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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 937 records · Page 52

Predicting chronic postsurgical pain: current evidence and a novel program to develop predictive biomarker signatures

Chronic pain affects more than 50 million Americans. Treatments remain inadequate, in large part, because the pathophysiological mechanisms underlying the development of chronic pain remain poorly understood. Pain biomarkers could potentially identify and measure biological pathways and phenotypical expressions that are altered by pain, provide insight into biological treatment targets, and help identify at-risk patients who might benefit from early intervention. Biomarkers are used to diagnose, track, and treat other diseases, but no validated clinical biomarkers exist yet for chronic pain. To address this problem, the National Institutes of Health Common Fund launched the Acute to Chronic Pain Signatures (A2CPS) program to evaluate candidate biomarkers, develop them into biosignatures, and discover novel biomarkers for chronification of pain after surgery. This article discusses candidate biomarkers identified by A2CPS for evaluation, including genomic, proteomic, metabolomic, lipidomic, neuroimaging, psychophysical, psychological, and behavioral measures. Acute to Chronic Pain Signatures will provide the most comprehensive investigation of biomarkers for the transition to chronic postsurgical pain undertaken to date. Data and analytic resources generatedby A2CPS will be shared with the scientific community in hopes that other investigators will extract valuable insights beyond A2CPS’s initial findings. This article will review the identified biomarkers and rationale for including them, the current state of the science on biomarkers of the transition from acute to chronic pain, gaps in the literature, and how A2CPS will address these gaps.

60 APPLIED LIFE SCIENCES↗

Safety and Mission Assurance Knowledge Management Retention: Managing Knowledge for Successful Mission Operations

Knowledge Management is a proactive pursuit for the future success of any large organization faced with the imminent possibility that their senior managers/engineers with gained experiences and lessons learned plan to retire in the near term. Safety and Mission Assurance (S&MA) is proactively pursuing unique mechanism to ensure knowledge learned is retained and lessons learned captured and documented. Knowledge Capture Event/Activities/Management helps to provide a gateway between future retirees and our next generation of managers/engineers. S&MA hosted two Knowledge Capture Events during 2005 featuring three of its retiring fellows (Axel Larsen, Dave Whittle and Gary Johnson). The first Knowledge Capture Event February 24, 2005 focused on two Safety and Mission Assurance Safety Panels (Space Shuttle System Safety Review Panel (SSRP); Payload Safety Review Panel (PSRP) and the latter event December 15, 2005 featured lessons learned during Apollo, Skylab, and Space Shuttle which could be applicable in the newly created Crew Exploration Vehicle (CEV)/Constellation development program. Gemini, Apollo, Skylab and the Space Shuttle promised and delivered exciting human advances in space and benefits of space in people s everyday lives on earth. Johnson Space Center's Safety & Mission Assurance team work over the last 20 years has been mostly focused on operations we are now beginning the Exploration development program. S&MA will promote an atmosphere of knowledge sharing in its formal and informal cultures and work processes, and reward the open dissemination and sharing of information; we are asking "Why embrace relearning the "lessons learned" in the past?" On the Exploration program the focus will be on Design, Development, Test, & Evaluation (DDT&E); therefore, it is critical to understand the lessons from these past programs during the DDT&E phase.

Johnson, Teresa A.↗

X-ray Intermolecular Structure Factor (XISF): separation of intra- and intermolecular interactions from total X-ray scattering data

XISF is a MATLAB program developed to separate intermolecular structure factors from total X-ray scattering structure factors for molecular liquids and amorphous solids. The program is built on a trust-region-reflective optimization routine with the r.m.s. deviations of atoms physically constrained. XISF has been optimized for performance and can separate intermolecular structure factors of complex molecules.

MATLAB↗

Professional Development for Technical Managers [Slides] (Rev. 1)

LANL is changing rapidly and requires a leadership development program in order to support the growing and changing workforce. Provide analysis and recommendations for a leadership development program for engineering services within ALDFO: 1) Attrition and churn are up; 2) Younger workforce--loss of organizational knowledge; 3) LANL is geographically isolated; 4) Leadership training is infrequent and one-size-fits-all.

96 KNOWLEDGE MANAGEMENT AND PRESERVATION↗

Northwest Energy Efficient Manufactured Housing Program Specification Development

The DOE research team Building America Partnership for Improved Residential Construction (BA-PIRC), Bonneville Power Administration (BPA), and Northwest Energy Works (NEW), the current Northwest Energy Efficient Manufactured Home Program (NEEM) program administrator, collaborated to research a new specification that would reduce the energy requirements of a NEEM home.This research identified and developed combinations of cost-effective high performance building assemblies and mechanical systems that can readily can be deployed in the manufacturing setting that reduce energy used for space conditioning, water heating and lighting by 50% over the present NEEM specifications.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

Enhancing Systems Engineering Education Through Case Study Writing

Developing and refining methods for teaching systems engineering is part of Systems Engineering grand challenges and agenda for research in the SE research community. Retention of systems engineering knowledge is a growing concern in the United States as the baby boom generation continues to retire and the faster pace of technology development does not allow for younger generations to gain experiential knowledge through years of practice. Government agencies, including the National Aeronautics and Space Administration (NASA), develop their own curricula and SE leadership development programs to "grow their own" systems engineers. Marshall Space Flight Center (MSFC) conducts its own Center-focused Marshall Systems Engineering Leadership Development Program (MSELDP), a competitive program consisting of coursework, a guest lecture series, and a rotational assignment into an unfamiliar organization engaged in systems engineering. Independently, MSFC developed two courses to address knowledge retention and sharing concerns: Real World Marshall Mission Success course and its Case Study Writers Workshop and Writers Experience. Teaching case study writing and leading students through a hands-on experience at writing a case study on an SE topic can enhance SE training and has the potential to accelerate the transfer of experiential knowledge. This paper is an overview of the pilot experiences with teaching case study writing, its application in case study-based learning, and identifies potential areas of research and application for case study writing in systems engineering education.

Stevens, Jennifer Stenger↗

Space shuttle propulsion estimation development verification, volume 1

The results of the Propulsion Estimation Development Verification are summarized. A computer program developed under a previous contract (NAS8-35324) was modified to include improved models for the Solid Rocket Booster (SRB) internal ballistics, the Space Shuttle Main Engine (SSME) power coefficient model, the vehicle dynamics using quaternions, and an improved Kalman filter algorithm based on the U-D factorized algorithm. As additional output, the estimated propulsion performances, for each device are computed with the associated 1-sigma bounds. The outputs of the estimation program are provided in graphical plots. An additional effort was expended to examine the use of the estimation approach to evaluate single engine test data. In addition to the propulsion estimation program PFILTER, a program was developed to produce a best estimate of trajectory (BET). The program LFILTER, also uses the U-D factorized algorithm form of the Kalman filter as in the propulsion estimation program PFILTER. The necessary definitions and equations explaining the Kalman filtering approach for the PFILTER program, the models used for this application for dynamics and measurements, program description, and program operation are presented.

Rogers, Robert M.↗

Development and Demonstration of a 25 Watt Thermophotovoltaic Power Source for a Hybrid Power System

The development of a propane-fueled, 25 W thermophotovoltaic (TPV) power source for use in a hybrid power system is described. The TPV power source uses a platinum emitting surface with an anti-reflective coating to radiate to gallium antimonide photocells, which converts the radiation to electric power. The development program started with the design and fabrication of an engineering prototype system. This was used as a component development vehicle to develop the technologies for the various components. A 25 W demonstration prototype was then designed and fabricated using the most advanced component approaches. The designs and test results from this development program are discussed.

Doyle, Edward↗

Software For Computing Reliability Of Other Software

Computer Aided Software Reliability Estimation (CASRE) computer program developed for use in measuring reliability of other software. Easier for non-specialists in reliability to use than many other currently available programs developed for same purpose. CASRE incorporates mathematical modeling capabilities of public-domain Statistical Modeling and Estimation of Reliability Functions for Software (SMERFS) computer program and runs in Windows software environment. Provides menu-driven command interface; enabling and disabling of menu options guides user through (1) selection of set of failure data, (2) execution of mathematical model, and (3) analysis of results from model. Written in C language.

Nikora, Allen↗

Methods for Developing Successful Systems Engineers

Systems Engineering (SE) is a complex and challenging field that incorporates the knowledge of systems engineering processes, the ability to synthesize a wide-range of engineering disciplines, and the ability to lead a team of people to successfully accomplish the goals of a project. It requires hard technical skills and soft-skill leadership savvy. As a result, three main development needs are identified: 1) Knowledge of SE processes, the benefits of these processes to a project and their tailored application 2) Knowledge of a wide-range of engineering disciplines, how they interrelate in a system, and the development of sound technical judgement 3) Team leadership to direct and motivate a team of subsystem and discipline experts This paper describes the establishment of a comprehensive training and development program for Systems Engineers at NASA Ames Research Center that addresses in part each of these three areas from the perspective of the implementing manager. A variety of methods have been utilized including the establishment of a SE Community of Practice, a unique and innovative web tool, on-line videos, classroom training in NASA’s 17 Common Technical Processes, guidance on the tailored application of these processes, monthly technical talks, mentoring in both technical judgment and team leadership, and NASA’s Leadership Development Programs. While much of professional SE development must come through project experience, the approaches listed above can accelerate development. The diversity of skills required of Systems Engineering demands a multi-faceted approach to successfully train and develop this critical skill.

development↗

Methods for Developing Successful Systems Engineers

Systems Engineering (SE) is a complex and challenging field that incorporates the knowledge of systems engineering processes, the ability to synthesize a wide-range of engineering disciplines, and the ability to lead a team of people to successfully accomplish the goals of a project. It requires hard technical skills and soft-skill leadership savvy. As a result, three main development needs are identified: 1. Knowledge of SE processes, the benefits of these processes to a project and their tailored application 2. Knowledge of a wide-range of engineering disciplines, how they interrelate in a system, and the development of sound technical judgement 3. Team leadership to direct and motivate a team of subsystem and discipline experts This paper describes the establishment of a comprehensive training and development program for Systems Engineers at NASA Ames Research Center that addresses in part each of these three areas from the perspective of the implementing manager. A variety of methods have been utilized including the establishment of a SE Community of Practice, a unique and innovative web tool, on-line videos, classroom training in NASA’s 17 Common Technical Processes, guidance on the tailored application of these processes, monthly technical talks, mentoring in both technical judgment and team leadership, and NASA’s Leadership Development Programs. While much of professional SE development must come through project experience, the approaches listed above can accelerate development. The diversity of skills required of Systems Engineering demands a multi-faceted approach to successfully train and develop this critical skill.

development↗

Mars Technology Program (MTP) Communications and Tracking Technologies for Mars Exploration

The MTP Communications and Tracking Technology Development Program aims to develop critical enabling technology components and products that will make the future high capacity communications links from Mars possible. It comprises ten technology development tasks. This paper briefly describes each task and gives a summary of the current state of the research and future recommendations.

X-band↗

Impact of Structural Defects and Hydronium Ion Concentration on the Stability of Zeolite BEA in Aqueous Phase

The presence of fluoride anions in the synthesis gel leads to zeolite BEA with high hydrothermal stability. This longer lifetime is caused by a lower concentration of internal silanol defects that are sites of the initial framework hydrolysis eventually destroying the lattice structure. The lifetime of these zeolites was the higher the lower the concentration of framework bridging hydroxyl groups that form hydronium ions was. While lattice hydrolysis was initiated at defect sites in all cases, the role of defects became less important as the concentration of hydronium ions increased. At higher concentration of hydrated hydronium ions, the presence of water associated with the hydrated hydronium ions limits the useful lifetime of zeolite catalysts in water. For such materials, the selective hydrophobization of the external surface extends the lifetime. Acknowledgments: S.P. and M.A.D. acknowledge support by the Materials Synthesis and Simulation Across Scales (MS3 Initiative) conducted under Laboratory Directed Research & Development Program at PNNL. H.S. and H.W. were supported by the Chemical Transformation Initiative (CTI) conducted under Laboratory Directed Research & Development Program at PNNL. J.A.L. was supported by the US Department of Energy, Office of Science, Office of Basic Energy Sciences.

Prodinger, Sebastian↗

A theoretical/experimental program to develop active optical pollution sensors, part 2

Progress is reported on experimental investigations of Lidar and the application of Lidar to environmental and atmospheric science. Specifically the following programs are considered: calibration and application of the LaRC 48-inch Lidar; efficient and certain detection of SO2 and other gases in the calibration tank using the Raman Stack Monitor Lidar; the potential of Lidar remote sensing from the space shuttle; and the planning and mounting of efforts to realize the promise of backscatter differential absorption Lidar.

Poultney, S. K.↗

NASA/Goddard Thermal Technology Overview 2014

This presentation summarizes the current plans and efforts at NASA Goddard to develop new thermal control technology for anticipated future missions. It will also address some of the programmatic developments currently underway at NASA, especially with respect to the Technology Development Program at NASA. While funding for basic technology development is still scarce, significant efforts are being made in direct support of flight programs. New technology development continues to be driven by the needs of future missions, and applications of these technologies to current Goddard programs will be addressed. Many of these technologies also have broad applicability to DOD, DOE, and commercial programs. Partnerships have been developed with the Air Force, Navy, and various universities to promote technology development. In addition, technology development activities supported by internal research and development (IRAD) program, the Small Business Innovative Research (SBIR) program, and the NASA Engineering and Safety Center (NESC), are reviewed in this presentation. Specific technologies addressed include; two-phase systems applications and issues on NASA missions, latest developments of electro-hydrodynamically pumped systems, development of high electrical conductivity coatings, and various other research activities. New Technology program underway at NASA, although funding is limited center dot NASA/GSFC's primary mission of science satellite development is healthy and vibrant, although new missions are scarce - now have people on overhead working new missions and proposals center dot Future mission applications promise to be thermally challenging center dot Direct technology funding is still very restricted - Projects are the best source for direct application of technology - SBIR thermal subtopic resurrected in FY 14 - Limited Technology development underway via IRAD, NESC, other sources - Administrator pushing to revive technology and educational programs at NASA - new HQ directorate established

Cooling↗

AUSSAT mobile satellite services

An overview of AUSSAT's planned mobile satellite system is given. The development program which is being undertaken to achieve the 1992 service date is described. Both business and technical aspects of the development program are addressed.

Nowland, Wayne L.↗

DOE Advanced Gas Reactor Fuel Development and Qualification Program Overview

DOE AGR fuel development and qualification program overview to include TRISO fuel development and program elements, AGR timeline, Irradiation test results, performance evaluation results, major accomplishments and milestones over 12 months, and university-led TRISO related research projects.

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗