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At least 919 records · Page 51

Internal Fiducial Markers and Susceptibility Effects in MRI-Simulation and Measurement of Spatial Accuracy

Background: It is well-known that magnetic resonance imaging (MRI) is preferable to computed tomography (CT) in radiotherapy target delineation. To benefit from this, there are two options available: transferring the MRI delineated target volume to the planning CT or performing the treatment planning directly on the MRI study. A precondition for excluding the CT study is the possibility to define internal structures visible on both the planning MRI and on the images used to position the patient at treatment. In prostate cancer radiotherapy, internal gold markers are commonly used, and they are visible on CT, MRI, x-ray, and portal images. The depiction of the markers in MRI are, however, dependent on their shape and orientation relative the main magnetic field because of susceptibility effects. In the present work, these effects are investigated and quantified using both simulations and phantom measurements. Methods and Materials: Software that simulated the magnetic field distortions around user defined geometries of variable susceptibilities was constructed. These magnetic field perturbation maps were then reconstructed to images that were evaluated. The simulation software was validated through phantom measurements of four commercially available gold markers of different shapes and one in-house gold marker. Results: Both simulations and phantom measurements revealed small position deviations of the imaged marker positions relative the actual marker positions (<1 mm). Conclusion: Cylindrical gold markers can be used as internal fiducial markers in MRI.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

Molecular Dynamics Simulation of Complex Reactivity with the Rapid Approach for Proton Transport and Other Reactions (RAPTOR) Software Package

Simulating chemically reactive phenomena such as proton transport on nanosecond to microsecond and beyond time scales is a challenging task. Ab initio methods are unable to currently access these time scales routinely, and traditional molecular dynamics methods feature fixed bonding arrangements that cannot account for changes in the system’s bonding topology. The Multiscale Reactive Molecular Dynamics (MS-RMD) method, as implemented in the Rapid Approach for Proton Transport and Other Reactions (RAPTOR) software package for the LAMMPS molecular dynamics code, offers a method to routinely sample longer time scale reactive simulation data with statistical precision. RAPTOR may also be interfaced with enhanced sampling methods to drive simulations toward the analysis of reactive rare events, and a number of collective variables (CVs) have been developed to facilitate this. Key advances to this methodology, including GPU acceleration efforts and novel CVs to model water wire formation are reviewed, along with recent applications of the method which demonstrate its versatility and robustness.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Software life cycle dynamic simulation model: The organizational performance submodel

The submodel structure of a software life cycle dynamic simulation model is described. The software process is divided into seven phases, each with product, staff, and funding flows. The model is subdivided into an organizational response submodel, a management submodel, a management influence interface, and a model analyst interface. The concentration here is on the organizational response model, which simulates the performance characteristics of a software development subject to external and internal influences. These influences emanate from two sources: the model analyst interface, which configures the model to simulate the response of an implementing organization subject to its own internal influences, and the management submodel that exerts external dynamic control over the production process. A complete characterization is given of the organizational response submodel in the form of parameterized differential equations governing product, staffing, and funding levels. The parameter values and functions are allocated to the two interfaces.

Tausworthe, Robert C.↗

Model for Simulating a Spiral Software-Development Process

A discrete-event simulation model, and a computer program that implements the model, have been developed as means of analyzing a spiral software-development process. This model can be tailored to specific development environments for use by software project managers in making quantitative cases for deciding among different software-development processes, courses of action, and cost estimates. A spiral process can be contrasted with a waterfall process, which is a traditional process that consists of a sequence of activities that include analysis of requirements, design, coding, testing, and support. A spiral process is an iterative process that can be regarded as a repeating modified waterfall process. Each iteration includes assessment of risk, analysis of requirements, design, coding, testing, delivery, and evaluation. A key difference between a spiral and a waterfall process is that a spiral process can accommodate changes in requirements at each iteration, whereas in a waterfall process, requirements are considered to be fixed from the beginning and, therefore, a waterfall process is not flexible enough for some projects, especially those in which requirements are not known at the beginning or may change during development. For a given project, a spiral process may cost more and take more time than does a waterfall process, but may better satisfy a customer's expectations and needs. Models for simulating various waterfall processes have been developed previously, but until now, there have been no models for simulating spiral processes. The present spiral-process-simulating model and the software that implements it were developed by extending a discrete-event simulation process model of the IEEE 12207 Software Development Process, which was built using commercially available software known as the Process Analysis Tradeoff Tool (PATT). Typical inputs to PATT models include industry-average values of product size (expressed as number of lines of code), productivity (number of lines of code per hour), and number of defects per source line of code. The user provides the number of resources, the overall percent of effort that should be allocated to each process step, and the number of desired staff members for each step. The output of PATT includes the size of the product, a measure of effort, a measure of rework effort, the duration of the entire process, and the numbers of injected, detected, and corrected defects as well as a number of other interesting features. In the development of the present model, steps were added to the IEEE 12207 waterfall process, and this model and its implementing software were made to run repeatedly through the sequence of steps, each repetition representing an iteration in a spiral process. Because the IEEE 12207 model is founded on a waterfall paradigm, it enables direct comparison of spiral and waterfall processes. The model can be used throughout a software-development project to analyze the project as more information becomes available. For instance, data from early iterations can be used as inputs to the model, and the model can be used to estimate the time and cost of carrying the project to completion.

Mizell, Carolyn↗

Development and Demonstration of Material Properties Database and Software for the Simulation of Flow Properties in Cementitious Materials

This report describes work performed by the Savannah River National Laboratory (SRNL) in fiscal year 2014 to develop a new Cementitious Barriers Project (CBP) software module designated as FLOExcel. FLOExcel incorporates a uniform database to capture material characterization data and a GoldSim model to define flow properties for both intact and fractured cementitious materials and estimate Darcy velocity based on specified hydraulic head gradient and matric tension. The software module includes hydraulic parameters for intact cementitious and granular materials in the database and a standalone GoldSim framework to manipulate the data. The database will be updated with new data as it comes available. The software module will later be integrated into the next release of the CBP Toolbox, Version 3.0. This report documents the development efforts for this software module. The FY14 activities described in this report focused on the following two items that form the FLOExcel package; 1) Development of a uniform database to capture CBP data for cementitious materials. In particular, the inclusion and use of hydraulic properties of the materials are emphasized; and 2) Development of algorithms and a GoldSim User Interface to calculate hydraulic flow properties of degraded and fractured cementitious materials. Hydraulic properties are required in a simulation of flow through cementitious materials such as Saltstone, waste tank fill grout, and concrete barriers. At SRNL these simulations have been performed using the PORFLOW code as part of Performance Assessments for salt waste disposal and waste tank closure.

97 MATHEMATICS AND COMPUTING↗

A real-time dynamic spacecraft simulator for the LANDSAT-D mission

A real time dynamic simulator for LANDSAT D was developed and has played an integral role in the development and validation of both the ground control system and of the on-board flight software. The simulator utilized an electronic replica of the spacecraft on-board computer and data handling hardware interfaced to a VAX 11/780 computer and simulation software. Key features of the simulator design are a modular software architecture tailored to the VAX/VMS real time capabilities, a microprocessor controlled interface between the VAX and the flight hardware replica, complete simulation of the spacecraft and NASA network communication links, and a flexible and powerful scenario structuring and operator control capability. The design goals and trade-offs, software, and hardware design are summarized. The application of the simulator to the validation of both the ground systems and on-board software is reviewed in detail.

Coffin, A. R.↗

Verification and Validation of Simulation Models for High-Speed Flow Fields

This paper is largely based on the paper titled "Guide to Credible Computational Fluid Dynamics Simulations (Invited)" (AIAA Paper 95-2225). The significance of computational fluid dynamics (CFD) simulations depends solely on their credibility. A customer of CFD products -- simulations and software -- expects that these products are credible for the intended use. Simulation model verification and validation are critical in establishing the credibility of simulations and in certifying simulation software. The only thing that matters in establishing the credibility is uncertainty, not veracity or validity. The sensitivity-uncertainty analysis is the key to the establishment of this credibility. Assessing the credibility of complex simulation results poses a significant challenge. Terminology, concepts, framework, and guidelines are presented for addressing this challenge. Verification assesses whether the problem is solved correctly and estimates the level of computational accuracy of simulations; validation determines whether the right problem is solved and assesses the level of validity of the simulation model by estimating the degree to which simulations accurately represent reality. These concepts and the related guidelines are discussed with examples from high-speed flow fields.

Mehta, Unmeel B.↗

Avionics Simulation, Development and Software Engineering

This monthly report summarizes the work performed under contract NAS8-00114 for Marshall Space Flight Center in the following tasks: 1) Purchase Order No. H-32831D, Task Order 001A, GPB Program Software Oversight; 2) Purchase Order No. H-32832D, Task Order 002, ISS EXPRESS Racks Software Support; 3) Purchase Order No. H-32833D, Task Order 003, SSRMS Math Model Integration; 4) Purchase Order No. H-32834D, Task Order 004, GPB Program Hardware Oversight; 5) Purchase Order No. H-32835D, Task Order 005, Electrodynamic Tether Operations and Control Analysis; 6) Purchase Order No. H-32837D, Task Order 007, SRB Command Receiver/Decoder; and 7) Purchase Order No. H-32838D, Task Order 008, AVGS/DART SW and Simulation Support

Francis, Ronald C.↗

VULCAN-CFD User Manual: Ver. 7.2.0

VULCAN-CFD offers a comprehensive set of capabilities to enable the simulation of continuum flowfields from subsonic to hypersonic conditions. The governing equations that are employed include allowances for both chemical and thermal nonequilibrium processes, coupled with a wide variety of turbulence models for both Reynolds-averaged and large eddy simulations. The software package can simulate two-dimensional, axisymmetric, or three-dimensional problems on structured multiblock meshes or fully unstructured meshes. A parabolic (i.e., space-marching) treatment can also be used for any subset of a structured mesh that can accommodate this solution strategy. The flow solver provides a significant level of geometric flexibility for structured grid simulations by allowing for arbitrary face-to-face C(0) continuous and non-C(0) continuous block interface connectivities. The unstructured grid paradigm allows for mixed element unstructured meshes that contain any combination of tetrahedral, prismatic, pyramidal, and hexahedral cell elements. The flow solver is also fully parallelized using MPI (Message Passing Interface) libraries in a data-parallel fashion, allowing for efficient simulations on modern High Performance Computing (HPC) systems. This document provides information related to the installation and execution of the VULCAN-CFD software package. A detailed description of the physical and numerical models available in the software are provided in the VULCAN-CFD Theory Manual.

VULCAN-CFD User Manual↗

Microprocessor software applications for flight training simulators

The g cueing system software design and implementation in the dual microprocessor system of the F-15 operational flight training simulator g cueing system is presented. The software is structured in the two microcomputers such that one serves as a controller performing all logical functions and interface with the host computer system while the other serves as an arithmetic unit performing all mathematical functions.

Leavy, W. P.↗

Investigating the XENON1T low-energy electronic recoil excess using NEST

The search for dark matter, the missing mass of the Universe, is one of the most active fields of study within particle physics. The XENON1T experiment recently observed a 3.5⁢𝜎 excess potentially consistent with dark matter, or with solar axions. Here, we will use the Noble Element Simulation Technique (NEST) software to simulate the XENON1T detector, reproducing the excess. We utilize different detector efficiency and energy reconstruction models, but they primarily impact sub-keV energies and cannot explain the XENON1T excess. However, using NEST, we can reproduce their excess in multiple, unique ways, most easily via the addition of 31 ± 11 37 Ar decays. Furthermore, this results in new, modified background models, reducing the significance of the excess to ≤2.2⁢𝜎 at least using non-Profile Likelihood Ratio (PLR) methods. This is independent confirmation that the excess is a real effect, but potentially explicable by known physics. Many cross-checks of our 37 Ar hypothesis are presented.

particle dark matter↗

Photovoltaic array performance and life-cycle cost simulation using new software tools

The three computer models, SAMICS, PVARRAY, and LCP can be used together as a single analytical tool to compare the lifetime economic value of a photovoltaic (PV) array. This evaluation can be used to compare various module and array configurations and the performance characteristics of different module manufacturing technologies.

Daniel, R. E.↗

A large scale software system for simulation and design optimization of mechanical systems

The concept of an advanced integrated, networked simulation and design system is outlined. Such an advanced system can be developed utilizing existing codes without compromising the integrity and functionality of the system. An example has been used to demonstrate the applicability of the concept of the integrated system outlined here. The development of an integrated system can be done incrementally. Initial capabilities can be developed and implemented without having a detailed design of the global system. Only a conceptual global system must exist. For a fully integrated, user friendly design system, further research is needed in the areas of engineering data bases, distributed data bases, and advanced user interface design.

Dopker, Bernhard↗

Software engineering and simulation

This paper summarizes the development of several automatic programming systems for discrete event simulation. Emphasis is given on the model development, or problem definition, and the model writing phases of the modeling life cycle.

Zhang, Shou X.↗

Software For Numerical Simulation Of Geophysical Flows

Program verified by comparisons with both experimental and numerical studies. GEOSIM implements numerical model simulating geophysical fluid flow for wide range of problems. Allows for more accurate control over experimental conditions and provides complete data source for performing diagnostic studies. Used by experienced and/or professional fluid dynamicists. Written in FORTRAN 77.

Miller, Timothy L.↗

Avionics Simulation, Development and Software Engineering

During this reporting period, all technical responsibilities were accomplished as planned. A close working relationship was maintained with personnel of the MSFC Avionics Department Software Group (ED14), the MSFC EXPRESS Project Office (FD31), and the Huntsville Boeing Company. Accomplishments included: performing special tasks; supporting Software Review Board (SRB), Avionics Test Bed (ATB), and EXPRESS Software Control Panel (ESCP) activities; participating in technical meetings; and coordinating issues between the Boeing Company and the MSFC Project Office.

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