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At least 991 records · Page 55

Flood and Landslide Applications of High Time Resolution Satellite Rain Products

Experimental, potentially real-time systems to detect floods and landslides related to heavy rain events are described. A key basis for these applications is high time resolution satellite rainfall analyses. Rainfall is the primary cause for devastating floods across the world. However, in many countries, satellite-based precipitation estimation may be the best source of rainfall data due to insufficient ground networks and absence of data sharing along many trans-boundary river basins. Remotely sensed precipitation from the NASA's TRMM Multi-satellite Precipitation Analysis (TMPA) operational system (near real-time precipitation at a spatial-temporal resolution of 3 hours and 0.25deg x 0.25deg) is used to monitor extreme precipitation events. Then these data are ingested into a macro-scale hydrological model which is parameterized using spatially distributed elevation, soil and land cover datasets available globally from satellite remote sensing. Preliminary flood results appear reasonable in terms of location and frequency of events, with implementation on a quasi-global basis underway. With the availability of satellite rainfall analyses at fine time resolution, it has also become possible to assess landslide risk on a near-global basis. Early results show that landslide occurrence is closely associated with the spatial patterns and temporal distribution of TRMM rainfall characteristics. Particularly, the number of landslides triggered by rainfall is related to rainfall climatology, antecedent rainfall accumulation, and intensity-duration of rainstorms. For the purpose of prediction, an empirical TMPA-based rainfall intensity-duration threshold is developed and shown to have skill in determining potential areas of landslides. These experimental findings, in combination with landslide surface susceptibility information based on satellite-based land surface information, form a starting point towards a potential operational landslide monitoring/warning system around the globe.

Adler, Robert F.↗

Assessment of drug-induced arrhythmic risk using limit cycle and autocorrelation analysis of human iPSC-cardiomyocyte contractility

Cardiac safety assays incorporating label-free detection of human stem-cell derived cardiomyocyte contractility provide human relevance and medium throughput screening to assess compound-induced cardiotoxicity. In an effort to provide quantitative analysis of the large kinetic datasets resulting from these real-time studies, we applied bioinformatic approaches based on nonlinear dynamical system analysis, including limit cycle analysis and autocorrelation function, to systematically assess beat irregularity. The algorithms were integrated into a software program to seamlessly generate results for 96-well impedance-based data. Our approach was validated by analyzing dose- and time-dependent changes in beat patterns induced by known proarrhythmic compounds and screening a cardiotoxicity library to rank order compounds based on their proarrhythmic potential. We demonstrate a strong correlation for dose-dependent beat irregularity monitored by electrical impedance and quantified by autocorrelation analysis to traditional manual patch clamp potency values for hERG blockers. In addition, our platform identifies non-hERG blockers known to cause clinical arrhythmia. Our method provides a novel suite of medium-throughput quantitative tools for assessing compound effects on cardiac contractility and predicting compounds with potential proarrhythmia and may be applied to in vitro paradigms for pre-clinical cardiac safety evaluation. - Highlights: • Impedance-based monitoring of human iPSC-derived cardiomyocyte contractility • Limit cycle analysis of impedance data identifies aberrant oscillation patterns. • Nonlinear autocorrelation function quantifies beat irregularity. • Identification of hERG and non-hERG inhibitors with known risk of arrhythmia • Automated software processes limit cycle and autocorrelation analyses of 96w data.

60 APPLIED LIFE SCIENCES↗

National Security Programs - Cyber: MMAREJBLIGE – Modular Multi Agent Grid Emulation for Joined Breakdowns in Linked Generative Emulations - 23-0644

Modular Multi Agent Grid Emulations for Joined Breakdowns in Linked Generative Emulations (MMAREJBLIGE) introduces an agent-based modeling framework into real-time cyber-physical emulation to achieve a context-aware environment that introduces operator/attacker/external-condition variability to improve emulation fidelity and testing rigor. We detail our agent framework design, internal communication via message passing, and time synchronization, as well as the individual components of the system. We include a brief analysis of several scenarios run on a real-time, hardware-in-the-loop, Industrial Control Systems (ICS) test-bed which include normal operation, physical disruption, disruption with mitigation, and disruption with mitigation during a cyber denial-of-service (DOS) attack.

42 ENGINEERING↗

Real-time measurement of sodium chloride in individual aerosol particles by mass spectrometry

The method of particle analysis by mass spectrometry has been applied to the quantitative measurement of sodium chloride in individual particles on a real-time basis. Particles of known masses are individually introduced, in the form of a beam, into a miniature Knudsen cell oven (1600 K). The oven is fabricated from rhenium metal sheet (0.018 mm thick) and is situated in the ion source of a quadrupole mass spectrometer. A particle once inside the oven is trapped and completely volatilized; this overcomes the problem of partial volatilization due to particles bouncing from the filament surface. Individual particles are thermally volatilized and ionized inside the rhenium oven, and produce discrete sodium ion pulses whose intensities are measured with the quadrupole mass spectrometer. An ion pulse width of several milliseconds (4-12 ms) is found for particles in the mass range 1.3 x 10 to the -13th to 5.4 x 10 to the -11th g. The sodium ion intensity is found to be proportional to the particle mass to the 0.86-power. The intensity distribution for monodisperse aerosol particles possesses a geometric standard deviation of 1.09, showing that the method can be used for the determination of the mass distribution function with good resolution in a polydisperse aerosol.

Sinha, M. P.↗

Measurement of Irradiated Pyroprocessing Samples via Laser Induced Breakdown Spectroscopy

The primary objective of this research is to develop an applied technology and provide an assessment to remotely measure and analyze the real time or near real time concentrations of used nuclear fuel (UNF) dissolute in electrorefiners. Here, Laser-Induced Breakdown Spectroscopy (LIBS), in UNF pyroprocessing facilities will be investigated. LIBS is an elemental analysis method, which is based on the emission from plasma generated by focusing a laser beam into the medium. This technology has been reported to be applicable in the media of solids, liquids (includes molten metals), and gases for detecting elements of special nuclear materials. The advantages of applying the technology for pyroprocessing facilities are: (i) Rapid real-time elemental analysis|one measurement/laser pulse, or average spectra from multiple laser pulses for greater accuracy in < 2 minutes; (ii) Direct detection of elements and impurities in the system with low detection limits|element specific, ranging from 2-1000 ppm for most elements; and (iii) Near non-destructive elemental analysis method (about 1 g material). One important challenge to overcome is achieving high-resolution spectral analysis to quantitatively analyze all important fission products and actinides. Another important challenge is related to accessibility of molten salt, which is heated in a heavily insulated, remotely operated furnace in a high radiation environment with an argon atmosphere.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

In Situ TEM Multi-Beam Ion Irradiation as a Technique for Elucidating Synergistic Radiation Effects

Materials designed for nuclear reactors undergo microstructural changes resulting from a combination of several environmental factors, including neutron irradiation damage, gas accumulation and elevated temperatures. Typical ion beam irradiation experiments designed for simulating a neutron irradiation environment involve irradiating the sample with a single ion beam and subsequent characterization of the resulting microstructure, often by transmission electron microscopy (TEM). This method does not allow for examination of microstructural effects due to simultaneous gas accumulation and displacement cascade damage, which occurs in a reactor. Sandia’s in situ ion irradiation TEM (I3TEM) offers the unique ability to observe microstructural changes due to irradiation damage caused by concurrent multi-beam ion irradiation in real time. This allows for time-dependent microstructure analysis. A plethora of additional in situ stages can be coupled with these experiments, e.g., for more accurately simulating defect kinetics at elevated reactor temperatures. This work outlines experiments showing synergistic effects in Au using in situ ion irradiation with various combinations of helium, deuterium and Au ions, as well as some initial work on materials utilized in tritium-producing burnable absorber rods (TPBARs): zirconium alloys and LiAlO2.

Taylor, Caitlin↗

BoxScore - A real-time beam-diagnosis program for the CAEN digitizer x730 series

BoxScore is a real-time beam diagnosis and monitoring program for the CAEN x730 series digitizer, developed for the ATLAS in-flight system at Argonne National Laboratory. The CAEN x730 series digitizer, with built-in Digital Pulse Processing for the Pulse-Height-Analysis, digitizes the input signal in real-time and processes it using a trapezoidal filter. BoxScore reads the digitizer’s buffer directly, builds and saves events to local files, plots histograms for particle identification, and outputs the rates of selected isotopes every second. Implementation of BoxScore has shortened the time needed for in-flight beam-tuning and has potential applications for other nuclear physics experiments.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Analysis of Fringe Field Formed Inside LDA Measurement Volume Using Compact Two Hololens Imaging Systems

We have designed and fabricated four LDA optical setups consisting of aberration compensated four different compact two hololens imaging systems. We have experimentally investigated and realized a hololens recording geometry which is interferogram of converging spherical wavefront with mutually coherent planar wavefront. Proposed real time monitoring and actual fringe field analysis techniques allow complete characterizations of fringes formed at measurement volume and permit to evaluate beam quality, alignment and fringe uniformity with greater precision. After experimentally analyzing the fringes formed at measurement volume by all four imaging systems, it is found that fringes obtained using compact two hololens imaging systems get improved both qualitatively and quantitatively compared to that obtained using conventional imaging system. Results indicate qualitative improvement of non-uniformity in fringe thickness and micro intensity variations perpendicular to the fringes, and quantitative improvement of 39.25% in overall average normalized standard deviations of fringe width formed by compact two hololens imaging systems compare to that of conventional imaging system.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

Ramp time synchronization

A new method of intercontinental clock synchronization has been developed and proposed for possible use by NASA's Deep Space Network (DSN), using a two-way/three-way radio link with a spacecraft. Analysis of preliminary data indicates that the real-time method has an uncertainty of 0.6 microsec, and it is very likely that further work will decrease the uncertainty. Also, the method is compatible with a variety of nonreal-time analysis techniques, which may reduce the uncertainty down to the tens of nanosecond range.

Hietzke, W.↗

PvaPy streaming framework for real-time data processing

User facility upgrades, new measurement techniques, advances in data analysis algorithms as well as advances in detector capabilities result in an increasing amount of data collected at X-ray beamlines. Some of these data must be analyzed and reconstructed on demand to help execute experiments dynamically and modify them in real time. In turn, this requires a computing framework for real-time processing capable of moving data quickly from the detector to local or remote computing resources, processing data, and returning results to users. In this paper, we discuss the streaming framework built on top of PvaPy, a Python API for the EPICS pvAccess protocol. We describe the framework architecture and capabilities, and discuss scientific use cases and applications that benefit from streaming workflows implemented on top of this framework. We also illustrate the framework's performance in terms of achievable data-processing rates for various detector image sizes.

EPICS pvAccess↗

Scientific & Intelligence Exascale Visualization Analysis System

SIEVAS provides an immersive visualization framework for connecting multiple systems in real time for data science. SIEVAS provides the ability to connect multiple COTS and GOTS products in a seamless fashion for data fusion, data analysis, and viewing. It provides this capability by using a combination of micro services, real time messaging, and web service compliant back-end system.

Money, JamesH.↗

Scientific & Intelligence Exascale Visualization Analysis System

SIEVAS provides an immersive visualization framework for connecting multiple systems in real time for data science. SIEVAS provides the ability to connect multiple COTS and GOTS products in a seamless fashion for data fusion, data analysis, and viewing. It provides this capability by using a combination of micro services, real time messaging, and web service compliant back-end system.

Money, James H.↗

A Wearable Microfluidic Sensing Patch for Dynamic Sweat Secretion Analysis

Wearable sweat sensing is a rapidly rising research area driven by its promising potential in health, fitness, and diagnostic applications. Despite the growth in the field, major challenges in relation to sweat metrics remain to be addressed. These challenges include sweat rate monitoring for its complex relation with sweat compositions and sweat sampling for sweat dynamics studies. Here, we present a flexible microfluidic sweat sensing patch that enhances real-time electrochemical sensing and sweat rate analysis via sweat sampling. The device contains a spiral-patterned microfluidic component that is embedded with ion-selective sensors and an electrical impedance-based sweat rate sensor on a flexible plastic substrate. The patch is enabled to autonomously perform sweat analysis by interfacing the sensing component with a printed circuit board that is capable of on-site signal conditioning, analysis, and transmission. Progressive sweat flow in the microfluidic device, governed by the pressure induced by the secreted sweat, enhances sweat sampling and electrochemical detection via a defined sweat collection chamber and a directed sweat route. The characteristic of the sweat rate sensor is validated through a theoretical simulation, and the precision and accuracy of the flow rate is verified with a commercial syringe pump and a Macroduct sweat collector. On-body simultaneous monitoring of ion (H + , Na + , K + , Cl – ) concentration and sweat rate is also demonstrated for sensor functionality. This sweat sensing patch provides an integrated platform for a comprehensive sweat secretion analysis and facilitates physiological and clinical investigations by closely monitoring interrelated sweat parameters.

47 OTHER INSTRUMENTATION↗

ROLM computers in the flight testing of the Fokker F29 aircraft

The design, development, installation, and operation of the test equipment (MRVS) is discussed. The main feature of the MRVS is continuous recording on an instrumentation recorder data of up to 1500 parameters with a total sample rate of up to 10,000 samples per second. In order to compress the evaluation and calibration time period, the following additional requirements were set for two test systems: (1) recording of selected parameters, time tagged on computer compatible tape (CCT); (2) recording of selected high bandwidth signals and ad hoc parameters on analog tape; (3) onboard presentation of calibrated parameter data, in engineering units, in numerical as well as graphical form for: system checkout during pre-, in- and post-flight, and quick look analysis during in-flight; (4) real time presentation on the ground by telemetry for: flight monitoring, takeoff and landing measurements, and noise measurements; and (5) data processing on the ground on the Fokker-NLR computer network.

Manders, P. J.↗

Enabling discovery data science through cross-facility workflows

Experimental and observational instruments for scientific research (such as light sources, genome sequencers, accelerators, telescopes and electron microscopes) increasingly require High Performance Computing (HPC) scale capabilities for data analysis and workflow processing. Next-generation instruments are being deployed with higher resolutions and faster data capture rates, creating a big data crunch that cannot be handled by modest institutional computing resources. Often these big data analysis pipelines also require near real-time computing and have higher resilience requirements than the simulation and modeling workloads more traditionally seen at HPC centers. While some facilities have enabled workflows to run at a single HPC facility, there is a growing need to integrate capabilities across HPC facilities to enable cross-facility workflows, either to provide resilience to an experiment, increase analysis throughput capabilities, or to better match a workflow to a particular architecture. In this paper we describe the barriers to executing complex data analysis workflows across HPC facilities and propose an architectural design pattern for enabling scientific discovery using cross-facility workflows that includes orchestration services, application programming interfaces (APIs), data access and co-scheduling.

Antypas, Katerina B.↗

Array-Pattern-Match Compiler for Opportunistic Data Analysis

A computer program has been written to facilitate real-time sifting of scientific data as they are acquired to find data patterns deemed to warrant further analysis. The patterns in question are of a type denoted array patterns, which are specified by nested parenthetical expressions. [One example of an array pattern is ((>3) 0 (not=1)): this pattern matches a vector of at least three elements, the first of which exceeds 3, the second of which is 0, and the third of which does not equal 1.] This program accepts a high-level description of a static array pattern and compiles a highly optimal and compact other program to determine whether any given instance of any data array matches that pattern. The compiler implemented by this program is independent of the target language, so that as new languages are used to write code that processes scientific data, they can easily be adapted to this compiler. This program runs on a variety of different computing platforms. It must be run in conjunction with any one of a number of Lisp compilers that are available commercially or as shareware.

James, Mark↗

Latency Analysis of the Nexus Digital Twin Framework

Real-time digital catalogs are increasingly relied upon to track metadata and connect disparate data sources for cloud-based data integration efforts. One such tool, Deeplynx Nexus is supporting real-time digital twin efforts through event-driven data integration and time-series queries. Nexus’s usefulness for these applications depends critically on how quickly individual records can be uploaded and downloaded, since delays directly affect the responsiveness of any system built on top of it. However, the actual latency a user should expect from Nexus has not been systematically measured before, particularly for the small, frequent transactions typical of live sensor feeds. Here we show that single-record round-trip latency is 61.1 ms on a local Nexus instance and 391.7 ms on the hosted production infrastructure, a roughly 6.4x difference driven primarily by fixed per-request overhead rather than data volume. This overhead dominates at small scale: comparing single-record and ten-record trials suggests approximately 56 ms of each single-record request is fixed connection and authentication cost rather than data-transfer time, meaning batching even a handful of records is substantially more efficient than transmitting them individually. At large batch sizes, this pattern reverses for uploads, which converge to near parity between local and hosted environments by 25,000-50,000 records, while download latency remains persistently 5.7-6.4x slower on hosted infrastructure even at scale. These results suggest that Nexus deployments intended for real-time digital twin applications should prioritize record batching over single-record transactions, and that download-path optimization on hosted infrastructure offers the largest remaining opportunity to reduce latency at scale. We anticipate these baseline measurements will serve as a reference point for future digital twin projects evaluating whether Nexus’s latency profile meets their real-time requirements, and as a benchmark for tracking the effect of future infrastructure or API changes.

99 - GENERAL AND MISCELLANEOUS↗

Maturation of Structural Health Management Systems for Solid Rocket Motors

Concepts of an autonomous and automated space-compliant diagnostic system were developed for conditioned-based maintenance (CBM) of rocket motors for space exploration vehicles. The diagnostic system will provide real-time information on the integrity of critical structures on launch vehicles, improve their performance, and greatly increase crew safety while decreasing inspection costs. Using the SMART Layer technology as a basis, detailed procedures and calibration techniques for implementation of the diagnostic system were developed. The diagnostic system is a distributed system, which consists of a sensor network, local data loggers, and a host central processor. The system detects external impact to the structure. The major functions of the system include an estimate of impact location, estimate of impact force at impacted location, and estimate of the structure damage at impacted location. This system consists of a large-area sensor network, dedicated multiple local data loggers with signal processing and data analysis software to allow for real-time, in situ monitoring, and longterm tracking of structural integrity of solid rocket motors. Specifically, the system could provide easy installation of large sensor networks, onboard operation under harsh environments and loading, inspection of inaccessible areas without disassembly, detection of impact events and impact damage in real-time, and monitoring of a large area with local data processing to reduce wiring.

Quing, Xinlin↗