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A preliminary study of the Soviet civil space program. Volume 1: Organization and Operations

The organization, planning, and personnel is focused of Soviet space, advantage is taken of glasnost and improved foreign relations to explore a hitherto obscure subject. The way in which the civil space program obtains approval and funding is altered. Missions must be approved before the Supreme Soviet, and public opinion is beginning to play a greater role in the legislature's budget decision. The Soviet civil space program remains a collection of disparate elements, not unified by any national, centralized space agency. An attempt was made to catalog and delineate the relationships between the components proves helpful. There is little or no coordination of independent associations' efforts, and the planning process relied on previously to set priorities and allocate resources appears to be currently inoperative or in a state of flux. The civil space program is moving in new directions: toward budget tautness, more international interactions, an emphasis on civilian over military applications, commercialization, and fiscal accountability. This study is a snapshot of a dynamic subject, but hopefully on which has highlighted the critical elements to track.

Newton, Elizabeth K.↗

Exploring the Unknown: Selected Documents in the History of the US Civil Space Program: Organizing for Exploration - Volume 1

A selection of key documents in the history of the U.S. civil space program is presented. This volume deals with organizational developments of the space program. More than 200 documents are printed. Each is introduced by a headnote providing context, bibliographical information, and background information necessary to understanding the document. These are organized into four major sections, each beginning with an introductory essay that keys the documents to major events in the history of the space program.

Logsdon, John M.↗

Challenges and Future Opportunities in Our Nation's Space Program

For the first time in decades, there is a significant amount of change in our nation's space program. Along with change, there are opportunities, and NASA has begun a set of planning to be prepared for the future, emphasizing innovation and technology development, increased emphasis on collaboration, commercially-provided access to space, and the need for reinvention. This discussion will briefly give an overview of NASA, showcase some of the diverse activities that are part of our nation' fs space program, identify some of the new changes envisioned to NASA's mission, and how our space program can continue to inspire the nation during changing times.

Clements, Greg↗

Novel Approaches to Cellular Transplantation from the US Space Program

Research in the treatment of type I diabetes is entering a new era that takes advantage of our knowledge in an ever increasing variety of scientific disciplines. Some may originate from very diverse sources, one of which is the Space Program at National Aeronautics and Space Administration (NASA). The Space Program contributes to diabetes-related research in several treatment modalities. As an ongoing effort for medical monitoring of personnel involved in space exploration activities NASA and the extramural scientific community investigate strategies for noninvasive estimation of blood glucose levels. Part of the effort in the space protein crystal growth program is high-resolution structural analysis insulin as a means to better understand the interaction with its receptor and with host immune components and as a basis for rational design of a "better" insulin molecule. The Space Program is also developing laser technology for potential early cataract detection as well as a noninvasive analyses for addressing preclinical diabetic retinopathy. Finally, NASA developed an exciting cell culture system that affords some unique advantages in the propagation and maintenance of mammalian cells in vitro. The cell culture system was originally designed to maintain cell suspensions with a minimum of hydrodynamic and mechanical sheer while awaiting launch into microgravity. Currently the commercially available NASA bioreactor (Synthecon, Inc., Houston, TX) is used as a research tool in basic and applied cell biology. In recent years there is continued strong interest in cellular transplantation as treatment for type I diabetes. The advantages are the potential for successful long-term amelioration and a minimum risk for morbidity in the event of rejection of the transplanted cells. The pathway to successful application of this strategy is accompanied by several substantial hurdles: (1) isolation and propagation of a suitable uniform donor cell population; (2) management of host immune rejection; (3) protection from the autoimmune component of the disease; and (4) anatomic placement of the engrafted cells that permits timely response to blood sugar levels as well as effective release and deployment of insulin. Bioreactor technology may provide some critical advances for surmounting some of these scientific hurdles. The NASA bioreactor is a horizontally rotating cylinder that is completely filled with culture medium. Gaseous exchange is maintained by a concentric cylinder of permeable silicon. In slow rotation (15-25 rpm) particles of small mass such as cells and tissue aggregates remain suspended in the rotating body of fluid. This novel approach suspends cells without stirring thus, allowing objects of different size mass to colocate and interact in a very low shear environment. In fact, analysis of the forces acting on individual cells in the rotating bioreactor reveals that the cells are continuously falling through the fluid medium. The conditions in the bioreactor permit assembly of cells into aggregates. three-dimensional tissue growth, synthesis of intercellular matrix,10 differentiation, and some sinusoid formations that may serve as a surrogate vasculature for larger tissue segments.

Pellis, Neal R.↗

Human Research Program Space Radiation Standing Review Panel (SRP)

The Space Radiation Standing Review Panel (SRP) met at the NASA Johnson Space Center (JSC) on December 9-11, 2009 to discuss the areas of current and future research targeted by the Space Radiation Program Element (SRPE) of the Human Research Program (HRP). Using evidence-based knowledge as a background for identified risks to astronaut health and performance, NASA had identified gaps in knowledge to address those risks. Ongoing and proposed tasks were presented to address the gaps. The charge to the Space Radiation SRP was to review the gaps, evaluate whether the tasks addressed these gaps and to make recommendations to NASA s HRP Science Management Office regarding the SRP's review. The SRP was requested to evaluate the practicality of the proposed efforts in light of the demands placed on the HRP. Several presentations were made to the SRP during the site visit and the SRP spent sufficient time to address the SRP charge. The SRP made a final debriefing to the HRP Program Scientist, Dr. John B. Charles, on December 11, 2009. The SRP noted that current SRPE strategy is properly science-based and views this as the best assurance of the likelihood that answers to the questions posed as gaps in knowledge can be found, that the uncertainty in risk estimates can be reduced, and that a solid, cost-effective approach to risk reduction solutions is being developed. The current approach of the SRPE, based on the use of carefully focused research solicitations, requiring thorough peer-review and approaches demonstrated to be on the path to answering the NASA strategic questions, addressed to a broad extramural community of qualified scientists, optimally positioned to take advantage of serendipitous discoveries and to leverage scientific advances made elsewhere, is sound and appropriate. The SRP viewed with concern statements by HRP implying that the only science legitimately deserving support should be "applied" or, in some instances that the very term "research" might be frowned upon. We understand the desire of management to ensure that research stay focused on mission objectives, but the terms used are code words fraught with different meaning for scientists. Such expressions, taken at face value, convey a profoundly flawed view of science, can easily lead down counterproductive paths, and have the potential to irretrievably corrupt NASA requirements. The SRP understands and endorses the mandate to keep research efforts focused on the mission needs. However, thoughtful application of knowledge gained by understanding the mechanisms and pathways of biological effects cannot be replaced.

Woloschak, Gayle↗

Cost-estimating relationships for space programs

Cost-estimating relationships (CERs) are defined and discussed as they relate to the estimation of theoretical costs for space programs. The paper primarily addresses CERs based on analogous relationships between physical and performance parameters to estimate future costs. Analytical estimation principles are reviewed examining the sources of errors in cost models, and the use of CERs is shown to be affected by organizational culture. Two paradigms for cost estimation are set forth: (1) the Rand paradigm for single-culture single-system methods; and (2) the Price paradigms that incorporate a set of cultural variables. For space programs that are potentially subject to even small cultural changes, the Price paradigms are argued to be more effective. The derivation and use of accurate CERs is important for developing effective cost models to analyze the potential of a given space program.

Mandell, Humboldt C., Jr.↗

Low cost program practices for future NASA space programs, volume 1

The progress and outcomes of a NASA/HQ indepth analysis of NASA program practices are documented. Included is a survey of NASA and industry reaction to the utility and application of a Program Effects Relationship Handbook. The results and outcomes of all study tasks are presented as engineering memoranda as the appendix.

Source record↗

United State space programs - Present and planned

The U.S. space program is considered with reference to the benefits derived by the public. Missions are divided into three categories: the use of near-earth space for remote sensing, communications, and other purposes directly beneficial to human welfare; the scientific exploration of the solar system and observation of the universe as part of the continuing effort to understand the place of earth and man in the cosmos; and the investigation of the sun-earth relationships which are basic to the terrestrial biosphere. Individual projects are described, and it is suggested that the future of space technology in 1978 is comparable to the future of aviation in 1924.

Frosch, R. A.↗

Implications of Public Opinion for Space Program Planning, 1980 - 2000

The effect of public opinion on future space programs is discussed in terms of direct support, apathy, or opposition, and concern about the tax burden, budgetary pressures, and national priorities. Factors considered include: the salience and visibility of NASA as compared with other issues, the sources of general pressure on the federal budget which could affect NASA, the public's opinions regarding the size and priority of NASA'S budget, the degree to which the executive can exercise leverage over NASA's budget through influencing or disregarding public opinion, the effects of linkages to other issues on space programs, and the public's general attitudes toward the progress of science.

Overholt, W.↗