SEARCH · Search NASA

Results for “regional air mobility”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

SourceResearch connectionFrom yearThrough year

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 91 records · Page 5

All sources NASA NTRS DOE OSTI

NASA NTRS2025

Considerations for Optimal Sensor Placement for Higher Accuracy Object Localization for Urban Air Mobility

Previous research into object localization has shown that sensor placement and alignment plays an important role in achieving higher accuracy levels of the estimated location of a tracked Urban Air Mobility Vehicle. In general, a near-orthogonal intersection between the ground node observation vectors results in the highest accuracy due to a smaller overlapping uncertainty region between both. This applies to triangulation by means of ground node camera angle observations as well as trilateration by means of ground node distance measurements. However, this simple concept is not easily fulfilled with a network of a limited number of static ground nodes and a moving object to be localized. This case study performs sensitivity analyses and explores practical ways on how to achieve higher estimate accuracy levels in this context.

sensor placement↗

DOE OSTI2020

A Convergence of Public-Private Benefits in Denver: Surveys and Analyses to Inform Urban Mobility-, Energy-, Infrastructure- and Behavior-Related Innovation: Preprint

Cities, public transit agencies, and new private ride hailing services seek to understand emerging traveler dynamics, the shifting demographics of urban travelers,and new energy-efficient mobility opportunities. This includes exploring how new infrastructure investments, public and private mobility services, and smart-phone mobility apps are reshaping behaviors, demands (e.g. mobility-on-demand services), travel experiences and energy-efficient urban travel preferences. Currently, cities and metropolitan regions are providing and experimenting with many new mobility options, technologies, and personalized information services at the intersection of urban mobility, energy, and infrastructure systems (e.g., new commuter rail). To date, technology alone has not been able to crack the nut of 'creating faster trip times, less congestion, safer streets, and cleaner air for its citizens through fewer cars on the road'. This paper focuses on this gap by offering new concepts and potential for integrated approaches. Accommodating more vehicles miles traveled in cities, without increases in person miles traveled (PMT), could be costly, generating: 1) tremendous demands for new infrastructure, land, road space, materials, and energy; 2) higher traffic fatality risks; and 3) worsening air quality. Therefore, this study focuses on reducing single occupancy vehicle use by enhancing integrated mobility, helping transit and ridehailing increase occupancy in ways that also reduce energy use, and improve quality of life for urban travelers and communities. This study focuses on a survey of urban travelers in Denver, as a representative case study for metropolitan regions experiencing rapid growth, ageing populations, increased urban sprawl, traffic-related delays, and inefficient energy use per PMT.

24 POWER TRANSMISSION AND DISTRIBUTION↗

NASA NTRSDate not supplied

Wildfire Emission Transport and Its Impact on the Local Air Quality – Case Study Example from the LISTOS Campaign

The high O3 concentration and large aerosol backscatter were measured in New York City(NYC) region and Connecticut (CT) coastline between August 15-16, 2018 during the Long Island Sound Tropospheric Ozone Study (LISTOS) campaign. Two TOLNet ozone lidar systems, NASA Goddard Space Flight Center Tropospheric Ozone Differential Absorption Lidar (GSFC TROPOZ DIAL)and Langley Research Center (LaRC) Mobile Ozone Lidar (LMOL),were used to obtain vertical and temporal variation of local O3 concentration. The airborne High Altitude Lidar Observatory (HALO) system was used to detect the regional aerosol characteristic during this episode. The complex relationship between ozone and aerosol characteristics of wildfire emission layers was investigated. The HYSPLIT back-trajectory of the measured air parcel shows that the increase of the O3 concentration and aerosol backscatter are attributed to the significant wildfires in the Pacific Northwest and British Columbia regions during August 2018. Through correlation analyses, unique clustering relationships are identified between ozone and aerosol for different air mass types. This case study is further investigated in relation to satellite data from MODIS, MISR and CALIPSO to characterize plume behavior during transport. The importance of wildfire emission transport will be discussed in context of its impact to surface air quality at significant distances from fire events.

Liqiao Lei↗

NASA NTRS2022

Optimal Locations for Air Mobility Vertiports

The purpose of this study was to effectively solicit the public to obtain inputs on potential Advanced Air Mobility (AAM) vertiport locations for UAM and RAM operations that transport people, specifically: where they would like to see vertiports located, and how they would like to use this new mode of transport (e.g. for “local” trips across town, for more “regional” trips between cities/towns, for business-related purposes, for leisure/personal purposes, routinely or only for “special” occasions, etc.) Maven conducted an electronic survey of individuals residing in specific geographies in order to obtain a broadly representative sample of the citizenry across all demographics and population density designations (e.g. rural, exurban, suburban, and urban). For the purposes of this survey, Maven received input from over 1,500 individuals divided between the Los Angeles Metropolitan area (as a general proxy for urban residents), and the state of Ohio (as a general proxy for suburban, exurban, and rural residents).

Advanced air mobility↗

NASA NTRSDate not supplied

AAM NC Tech Talk: Intro to Amazon Web Services

The purpose of this Tech Talk is to engage with the Advance Air Mobility National Campaign community on the use of a cloud provider to promote public confidence and accelerate the realization of emerging aviation markets for passenger and cargo transportation in urban, suburban, rural, and regional environments.

AWS↗

NASA NTRSDate not supplied

A Simulation Architecture for Air Traffic Over Urban Environments Supporting Autonomy Research in Advanced Air Mobility

NASA is conducting investigations into Advanced Air Mobility (AAM) concepts, aircraft, and operations. One of the most challenging scenarios for AAM will be enabling safe routine access into densely populated urban centers. To address challenges in the urban environment, a moderately high-fidelity simulation capability is needed to investigate AAM flight operations over a regional area for the development and evaluation of autonomy technologies. This paper describes a system to simulate flight operations around regions such as the San Francisco-Oakland Bay area at a moderately-high scale (10's-100's of flights) that incorporates detailed vehicle models and control necessary to support research in airborne autonomy. The flight vehicle utilizes NASA AAM concept vehicle dynamics integrated with a custom flight management system and flight control system to accurately simulate all phases of flight. Glass cockpit displays have been developed for monitoring aircraft operation over a detailed simulated urban environment. Simulation models have been integrated to simulate air and ground-based sensors, such as radar and LIDAR. The commercial X-Plane software package is used as a rendering engine to mimic vision-based sensors (such as onboard and ground-based cameras) at various times of day and in various weather conditions over a relatively detailed graphical model of the city. The paper presents a detailed illustration of the simulation and software architecture used for traffic over this urban region. This system is enabling the evaluation of NASA research concepts in autonomy for urban AAM operations on the path toward aircraft flight test evaluation.

Keerthana Kannan↗

NASA NTRS2004

Application of AirCell Cellular AMPS Network and Iridium Satellite System Dual Mode Service to Air Traffic Management

The AirCell/Iridium dual mode service is evaluated for potential applications to Air Traffic Management (ATM) communication needs. The AirCell system which is largely based on the Advanced Mobile Phone System (AMPS) technology, and the Iridium FDMA/TDMA system largely based on the Global System for Mobile Communications(GSM) technology, can both provide communication relief for existing or future aeronautical communication links. Both have a potential to serve as experimental platforms for future technologies via a cost effective approach. The two systems are well established in the entire CONUS and globally hence making it feasible to utilize in all regions, for all altitudes, and all classes of aircraft. Both systems have been certified for air usage. The paper summarizes the specifications of the AirCell/Iridium system, as well as the ATM current and future links, and application specifications. the paper highlights the scenarios, applications, and conditions under which the AirCell/Iridium technology can be suited for ATM Communication.

Shamma, Mohammed A.↗

NASA NTRSDate not supplied

Simulating Secure Data Exchange and Storage for Urban Air Mobility Environments

Urban Air Mobility (UAM) defines an environment for managing operations of vertical takeoff and landing (VTOL) and short takeoff and landing (STOL) vehicles in an urban environment. Within a UAM environment, UAM operators manage fleets of vehicles, relying on Providers of Services for UAM (PSUs) for managing flights in a region of airspace. Flight plan deconfliction is primarily performed by the Discovery and Synchronization Service (DSS), and the Federal Aviation Administration (FAA) maintains control over the UAM space via the FAA-Industry Exchange Protocol (FIDXP). UAM is a federated environment with many different entities owning and operating vehicles, PSUs, and other services. These entities often need to interoperate or access data generated by other organizations. This paper demonstrates the feasibility of using blockchain to facilitate a secure data exchange and storage for this flight information in a UAM environment. In particular, this paper is focused on flight plans and telemetry data. A blockchain network was developed with a set of smart contracts for managing relevant flight data. Hyperledger Fabric was chosen as it is performent, scalable, and allows organizations to reuse existing public key infrastructure (PKI) for identity management. A set of simulated UAM services were also developed. These services propose flight plans and negotiate with other UAM services for airspace access. All interactions between UAM services, as well as vehicle telemetry data, is recorded onto the blockchain. Vehicle telemetry data is generated by a vehicle flight simulation service. This paper successfully demonstrates the feasibility of using blockchain as a secure data exchange and storage mechanism in a UAM environment.

UAM↗

DOE OSTI2024

Observed Variability in Convective Cell Characteristics and Near-Storm Environments across the Sea- and Bay-Breeze Fronts in Southeast Texas

Abstract During the DOE Atmospheric Radiation Measurement (ARM) Tracking Aerosol Convection Interactions Experiment (TRACER) IOP spanning June–September 2022, two fixed ARM sites and a mobile team concurrently sampled the airmass heterogeneity across sea- and bay-breeze fronts around the greater Houston metropolitan region. Here, we quantify the spatiotemporal variability between maritime (coastal/bay side of breeze fronts) and continental (inland side of breeze fronts) air masses over 15 IOP days characterized by strong sea-breeze forcing. We analyze environmental profile data from 177 radiosondes and use S- and C-band radar data to track and quantify the variability in attributes of more than 2300 shallow and transitioning cells across different air masses. The composite analysis of environmental profiles indicates that during the early afternoon, the sea-breeze maritime air mass exhibits lower convective available potential energy (CAPE) than the bay-breeze maritime air mass. As the sea breeze advances inland with time, CAPE within the maritime air mass exceeds that of the continental air mass to the north of the breeze fronts. In general, maritime cells have a larger mean composite reflectivity and cell widths than continental cells; however, the response varies between shallow and transitioning cells. Mean composite 20-dB Z echo-top heights, however, are similar across air masses for both shallow and transitioning cells. The continental and maritime inflow air mass for transitioning cells has significantly different mean values for mixed-layer entrainment CAPE, lifted condensation level, level of free condensation, boundary layer depth, and diluted equilibrium level. For shallow cells, only total precipitable water shows a significant difference. Significance Statement The greater Houston metropolitan area is a natural laboratory for understanding the individual impacts of background meteorology and aerosols on convective clouds. Due to its proximity to the Gulf Coast and Galveston Bay, the Houston region experiences a diurnal precipitation cycle in the summer, driven by convection triggered from sea- and bay-breeze fronts. These fronts act as a boundary between air masses with distinct thermodynamic and environmental characteristics. Convergence along these fronts and interactions between storm outflow and the fronts facilitate convection initiation in different mesoscale air masses. This study quantifies the heterogeneity among these air masses while investigating their influence on cloud microphysics. We find that the effect of airmass heterogeneity is more pronounced for the bulk microphysical properties in shallow clouds.

Sharma, Milind↗

NASA NTRS2016

Satellite-Surface Perspectives of Air Quality and Aerosol-Cloud Effects on the Environment: An Overview of 7-SEAS BASELInE

The objectives of 7-SEASBASELInE (Seven SouthEast Asian Studies Biomass-burning Aerosols and Stratocumulus Environment: Lifecycles and Interactions Experiment) campaigns in spring 2013-2015 were to synergize measurements from uniquely distributed ground-based networks (e.g., AERONET (AErosol RObotic NETwork)), MPLNET ( NASA Micro-Pulse Lidar Network)) and sophisticated platforms (e.g.,SMARTLabs (Surface-based Mobile Atmospheric Research and Testbed Laboratories), regional contributing instruments), along with satellite observations retrievals and regional atmospheric transport chemical models to establish a critically needed database, and to advance our understanding of biomass-burning aerosols and trace gases in Southeast Asia (SEA). We present a satellite-surface perspective of 7-SEASBASELInE and highlight scientific findings concerning: (1) regional meteorology of moisture fields conducive to the production and maintenance of low-level stratiform clouds over land; (2) atmospheric composition in a biomass-burning environment, particularly tracers-markers to serve as important indicators for assessing the state and evolution of atmospheric constituents; (3) applications of remote sensing to air quality and impact on radiative energetics, examining the effect of diurnal variability of boundary-layer height on aerosol loading; (4) aerosol hygroscopicity and ground-based cloud radar measurements in aerosol-cloud processes by advanced cloud ensemble models; and (5) implications of air quality, in terms of toxicity of nanoparticles and trace gases, to human health. This volume is the third 7-SEAS special issue (after Atmospheric Research, vol. 122, 2013; and Atmospheric Environment, vol. 78, 2013) and includes 27 papers published, with emphasis on air quality and aerosol-cloud effects on the environment. BASELInE observations of stratiform clouds over SEA are unique, such clouds are embedded in a heavy aerosol-laden environment and feature characteristically greater stability over land than over ocean, with minimal radar surface clutter at a high vertical spatial resolution. To facilitate an improved understanding of regional aerosol-cloud effects, we envision that future BASELInE-like measurement modeling needs fall into two categories: (1) efficient yet critical in-situ profiling of the boundary layer for validating remote-sensing retrievals and for initializing regional transport chemical and cloud ensemble models; and (2) fully utilizing the high observing frequencies of geostationary satellites for resolving the diurnal cycle of the boundary layerheight as it affects the loading of biomass-burning aerosols, air quality and radiative energetics.

AERONET↗

NASA NTRSDate not supplied

An Impedance-Based Complexity Metric for Unmanned Aircraft System Traffic Scenario Classification

This paper introduces an impedance-based metric to capture the complexity of a given unmanned aircraft system traffic scenario. The metric accounts for both the number of aircraft and the traffic flow pattern. The work presented here extends an earlier approach that introduced another scenario complexity metric based on the number of potential conflicts weighted by the conflict resolution cost associated. Complexity measurements for randomly-generated scenarios were produced through high-fidelity fast-time simulations and treated as baseline. Then the impedance based metric was evaluated, for the same scenarios, without the need for an actual flight simulation and a conflict resolution method. The results show that the impedance-based metric has a strong correlation to the baseline data and performs marginally better than the weighted conflict-based complexity metric introduced in the earlier work. The metric computation generates impedance maps which are useful for identifying high complexity regions in a scenario, where flight plan changes might be necessitated. This metric can therefore be used, in conjunction with other complexity metrics, to inform adequate traffic management strategies and classify a traffic scenario as acceptable, unacceptable or acceptable with changes made to flight plans that pass through the high complexity regions. The metric can also be used as a guidance metric for strategic conflict management methods.

Complexity↗

NASA NTRSDate not supplied

A Psychoacoustic Test on the Effect of Masking on Annoyance to Urban Air Mobility Vehicle Noise

Urban Air Mobility (UAM) vehicles have a large range of designs and configurations that lead to new noise characteristics and potentially different perceptual responses when compared to traditional aircraft. In addition, UAM vehicles are expected to operate around and within densely populated regions where the presence of ambient background noise is often present. Strategically, this can be leveraged to inform vehicle design and operations to partially or completely mask UAM noise, allowing for mitigation of negative responses and an increased number of allowed operations. A psychoacoustic test was conducted to investigate how masking effects can influence the annoyance response to a low frequency harmonic tone complex (80-320 Hz). To do this, five test subjects compared their annoyance response to the low frequency tonal noise with a higher frequency broadband noise (10dB down bandwidth between 300-2000 Hz), with and without a masking noise present. Detection thresholds were also measured for both sounds to help fit a model to the data. Although the effect of masking on annoyance is complex, results indicate that for some individuals, masking leads to a lower annoyance than the sound level alone would predict.

Matthew Boucher↗

NASA NTRS2023

Analysis of Strategic Conflict Management Approaches as Applied to Simulated UAM Operations

This report presents the results of a comparison analysis of candidate Strategic Conflict Management (SCM) strategies as applied to Urban Air Mobility (UAM) operations. The SCM strategies investigated included: no SCM, resource scheduling (RS), resource flow rates (FR), area-based flow rates (AR), and conflict detection and resolution (CR). The study evaluated each strategy against the same 3 levels of flight demand in a representative airspace construct for the Dallas/Fort Worth region. The study also accounted for different levels of uncertainty in operational planning and equivalent levels of trajectory following error. In the analysis, we compared the SCM strategies’ effectiveness in reducing the need for the tactical conflict management layer to act and looked at the metrics of unmitigated losses-of-separation (LOS), flight delays imposed by strategic planning, and throughput of the overall airspace. The study results indicated that the CR strategy was the most effective at reducing LOS and percentage of flights with LOS, even in the presence of trajectory error when uncertainty is accounted for in planning. Thus, if the objective is to reduce the number of actions that the tactical conflict management layer will have to take, in terms of conflicts that may need to be resolved, CR is the strategy to use. The FR strategy was found to be the worst at reducing LOS and percentage of flights with LOS. Thus, it is not very effective at reducing the actions required by a tactical conflict management layer. In the airspace tested, the demand was high enough to produce unacceptable levels of flight delay and reductions of throughput when the SCM strategies were implemented. This was especially evident at the higher levels of trajectory uncertainty and error. The need to account for expected levels of uncertainty becomes more and more important as the demand level increases and as the level of trajectory error increases. This is because the likelihood of flights with LOS increases as the density of operations increases and as the level of trajectory error increases. Accounting for uncertainty in the SCM strategies improves the strategy effectiveness with respect to LOS but increases delays and reduces throughput. Thus, there is a tradeoff between scalability and allowable levels of uncertainty. That is, we can implement an air traffic management construct that allows high levels of uncertainty, but we can expect that same system to have limits on scalability that may be evident even at small demand levels, such as those used in this study. Therefore, the results in this study indicate that an air traffic system should attempt to implement mechanisms appropriate for reducing uncertainty where possible in order to increase the chances for scalability. And this increased level of predictability of operations needs to be balanced with mechanisms for ensuring flexibility when operational conditions and plans need to change, even though those types of changes should be the exception rather than the rule under normal conditions. The study also introduced a trade space that could serve as a mechanism for selecting the appropriate SCM strategy in a trade-off between uncertainty and error, mean flight delay, and the LOS metrics (which this study equates to the potential for tactical conflict management actions). The optimal solution for a given airspace, demand level, and other factors, could likely be a combination of SCM strategies, although this study only compared the use of a single SCM strategy at a time. The CR strategy appeared to have the best opportunity for scalability by limiting the number of potential tactical actions to nearly zero.

Strategic Conflict Management↗

NASA NTRS2023

Analysis of VFR Traffic Uncertainty and its Impact on Uncrewed Aircraft Operational Capacity at Regional Airports

This paper proposes a method to characterize Visual Flight Rules traffic around a regional airport. The applicability of the method is discussed in the context of Uncrewed Aircraft operations at a regional airport. The relation between traffic interaction uncertainty and operational capacity at the runway is also investigated. The spatio-temporal distribution of traffic operating under Visual Flight Rules is analyzed from historical track data and visualized as heat maps generated at different altitudes. These are used to characterize the spatio-temporal uncertainty associated with traffic density, around a given airport, down to the runway. The traffic patterns at the runway are used to compute the runway capacity as a function of the probability of interaction with traffic operating under visual flight rules. Fort Worth Alliance is used as a representative regional airport for the study. Applications of the traffic characterization methods developed in this paper are also discussed.

VFR traffic, uncertainty, air mobility↗

NASA NTRS2023

Analysis of VFR Traffic Uncertainty and its Impact on Uncrewed Aircraft Operational Capacity at Regional Airports

VFR traffic↗

NASA NTRS2010

Airborne Dust, "The Good Guy or the Bad Guy": How Much do We Know?

Processes in generating, transporting, and dissipating the airborne dust particles are global phenomena -African dust regularly reaching the Alps; Asian dust seasonally crossing the Pacific into North America, and ultimately the Atlantic into Europe. One of the vital biogeochemical roles dust storms play in Earth's ecosystem is routinely mobilizing mineral dust, as a source of iron, from deserts into oceans for fertilizing the growth of phytoplankton -the basis of the oceanic food chain. Similarly, these dust-laden airs also supply crucial nutrients for the soil of tropical rain forests, the so-called womb of life that hosts 50-90% of the species on Earth. With massive amounts of dust lifted from desert regions and injected into the atmosphere, however, these dust storms often affect daily activities in dramatic ways: pushing grit through windows and doors, forcing people to stay indoors, causing breathing problems, reducing visibility and delaying flights, and by and large creating chaos. Thus, both increasing and decreasing concentrations of doses result in harmful biological effects; so do the airborne dust particles to our Living Earth. Since 1997 NASA has been successfully launching a series of satellites - the Earth Observing System - to intensively study, and gain a better understanding of, the Earth as an integrated system. Through participation in many satellite remote-sensing/retrieval and validation projects over the years, we have gradually developed and refined the SMART (Surface-sensing Measurements for Atmospheric Radiative Transfer) and COMMIT (Chemical, Optical & Microphysical Measurements of In-situ Troposphere) mobile observatories, a suite of surface remote sensing and in-situ instruments that proved to be vital in providing high temporal measurements, which complement the satellite observations. In this talk, we will present SMART-COMMIT which has played key roles, serving as network or supersite, in major international research projects such as the Joint Aerosol Monsoon Experiment (JAMEX), a core element of the Asian Monsoon Years (AMY, 2008-2012). SMART-COMMIT deployments during 2008 AMY/JAMEX were conducted in northwestern China to characterize the properties of dust-laden aerosols. In 2009, SMART-COMMIT also participated in the JAMEX/RAJO-MEGHA (Radiation, Aerosol Joint Observations-Monsoon Experiment in the Gangetic-Himalayan Area; Sanskrit for Dust-Cloud) to study the aerosol properties, solar absorption and the associated atmospheric warming, and the climatic impact of elevated aerosols during the premonsoon season in South Asia. To fully characterize the properties of airborne dust in the field is an important but challenging task. In this seminar, we will present our recent measurements and retrievals of airborne dust properties.

Tsay, Si-Chee↗

NASA NTRSDate not supplied

Assessing the Relationships Between Sensorimotor Biomarkers and Post-Landing Functional Task Performance

Spaceflight drives adaptive changes in healthy individuals appropriate for sensorimotor function in a microgravity environment. These changes are maladaptive for return to earth's gravity. The inter-individual variability of sensorimotor decrements is striking, although poorly understood. The goal of this study was to identify a set of behavioral, neuroimaging and genetic measures that can be used to predict early post-flight performance on a set of sensorimotor tasks. Astronauts were recruited who previously participated in sensorimotor field tests and/or posturography soon after long-duration spaceflight. Behavioral tests included assessments of sensory dependency and adaptability. Visual dependency involved treadmill walking while viewing a moving virtual visual scene. Vestibular perceptual thresholds were measured while seated during lateral translations. Proprioception dependency was measured during one-legged stance on a horizontal air-bearing surface. Ground assessment of adaptability was performed (1) during treadmill walking with a virtual linear hallway and a moving walking surface, and (2) during multiple trials of navigating an obstacle course while wearing reversing prisms (adaptive Functional Mobility Test, aFMT). The neuroimaging tests characterized individual differences in regional brain volumes (using Structural MRI) and white matter microstructure (using Diffusion Tensor Imaging) to serve as potential predictors of adaptive capacity. The genetic tests utilized saliva samples to examine variations in four genes chosen because of their ability to differentiate sensorimotor adaptation ability in a normative population, including Catechol-O-methyltransferase (COMT), Dopamine Receptor D2 (DRD2), Brain-derived neurotrophic factor (BDNF) and the α2-adrenergic receptor. Thirty ISS crewmembers were recruited, including 12 first-time fliers, 6F, and mission durations lasting 185.5 ± 45.5 days, mean ± std. We utilized a combination of three post-flight functional task outcomes: tandem walk, recovery from fall and dynamic posturography. There was considerable variability among all post-flight performance outcomes. Based on an ordinal scale survey, 72% indicated their ability to perform functional tasks were more impacted postflight relative to inflight with 50% indicating they needed to restrict movements for a longer period postflight relative to inflight. While there is a strong association within tests obtained at different R+0 timepoints, by R+24 hr performance on one post-flight test does not necessarily correlate with performance on other post-flight tests. Preliminary statistical analysis indicates combining biomarkers will increase predictive power and this will be explored with future analyses. Our preliminary findings underscore the importance of a comprehensive post-flight test battery including different types of tasks with varying sensory feedback. Understanding the relationships between these sensorimotor biomarkers and post-flight functional task performance improve both our understanding of the individual variability and our strategy to optimize sensorimotor countermeasures.

biomarkers↗

NASA NTRS2024

Assessing the Relationships Between Sensorimotor Biomarkers and Post-Landing Functional Task Performance

Spaceflight drives adaptive changes in healthy individuals appropriate for sensorimotor function in a microgravity environment. These changes are maladaptive for return to earth's gravity. The inter-individual variability of sensorimotor decrements is striking, although poorly understood. The goal of this study is to identify a set of behavioral, neuroimaging and genetic measures that can be used to predict early post-flight performance on a set of sensorimotor tasks. Astronauts are recruited who previously participated in sensorimotor field tests and/or posturography soon after long-duration spaceflight. Behavioral tests include assessments of sensory dependency and adaptability. Visual dependency involves treadmill walking while viewing a moving virtual visual scene. Vestibular perceptual thresholds are measured while seated during lateral translations. Proprioception dependency is measured during one-legged stance on a horizontal air-bearing surface. Ground assessment of adaptability is performed(1) during treadmill walking with a virtual linear hallway and a moving walking surface, and (2) during multiple trials of navigating an obstacle course while wearing reversing prisms(adaptive Functional Mobility Test, aFMT). The neuroimaging tests will characterize individual differences in regional brain volumes (using Structural MRI) and white matter microstructure(using Diffusion Tensor Imaging) to serve as potential predictors of adaptive capacity. The genetic tests will utilize saliva samples to examine variations in four genes chosen because of their ability to differentiate sensorimotor adaptation ability in a normative population, including Catechol-O-methyltransferase (COMT), Dopamine Receptor D2 (DRD2), Brain-derived neurotrophic factor (BDNF) and the α2-adrenergic receptor. Twenty-seven ISS crewmembers have been tested to date, including 6 from this past year. This cohort includes 10first-time fliers, 6F, and mission durations lasting 178.6 ± 30.5 days, mean ± std. We are utilizing a combination of three post-flight functional task outcomes: tandem walk, recovery from fall and dynamic posturography. There is considerable variability among the post-flight performance outcomes for the 27participants to date. Based on a partial sample using an ordinal scale survey, 70% indicated their ability to perform functional tasks were more impacted postflight relative to inflight with 50% indicating they needed to restrict movements for a longer period postflight relative to inflight. While there is a strong association within tests obtained at different R+0 timepoints, by R+24 hr performance on one post-flight test does not necessarily correlate with performance on other post-flight tests. There are apparent relationships between individual measures and specific post-flight outcome measures, e.g., the cumulative time to complete the aFMT is significantly correlated to pre-to-post-flight changes in tandem walk (rho= 0.64, p = 0.001). Preliminary statistical analysis indicates combining biomarkers will increase predictive power and this will be explored with future analyses. Our preliminary findings underscore the importance of a comprehensive post-flight test battery including different types of tasks with varying sensory feedback. We expect that understanding the relationships between these sensorimotor biomarkers and post-flight functional task performance will improve both our understanding of the individual variability and our strategy to optimize sensorimotor countermeasures

S J Wood↗