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GeneLab: Open Science For Exploration

The NASA GeneLab project capitalizes on multi-omic technologies to maximize the return on spaceflight experiments. The GeneLab project houses spaceflight and spaceflight-relevant multi-omics data in a publicly accessible data commons, and collaborates with NASA-funded principal investigators to maximize the omics data from spaceflight and spaceflight-relevant experiments. I will discuss the current status of GeneLab and give specific examples of how the GeneLab data system has been used to gain insight into how biology responds to spaceflight conditions.

Omics

GeneLab: Open Science for Life in Space

The NASA GeneLab project capitalizes on multi-omic technologies to maximize the return on spaceflight experiments. To do this, GeneLab maintains a publicly accessible database (GLDS) that houses spaceflight and spaceflight relevant multi-omics data, and collaborates with NASA principal investigators and projects to generate additional omics data. GeneLab houses more than 200 transcriptomic, proteomic, metabolomic and epigenomic datasets from plant, animal and microbial experiments, with a growing number of these having been produced by the GeneLab sample processing lab. The GLDS contains rich metadata about each experiment and has recently integrated radiation dosimetery data from experiments flown on the Space Shuttle. GeneLab has also recently implemented an effort to present processed data in the GLDS in addition to the raw omics data. The processed data will enable interpretation of the data by a larger group of students, scientists and the general public. Standard pipelines for the transformation of raw data into visualizations were developed by four GeneLab Analysis Working Groups (animals, plants, microbes, multi-omics) comprised of over 100 scientists from NASA and academia. These pipelines are now being used by a group of bioinformatics interns to provide standard basic analysis of the data for incorporation into GLDS.

Galazka, Jonathan M.

Landsat 9: Empowering Open Science and Applications Through Continuity

The history of Earth observation from space is well reflected through the Landsat program. With data collection beginning with Landsat-1 in 1972, the program has evolved technical capabilities while maintaining continuity of land observations. In so doing, Landsat has provided a critical reference for assessing long-term changes to Earth's land environment due to both natural and human forcing. Poised for launch in mid-2021, the joint NASA-USGS Landsat 9 mission will continue this important data record. In many respects Landsat 9 is a clone of Landsat-8. The Operational Land Imager-2 (OLI-2) is largely identical to Landsat 8 OLI, providing calibrated imagery covering the solar reflected wavelengths. The Thermal Infrared Sensor-2 (TIRS-2) improves upon Landsat 8 TIRS, addressing known issues including stray light incursion and a malfunction of the instrument scene select mirror. In addition, Landsat 9 adds redundancy to TIRS-2, thus upgrading the instrument to a 5-year design life commensurate with other elements of the mission. Initial performance testing of OLI-2 and TIRS-2 indicate that the instruments are of excellent quality and expected to match or improve on Landsat 8 data quality. Landsat-9 will maintain the current data acquisition rate of up to 740 scenes per day, with these scenes available from the Landsat archive at no cost to users. In this communication, we provide background and rationale for the Landsat 9 mission, describe the instrument payloads and ground system, and discuss data products available from the Landsat 9 mission through USGS.

Jeffrey G. Masek

Open Science and AI

Explore the source record for details and available documents.

Rahul Ramachandran

NASA GeneLab: Open Science for Life in Space

The NASA GeneLab project (genelab.nasa.gov) seeks to get the most from space-relevant biology experiments by providing and maintaining a public database consisting of DNA, RNA, protein, and metabolite data from spaceflight experiments. Since these types of data, referred to as omics data, are difficult to understand for non-bioinformaticians, the GeneLab data processing team works with the scientific community to develop methods to process these data. The processed data found on GeneLab reveals information about which genes are turned on and turned off in the space environment, which helps us understand how space changes our biology and how we can best mitigate these effects to travel deeper into space.

Jonathan Oribello