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At least 937 records · Page 52

Ab initio calculations of three-nucleon scattering

Results on three-nucleon (3N) elastic scattering below the pion production threshold are discussed with an emphasis on the need for a three-nucleon force (3NF). The large discrepancies found between a theory based on numerical solutions of 3N Faddeev equations with (semi)phenomenological NN potentials only and data point to the need for 3NF’s. This notion is supported by the fact that another possible reason for the discrepancies in elastic nucleon-deuteron (Nd) scattering, relativistic effects, turned out to be small. Results for new generation of chiral NN forces (up to N{sup 4}LO) together with theoretical truncation errors are shown.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

Illustrating the Spatiotemporal Complexity of No2 Columns Using A Multi-Perspective Observing System: Moving Toward Geostationary Product Validation and Applications

As a precursor to secondary pollutants like ozone and PM2.5, nitrogen dioxide (NO2) is crucial to understand when addressing air quality issues. However, due to NO2’s short lifetime during the daytime and complexity of emission sources in urbanized regions, interpreting datasets from ground or satellite perspectives alone are challenged by variance in spatial and temporal resolutions. High resolution airborne mapping (< 1 km) of NO2 column densities across morning, midday, and afternoon add a unique perspective toward interpreting satellite data with respect to ground-measurements. This presentation focuses on the interpretation of spatiotemporal complexity of NO2 columns from the Synergistic TEMPO Air Quality Science Study (STAQS). The mission’s goal is to integrate geostationary observations from Tropospheric Emissions: Monitoring of Pollution (TEMPO) with traditional and enhanced air quality monitoring to improve the understanding of air quality science for increased societal benefit. We will demonstrate the interweaved perspective of NO2 columns from ground-based Pandora spectrometers and satellite-based observations (e.g., TROPOMI) as compared to high spatial resolution airborne observations from the GEOstationary Coastal and Air Pollution Events (GEO-CAPE) Airborne Simulator (GCAS). This includes the evaluation of each dataset through comparison to each other to identify potential biases in data products and the impact of heterogeneity on these comparisons. Airborne data will also be used as a proxy for geostationary observations with morning, midday, and afternoon raster maps collected over four cities (Los Angeles, Chicago, Toronto, and New York City). Finally, recent research outcomes will be presented to demonstrate how airborne and geostationary observations can be used to evaluate emission inventories and air quality models.

Laura Judd↗

Applying Machine Learning and Bayesian Inference to Identify and Locate Moving Anthropogenic Sources Using Distributed Acoustic Sensing Data

Distributed acoustic sensing (DAS) systems, which use existing telecommunication fibers, offer high‐resolution capabilities ideal for recording anthropogenic sources. However, the complexity of urban environments and the large amount of data recorded by DAS require automated methods to efficiently detect and categorize anthropogenic sources. Here, we evaluate how well three machine learning models (k‐nearest neighbor [k‐NN], convolutional neural networks, and recurrent‐convolutional neural networks) can identify various anthropogenic sources recorded by DAS. Our findings reveal that both k‐NN and neural network methods perform well in high signal‐to‐noise ratio (SNR) settings. However, their accuracy decreases at SNRs <4. We also use Kalman filtering, a form of Bayesian inference, on backprojected locations of these sources to recover locations that generally fall within standard smartphone Global Positioning System errors. By combining machine learning and Kalman filter results, we calculate a multidimensional model of moving anthropogenic sources. These results demonstrate the potential of DAS data in urban seismology for accurately identifying and locating such sources. Depending on the research objectives, these sources can be further studied or filtered out to improve the quality of seismic data for earthquake studies. Such methods provide a valuable tool for urban seismology and seismic hazard analysis.

Luckie, Thomas William [Sandia National Laboratori↗

Wildfire Segmentation From Remotely Sensed Data Using Quantum-Compatible Conditional Vector Quantized-Variational Autoencoders

Wildfires represent a critical environmental hazard with multifaceted implications for ecosystems, communities, and public health [1]. The escalating frequency and intensity of wildfires globally have intensified the urgency for robust segmentation methodologies to facilitate effective mitigation, response, and recovery strategies [2]. Accurate wildfire segmentation is pivotal for delineating fire boundaries, assessing progression patterns, and prioritizing resource allocation during emergency scenarios. Furthermore, precise segmentation enables stakeholders, including policymakers, environmental scientists, and emergency responders, to formulate evidence-based strategies, thereby minimizing socio-economic disruptions and ecological degradation. Consequently, advancing wildfire segmentation techniques through innovative technological interventions remains a paramount research imperative. Although foundational in wildfire segmentation, traditional deterministic models exhibit inherent limitations that compromise their efficacy in dynamic and uncertain environments. These models often operate on rigid algorithms prioritizing deterministic classifications, thereby overlooking the inherent complexities and uncertainties associated with wildfire behavior and satellite data variability. Such deterministic frameworks tend to produce oversimplified representations that fail to capture the intricate nuances of evolving fire dynamics, spatial heterogeneity, and environmental interactions [1]. Consequently, the deterministic approach’s propensity for uncertainty collapsing [1, 3] hampers the accuracy, reliability, and applicability of segmentation outcomes in real-world scenarios. Contrastingly, stochastic models offer a more nuanced and adaptable framework for wildfire segmentation. By integrating probabilistic elements into the modeling paradigm, stochastic approaches, particularly probabilistic approaches such as variational auto encoders (VAEs) [4], facilitate comprehensive uncertainty assessment, enabling researchers to quantify and incorporate uncertainties into segmentation outcomes effectively. This probabilistic nature empowers stochastic models to encapsulate variability, account for data inconsistencies, and adapt to evolving environmental conditions, enhancing segmentation accuracy, reliability, and robustness. Embracing stochastic methodologies thus catalyzes advancements in wildfire science by fostering a more holistic, adaptive, and resilient segmentation framework. Despite VAEs demonstrating significant promise in various applications, they come with inherent limitations that have garnered attention within the machine learning community. One of the primary drawbacks lies in their reliance on static priors, which essentially assume a fixed distribution for latent variables, thereby limiting the model’s flexibility to capture complex data structures effectively [5]. This static nature leads to suboptimal representations, especially when dealing with complex and high-dimensional data. Additionally, VAEs often struggle with generating sharp and realistic samples, a phenomenon commonly referred to as mode collapse [5, 7, 6]. Furthermore, the optimization process in VAEs, which involves balancing the reconstruction loss and the regularization term, can sometimes be challenging to fine-tune [7]. In recent efforts to address these shortcomings, alternative approaches like Vector Quantized Variational Auto encoders(VQ-VAEs) [7], address the challenges by incorporating discrete latent variables and leveraging techniques that enhance the quality and diversity of generated samples while maintaining efficient training dynamics. VQ-VAEs propose a dynamic prior distribution generation mechanism that diverges from the static priors commonly associated with traditional VAEs. This dynamic approach allows for more adaptive and context-aware latent variable representations, thereby potentially capturing complex data structures more effectively. Unlike autoregressive prior models such as PixelCNN, which, despite their ability to model dependencies across data dimensions, suffer from significant computational inefficiencies and lack flexibility in handling diverse datasets. In our work, we propose to use a generative quantum-compatible approach to help alleviate the shortcomings of autoregressive prior model in VQ-VAEs. Restricted Boltzmann Machines (RBMs) are a viable alternative prior model that can learn prior distributions in a faster and more flexible manner. In this research endeavor, we meticulously curate a state-of-the-art dataset leveraging satellite MODIS data in conjunction with VIIRS fire masks, derived from Fire Radiative Power (FRP), thereby encapsulating diverse wildfire scenarios and environmental contexts. We developed a conditional VQ-VAE architecture with the RBM prior model that is trained in a supervised manner for segmenting wildfire masks. This innovative approach synergistically harnesses deep learning capabilities, enabling the generation of segmentation maps characterized by heightened precision, granularity, and contextual relevance. Furthermore, replacing the autoregressive prior learning method proposed by the original VQ-VAE with a prior density approximation via quantum-compatible RBM facilitates expedited inference processes, augments flexibility in prior sampling, optimizes computational efficiency and establishes a groundbreaking benchmark in wildfire segmentation methodologies.

quantum machine learning↗

CLEAP Project: OR-SAGE Analysis for MT, UT, and CO States

The OR-SAGE tool is designed to use industry-accepted practices in screening sites and then employ the proper array of data sources through the considerable computational capabilities of GIS technology available at ORNL. The tool was developed to screen the potential for NPP siting on a national and regional basis. However, because of the tool granularity, it is often focused specifically on the immediate area around user sites of interest. If data center siting parameters can be added to OR-SAGE, the ability to evaluate data center siting on a localized scale will be beneficial.1 More than 60 data sets have been collected and processed by ORNL to develop exclusionary, avoidance, and suitability criteria for screening sites for a variety of power generation types, including nuclear power plants. Available site evaluation parameters include population density, slope, seismic activity, proximity to cooling-water sources, proximity to hazard facilities, avoidance of protected lands and floodplains, susceptibility to landslide hazards, and many others. All siting parameters should be considered as flags to inform siting decisions and should not be used to rule in or rule out any NPP site. Once data center siting parameters are identified, appropriate data sets will be collected and processed. The OR-SAGE process is very versatile. Essentially, OR-SAGE is a visual, relational database. The database partitions the contiguous United States, a total of 720 million hectares (~1.8 billion acres), into 100-m by 100-m (1 hectare or ~2.5 acre) cells. The database is tracking just under 700 million individual land cells. Successive suitability criterion is applied to each cell in the database. User-specified thresholds can be applied to each siting parameter data layer. In this manner, a variety of scenarios can be quickly and thoroughly evaluated. Data can be added and/or revised within OR-SAGE to address user interests. Siting security assessment capability is currently being added to OR-SAGE. Security is expected to be of concern at data centers whether it is collocated with a nuclear power generating technology or not. If data center is collocated with a nuclear power generating source, the security threat attractiveness level of both will likely increase. It will be of additional benefit if a potential data center site is also assessed for security vulnerability.

97 MATHEMATICS AND COMPUTING↗

OCTS and SeaWiFS Bio-Optical Algorithm and Product Validation and Intercomparison in US Coastal Waters

The successful launch of the National Space Development Agency of Japan (NASDA) Ocean Color and Temperature Sensor (OCTS) in August 1996, and the launch of Orbital Science Corporation's (OSC) Sea-viewing Wide-Field-of-view Sensor (SeaWiFS) in August 1997 signaled the beginning of a new era for ocean color research and application. These data may be used to remotely evaluate 1) water quality, 2) transport of sediments and adhered pollutants, 3) primary production, upon which commercial shellfish and finfish populations depend for food, and 4) harmful algal blooms which pose a threat to public health and economies of affected areas. Several US government agencies have recently expressed interest in monitoring U.S. coastal waters using optical remote sensing. This renewed interest is broadly driven by 1) resource management concerns over the impact of coastward shifts in population and land use on the ecosystems of estuaries, wetlands, nearshore benthic environments and fisheries, 2) recognition of the need to understand short time scale global change due to urbanization of sensitive land-margin ecosystems, and 3) national security issues. Satellite ocean color sensors have the potential to furnish data at the appropriate time and space scales to evaluate and resolve these concerns and problems. In this draft technical memorandum, we outline our progress during the first year of our SIMBIOS project to evaluate ocean color bio-optical algorithms and products generated using OCTS and SeaWiFS data in coastal US waters.

Brown, Christopher W.↗

Elephants Sharing the Highway: Studying TCP Fairness in Large Transfers over High Throughput Links

Escalating bandwidth demand strains high-performance data networks, posing potential performance risks. TCP congestion control algorithms enhance reliability and optimize bandwidth usage. Network performance is influenced by factors such as AQM algorithms and router buffer size. In the context of constrained network resources, understanding how TCP flows share networks and the resulting performance impact is essential. This paper introduces insights into TCP fairness and performance involving a comparison of TCP CUBIC, Reno, Hamilton, and BBR versions 1 and 2 across real-world networks supporting high bandwidths of up to 25 Gbps. The research explores TCP behaviors with AQM algorithms like FIFO, FQ_CODEL, and RED, alongside diverse buffer sizes. Notably, findings reveal that manipulating buffers and queuing methods yields contrasting outcomes based on bandwidth. BBRv2 emerges as a superior fair algorithm, pivotal for swift transfers, particularly in scientific data scenarios. These results provide crucial guidance for future network design, ensuring equitable performance optimization.

Kiran, Mariam↗

A Measurement of the Cosmic Microwave Background Lensing Potential and Power Spectrum from 500 deg 2 of SPTpol Temperature and Polarization Data

In this work, we present a measurement of the cosmic microwave background (CMB) lensing potential using 500 deg$^2$ of 150 GHz data from the SPTpol receiver on the South Pole Telescope. The lensing potential is reconstructed with signal-to-noise per mode greater than unity at lensing multipoles $L \lesssim 250$, using a quadratic estimator on a combination of CMB temperature and polarization maps. We report measurements of the lensing potential power spectrum in the multipole range of $100< L < 2000$ from sets of temperature-only, polarization-only, and minimum-variance estimators. We measure the lensing amplitude by taking the ratio of the measured spectrum to the expected spectrum from the best-fit $\Lambda$CDM model to the $\textit{Planck}$ 2015 TT+lowP+lensing dataset. For the minimum-variance estimator, we find $A_{\rm{MV}} = 0.944 \pm 0.058{\rm (Stat.)}\pm0.025{\rm (Sys.)}$; restricting to only polarization data, we find $A_{\rm{POL}} = 0.906 \pm 0.090 {\rm (Stat.)} \pm 0.040 {\rm (Sys.)}$. Considering statistical uncertainties alone, this is the most precise polarization-only lensing amplitude constraint to date (10.1 $\sigma$), and is more precise than our temperature-only constraint. We perform null tests and consistency checks and find no evidence for significant contamination.

79 ASTRONOMY AND ASTROPHYSICS↗

Advanced data science toolkit for non-data scientists – A user guide

Emerging modern data analytics attracts much attention in materials research and shows great potential for enabling data-driven design. Data populated from the high-throughput CALPHAD approach enables researchers to better understand underlying mechanisms and to facilitate novel hypotheses generation, but the increasing volume of data makes the analysis extremely challenging. Here in this paper, we introduce an easy-to-use, versatile, and open-source data analytics frontend, ASCENDS (Advanced data SCiENce toolkit for Non-Data Scientists), designed with the intent of accelerating data-driven materials research and development. The toolkit is also of value beyond materials science as it can analyze the correlation between input features and target values, train machine learning models, and make predictions from the trained surrogate models of any scientific dataset. Various algorithms implemented in ASCENDS allow users performing quantified correlation analyses and supervised machine learning to explore any datasets of interest without extensive computing and data science background. The detailed usage of ASCENDS is introduced with an example of experimental high-temperature alloy data.

96 KNOWLEDGE MANAGEMENT AND PRESERVATION↗

Assessing the Quality of Molecular Simulations for Vapor–Liquid Equilibria: An Analysis of the TraPPE Database

As molecular modeling and simulation techniques become increasingly important sources of thermophysical property and phase equilibrium data, the ability to assess the robustness of that data becomes more critical. Recently, the use of the compressibility factor (Z) has been suggested as a metric for testing the quality of simulation data for vapor–liquid equilibria (VLE). Int his paper, we analyze predicted VLE data from the transferable potentials for phase equilibria (TraPPE) database and show that, apart from data entry or typographical errors, Z will always be well-behaved in Gibbs ensemble Monte Carlo (GEMC) simulations even when the simulations are not sufficiently equilibrated. However, this is not true for grand canonical Monte Carlo simulations. When the pressure is calculated from the internal forces, then pressure and density are strongly correlated for the vapor phase and, for GEMC simulations, it is recommended to treat Z as an instantaneous mechanical property. From analysis of the TraPPE VLE data, we propose a complementary metric based on the predicted vapor pressures at three neighboring temperatures and their deviation from a local Clausius–Clapeyron fit.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Clustering of noisy image data using an adaptive neuro-fuzzy system

Identification of outliers or noise in a real data set is often quite difficult. A recently developed adaptive fuzzy leader clustering (AFLC) algorithm has been modified to separate the outliers from real data sets while finding the clusters within the data sets. The capability of this modified AFLC algorithm to identify the outliers in a number of real data sets indicates the potential strength of this algorithm in correct classification of noisy real data.

Pemmaraju, Surya↗

Improving Characterization of Miscellaneous Energy Loads in Energy Demand Models

Miscellaneous energy loads (MELs) comprise a significant and growing portion of total building energy consumption. However relatively little is known about the products that make up MELs end uses, and MELs are modeled with less granularity than major end uses in energy demand models such as the U.S. Department of Energy’s Scout energy efficiency impact analysis tool or the U.S. Energy Information Administration’s National Energy Modeling System (NEMS). This paper identifies differences in the way MELs versus major building end uses are modeled, and then reviews potential sources of MELs baseline technology data that could be used to improve their characterization in energy demand models. Case studies of dry distribution transformers, hot water circulation pumps, and Japanese-style automatic bidets are presented to compare and contrast the level of baseline data available for different end uses. We show that there is potential to use data from energy conservation standards and other sources to significantly improve representation of some MELs in energy demand models, while other emerging MELs require further data collection before they can be modeled precisely.

Miscellaneous Electric Loads, MELs, Models, Nation↗

Improving Characterization of Miscellaneous Energy Loads in Energy Demand Models

Miscellaneous energy loads (MELs) comprise a significant and growing portion of total building energy consumption. However relatively little is known about the products that make up MELs end uses, and MELs are modeled with less granularity than major end uses in energy demand models such as the U.S. Department of Energy's Scout energy efficiency impact analysis tool or the U.S. Energy Information Administration's National Energy Modeling System (NEMS). This paper identifies differences in the way MELs versus major building end uses are modeled, and then reviews potential sources of MELs baseline technology data that could be used to improve their characterization in energy demand models. Case studies of dry distribution transformers, hot water circulation pumps, and Japanese-style automatic bidets are presented to compare and contrast the level of baseline data available for different end uses. We show that there is potential to use data from energy conservation standards and other sources to significantly improve representation of some MELs in energy demand models, while other emerging MELs require further data collection before they can be modeled precisely.

Fares, Robert↗

Uranium and strontium fate in waste-weathered sediments: Scaling of molecular processes to predict reactive transport

Objectives of the project: 1. Determine the process coupling that occurs between mineral transformation and contaminant (U and Sr) speciation in acid-uranium waste weathered Hanford sediments. 2. Establish linkages between molecular-scale contaminant speciation and meso-scale contaminant lability, release and reactive transport. 3. Make conjunctive use of molecular- to bench-scale data to constrain the development of a mechanistic, reactive transport model that includes coupling of contaminant sorption-desorption and mineral transformation reactions. Hypotheses tested: - Uranium and strontium speciation in legacy sediments from the U-8 and U-12 Crib sites can be reproduced in bench-scale weathering experiments conducted on unimpacted Hanford sediments from the same formations. - Reactive transport modeling of future uranium and strontium releases from the vadose zone of acid-waste weathered sediments can be effectively constrained by combining molecular-scale information on contaminant bonding environment with grain-scale information on contaminant phase partitioning, and meso-scale kinetic data on contaminant release from the waste-weathered porous media. - Although field contamination and laboratory experiments differ in their diagenetic time scales (decades for field vs. months to years for lab), sediment dissolution, neophase nucleation, and crystal growth reactions that occur during the initial disequilibrium induced by waste-sediment interaction leave a strong imprint that persists over subsequent longer-term equilibration time scales and, therefore, give rise to long-term memory effects. Enabling capabilities developed: Our team developed an iterative measure-model approach that is broadly applicable to elucidate the mechanistic underpinnings of reactive contaminant transport in geomedia subject to active weathering. Experimental design: Hypotheses were tested by comparing (with a similar set of techniques) the geochemical transformations and transport behaviors that occured in bench-scale studies of waste-sediment interaction with parallel model systems studies of homogeneous nucleation and neo-phase dissolution. Initial plans were to compare results with core sample extractions from the acid uranium waste impacted U-8 and U-12 Cribs at Hanford (see original proposal and letter of collaboration from J. Zachara). However, this part of the project was impossible because funding for core extractions were eliminated from the DoE budget. Three distinct crib waste aqueous simulants (whose composition is based on the most up-to-date information from field site investigations) were reacted with Hanford sediments in batch and column systems. Coupling of contaminant uptake to mineral weathering was monitored using a suite of methods both during waste-sediment interaction, and after, when waste-weathered sediments were subjected to infusion with circumneutral background pore water solutions. Our research was designed to adapt as needed to maintain a strong dialogue between laboratory and modeling investigations so that model development was increasingly constrained by emergent data and understanding. Potential impact of the project to DOE: Better prediction of contaminant uranium transport was achieved by employing multi-faceted lines of inquiry to build a strong bridge between molecular- and field-scale information. By focusing multiple lines and scales of observation on a common experimental design, our collaborative team revealed non-linear and emergent behavior in contaminated weathering systems. A goal of the current project was to expand our modeling capabilities, originally focused on hyperalkaline legacy waste streams, to include acidic weathering reactions that, as described above, were expected to result in profoundly different products. We were able to achieve this goal, and showed that these products nonetheless undergo analogous silicate and non-silicate transformation, ripening and aging processes. Our prediction that these weathering reactions would vary with waste stimulant chemistry resulted in data that was incorporated directly into a reactive transport model structure.

54 ENVIRONMENTAL SCIENCES↗

The nightward ion flow scenario at Venus revisited

We indicate how existing Pioneer Venus Orbiter (PVO) data might be used to gain a better understanding of nightward ion flow in the Venusian ionosphere. Calculations based on PVO measurements made at solar maximum suggest that the global nightward flow of O(+) may be signifcantly greater than is required to maintain the observed nightside ionosphere densities. The validity of this conclusion depends upon (1) the accuracy with which the flow can be determined from the PVO ion density and velocity measurements and (2) the validity of the ionosphere theory used to estimate the required downward O(+) flux on the night side. If the measurements and theory are assumed to be accurate, the excess nightward flow implies a significant rate of ion escape from the planet, particularly at times of low solar wind dynamic pressure, Psw, when the ionopause rises to allow increased nightward flow. To illustrate a potentially important mechanism for ion escape from Venus, we present Orbiter Electron Temperature Probe (OETP) observations of plasma clouds and scavenged ionospheric plasma observed above the ionopause. We then employ OETP and Orbiter Retarding Potential Analyzer (ORPA) data to reexamine the global ion flow for average Psw conditions.

Brace, L. H.↗

THE DUST SUBLIMATION RADIUS AS AN OUTER ENVELOPE TO THE BULK OF THE NARROW Fe Kα LINE EMISSION IN TYPE 1 AGNs

The Fe Kα emission line is the most ubiquitous feature in the X-ray spectra of active galactic nuclei (AGNs), but the origin of its narrow core remains uncertain. Here, we investigate the connection between the sizes of the Fe Kα core emission regions and the measured sizes of the dusty tori in 13 local Type 1 AGNs. The observed Fe Kα emission radii (R{sub Fe}) are determined from spectrally resolved line widths in X-ray grating spectra, and the dust sublimation radii (R{sub dust}) are measured either from optical/near-infrared (NIR) reverberation time lags or from resolved NIR interferometric data. This direct comparison shows, on an object-by-object basis, that the dust sublimation radius forms an outer envelope to the bulk of the Fe Kα emission. R{sub Fe} matches R{sub dust} well in the AGNs, with the best constrained line widths currently. In a significant fraction of objects without a clear narrow line core, R{sub Fe} is similar to, or smaller than, the radius of the optical broad line region. These facts place important constraints on the torus geometries for our sample. Extended tori in which the solid angle of fluorescing gas peaks at well beyond the dust sublimation radius can be ruled out. We also test for luminosity scalings of R{sub Fe}, finding that the Eddington ratio is not a prime driver in determining the line location in our sample. We also discuss in detail potential caveats of data analysis and instrumental limitations, simplistic line modeling, uncertain black hole masses, and sample selection, showing that none of these is likely to bias our core result. The calorimeter on board Astro-H will soon vastly increase the parameter space over which line measurements can be made, overcoming many of these limitations.

79 ASTRONOMY AND ASTROPHYSICS↗

Computing the ankle-brachial index with parallel computational fluid dynamics

The ankle-brachial index (ABI), a ratio of arterial blood pressure in the ankles and upper arms, is used to diagnose and monitor circulatory conditions such as coarctation of the aorta and peripheral artery disease. Computational simulations of the ABI can potentially determine the parameters that produce an ABI indicative of ischemia or other abnormalities in blood flow. However, 0- and 1-D computational methods are limited in describing a 3-D patient-derived geometry. Thus, we present a massively parallel framework for computational fluid dynamics (CFD) simulations in the full arterial system. Additionally, using the lattice Boltzmann method to solve the Navier–Stokes equations, we employ highly parallelized and scalable methods to generate the simulation domain and efficiently distribute the computational load among processors. For the first time, we compute an ABI with 3-D CFD. In this proof-of-concept study, we investigate the dependence of ABI on the presence of stenoses, or narrowed regions of the arteries, by directly modifying the arterial geometry. As a result, our framework enables the computation a hemodynamic factor characterizing flow at the scale of the full arterial system, in a manner that is extensible to patient-specific imaging data and holds potential for treatment planning.

59 BASIC BIOLOGICAL SCIENCES↗

A Step-Down Test Procedure for Wavelet Shrinkage Using Bootstrapping

Wavelet thresholding (or shrinkage) attempts to remove the noises existing in the signals while preserving inherent pattern characteristics in the reconstruction of true signals. For data-denoising purpose, we present a new wavelet thresholding procedure which employs the step-down testing idea of identifying active contrasts in unreplicated fractional factorial experiments. The proposed method employs bootstrapping methods to a step-down test for thresholding wavelet coefficients. By introducing the concept of a false discovery error rate in testing wavelet coefficients, we shrink the wavelet coefficients with p -values higher than the error rate. The error rate controls the expected proportion of wrongly accepted coefficients among chosen wavelet coefficients. Bootstrap samples are used to approximate the p -value for computational efficiency. We also present some guidelines for selecting the values of hyper-parameters which affect the performance in the step-down thresholding procedure. Based on some common testing signals and an air-conditioner sounds example, the comparison of our proposed procedure with other thresholding methods in the literature is performed. The analytical results show that the proposed procedure has a potential in data-denoising and data-reduction in a variety of signal reconstruction applications.

42 ENGINEERING↗