ALP explanation to the muon ( g − 2 ) and its test at future Tera- Z and Higgs factories
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Calcium-aluminum–rich inclusions (CAIs) in meteorites carry crucial information about the environmental conditions of the nascent Solar System prior to planet formation. Based on models of 50V– 10 Be co-production by in-situ irradiation, CAIs are considered to have formed within ~0.1 AU from the proto-Sun. Here, we present vanadium (V) and strontium (Sr) isotopic co-variations in fine- and coarse-grained CAIs and demonstrate that kinetic isotope effects during partial condensation and evaporation best explain V isotope anomalies previously attributed to solar particle irradiation. We also report initial excesses of 10 Be and argue that CV CAIs possess essentially a homogeneous level of 10 Be, inherited during their formation. Based on numerical modeling of 50V–10Be co-production by irradiation, we show that CAI formation during protoplanetary disk build-up likely occurred at greater heliocentric distances than previously considered, up to planet-forming regions (~1AU), where solar particle fluxes were sufficiently low to avoid substantial in-situ irradiation of CAIs.
The Ghost Collider is an innovative proposal for a 550 GeV centre-of-mass, 275 GeV per beam linear collid-er with four interaction regions, each with the design luminosity. The primary innovation is the use of “ghost bunches” containing equal numbers of electrons and posi-trons so they are electrically neutral. In the linacs, energy is transferred between electrons and positrons in the same bunch, decelerating one type of particle and using the energy to accelerate the other: a new class of Energy Re-covery Linacs. At the interaction points, collisions be-tween two neutral ghost bunches occurs with weakened electromagnetic interaction such as the beam-beam effect or disruption, ensuring that the particles and their energy can be recycled with minimal loss. Four “serial IPs” are incorporated, where chromatic errors produced in one IP are cancelled in the following IP. The neutral beam insta-bility at the IP is also addressed. All interaction points have the nominal luminosity per IP of 2.8 x 1034 cm-2s-1 for a facility luminosity of 1.1 x1035 cm-2s-1 @ 100 MW electrical power for the RF systems. The result is a totally original concept for an electron-positron collider.
Rotating algae biofilm reactors (RABRs) can reduce energy requirements for wastewater reclamation but require further optimization for implementation at water resource recovery facilities (WRRF). Optimizing RABR operation is challenging because conditions at WRRF change frequently, and disregarding interaction terms related to these changes can produce incorrect conclusions about RABR behavior. This study evaluated the two-way interaction and main effects of four factors on the biomass productivity and phosphorus removal efficiency of a microalgae-bacteria biofilm grown in municipal anaerobic digester centrate, with factor levels and operating conditions selected to mimic a pilot RABR at a WRRF in Utah. Two-way interactions harvesting period*light intensity (LI), harvesting period*temperature, and LI*hydraulic retention time (HRT) had significant effects on biomass productivity: at high temperature and low LI, highest biomass productivity was achieved with a 14-day harvesting period, but at medium temperature and high LI, highest biomass productivity was achieved with a 7-day harvesting period. At high HRT, highest biomass productivity occurred at low LI, but at low HRT, highest biomass productivity occurred at high LI. Phosphorus removal was strongly influenced by LI and occurred most rapidly during the first 2 days HRT, which suggests precipitation contributed significantly to phosphorus removal. These observations provide insight for further RABR optimization.
The potential for new, re-emerging, or engineered pandemic threats could challenge our nation's biosecurity, requiring rapid and flexible countermeasure development platforms. In healthcare, one of the main hindrances to the timely development of protein-based therapeutics for cancer, infectious disease, and other diseases has been a slow and expensive quality-controlled production stage. We present a protein-based technology that has the potential to address these crucial problems in biosecurity and healthcare by maximizing protein production and system portability, while minimizing production latency and cost. Specifically, we have developed a reusable, portable first-generation platform that leverages the advantages of cell-free protein synthesis (CFPS) and flow cells to create practical amounts of clinically relevant therapeutics. We have demonstrated that this technology is reusable and programmable, enabling a single platform that can synthesize multiple dosages of various therapeutics and vaccine in the field. Implementing this technology could mitigate pandemic threats by providing a rapidly-deployable (just-in-time), versatile (precision medicine) production of biologic therapeutics to the infected patient’s locale (point-of-care). In drug development, once promising drug variations are identified, the platform can be scaled to quickly produce practical amounts of protein for patient testing in the matter of days (vs. months) at a fraction of the cost of existing technology.
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This technical report describes an implementation of a scalable continuous integration/continuous deployment infrastructure using Microsoft Azure™ and GitLab™ resources. We utilize GitLab continuous integration podman executors to provide rootless container operations in both privileged and unprivileged modes of operation. We utilize the GitLab Fleeting plugin for Azure to manage the scaling of continuous integration execution resources. This creates a scalable, rootless, and isolate continuous integration/continuous deployment job execution infrastructure.
This report briefly summarizes the spectroradiometric approach adapted and deployed as part of Task 4.2 within the BETO-funded D evelopment of I ntegrated S creening, C ultivar O ptimization, and V erification R esearch (DISCOVR) project, specifically task 4, “Increase crop protection and culture stability.” The goals of this subtask were to monitor ponds cultivating a variety of DISCOVR strains at the Arizona Center for Algae Technology and Innovation (AzCATI) with spectroradiometric technology to: • Predict biomass concentrations with high temporal frequency. • Optimize automated analysis methods that enabled feedback for pond automation strategies • Identify pond crash indicators from primary (pest/predator) and indirect (change in algal host) spectroscopic signals with potential for early treatment/intervention • Provide recommendations for technology deployment at scale. This report fulfills the deliverable requirement for the final bullet “provide recommendations for technology deployment at scale”.
Biofuels and other biologically manufactured sustainable goods are growing in popularity and demand. Carbohydrate feedstocks required for industrial fermentation processes have traditionally been supplied by plant biomass, but the large quantities required to produce replacement commodity products may prevent the long-term feasibility of this approach without alternative strategies to produce sugar feedstocks. Cyanobacteria are under consideration as potential candidates for sustainable production of carbohydrate feedstocks, with potentially lower land and water requirements relative to plants. Several cyanobacterial strains have been genetically engineered to export significant quantities of sugars, especially sucrose. Sucrose is not only naturally synthesized and accumulated by cyanobacteria as a compatible solute to tolerate high salt environments, but also an easily fermentable disaccharide used by many heterotrophic bacteria as a carbon source. In this review, we provide a comprehensive summary of the current knowledge of the endogenous cyanobacterial sucrose synthesis and degradation pathways. We also summarize genetic modifications that have been found to increase sucrose production and secretion. Finally, we consider the current state of synthetic microbial consortia that rely on sugar-secreting cyanobacterial strains, which are co-cultivated alongside heterotrophic microbes able to directly convert the sugars into higher-value compounds (e.g., polyhydroxybutyrates, 3-hydroxypropionic acid, or dyes) in a single-pot reaction. We summarize recent advances reported in such cyanobacteria/heterotroph co-cultivation strategies and provide a perspective on future developments that are likely required to realize their bioindustrial potential.
X-ray observations of low-mass stars in open clusters are critical to understanding the dependence of magnetic activity on stellar properties and their evolution. Praesepe and the Hyades, two of the nearest, most-studied open clusters, are among the best available laboratories for examining the dependence of magnetic activity on rotation for stars with masses ≲1 M ⊙ . We present an updated study of the rotation–X-ray activity relation in the two clusters. We updated membership catalogs that combine pre-Gaia catalogs with new catalogs based on Gaia Data Release 2. The resulting catalogs are the most inclusive ones for both clusters: 1739 Praesepe and 1315 Hyades stars. We collected X-ray detections for cluster members, for which we analyzed, re-analyzed, or collated data from ROSAT, the Chandra X-ray Observatory, the Neil Gehrels Swift Observatory, and XMM-Newton. We have detections for 326 Praesepe and 462 Hyades members, of which 273 and 164, respectively, have rotation periods—an increase of 6× relative to what was previously available. We find that at ≈700 Myr, only M dwarfs remain saturated in X-rays, with only tentative evidence for supersaturation. We also find a tight relation between the Rossby number and fractional X-ray luminosity L X /L bol in unsaturated single members, suggesting a power-law index between –3.2 and –3.9. Lastly, we find no difference in the coronal parameters between binary and single members. These results provide essential insight into the relative efficiency of magnetic heating of the stars' atmospheres, thereby informing the development of robust age-rotation-activity relations.
We discuss considerations that can be used to formulate recommendations for initiating a lepton collider project that would provide precision studies of the Higgs boson and related electroweak phenomena.
The overall objective of this project is to develop a low-cost, efficient, and reliable MWe-class Solid Oxide Fuel Cell (SOFC) power system towards commercial deployment in natural-gas fueled distributed generation applications. This report details the successful completion of all project objectives. The main goals of the project were to develop the conceptual design of a MWe-class SOFC power system, and to complete a techno-economic analysis (TEA) to determine system costs at low-volume production levels of >100MW per year. The combination of the BoP equipment cost and SOFC stack module factory cost provided the net fabrication cost of the selected 1MW SOFC system configuration. The results of the study showed that the cost target of less than $6000/kW is achievable for a FOAK 1MW SOFC system, exclusive of the first-time engineering cost. Also, the project included an exploratory analysis of the factory cost of next generation stack technology based on the Compact Solid-oxide Architecture (CSA) design at a high annual manufacturing rate of one-GW produced in a giga-factory. The BoP capital cost for one giga-watt power production was estimated using learning-curve analysis based on the historical manufacturing cost data related to similar high temperature Molten Carbonate fuel cell systems built by FuelCell Energy (FCE). The giga-factory manufactured SOFC cost estimate combined with the BoP cost at high production rates led to the estimation of entire system capital cost. Ultimately, a Cost of Electricity (COE) analysis was performed including natural gas fuel prices, installation and O&M costs, and stack replacement cost. The results of the techno-economic analysis were summarized by parametric estimation of COE for 1MW SOFC NOAK (Nth-of-a-Kind) system with natural gas prices as a variable parameter.