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Development of a rhesus monkey lung geometry model and application to particle deposition in comparison to humans
The exposure-dose-response characterization of an inhalation hazard established in an animal species needs to be translated to an equivalent characterization in humans relative to comparable doses or exposure scenarios. Here, the first geometry model of the conducting airways for rhesus monkeys is developed based upon CT images of the conducting airways of a 6-month-old male, rhesus monkey. An algorithm was developed for adding the alveolar region airways using published rhesus morphometric data. The resultant lung geometry model can be used in mechanistic particle or gaseous dosimetry models. Such dosimetry models require estimates of the upper respiratory tract volume of the animal and the functional residual capacity, as well as of the tidal volume and breathing frequency of the animal. The relationship of these variables to rhesus monkeys of differing body weights was established by synthesizing and modeling published data as well as modeling pulmonary function measurements on 121 rhesus control animals. Deposition patterns of particles up to 10 µm in size were examined for endotracheal and and up to 5 µm for spontaneous breathing in infant and young adult monkeys and compared to those for humans. Deposition fraction of respirable size particles was found to be higher in the conducting airways of infant and young adult rhesus monkeys compared to humans. Due to the filtering effect of the conducting airways, pulmonary deposition in rhesus monkeys was lower than that in humans. Finally, future research areas are identified that would either allow replacing assumptions or improving the newly developed lung model.
On the rotational bursting of interplanetary dust particles
A model of the zodiacal cloud is used to evaluate the effects of rotational bursting on interplanetary dust particles caused by the interaction of solar radiation pressure with the irregular surface geometry of the particles. The effectiveness of this mechanism is evaluated using several values for the effective moment arm and tensile strength of the particles. Due to repeated bursting, it is shown that particles spiraling in from the asteroid belt by the Poynting-Robertson effect do not penetrate inside 1.2 AU. Spin rate stabilization under the effect of magnetic damping is found to depend critically on the initial heliocentric distance of the particle and on its radius.
A simple model for perturbative kinetic particle resonances in tokamaks
Resonances driven by particle distribution gradients are studied in a simple statistical model which does not involve advancing individual particles due to the interaction with the mode. The phase-space structure of resonances and the associated modification of density profiles in tokamaks are due to equilibration between the bounce averaging of particles within the resonance, which tends to locally flatten the distribution, particle collisions, which tend to re-establish the original density gradients, and wave background damping, which extracts energy from the mode. Modes are perturbatively driven while the distribution is irreversibly modified due to diffusion within the resonance, where local properties of the equilibrium and particle distribution are sufficient to determine the time evolution of a mode. As a result, simulations replicate the expected scaling with the collision frequency of mode saturation amplitudes and collisional broadening of the density modification and give reasonable agreement with saturation amplitudes given by full guiding center simulations.
Modelling non-equilibrium secondary organic aerosol formation and evaporation with the aerosol dynamics, gas- and particle-phase chemistry kinetic multilayer model ADCHAM
We have developed the novel Aerosol Dynamics, gas- and particle- phase chemistry model for laboratory CHAMber studies (ADCHAM). The model combines the detailed gas phase Master Chemical Mechanism version 3.2, an aerosol dynamics and particle phase chemistry module (which considers acid catalysed oligomerization, heterogeneous oxidation reactions in the particle phase and non-ideal interactions between organic compounds, water and inorganic ions) and a kinetic multilayer module for diffusion limited transport of compounds between the gas phase, particle surface and particle bulk phase. In this article we describe and use ADCHAM to study: 1) the mass transfer limited uptake of ammonia (NH3) and formation of organic salts between ammonium (NH4+) and carboxylic acids (RCOOH), 2) the slow and almost particle size independent evaporation of α-pinene secondary organic aerosol (SOA) particles, and 3) the influence of chamber wall effects on the observed SOA formation in smog chambers.
Turbulence Evolution and Shock Acceleration of Solar Energetic Particles
We model the effects of self-excitation/damping and shock transmission of Alfven waves on solar-energetic-particle (SEP) acceleration at a coronal-mass-ejection (CME) driven parallel shock. SEP-excited outward upstream waves speedily bootstrap acceleration. Shock transmission further raises the SEP-excited wave intensities at high wavenumbers but lowers them at low wavenumbers through wavenumber shift. Downstream, SEP excitation of inward waves and damping of outward waves tend to slow acceleration. Nevertheless, > 2000 km/s parallel shocks at approx. 3.5 solar radii can accelerate SEPs to 100 MeV in < 5 minutes.
Fully explicit nonlinear optics model in a particle-in-cell framework
A numerical technique which incorporates the nonlinear optics of anisotropic crystals into a particle-in-cell framework is described. The model is useful for simulating interactions between crystals, ultra-short laser pulses, intense relativistic electron bunches, plasmas, or any combination thereof. The frequency content of the incident and scattered radiation is limited only by the resolution of the spatial and temporal grid. A numerical stability analysis indicates that the Courant condition is more stringent than in the vacuum case. Numerical experiments are carried out illustrating the electro-optic effect, soliton propagation, and the generation of fields in a crystal by a relativistic electron bunch.
Space Shuttle and Launch Pad Computational Fluid Dynamics Model for Lift-off Debris Transport Analysis
This paper discusses the Space Shuttle Lift-off CFD model developed for potential Lift-off Debris transport for return-to-flight. The Lift-off portion of the flight is defined as the time starting with tanking of propellants until tower clear, approximately T0+6 seconds, where interactions with the launch pad cease. A CFD model containing the Space Shuttle and launch Pad geometry has been constructed and executed. Simplifications required in the construction of the model are presented and discussed. A body-fitted overset grid of up to 170 million grid points was developed which allowed positioning of the Vehicle relative to the Launch Pad over the first six seconds of Climb-Out. The CFD model works in conjunction with a debris particle transport model and a debris particle impact damage tolerance model. These models have been used to assess the interactions of the Space Shuttle plumes, the wind environment, and their interactions with each other and the Launch Pad and their ultimate effect on potential debris during Lift-off.
Space Shuttle and Launch Pad Lift-Off Debris Transport Analysis: SRB Plume-Driven
This paper discusses the Space Shuttle Lift-Off model developed for potential Lift-Off Debris transport. A critical Lift-Off portion of the flight is defined from approximately 1.5 sec after SRB Ignition up to 'Tower Clear', where exhaust plume interactions with the Launch Pad occur. A CFD model containing the Space Shuttle and Launch Pad geometry has been constructed and executed. The CFD model works in conjunction with a debris particle transport model and a debris particle impact damage tolerance model. These models have been used to assess the effects of the Space Shuttle plumes, the wind environment, their interactions with the Launch Pad, and their ultimate effect on potential debris during Lift-Off. Emphasis in this paper is on potential debris that might be caught by the SRB plumes.
Halo formation and emittance growth in the transport of spherically symmetric mismatched bunched beams
The effect of an initial envelope mismatch on the transport of bunched spherically symmetric beams is investigated. A particle-core model is used to estimate the maximum radius that halo particles can reach. The theory is used to obtain an empirical formula that provides the halo size as a function of system parameters. Taking into account, the incompressibility property of the Vlasov dynamics and the resulting Landau damping, an explicit form for the final stationary distribution attained by the beam is proposed. The distribution is fully self-consistent, presenting no free fitting parameters. The theory is used to predict the relevant beam transport properties, such as the final particle density distribution, the emittance growth, and the fraction of particles that will be expelled to form halo. The theoretical results are compared to the explicit N-particle dynamics simulations, showing a good agreement.
Integrating particle flavor into deep learning models for hadronization
Hadronization models used in event generators are physics-inspired functions with many tunable parameters. Since we do not understand hadronization from first principles, there have been multiple proposals to improve the accuracy of hadronization models by utilizing more flexible parametrizations based on neural networks. These recent proposals have focused on the kinematic properties of hadrons, but a full model must also include particle flavor. In this paper, we show how to build a deep learning-based hadronization model that includes both kinematic (continuous) and flavor (discrete) degrees of freedom. Our approach is based on generative adversarial networks and we show the performance within the context of the cluster hadronization model within the erwig event generator.
Discrete Element Modeling of Triboelectrically Charged Particles
Tribocharging of particles is common in many processes including fine powder handling and mixing, printer toner transport and dust extraction. In a lunar environment with its high vacuum and lack of water, electrostatic forces are an important factor to consider when designing and operating equipment. Dust mitigation and management is critical to safe and predictable performance of people and equipment. The extreme nature of lunar conditions makes it difficult and costly to carry out experiments on earth which are necessary to better understand how particles gather and transfer charge between each other and with equipment surfaces. DEM (Discrete Element Modeling) provides an excellent virtual laboratory for studying tribocharging of particles as well as for design of devices for dust mitigation and for other purposes related to handling and processing of lunar regolith. Theoretical and experimental work has been performed pursuant to incorporating screened Coulombic electrostatic forces into EDEM, a commercial DEM software package. The DEM software is used to model the trajectories of large numbers of particles for industrial particulate handling and processing applications and can be coupled with other solvers and numerical models to calculate particle interaction with surrounding media and force fields. While simple Coulombic force between two particles is well understood, its operation in an ensemble of particles is more complex. When the tribocharging of particles and surfaces due to frictional contact is also considered, it is necessary to consider longer range of interaction of particles in response to electrostatic charging. The standard DEM algorithm accounts for particle mechanical properties and inertia as a function of particle shape and mass. If fluid drag is neglected, then particle dynamics are governed by contact between particles, between particles and equipment surfaces and gravity forces. Consideration of particle charge and any tribocharging and electric field effects requires calculation of the forces due to these effects.
Two loop neutrino model and dark matter particles with global B−L symmetry
We study a two loop induced seesaw model with global U(1){sub B−L} symmetry, in which we consider two component dark matter particles. The dark matter properties are investigated together with some phenomenological constraints such as electroweak precision test, neutrino masses and mixing and lepton flavor violation. In particular, the mixing angle between the Standard Model like Higgs and an extra Higgs is extremely restricted by the direct detection experiment of dark matter. We also discuss the contribution of Goldstone boson to the effective number of neutrino species ΔN{sub eff} ≈ 0.39 which has been reported by several experiments.
Colloid Particle Adhesion to Surfaces: Modeling and Experiments
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Neutrino-Argon Cross Sections in MicroBooNE: Measurements Spanning Multiple Interaction Channels, Final States, and Neutrino Fluxes
Neutrinos are one of the most elusive particles in the Standard Model of particle physics due to their tiny interaction cross section, which makes them challenging to detect and study. There are three known flavors of neutrinos, and any given neutrino probabilistically oscillates between them as a function of the particle's energy and propagation distance. Experimental characterization of these oscillations elucidates fundamental properties of the neutrino and the Standard Model. Meeting the precision goals of ongoing and future oscillation measurements requires detailed modeling of the way neutrinos interact with nuclear matter. Precision modeling of these interactions is a challenging theoretical problem, rich with intricate physics effects to explore, and requires input from equally precise measurements of neutrino-nucleus interaction cross sections spanning a broad range of scattering channels. To fill this need, there is an ongoing multi-experiment effort to measure these cross sections across energies, interaction channels, and nuclear targets. This thesis describes three analyses reporting neutrino-argon cross section measurements with data from the MicroBooNE liquid argon time projection chamber detector. These span multiple interaction channels, final state topologies, and neutrino fluxes. The first analysis is a set of inclusive charged current muon neutrino cross section measurements for final states with and without protons, which provides a unique view of the hadronic final state produced in these interactions. Second is a set of cross section measurements for neutral current neutral pion production, which provides a vital dataset on this under-characterized channel. Third is significant progress on measuring neutrinos produced by kaons decaying at rest, which represents a unique opportunity to measure cross sections with a mono-energetic flux of neutrinos. These measurements are accompanied by a modeling study in the GiBUU theory framework, which probes the sensitivity of the muon neutrino and pion production measurements to the modeling of nucleon-nucleon final state interactions in neutrino-nucleus scattering.
Coupling vector and pseudoscalar mesons to study baryon resonances
A study of meson-baryon systems with total strangeness -1 is made within a framework based on the chiral and hidden local symmetries. These systems consist of octet baryons, pseudoscalar and vector mesons. The pseudoscalar meson-baryon (PB) dynamics has been earlier found determinant for the existence of some strangeness -1 resonances, for example, {Lambda}(1405), {Lambda}(1670), etc. The motivation of the present work is to study the effect of coupling the closed vector meson-baryon (VB) channels to these resonances. To do this, we obtain the PB{yields}PB and VB{yields}VB amplitudes from the t-channel diagrams and the PB{r_reversible}VB amplitudes are calculated using the Kroll-Ruddermann term where, considering the vector meson dominance phenomena, the photon is replaced by a vector meson. The calculations done within this formalism reveal a very strong coupling of the VB channels to the {Lambda}(1405) and {Lambda}(1670). In the isospin 1 case, we find evidence for a double pole structure of the {Sigma}(1480) which, like the isospin 0 resonances, is also found to couple strongly to the VB channels. The strong coupling of these low-lying resonances to the VB channels can have important implications on certain reactions producing them.
Nuclear Matrix Model: A path to nuclear physics from superstrings
We derive nuclear forces and nuclear density saturation from large N{sub c} QCD, by applying AdS/CFT correspondence of string theory, called holographic QCD. This is made possible by a new description of a multi-baryon system in the holographic QCD. The description employs a matrix quantum mechanics which can be derived via the correspondence. This talk is based on collaboration work with N. Iizuka and P. Yi [1], with N. Iizuka [2, 3] and with T. Morita [4].