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Results for “OXYGEN CONSUMPTION”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 91 records · Page 5

Potato respirometer experiment SO61

The design and manufacture of a respirometer for measuring the oxygen consumption rate of a respiring potato sprout in a Skylab experiment is reported. The device monitors low gravity effects on the biorhythmicity of organisms during space flight. Several experimental runs using bench mounted flight hardware units were inconclusive due to room temperature induced artifacts.

Taudvin, P. C.↗

Rare-gas effects on metabolism and inert gas narcosis

The detailed examination is reported of the theory that narcosis results from expansion of the cell membrane under high partial pressures. The research is partially based on the hypothesis that, like oxygen toxicity, the mechanism of metabolic effects of rare gases may be similar at both low and high pressures and are simply more observable at high pressures. Using adult female goats, the parameters measured include oxygen consumption, CO2 production, respiration rate, heart rate, rectal and skin temperatures and the analysis of electroencephalograms and evoked response. Additionally, the specific activity is measured of plasma glucose subsequent to injection of glucose-UL-C-14, intravenous infusion, specific activity of expired CO2, unesterified fatty acid levels and whole blood lactate-to-pyruvate ratios. Also studied were the effects of acetylsalicylic acid, vitamin E and cationic detergents (which alleviate narcosis) upon metabolic changes induced by high pressure narcosis.

Source record↗

Respiratory weight losses during exercise.

Evaporative water loss from the respiratory tract was determined over a wide range of exercise. The absolute humidity of the expired air was the same at all levels of exercise and equal to that measured at rest. The rate of respiratory water loss during exercise was found to be 0.019 of the oxygen uptake times (44 minus water vapor pressure). The rate of weight loss during exercise due to CO2-O2 exchange was calculated. For exercise at oxygen consumption rates exceeding 1.5 L/min in a dry environment with a water vapor pressure of 10 mm Hg, the total rate of weight loss via the respiratory tract is on the order of 2-5 g/min.

Mitchell, J. W.↗

Cardiac beta-adrenergic receptors and coronary hemodynamics in the conscious dog during hypoxic hypoxia.

The mechanisms by which acute hypoxia (10% and 5% oxygen) mediates changes in coronary blood flow and cardiac function were investigated in the conscious dog. When the dogs breathed hypoxic gas mixtures through a tracheostomy, both arterial and coronary sinus oxygen tensions were significantly decreased. With 5% oxygen, there were significant increases in heart rate (25%), maximum left ventricular dP/dt (39%), left circumflex coronary artery blood flow (163%), and left ventricular oxygen consumption (52%), which were attenuated by beta-adrenergic blockage with propranolol. When electrical pacing was used to keep the ventricular rate constant during hypoxia, there was no significant difference in coronary blood flow before and after beta blockade. Beta-adrenergic receptor activity in the myocardium participates in the integrated response to hypoxia although it may not cause active vasodilation of the coronary vessels.

Erickson, H. H.↗

Brain calcium - Role in temperature regulation.

Perfusion of the preoptic-anterior hypothalamus with excess calcium ion in ground squirrels produces a drop in core temperature. The magnitude of the drop is directly dependent on ambient temperature. Respiration, heart rate, and oxygen consumption are also reduced during perfusion of calcium ion. It is concluded that the depression of body temperature during calcium ion perfusion is due to generalized depression of the neurons of the preoptic-anterior hypothalamus.

Hanegan, J. L.↗

Metabolic analyzer

An apparatus is described for the measurement of metabolic rate and breathing dynamics in which inhaled and exhaled breath are sensed by sealed, piston-displacement type spirometers. These spirometers electrically measure the volume of inhaled and exhaled breath. A mass spectrometer analyzes simultaneously for oxygen, carbon dioxide, nitrogen, and water vapor. Circuits responsive to the outputs of the spirometers, mass spectrometer, temperature, pressure, and timing signals compute oxygen consumption, carbon dioxide production, minute volume, and respiratory exchange ratio. A selective indicator provides for readout of these data at predetermined cyclic intervals.

Perry, C. L.↗

Metabolic analyzer

An apparatus is described for the measurement of metabolic rate and breathing dynamics in which inhaled and exhaled breath are sensed by sealed, piston-displacement type spirometers. These spirometers electrically measure the volume of inhaled and exhaled breath. A mass spectrometer analyzes simultaneously for oxygen, carbon dioxide, nitrogen and water vapor. Computation circuits are responsive to the outputs of the spirometers, mass spectrometer, temperature, pressure and timing signals and compute oxygen consumption, carbon dioxide production, minute volume and respiratory exchange ratio. A selective indicator provides for read-out of these data at predetermined cyclic intervals.

Rummel, J. A.↗

Cycles in metabolism and heat loss

Using calorimetric techniques, subjects' metabolism, thermoregulation, and body temperatures were monitored continuously for 24-hour days, using three types of experimental routines. A water cooling garment (WCG) was used for direct calorimetry, while partitional calorimetry was used to establish a non-suited comparison for one of the routines. In this replicated routine, called the quiet day, the subjects were sedentary throughout the daytime hours and slept normally at night. Results indicate that the WCG may act to reduce 24-hour total oxygen consumption (VO2) or heat production, possibly due to the lowered energy cost of thermoregulation.

Annis, J. F.↗

An environmental chamber system for prolonged metabolic studies on small animals

Measurement of metabolic adaptation to marginally stressful environments requires both precise regulation of a variety of atmospheric factors for extended periods of time and the capacity to employ sensitive parameters in an undisturbed subject. This paper describes a metabolic chamber system which can simultaneously maintain groups of small animals in two completely separate closed environments having different pressures, temperatures and gas compositions for an indefinite period. Oxygen consumption, carbon dioxide production, food and water consumption and animal activity cycles can be continuously monitored and quantified 24 h per day while the animals are in an unrestrained state. Each chamber can be serviced and the animals handled, injected and sacrificed without subjecting them to barometric stress. Several unique electrical and mechanical components allow semi-automated data collection on a continuous basis for indefinite periods of time.

Jordan, J. P.↗

Gravitational considerations with animal rhythms

As established in the laboratory and largely confirmed by others, simulated high-g environments influence growth and development of animals as small as or smaller than baby turtles, sometimes accelerating and sometimes decelerating these processes. High-g environments result in many functional changes or adjustments in feeding, metabolism, circulation, fluid balances, and structures for support, and influence life expectancy. An assembly of equipment suitable for measuring oxygen consumption of small mammals as influenced by chronic centrifugation and/or by day-night rhythms is discussed.

Wunder, C. C.↗