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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 91 records · Page 5

Performance of OVERFLOW-D Applications based on Hybrid and MPI Paradigms on IBM Power4 System

This report briefly discusses our preliminary performance experiments with parallel versions of OVERFLOW-D applications. These applications are based on MPI and hybrid paradigms on the IBM Power4 system here at the NAS Division. This work is part of an effort to determine the suitability of the system and its parallel libraries (MPI/OpenMP) for specific scientific computing objectives.

Djomehri, M. Jahed↗

Macromolecular Expression and Function: A New Paradigm for NASA Risk Assessment

Predicting risks in humans of either acute effects such as bone loss or muscle wasting, or late effects such as cancer, is challenging. To an approximation, this is because uncertainties of exposure to stress factors or toxic agents and the uniformity of processing subsequent damage at the cellular level within a complex set of biological variables degrade the confidence of predicting pathologic outcome. A cellular biodosimeter that simultaneously reports 1) the type of damage due to that exposure, 2) the quantity of damage incurred by that exposure, and 3) the dataset used to assess risk of developing pathologic outcome caused by that exposure would therefore be useful for predicting ultimate risks faced by an individual, such as an astronaut. It is suggested that such a biodosimeter can be based upon analyses of gene-expression and protein expression whereby large datasets of cellular response to damage are obtained and analyzed for expression-profiles correlated with established end points and molecular markers predictive for risks being assessed. The usefulness of multiparametric cellular biodosimeters could be realized by quantitatively profiling these datasets using techniques of bioinformatics. Such an approach contributes to the foundation of molecular epidemiology as a new scientific discipline, and represents a new paradigm of risk assessment.

Richmond, Robert↗

Differences in the hemodynamic response to event-related motor and visual paradigms as measured by near-infrared spectroscopy

Several current brain imaging techniques rest on the assumption of a tight coupling between neural activity and hemodynamic response. The nature of this neurovascular coupling, however, is not completely understood. There is some evidence for a decoupling of these processes at the onset of neural activity, which manifests itself as a momentary increase in the relative concentration of deoxyhemoglobin (HbR). The existence of this early component of the hemodynamic response function, however, is controversial, as it is inconsistently found. Near infrared spectroscopy (NIRS) allows quantification of levels of oxyhemoglobin (HbO(2)) and HbR during task performance in humans. We acquired NIRS data during performance of simple motor and visual tasks, using rapid-presentation event-related paradigms. Our results demonstrate that rapid, event-related NIRS can provide robust estimates of the hemodynamic response without artifacts due to low-frequency signal components, unlike data from blocked designs. In both the motor and visual data the onset of the increase in HbO(2) occurs before HbR decreases, and there is a poststimulus undershoot. Our results also show that total blood volume (HbT) drops before HbO(2) and undershoots baseline, raising a new issue for neurovascular models. We did not find early deoxygenation in the motor data using physiologically plausible values for the differential pathlength factor, but did find one in the visual data. We suggest that this difference, which is consistent with functional magnetic resonance imaging (fMRI) data, may be attributable to different capillary transit times in these cortices.

NASA Program Biomedical Research and Countermeasur↗

Task switching and response correspondence in the psychological refractory period paradigm

Three experiments examined the effects of task switching and response correspondence in a psychological refractory period paradigm. A letter task (vowel-consonant) and a digit task (odd-even) were combined to form 4 possible dual-task pairs in each trial: letter-letter, letter-digit, digit-digit, and digit-letter. Foreknowledge of task transition (repeat or switch) and task identity (letter or digit) was varied across experiments: no foreknowledge in Experiment 1, partial foreknowledge (task transition only) in Experiment 2, and full foreknowledge in Experiment 3. For all experiments, the switch cost for Task 2 was additive with stimulus onset asynchrony, and the response-correspondence effect for Task 2 was numerically smaller in the switch condition than in the repeat condition. These outcomes suggest that reconfiguration for Task 2 takes place after the central processing of Task 1 and that the crosstalk correspondence effect is due to response activation by way of stimulus-response associations.

Cognition↗

The footprints of visual attention in the Posner cueing paradigm revealed by classification images

In the Posner cueing paradigm, observers' performance in detecting a target is typically better in trials in which the target is present at the cued location than in trials in which the target appears at the uncued location. This effect can be explained in terms of a Bayesian observer where visual attention simply weights the information differently at the cued (attended) and uncued (unattended) locations without a change in the quality of processing at each location. Alternatively, it could also be explained in terms of visual attention changing the shape of the perceptual filter at the cued location. In this study, we use the classification image technique to compare the human perceptual filters at the cued and uncued locations in a contrast discrimination task. We did not find statistically significant differences between the shapes of the inferred perceptual filters across the two locations, nor did the observed differences account for the measured cueing effects in human observers. Instead, we found a difference in the magnitude of the classification images, supporting the idea that visual attention changes the weighting of information at the cued and uncued location, but does not change the quality of processing at each individual location.

Non-NASA Center↗

Genomic instability and bystander effects: a paradigm shift in radiation biology?

A basic paradigm in radiobiology is that, following exposure to ionizing radiation, the deposition of energy in the cell nucleus and the resulting damage to DNA, the principal target, are responsible for the radiation's deleterious biological effects. Findings in two rapidly expanding fields of research--radiation-induced genomic instability and bystander effects--have caused us to reevaluate these central tenets. In this article, the potential influence of induced genomic instability and bystander effects on cellular injury after exposure to low-level radiation will be reviewed.

NASA Discipline Radiation Health↗

Resolving Risks in Individual Astronauts: A New Paradigm for Critical Path Exposures

The limited number of astronauts available for risk-assessment prevents classic epidemiologic study, and thereby requires alternative approach to assessing risks within individual astronauts exposed to toxic agents identified within the Bioastronautics Critical Path Roadmap (BCPR). Developing a system of noninvasive real-time biodosimetry that provides large datasets for analyses before, during, and after missions for simultaneously determining 1) the kinds of toxic insult, 2) the degree of that insult, both within tissues absorbing that insult, would be usehl for resolving statistically significant risk-assessment in individual astronauts. Therefore, a currently achievable multiparametric paradigm is presented for use in analyzing gene-expression and protein-expression so as to establish predictive outcomes.

Richmond, Robert C.↗

Risk as a Resource - A New Paradigm

NASA must change dramatically because of the current United States federal budget climate. The American people and their elected officials have mandated a smaller, more efficient and effective government. For the past decade, NASA's budget had grown at or slightly above the rate of inflation. In that era, taking all steps to avoid the risk of failure was the rule. Spacecraft development was characterized by extensive analyses, numerous reviews, and multiple conservative tests. This methodology was consistent with the long available schedules for developing hardware and software for very large, billion dollar spacecraft. Those days are over. The time when every identifiable step was taken to avoid risk is being replaced by a new paradigm which manages risk in much the same way as other resources (schedule, performance, or dollars) are managed. While success is paramount to survival, it can no longer be bought with a large growing NASA budget.

Risk Resource↗

A New Paradigm for Gamma Ray Bursts: Long Term Accretion Rate Modulation by an External Accretion Disk

We present a new way of looking at the very long term evolution of GRBs in which the disk of material surrounding the putative black hole powering the GRB jet modulates the mass flow, and hence the efficacy of the process that extracts rotational energy from the black hole and inner accretion disk. The pre-Swift paradigm of achromatic, shallow-to-steep "breaks" in the long term GRB light curves has not been borne out by detailed Swift data amassed in the past several years. We argue that, given the initial existence of a fall-back disk near the progenitor, an unavoidable consequence will be the formation of an "external disk" whose outer edge continually moves to larger radii due to angular momentum transport and lack of a confining torque. The mass reservoir at large radii moves outward with time and gives a natural power law decay to the GRB light curves. In this model, the different canonical power law decay segments in the GRB identified by Zhang et al. and Nousek et al. represent different physical states of the accretion disk. We identify a physical disk state with each power law segment.

Cannizzo, John↗

Shifting the Inertial Navigation Paradigm with MEMS Technology

Why don t you use MEMS? is one of the most common questions posed to navigation systems engineers designing inertial navigation solutions in the modern era. The question stems from a general understanding that great strides have been made in terrestrial MEMS accelerometers and attitude rate sensors in terms of accuracy, mass, and power. Yet, when compared on a unit-to-unit basis, MEMS devices do not provide comparable performance (accuracy) to navigation grade sensors. This paper will propose a paradigm shift where the comparison in performance is between multiple MEMS devices and a single navigation grade sensor. The concept is that systematically, a sufficient number of MEMS sensors may mathematically provide comparable performance to a single navigation grade device and be competitive in terms power and mass allocations when viewed on a systems level. The implication is that both inertial navigation system design and fault detection, identification, and recovery could benefit from a system of MEMS devices in the same way that swarm sensing has benefited Earth observation and astronomy. A survey of the state of the art in inertial sensor accuracy scaled by mass and power will be provided to show the specific error in MEMS and navigation graded devices, a mathematical comparison of multi-unit to single-unit sensor errors will be developed, and preliminary applications to Constellation vehicles will be explored.

Crain, Timothy↗

Shifting the Intertial Navigation Paradigm with the MEMS Technology

"Why don't you use MEMS?" is of the most common questions posed to navigation systems engineers designing inertial navigation solutions in the modern era. The question stems from a general understanding that great strides have been made in terrestrial MEMS accelerometers and attitude rate sensors in terms of accuracy, mass, and power. Yet, when compared on a unit-to-unit basis, MEMS devices do not provide comparable performance (accuracy) to navigation grade sensors in several key metrics. This paper will propose a paradigm shift where the comparison in performance is between multiple MEMS devices and a single navigation grade sensor. The concept is that systematically, a sufficient number of MEMS sensors may mathematically provide comparable performance to a single navigation grade device and be competitive in terms power and mass allocations when viewed on a systems level. The implication is that both inertial navigation system design and fault detection, identification, and recovery could benefit from a system of MEMS devices in the same way that swarm sensing has benefited Earth observation and astronomy. A survey of the state of the art in inertial sensor accuracy scaled by mass and power will be provided to show the scaled error in MEMS and navigation graded devices, a mathematical comparison of multi-unit to single-unit sensor errors will be developed, and preliminary application to an Orion lunar skip atmospheric entry trajectory will be explored.

Crain, Timothy P., II↗

Changing the Safety and Mission Assurance (S and MA) Paradigm

This slide presentation reviews the change in the work and impact of the Safety and Mission Assurance directorate at Marshall Space Flight Center. It reviews the background and the reasons given for a strong Safety & Mission Assurance presence in all planning for space flight. This was pointed out by the Rogers Commission Report after the Space Challenger accident, by the Columbia Accident Investigation Board (CAIB) and by a 2006 NASA Exploration Safety Study (NESS) Team. The overall objective of the work in this area was to improve and maintain S&MA expertise and skills. Training for this work was improved and the S&MA organization was reorganized. This has resulted in a paradigm shift for NASA's safety efforts, which is described. The presentation then reviews the impact of the new S&MA work in the Ares I design and development.

Malone, Roy W.↗

Rapid Turn Around BRIC-PDFU Payload: A New Paradigm for Spaceflight Experiments

In 2009, NASA's Fundamental Space Biology program provided an opportunity for investigators to propose for a quick-turn-around multi-user spaceflight experiment that focused on the model plant species Arabidopsis thaliana. This was a passive payload with no on-orbit power or communications available. An NRA was rapidly written (8/09), released (NNH09ZTT004N; 9/09), proposals were received (11/09) and peer reviewed with 3 PI groups selected for flight (1/10): (1) A-L Paul, University of Florida, (2) E. Blancaflor, Noble Foundation, (3) J. Kiss, Miami University. The investigators flew Arabidopsis seeds or callus cultures of their choosing (plated onto 60 mm diameter Petri dishes containing agarsolidified media) on the STS-131 Space Shuttle mission (launched 4/5/10) and the resulting plant tissues returned to earth on 4/20/10. Each petri dish was placed inside its own Petri Dish Fixation Unit (PDFU), which was assembled and loaded with either formaldehyde, glutaraldehyde or RNAlater for crew-facilitated on-orbit fixation. Five PDFUs plus a temperature data logger were loaded into each of 8 BRIC-PDFUs (Biological Research In Canisters PDFU). All eight BRIC-PDFUs were loaded into a half tray along with actuator equipment that the crew used for the fixations. Pre-flight turn-over was 28 hours prior to launch. The BRIC-PDFU assemblies were removed from the orbiter and handed over to the investigator teams for processing 5-6 hours after landing. This payload demonstrated a rapid response turnaround for flying multiple peer-reviewed science investigations using previously flown hardware and minimal ISS-resources. The approach used reduced both hardware/certification and PI costs. The time waiting for a flight opportunity for the selected Pls was minimal. This new paradigm for spaceflight experiments may provide a model for future flight research opportunities. The ultimate goal is to fly as many investigators as rapidly as possible and reinvigorate the space biology community while obtaining high-quality, peer-reviewed science.

Levine, Howard G.↗

TAMU: Blueprint for A New Space Mission Operations System Paradigm

The Transferable, Adaptable, Modular and Upgradeable (TAMU) Flight Production Process (FPP) is a System of System (SOS) framework which cuts across multiple organizations and their associated facilities, that are, in the most general case, in geographically disperse locations, to develop the architecture and associated workflow processes of products for a broad range of flight projects. Further, TAMU FPP provides for the automatic execution and re-planning of the workflow processes as they become operational. This paper provides the blueprint for the TAMU FPP paradigm. This blueprint presents a complete, coherent technique, process and tool set that results in an infrastructure that can be used for full lifecycle design and decision making during the flight production process. Based on the many years of experience with the Space Shuttle Program (SSP) and the International Space Station (ISS), the currently cancelled Constellation Program which aimed on returning humans to the moon as a starting point, has been building a modern model-based Systems Engineering infrastructure to Re-engineer the FPP. This infrastructure uses a structured modeling and architecture development approach to optimize the system design thereby reducing the sustaining costs and increasing system efficiency, reliability, robustness and maintainability metrics. With the advent of the new vision for human space exploration, it is now necessary to further generalize this framework to take into consideration a broad range of missions and the participation of multiple organizations outside of the MOD; hence the Transferable, Adaptable, Modular and Upgradeable (TAMU) concept.

Ruszkowski, James T.↗

TAMU: A New Space Mission Operations Paradigm

The Transferable, Adaptable, Modular and Upgradeable (TAMU) Flight Production Process (FPP) is a model-centric System of System (SoS) framework which cuts across multiple organizations and their associated facilities, that are, in the most general case, in geographically diverse locations, to develop the architecture and associated workflow processes for a broad range of mission operations. Further, TAMU FPP envisions the simulation, automatic execution and re-planning of orchestrated workflow processes as they become operational. This paper provides the vision for the TAMU FPP paradigm. This includes a complete, coherent technique, process and tool set that result in an infrastructure that can be used for full lifecycle design and decision making during any flight production process. A flight production process is the process of developing all products that are necessary for flight.

Meshkat, Leila↗

Paradigms and Paradoxes: Dawn at Vesta

While confirming the popular paradigm of Vesta as the parent body of the HED meteorites, Dawn measurements have discovered many unexpected aspects of the vestan surface. First, an olivine layer was not found in the bottom of the large basin near the south pole of Vesta. In fact, while patches of olivine have been found in the north, it is rare on the surface. Secondly, while Vesta has little gravity and appears to have completely differentiated, it is not completely dry evidence for transient flows and pits resulting from devolatization have been found, implying a substantial amount of accessible water. Thirdly, transport of material to the surface of Vesta from elsewhere in the asteroid belt appears as dark material buried near the top of the crust to Vesta. This may have arrived in a single large impact and been spread around the surface and buried, later to be re-excavated. However, it is not certain that this is the only scenario possible for the source of this material. In short, Dawn's observations of Vesta have been both reassuring but unsettling at the same time.

Raymond, C. A.↗

The Deep Space Atomic Clock: Ushering in a New Paradigm for Radio Navigation and Science

The Deep Space Atomic Clock (DSAC) mission will demonstrate the on-orbit performance of a high-accuracy, high-stability miniaturized mercury ion atomic clock during a year-long experiment in Low Earth Orbit. DSAC's timing error requirement provides the frequency stability necessary to perform deep space navigation based solely on one-way radiometric tracking data. Compared to a two-way tracking paradigm, DSAC-enabled one-way tracking will benefit navigation and radio science by increasing the quantity and quality of tracking data. Additionally, DSAC also enables fully-autonomous onboard navigation useful for time-sensitive situations. The technology behind the mercury ion atomic clock and a DSAC mission overview are presented. Example deep space applications of DSAC, including navigation of a Mars orbiter and Europa flyby gravity science, highlight the benefits of DSAC-enabled one-way Doppler tracking.

atomic clock↗

LunarCubes: Application of the Cubesat Paradigm to Lunar Missions

We have evaluated the application of the CubeSat Paradigm for deep space exploration, often referred to as LunarCube. Over the course of this year, we conducted systems definition and design activities, with focus on enhanced guidance, navigation, and control as well as propulsion requirements for cislunar space operation, thermal requirements and communication as dominant drivers for long duration operation on the lunar surface. The end result is costeffective, generic design(s) for a cross-section of future high priority space or surface payloads for planetary, heliophysics, and astrophysics disciplines, the requirements for which are described.

Lunar↗