of several to ten atmospheres at room temperature, and a source temperature near 100 eV, one will be able to drive a photoionization front through a system of tens to hundreds of photon mean free paths. The front should make the familiar transition from the so-called R-Type to D-Type as the radiation flux diminishes with distance. The N is likely to reach the He-like state. Preheating from the energetic photons appears unlikely to become large enough to alter the essential dynamics of the front beyond some layer near the surface. For well-chosen experimental conditions, competing energy transport mechanisms are small.
An Atmospheric Cloud Physics Laboratory for the Space Laboratory
Results of research and engineering analyses to date show that it is feasible to develop and fly on the first Spacelab mission a multipurpose laboratory in which experiments can be performed on the microphysical processes in atmospheric clouds. The paper presents a series of tables on the Atmospheric Cloud Physics Laboratory, with attention given to experiment classes, the preliminary equipment list (particle generators, optical and imaging devices, particle detectors and characterizers, etc.), initial equipment (scientific equipment subsystems and flight support subsystems), and scientific functional requirements (the expansion chamber, the continuous flow diffusion chamber, the static diffusion chamber, the humidifier, and particle generators).
CheMin: A Definitive Mineralogy Instrument in the Analytical Laboratory of the Mars Science Laboratory (MSL '09)
An important goal of the Mars Science Laboratory (MSL 09) mission is the determination of definitive mineralogy and chemical composition. CheMin is a miniature X-ray diffraction/X-ray fluorescence (XRD/XRF) instrument that has been chosen for the analytical laboratory of MSL. CheMin utilizes a miniature microfocus source cobalt X-ray tube, a transmission sample cell and an energy-discriminating X-ray sensitive CCD to produce simultaneous 2-D X-ray diffraction patterns and X-ray fluorescence spectra from powdered or crushed samples. A diagrammatic view of the instrument is shown.
CheMin: A Definitive Mineralogy Instrument in the Analytical Laboratory of the Mars Science Laboratory
An important goal of the Mars Science Laboratory (MSL '09) mission is the determination of definitive mineralogy and chemical composition. CheMin is a miniature X-ray diffraction/X-ray fluorescence (XRD/XRF) instrument that has been chosen for the analytical laboratory of MSL. CheMin utilizes a miniature microfocus source cobalt X-ray tube, a transmission sample cell and an energy-discriminating X-ray sensitive CCD to produce simultaneous 2-D X-ray diffraction patterns and X-ray fluorescence spectra from powdered or crushed samples. A diagrammatic view of the instrument is shown. Additional information is included in the original extended abstract.
Laboratory-scale quartz crucible melter tests for vitrifying a high-MoO3 raffinate waste simulant
Not Available
Idaho National Laboratory Ten-Year Site Plan Project Description Document: Descriptions of the capital projects delineated in the Idaho National Laboratory 2013 - 2022 Ten-Year Site Plan as of June 2011
This document describes the currently active and proposed infrastructure projects listed in Appendix B of the Idaho National Laboratory 2013-2022 Ten Year Site Plan (DOE/ID-11449). It was produced in accordance with Contract Data Requirements List I.06. The projects delineated in this document support infrastructure needs at INL's Research and Education Campus, Materials and Fuels Complex, Advanced Test Reactor Complex and the greater site-wide area. The projects provide critical infrastructure needed to meet current and future INL operational and research needs. Execution of these projects will restore, rebuild, and revitalize INL's physical infrastructure; enhance program execution, and make a significant contribution toward reducing complex-wide deferred maintenance.
Voyager capsule, preliminary design, phase B. Volume III - Surface laboratory system. Section I - Surface laboratory Final report
Surface Laboratory preliminary configuration for Voyager mission - space capsule