Search NASA⌕ Search

SEARCH · Search NASA

Results for “find”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 91 records · Page 5

Analysis of Phoenix Anomalies and IV and V Findings Applied to the GRAIL Mission

Analysis of patterns in IV&V findings and their correlation with post-launch anomalies allowed GRAIL to make more efficient use of IV&V services . Fewer issues. . Higher fix rate. . Better communication. . Increased volume of potential issues vetted, at lower cost. . Hard to make predictions of post-launch performance based on IV&V findings . Phoenix made sound fix/use as-is decisions . Things that were fixed eliminated some problems, but hard to quantify. . Broad predictive success in one area, but inverse relationship in others.

Gravity Recovery and Interior Laboratory (GRAIL)↗

The Gemini NICI Planet-Finding Campaign: The Offset Ring of HR 4796 A

We present J, H, CH4 short (1.578 micrometers), CH4 long (1.652 micrometers) and K(sub s)-band images of the dust ring around the 10 Myr old star HR 4796 A obtained using the Near Infrared Coronagraphic Imager (NICI) on the Gemini-South 8.1 m Telescope. Our images clearly show for the first time the position of the star relative to its circumstellar ring thanks to NICI's translucent focal plane occulting mask. We employ a Bayesian Markov chain Monte Carlo method to constrain the offset vector between the two. The resulting probability distribution shows that the ring center is offset from the star by 16.7 +/- 1.3 milliarcseconds along a position angle of 26 +/- 3deg, along the PA of the ring, 26.47 +/- 0.04deg. We find that the size of this offset is not large enough to explain the brightness asymmetry of the ring. The ring is measured to have mostly red reflectivity across the JHKs filters, which seems to indicate micron-sized grains. Just like Neptune's 3:2 and 2:1 mean-motion resonances delineate the inner and outer edges of the classical Kuiper belt, we find that the radial extent of the HR 4796 A and the Fomalhaut rings could correspond to the 3:2 and 2:1 mean-motion resonances of hypothetical planets at 54.7 AU and 97.7 AU in the two systems, respectively. A planet orbiting HR 4796 A at 54.7 AU would have to be less massive than 1.6 Jup mass so as not to widen the ring too much by stirring.

Near Infrared Coronagraphic Imager (NICI)↗

Findings from the Supersonic Qualification Program of the Mars Science Laboratory Parachute System

In 2012, the Mars Science Laboratory Mission (MSL) will deploy NASA's largest extra-terrestrial parachute, a technology integral to the safe landing of its advanced robotic explorer on the surface. The supersonic parachute system is a mortar deployed 21.5 m disk-gap-band (DGB) parachute, identical in geometric scaling to the Viking era DGB parachutes of the 1970's. The MSL parachute deployment conditions are Mach 2.3 at a dynamic pressure of 750 Pa. The Viking Balloon Launched Decelerator Test (BLDT) successfully demonstrated a maximum of 700 Pa at Mach 2.2 for a 16.1 m DGB parachute in its AV4 flight. All previous Mars deployments have derived their supersonic qualification from the Viking BLDT test series, preventing the need for full scale high altitude supersonic testing. The qualification programs for Mars Pathfinder, Mars Exploration Rover, and Phoenix Scout Missions were all limited to subsonic structural qualification, with supersonic performance and survivability bounded by the BLDT qualification. The MSL parachute, at the edge of the supersonic heritage deployment space and 33% larger than the Viking parachute, accepts a certain degree of risk without addressing the supersonic environment in which it will deploy. In addition, MSL will spend up to 10 seconds above Mach 1.5, an aerodynamic regime that is associated with a known parachute instability characterized by significant canopy projected area fluctuation and dynamic drag variation. This aerodynamic instability, referred to as "area oscillations" by the parachute community has drag performance, inflation stability, and structural implications, introducing risk to mission success if not quantified for the MSL parachute system. To minimize this risk and as an alternative to a prohibitively expensive high altitude test program, a multi-phase qualification program using computation simulation validated by subscale test was developed and implemented for MSL. The first phase consisted of 2% of fullscale supersonic wind tunnel testing of a rigid DGB parachute with entry-vehicle to validate two high fidelity computational fluid dynamics (CFD) tools. The computer codes utilized Large Eddy Simulation and Detached Eddy Simulation numerical approaches to accurately capture the turbulent wake of the entry vehicle and its coupling to the parachute bow-shock. The second phase was the development of fluid structure interaction (FSI) computational tools to predict parachute response to the supersonic flow field. The FSI development included the integration of the CFD from the first phase with a finite element structural model of the parachute membrane and cable elements. In this phase, a 4% of full-scale supersonic flexible parachute test program was conducted to provide validation data to the FSI code and an empirical dataset of the MSL parachute in a flight-like environment. The final phase is FSI simulations of the full-scale MSL parachute in a Mars type deployment. Findings from this program will be presented in terms of code development and validation, empirical findings from the supersonic testing, and drag performance during supersonic operation.

EDL↗

Using NASA's Worldview to Convey Scientific Finding

NASA Worldview is an interactive interface for browsing full-resolution, global satellite imagery. The application can show single or multiple layers of satellite imagery with over 700 layers available. Each layer has options such as opacity and color palettes which can be adjusted to differentiate layers or underlying data values. The timeline feature allows end-users to study historical events: changes over time can be visualized using the animation tool and exported to animated GIFs. Users can even compare two separate days using the A|B comparison feature. Every time the state of the application changes, it is saved in the URL making it easy to share findings with others.The application is accessible online for anyone to use at any time and the source code is available on GitHub.com. The Worldview source code was designed to be customizable allowing end users to turn on/off features and brand the application for their specific use case. Worldview has code contributors and end-users from all over the world who use the official tool and create personal instances to test and convey their own data.From a team of scientists studying weather over the Philippines, to a group in France studying high environmental risks, Worldview's features and portability allows end-users all over the World to gain valuable earth science insights in a multitude of ways. This presentation will emphasis how end-users are using Worldview to convey their findings.

Rice, Zachary↗

Finding Evidence of a Prebiotic Pyruvate Reaction Network in Meteorites

The organic compounds of carbonaceous chondrites are structurally diverse products of the prolonged abiotic chemistry that occurred before and during the early stages of the solar system. They also represent the types of prebiotic compounds that may have participated in chemical evolutionary processes that gave rise to life. Pyruvic acid is a key component of primary metabolism that has recently been found in carbonaceous chondrites. Its prominence in biology has inspired us to explore its chemistry and possible role in the origin of metabolism. Our laboratory investigations have found that pyruvate (the ionized form of pyruvic acid) can serve as a single-source reactant to generate what we term a pyruvate reaction network (PRN). The core of the PRN is driven by pyruvate aldol polymerization and decay reactions. These decay reactions lead to the production of stable and unstable compounds which include mono, di, and tricarboxylic acids and a variety of keto acids. Importantly, many of these reactions apparently lead back to pyruvate, establishing a feedback process. Finding evidence of this reaction network in meteorites would establish that the chemistry of pyruvate did occur in a prebiotic environment and indeed many of the known compounds found in pyruvate reaction mixtures were detected in the Murchison and Murray meteorites. However, multiple synthetic origins, not tied to pyruvate chemistry, might also explain their meteoritic presence. Thus finding compounds unique to the PRN, such as reaction intermediates, would provide stronger evidence in support of its prebiotic relevance. The identity of these intermediates can only be con-firmed by acquiring chemical standards, however, as most are not available commercially, we engaged in extensive chemical synthesis. Obtaining these standards also provides the opportunity to study their subsequent chemistry and roles in the PRN.

Rios, A. C.↗

Finding Evidence of a Prebiotic Pyruvate Reaction Network in Meteorites

The organic compounds of carbonaceous chondrites are structurally diverse products of the prolonged abiotic chemistry that occurred before and during the early stages of the solar system. They also represent the types of prebiotic compounds that may have participated in chemical evolutionary processes that gave rise to life. Pyruvic acid is a key component of primary metabolism that has recently been found in carbonaceous chondrites. Its prominence in biology has inspired us to explore its chemistry and possible role in the origin of metabolism. Our laboratory investigations have found that pyruvate (the ionized form of pyruvic acid) can serve as a single-source reactant to generate what we term a pyruvate reaction network (PRN). The core of the PRN is driven by pyruvate aldol polymerization and decay reactions. These decay reactions lead to the production of stable and unstable compounds which include mono, di, and tricarboxylic acids and a variety of keto acids. Importantly, many of these reactions apparently lead back to pyruvate, establishing a feedback process. Finding evidence of this reaction network in meteorites would establish that the chemistry of pyruvate did occur in a prebiotic environment and indeed many of the known compounds found in pyruvate reaction mixtures were detected in the Murchison and Murray meteorites. However, multiple synthetic origins, not tied to pyruvate chemistry, might also explain their meteoritic presence. Thus finding compounds unique to the PRN, such as reaction intermediates, would provide stronger evidence in support of its prebiotic relevance. The identity of these intermediates can only be confirmed by acquiring chemical standards, however, as most are not available commercially, we engaged in extensive chemical synthesis. Obtaining these standards also provides the opportunity to study their subsequent chemistry and roles in the PRN.

Rios, Andro↗

Benefits and Challenges of Model-based Software Engineering: Lessons Learned based on Qualitative and Quantitative Findings

Even though Model-based Software Engineering (MBSwE) techniques and Autogenerated Code (AGC) have been increasingly used to produce complex software systems, there is only anecdotal knowledge about the state-of-thepractice. Furthermore, there is a lack of empirical studies that explore the potential quality improvements due to the use of these techniques. This paper presents in-depth qualitative findings about development and Software Assurance (SWA) practices and detailed quantitative analysis of software bug reports of a NASA mission that used MBSwE and AGC. The mission’s flight software is a combination of handwritten code and AGC developed by two different approaches: one based on state chart models (AGC-M) and another on specification dictionaries (AGC-D). The empirical analysis of fault proneness is based on 380 closed bug reports created by software developers. Our main findings include: (1) MBSwE and AGC provide some benefits, but also impose challenges. (2) SWA done only at a model level is not sufficient. AGC code should also be tested and the models and AGC should always be kept in-sync. AGC must not be changed manually. (3) Fixes made to address an individual bug report were spread both across multiple modules and across multiple files. On average, for each bug report 1.4 modules, that is, 3.4 files were fixed. (4) Most bug reports led to changes in more than one type of file. The majority of changes to auto-generated source code files were made in conjunction to changes in either file with state chart models or XML files derived from dictionaries. (5) For newly developed files, AGC-M and handwritten code were of similar quality, while AGC-D files were the least fault prone.

Goseva-Popstojanova, Katerina↗

Surveillance for Jugular Venous Thrombosis in Long-Duration Space Flight: Findings From Twenty-Eight U.S. Astronauts

BACKGROUND: Given the high incidence of internal jugular vein (IJV) flow anomalies aboard the International Space Station and a case of thrombosis, the National Aeronautics and Space Administration (NASA) instituted an occupational surveillance program to evaluate astronauts for venous thromboembolism (VTE). Current findings of the program are presented. METHODS: NASA astronauts undergo pre- and in-flight VTE surveillance examinations using a standardized vascular ultrasound protocol, which includes evaluation for bilateral IJV compressibility, filling, flow, and spontaneous echo contrast (SEC). RESULTS: Twenty-eight NASA astronauts had terrestrial baseline examinations and at least one in-flight imaging session. The reduction of in-flight peak IJV flow speeds was significant and more pronounced on the left. Comparing the first in-flight measurement to the terrestrial baseline, peak flow speeds were reduced from 90.1±41.9 cm/s (average ±SD) to 62.1±31.6 cm/s on the right and from 76.9±41.8 cm/s to 26.8±18.2 cm/s on the left. Seven astronauts showed stagnant or retrograde flow in the left IJV. Fourteen developed appreciable SEC in the left IJV (7 greater than mild); none developed significant right-sided SEC. All IJVs were fully compressible and free from thrombi. DISCUSSION: Bilateral IJV flow speed reduction is observed in microgravity, possibly due to the multitude of available flow redistribution paths for cranial drainage. In a subset of astronauts, significant flow anomalies develop that may facilitate thrombus formation through changes in blood viscosity and speed, especially if combined with other thrombogenic factors. These findings warrant attention to the interplay between individual vascular configurations and the dynamic properties of blood as a non-Newtonian fluid in the reduced-shear flow environment of microgravity.

Ashot Sargsyan↗

Finding a contaminant source in a volume of flowing fluid

A method includes: mapping a boundary of a volume of flowing fluid; partitioning the volume by a computational mesh; finding a contaminant location at a first sensor that is disposed within the volume; obtaining a measured velocity of the flowing fluid within the volume; generating a reversed velocity vector field within the mesh, in response to the measured velocity; time stepping the contaminant location from the first sensor along the reversed velocity vector field until the contaminant location intersects the boundary of the volume; and finding a contaminant source at the intersection of the time stepped contaminant location with the boundary of the volume.

Lopez-Marrero, Vanessa↗

A new track finding algorithm based on a multi-dimensional extension of the Hough Transform

We introduce a new pattern recognition algorithm for track finding in High Energy Physics Experiments based on an extension of the Hough Transform to multiple dimensions. A remarkable property of this algorithm is that the execution time is simply proportional to the total number of the hits to be processed, making it particularly attractive for high occupancy situations. The algorithm needs to be trained using a sufficiently large set of simulated tracks. The same track finding algorithm can be used for very different detector geometries and only the set of simulated tracks used for training needs to be changed. The particular structure of the algorithm also lends itself naturally to parallel hardware implementations which, combined with its intrinsic flexibility, should provide a most powerful tool for triggering at future colliders.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Finding Real Uncertainties From Physical Simulations

Modeling strong gravitational lenses is computationally expensive for the complex data from modern and next-generation cosmic surveys. Deep learning has emerged as a promising approach for finding lenses and predicting lensing parameters, such as the Einstein radius. Mean-variance Estimators (MVEs) are a common approach for obtaining aleatoric (data) uncertainties from a neural network prediction. However, neural networks have not been demonstrated to perform well on out-of-domain target data successfully - e.g., when trained on simulated data and applied to real, observational data. In this work, we perform the first study of the efficacy of MVEs in combination with unsupervised domain adaptation (UDA) on strong lensing data. The source domain data is noiseless, and the target domain data has noise mimicking modern cosmology surveys. We find that adding UDA to MVE increases the accuracy on the target data by a factor of about two over an MVE model without UDA. Including UDA also permits much more well-calibrated aleatoric uncertainty predictions. Advancements in this approach may enable future applications of MVE models to real observational data.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Finding of Adverse Effect and Mitigation Documentation for the Stormwater Drainage and Street Systems, Substation Foundations, and the Bus Parking Lot in Mercury, Area 23, Nevada National Security Site, Nye County, Nevada

The U.S. Department of Energy, National Nuclear Security Administration Nevada Field Office (NNSA/NFO) proposes to grade the block on the southeast corner of Mercury Highway and Ranger Avenue and demolish an adjacent street segment in the town of Mercury at the Nevada National Security Site (NNSS) in Nye County, Nevada. The purpose of this letter report is to submit documentation related to the finding of effect for the undertaking and mitigation of four resources on and adjacent to the block that will be affected by planned activities to modernize parking and infrastructure in central Mercury. Two of these resources are portions of the street system and the stormwater drainage system, which are elements of the town’s infrastructure. The foundations of an old electrical substation and the bus parking lot will also be replaced by new parking or landscaping. This submission is intended to comply with the stipulations in the Programmatic Agreement between the National Nuclear Security Administration Nevada Field Office and the Nevada State Historic Preservation Officer Regarding Modernization and Operational Maintenance of the Nevada National Security Site, at Mercury in Nye County, Nevada, hereafter referred to as the Mercury PA. The town of Mercury and the immediate surrounding area have been designated the Mercury Historic District (SHPO Resource #D230), which is a property eligible to the National Register of Historic Places under Criteria A and C for its importance in supporting nuclear testing and scientific research from 1951 through 1992. During the initial architectural survey (Reno et al. 2018), all four resources were identified as contributing to the eligibility of the district.

54 ENVIRONMENTAL SCIENCES↗

Report Series: Finding of Effect and Mitigation Documentation for Building 23-W10, Mercury, Area 23, Nevada National Security Site, Nye County, Nevada

Finding of Effect: The U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Field Office (NNSA/NFO) plans to demolish Building 23-W10 in Mercury (Nevada State Historic Preservation Office [SHPO] Resource No. B15228), which is on the Nevada National Security Site (NNSS) in Nye County, Nevada (Figure 1). The purpose of the undertaking is related to the modernization of Mercury for future mission needs. The NNSA/NFO will implement this undertaking in accordance with the Programmatic Agreement between the National Nuclear Security Administration Nevada Field Office and the Nevada State Historic Preservation Officer Regarding Modernization and Operational Maintenance of the Nevada National Security Site, at Mercury in Nye County, Nevada, hereafter referred to as the Mercury PA. Building 23-W10, a supply warehouse, was installed in Mercury in 1962 (NNSS GIS Database) and served as a support facility for nuclear testing throughout much of the Cold War. It was likely produced during World War II (WWII) and previously installed at Camp Desert Rock. The town of Mercury and the immediate surrounding area have been formally determined eligible for listing in the National Register of Historic Places (National Register, NRHP) as the Mercury Historic District (MHD, SHPO Resource #D230) under Criteria A and C for their importance in supporting nuclear testing and scientific research from 1951 through 1992. Building 23-W10 was identified as a contributing element to the MHD in a 2018 architectural survey of the district (Reno et al. 2018) and recorded on a Nevada Architectural Resource Assessment (ARA) form (Reno et al. 2017). Building 23-W10 was also identified in Appendix C of the Mercury PA as a Category II contributing element. Category II properties are those that have several representatives in the MHD, such as warehouses, but may possess different engineering or architectural characteristics that distinguish them from other classes of similar elements. Building 23-W10 is a historic property for the purposes of compliance with Section 106 of the National Historic Preservation Act (NHPA) and subject to the stipulations of the Mercury PA. Mitigation: The purpose of this letter report is to support the mitigation of the demolition of Building 23-W10 (Nevada State Historic Preservation Office [SHPO] Resource No. B15228) in the Mercury Historic District (MHD, SHPO Resource #D230) at the Nevada National Security Site (NNSS) in Nye County, Nevada. The warehouse is considered contributing to the significance of the district both for its historic importance in relation to nuclear testing under Criterion A and as a part of the distinctive design and construction of the district under Criterion C. This submission is intended to comply with the stipulations in the Programmatic Agreement between the National Nuclear Security Administration Nevada Field Office and the Nevada State Historic Preservation Officer Regarding Modernization and Operational Maintenance of the Nevada National Security Site, at Mercury in Nye County, Nevada, hereafter referred to as the Mercury PA.

54 ENVIRONMENTAL SCIENCES↗

Report Series: Finding of Effect and Mitigation Documentation for Building 23-153, Mercury, Area 23, Nevada National Security Site, Nye County, Nevada

Finding of Effect: The U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Field Office (NNSA/NFO) plans to demolish Building 23-153, the Mechanical Calibration Laboratory (Calibration Lab), in Mercury (Nevada State Historic Preservation Office [SHPO] Resource No. B15271), which is on the Nevada National Security Site (NNSS) in Nye County, Nevada. The purpose of the undertaking is related to the modernization of Mercury for future mission needs. The NNSA/NFO will implement this undertaking in accordance with the Programmatic Agreement between the National Nuclear Security Administration Nevada Field Office and the Nevada State Historic Preservation Officer Regarding Modernization and Operational Maintenance of the Nevada National Security Site, at Mercury in Nye County, Nevada, hereafter referred to as the Mercury PA. Building 23-153 was constructed in Mercury in 1982 as the Mechanical Calibration Laboratory and served as a support facility for nuclear testing throughout the last decade of the Cold War. The town of Mercury and the immediate surrounding area have been formally determined eligible for listing in the National Register of Historic Places (NRHP) as the Mercury Historic District (MHD, SHPO Resource No. D230) under Criteria A and C for their importance in supporting nuclear testing and scientific research from 1951 through 1992. Building 23-153 was identified as a contributing element to the MHD in a 2018 architectural survey of the district (Reno et al. 2018) and recorded on a Nevada Architectural Resource Assessment (ARA) form (Reno et al. 2017). Building 23-153 was also identified in Appendix C of the Mercury PA as a Category II contributing element. Category II properties are those that have several representatives in the MHD but may possess different engineering or architectural characteristics that distinguish them from other classes of similar elements. Building 23-153 is a historic property for the purposes of compliance with Section 106 of the National Historic Preservation Act (NHPA) and subject to the stipulations of the Mercury PA. Mitigation: The purpose of this letter report is to submit documentation related to the mitigation of the demolition of Building 23-153, the Mechanical Calibration Laboratory (Calibration Lab, Nevada State Historic Preservation Office [SHPO] Resource No. B15271), in the Mercury Historic District (MHD, SHPO Resource No. D230) at the Nevada National Security Site (NNSS) in Nye County, Nevada. The Calibration Lab is considered contributing to the significance of the district both for its historic importance in relation to nuclear testing under Criterion A and as a part of the distinctive design and construction of the district under Criterion C. This submission is intended to comply with the stipulations in the Programmatic Agreement between the National Nuclear Security Administration Nevada Field Office and the Nevada State Historic Preservation Officer Regarding Modernization and Operational Maintenance of the Nevada National Security Site, at Mercury in Nye County, Nevada, hereafter referred to as the Mercury PA.

54 ENVIRONMENTAL SCIENCES↗

Finding of No Adverse Effect for the Façade Alteration of Building 23-117, Administration Building, Mercury, Area 23, Nevada National Security Site, Nye County, Nevada

The U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Field Office (NNSA/NFO) plans to update the façade of Building 23-117 in the town of Mercury (Nevada State Historic Preservation Office [SHPO] Resource No. B15256), which is on the Nevada National Security Site (NNSS) in Nye County, Nevada. The purpose of the undertaking is to incorporate Building 23-117 into the new Mercury campus in accordance with the master plan for the modernization of Mercury. The NNSA/NFO will implement this undertaking in accordance with the Programmatic Agreement between the National Nuclear Security Administration Nevada Field Office and the Nevada State Historic Preservation Officer Regarding Modernization and Operational Maintenance of the Nevada National Security Site, at Mercury in Nye County, Nevada, hereafter referred to as the Mercury PA. Building 23-117 was built in 1982 as the architect-engineer Administration Building1 for Holmes & Narver, a government contractor who helped design and engineer the town of Mercury and other areas on the NNSS from its inception until the termination of their contract in 1990. The building continued to be used by subsequent government contractors and is currently still in use by MSTS. The town of Mercury and the immediate surrounding area have been formally determined eligible for listing in the National Register of Historic Places (National Register, NRHP) as the Mercury Historic District (MHD, SHPO Resource No. D230) under Criteria A and C for its importance in supporting nuclear testing and scientific research from 1951 through 1992. Building 23-117 was identified as a contributing element to the MHD in a 2018 architectural survey of the district (Reno et al.) and recorded on a Nevada Architectural Resource Assessment (ARA) form (Reno et al. 2017). It is a historic property for the purposes of compliance with Section 106 of the National Historic Preservation Act (NHPA) and is subject to the stipulations of the Mercury PA. The NNSA/NFO requested that Desert Research Institute (DRI), cultural resource subject matter experts, analyze the effects of the proposed project on historic properties in the Area of Potential Effect (APE) and make a recommended finding for the undertaking in accordance with Section 106 of the NHPA and the Mercury PA. The purpose of this letter report is to submit documentation related to the mitigation of the façade alteration of Building 23-117 (Nevada State Historic Preservation Office [SHPO] Resource No. B15256) in the Mercury Historic District (MHD, SHPO Resource No. D230). This submission is intended to comply with the stipulations in the Programmatic Agreement between the National Nuclear Security Administration Nevada Field Office and the Nevada State Historic Preservation Officer Regarding Modernization and Operational Maintenance of the Nevada National Security Site at Mercury in Nye County, Nevada, hereafter referred to as the Mercury PA.

54 ENVIRONMENTAL SCIENCES↗

A Survey Protocol to Assess Meaningfulness and Usefulness of Automated Topic Finding in the NASA Aviation Safety Reporting System

Context: The NASA Aviation Safety Reporting System (ASRS) is a voluntary confidential aviation safety reporting system. The ASRS receives reports from pilots, air traffic controllers, flight attendants and other involved in aviation operations. The reports are de-identified and coded by ASRS expert safety analysts and a short descriptive synopsis is written to describe the safety issue. The de-identified reports are then disseminated to the aviation community in a number of ways including entry into an online database, Safety Alert Bulletins and For Your Information Notices, and the CALLBACK newsletter. Key to these publications are the timely processing (de-identification, coding and summarization) of new reports, which is currently done by ASRS expert safety analysts. Thus, we believe topic modelling could decrease effort in ASRS, if topics are comprehensible. Aim: We propose a methodology to evaluate whether automated topic finding using topic modelling provides meaningful and useful topics. Method: We extend the total error survey methodology to evaluate user topic comprehension of machine learning outputs. To accomplish this we performed a literature review to identify existing methods and define a construct for topic comprehension, utilizing existing ASRS synopsis writing practices to more precisely define meaningfulness and usefulness. Results: A survey protocol was created that addresses the limitations of other survey protocols found in the literature review, which we found lacking in rationale and clear protocol definition. Conclusion: The surveying of user understanding in machine learning outputs presents challenges due to the explosion of parameters to control for and the lack of systematic approach presented in the literature. More reproducible work and survey protocols are needed in the literature and our work is one step towards that direction.

topic finding↗

COVID ‐19 outcomes in patients with cancer: Findings from the University of California health system database

Abstract Background The interaction between cancer diagnoses and COVID‐19 infection and outcomes is unclear. We leveraged a state‐wide, multi‐institutional database to assess cancer‐related risk factors for poor COVID‐19 outcomes. Methods We conducted a retrospective cohort study using the University of California Health COVID Research Dataset, which includes electronic health data of patients tested for severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) at 17 California medical centers. We identified adults tested for SARS‐CoV‐2 from 2/1/2020–12/31/2020 and selected a cohort of patients with cancer. We obtained demographic, clinical, cancer type, and antineoplastic therapy data. The primary outcome was hospitalization within 30d after the first positive SARS‐CoV‐2 test. Secondary outcomes were SARS‐CoV‐2 positivity and severe COVID‐19 (intensive care, mechanical ventilation, or death within 30d after the first positive test). We used multivariable logistic regression to identify cancer‐related factors associated with outcomes. Results We identified 409,462 patients undergoing SARS‐CoV‐2 testing. Of 49,918 patients with cancer, 1781 (3.6%) tested positive. Patients with cancer were less likely to test positive (RR 0.70, 95% CI: 0.67–0.74, p < 0.001). Among the 1781 SARS‐CoV‐2‐positive patients with cancer, BCR/ABL‐negative myeloproliferative neoplasms (RR 2.15, 95% CI: 1.25–3.41, p = 0.007), venetoclax (RR 2.96, 95% CI: 1.14–5.66, p = 0.028), and methotrexate (RR 2.72, 95% CI: 1.10–5.19, p = 0.032) were associated with greater hospitalization risk. Cancer and therapy types were not associated with severe COVID‐19. Conclusions In this large, diverse cohort, cancer was associated with a decreased risk of SARS‐CoV‐2 positivity. Patients with BCR/ABL‐negative myeloproliferative neoplasm or receiving methotrexate or venetoclax may be at increased risk of hospitalization following SARS‐CoV‐2 infection. Mechanistic and comparative studies are needed to validate findings.

60 APPLIED LIFE SCIENCES↗

Finding Hidden Patterns in High Resolution Wind Flow Model Simulations

Wind flow data is critical in terms of investment decisions and policy making. High resolution data from wind flow model simulations serve as a supplement to the limited resource of original wind flow data collection. Given the large size of data, finding hidden patterns in wind flow model simulations are critical for reducing the dimensionality of the analysis. In this work, we first perform dimension reduction with two autoencoder models: the CNN-based autoencoder (CNN-AE) [1], and hierarchical autoencoder (HIER-AE) [2], and compare their performance with the Principal Component Analysis (PCA). We then investigate the super-resolution of the wind flow data. By training a Generative Adversarial Network (GAN) with 300 epochs, we obtained a trained model with 2× resolution enhancement. We compare the results of GAN with Convolutional Neural Network (CNN), and GAN results show finer structure as expected in the data field images. Also, the kinetic energy spectra comparisons show that GAN outperforms CNN in terms of reproducing the physical properties for high wavenumbers and is critical for analysis where high-wavenumber kinetics play an important role.

97 MATHEMATICS AND COMPUTING↗