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At least 1,009 records · Page 56
All sourcesNASA NTRSDOE OSTI
NASA NTRS1997

Vertebrate development in the environment of space: models, mechanisms, and use of the medaka

With the advent of space travel, it is of immediate interest and importance to study the effects of exposure to various aspects of the altered environment of space, including microgravity, on Earth-based life forms. Initial studies of space travel have focused primarily on the short-term effects of radiation and microgravity on adult organisms. However, with the potential for increased lengths of time in space, it is critical to now address the effects of space on all phases of an organism's life cycle, from embryogenesis to post-natal development to reproduction. It is already possible for certain species to undergo multiple generations within the confines of the Mir Space Station. The possibility now exists for scientists to consider the consequences of even potentially subtle defects in development through multiple phases of an organism's life cycle, or even through multiple generations. In this discussion, we highlight a few of the salient observations on the effects of the space environment on vertebrate development and reproductive function. We discuss some of the many unanswered questions, in particular, in the context of the choice of appropriate models in which to address these questions, as well as an assessment of the availability of hardware already existing or under development which would be useful in addressing these questions.

Flight Experiment↗
NASA NTRS2013

A Technology Development Roadmap for a Near-Term Probe-Class X-ray Astrophysics Mission

This document presents a roadmap, including proposed budget and schedule, for maturing the instrumentation needed for an X-ray astrophysics Probe-class mission. The Physics of the Cosmos (PCOS) Program Office was directed to create this roadmap following the December 2012 NASA Astrophysics Implementation Plan (AIP). Definition of this mission is called for in the AIP, with the possibility of selection in 2015 for a start in 2017. The overall mission capabilities and instrument performance requirements were defined in the 2010 Astronomy and Astrophysics Decadal Survey report, New Worlds, New Horizons in Astronomy and Astrophysics (NWNH), in connection with the highly ranked International X-ray Observatory (IXO). In NWNH, recommendations were provided regarding the size of, and instrumentation needed by, the next large X-ray observatory. Specifically, the key instrumental capability would be an X-ray calorimeter spectrometer at the focus of a large mirror with angular resolution of 10 arc seconds (arcsec) or better. If possible, a grating spectrometer should also be incorporated into the instrument complement. In response to these recommendations, four instrumentation technologies are included in this roadmap. Three of these are critical for an X-ray mission designed to address NWNH questions: segmented X-ray mirrors, transition edge sensor calorimeters, and gratings. Two approaches are described for gratings, which represent the least mature technology and thus most in need of a parallel path for risk reduction. Also, while current CCD detectors would likely meet the mission needs for grating spectrum readout, specific improvements are included as an additional approach for achieving the grating system effective area requirement. The technical steps needed for these technologies to attain technology readiness levels (TRL) of 5 and 6 are described, as well as desirable modest risk reduction steps beyond TRL-6. All of the technology development efforts are currently funded through the NASA Physics of the Cosmos (PCOS) Strategic Astrophysics Technology (SAT) program; some through the end of FY13, others though FY14. These technology needs are those identified as critical for a near-term mission and briefly described in the 2012 NASA X-ray Mission Concepts Study. This Technology Development Roadmap (TDR) provides a more complete description of each, updates the status, and describes the steps to mature them. For each technology, a roadmap is presented for attaining TRL-6 by 2020 at the latest, and 2018 for most. The funding required for each technology to attain TRL-5 and TRL-6 is presented and justified through a description of the steps needing completion. The total funding required for these technologies to reach TRL-6 is relatively modest, and is consistent with the planned PCOS SAT funding over the next several years. The approximate annual cost through 2018 is $8M. The total cost for all technologies to be matured is $62M (including funding already awarded for FY13 and FY14). This can be contrasted to the $180M recommended by NWNH for technology development for IXO, primarily for the maturation of the mirror technology. The technology described in Section 3 of this document is exclusively that needed for a near-term Probe-class mission, to start in 2017, or for a mission that can be recommended by the next Decadal survey committee for an immediate start. It is important to note that there are other critical X-ray instrumentation technologies under development that are less mature than the ones discussed here, but are essential for a major X-ray mission that might start in the late 2020s. These technologies, described briefly in Section 4, are more appropriately funded through the Astronomy and Physics Research and Analysis (APRA) program.

Development↗
NASA NTRS2020

Georgia Energy III Project Summary - Identifying Habitat and Solar Site Conflict in Georgia by Developing an Environmental Sensitivity Public Mapping Too

The rapid expansion of the solar industry across the state of Georgia has a detrimental effect on the habitats of keystone and threatened species, such as the gopher tortoise (Gopherus polyphemus) and the American black bear (Ursus americanus). NASA DEVELOP collaborated with the Georgia Chapter of The Nature Conservancy (TNC) and the Georgia Department of Natural Resources to continue the research from two previous NASA DEVELOP projects in 2017. The team worked to assess the conflict between solar suitability and environmentally sensitive areas with the Land-Use Conflict Identification Strategy (LUCIS) and to determine how conflict has changed since the 2017 analysis. The project utilized Terra/Aqua Clouds and the Earth's Radiant Energy System (CERES) satellite data and other ancillary datasets to conduct and compare a general statewide LUCIS analysis from 2017 to 2019 and to complete an in-depth LUCIS analysis of Georgia’s fastest-growing solar counties—Taylor, Twiggs, Decatur, and Brooks. The analysis indicated that between 2017 and 2019, the entire state saw high conflict areas increase by 38%. Project partners will use these findings to target areas for promotion of conservation policy and education efforts. The team also provided the TNC with a publicly available web application, called the Environmental Sensitivity Mapping Tool (ESMT), that can be updated as new data are released. The ESMT will be used to educate interest groups, such as solar developers and conservationists, to help them recognize and mitigate the negative effects of solar development on the environment.

DEVELOP Project Summary↗
NASA NTRSDate not supplied

Process Development for Printing Copper Conductible Ink on Flexible Substrates Using Aerosol Jet Technology

Rise in demand for wearable consumer electronics products has given an impetus to the development of flexible electronics technology encompassing flexible substrates and compatible circuitry. Also, additive manufacturing of flexible electronics is emerging rapidly via several techniques such as Inkjet and Aerosol Jet Printing (AJP). The basic component of all flexible circuits to be printed by these technologies is conductible ink, which is generally silver ink. Few studies exist on the printing of copper conductible ink and not many copper ink formulations are available in the market as that of silver inks. This study aims to develop a process development study for deposition of copper conductible lines on flexible substrates using the aerosol jet printing technology. The process development study includes investigation of photosintering parameters for obtaining desirable electrical resistance and shear load to failure values for the printed line. Different pre-drying techniques such as oven pre-drying and platen pre-drying have been used for improving the electrical and mechanical properties of the conductive traces. Techniques such as optical microscopy and white light interferometry have been used for the characterization of print quality of the conductible lines.

printed electronics↗
NASA NTRSDate not supplied

Synthetic Hyperspectral Data for Global Water Quality Algorithm Development

Eutrophication and increasing prevalence of potentially toxic algal blooms (cyanoHABs) among global inland water bodies have become a major ecological concern and require direct attention. There is now a growing necessity to develop pragmatic approaches that allow timely and effective extrapolation of local aquatic processes, to spatially resolved global products. Planned aquatic biogeochemistry remote sensing data products from hyperspectral imagers such as NASA’s Surface Biology and Geology (SBG) mission and relevant aquatic sensor sensitivity precursor airborne imaging spectrometer data provide unprecedented radiometric resolution and sensor sensitivity for characterizing complex aquatic ecosystems. However, scarcity of high-quality freshwater in-situ optical data hinders our capability to develop and validate robust retrieval algorithms. A state-of-the-art synthetic dataset of paired top-of-atmosphere, bottom-of-atmosphere, and optical and biogeophysical data was developed through radiative transfer modeling to simulate natural freshwater ecosystems. A synthetic or precursor dataset for SBG is being used to train robust machine learning models to derive water quality products pertinent to SBG mission objectives. The dataset is also used to show the potential of performing vigorous aquatic sensitivity studies and explored pathways for how best to optimize hyperspectral data for machine learning development. A processing pipeline and resultant global synthetic/precursor dataset for inland waters is presented to establish the innovation for water quality studies of inland waters globally. Optical Society of America Imaging and Applied Optics Congress, Hyperspectral Imaging and Sounding of the Environment (OSA HISE) Meeting, 19-23 July 2021, Virtual Meeting, https://www.osa.org/enus/meetings/osa_meetings/optical_sensors_and_sensing_congress/program/hyperspectral_imaging_and_sounding_of_the_environm/

Synthetic↗
NASA NTRSDate not supplied

Maize Rough Endosperm6 (rgh6) Encodes A Predicted Dead-Box RNA Helicase and Affects Mirna Processing in Endosperm Development

Maize rough endosperm (rgh) mutants have defective kernels with a rough, etched, or pitted endosperm surface. Molecular genetic analysis of this mutant class has identified multiple RNA processing proteins critical to endosperm development. Here, we report on the developmental and molecular function of the rgh6 locus. The rgh6 mutant was isolated from the UniformMu transposon tagging population. Mutant kernels have reduced endosperm size and defective embryos that develop in a more apical position than typical for defective embryos. TB translocation crosses revealed that rgh6 mutant endosperm inhibits normal embryo development. Positional cloning of the rgh6 locus found that it encodes a predicted DEAD-box RNA helicase. Consistent with a predicted function for RNA processing, transient expression of a RGH6-GFP fusion protein is localized to nucleolus and nuclear speckles in Nicotiana benthamiana leaves. Rgh6 transcripts are highly expressed in endosperm epidermal cell types such as the aleurone, basal endosperm cell layer, embryo surrounding region, and endosperm adjacent to scutellum. Markers of these cell types show increased levels in rgh6 mutant kernels. Mutant endosperm tissues have increased precursor microRNA (pre-miRNA) and decreased mature miRNA relative to normal sibling endosperm, indicating that rgh6 is required for miRNA processing. The transcript levels for most miRNA target genes accumulate to a higher level in rgh6 mutant tissue. These results suggest that miRNA processing and regulation of miRNA target genes are required for normal endosperm development.

Plant Sciences↗
NASA NTRS1998

Collagenase and tissue plasminogen activator production in developing rat calvariae: normal progression despite fetal exposure to microgravity

Exposure to zero gravity has been shown to cause a decrease in bone formation. This implicates osteoblasts as the gravity-sensing cell in bone. Osteoblasts also are known to produce neutral proteinases, including collagenase and tissue plasminogen activator (tPA), which are thought to be important in bone development and remodeling. The present study investigated the effects of zero gravity on development of calvariae and their expression of collagenase and tPA. After in utero exposure to zero gravity for 9 days on the NASA STS-70 space shuttle mission, the calvariae of rat pups were examined by immunohistochemistry for the presence and location of these two proteinases. The ages of the pups were from gestational day 20 (G20) to postnatal (PN) day 35. Both collagenase and tPA were found to be present at all ages examined, with the greatest amount of both proteinases present in the PN14 rats. At later ages, high amounts were maintained for tPA but collagenase decreased substantially between ages PN21 to PN35. The location of collagenase was found to be associated with bone-lining cells, osteoblasts, osteocytes, and in the matrix along cement lines. In contrast, tPA was associated with endothelial cells lining the blood vessels entering bone. The presence and developmental expression of these two proteinases appeared to be unaffected by the exposure to zero gravity. The calvarial thickness of the pups was also examined; again the exposure to zero gravity showed little to no effect on the growth of the calvariae. Notably, from G20 to PN14, calvarial thickness increased dramatically, reaching a plateau after this age. It was apparent that elevated collagenase expression correlated with rapid bone growth in the period from G20 to PN14. To conclude, collagenase and tPA are present during the development of rat calvariae. Despite being produced by the same cell in vitro, i.e., the osteoblast, they are located in distinctly different places in bone in vivo. Their presence, developmental expression, and quantity do not seem to be affected by a brief exposure to zero gravity in utero.

short duration↗
NASA NTRS1964

Discussion of the General Electric proposal to develop a computer program to select thermal coatings for passive temperature control of satellites

The General Electric Company, Missiles and Space Division, submitted/a proposal to NASA for the development of an IBM 7094 computer program which would select the exterior surface coatings for passively controlling spacecraft temperatures. G. E. claims that the "trial and error" procedures currently used can be accomplished more rationally and can therefore be programmed for a digital computer. In the ASME paper, 63-HT-41, which was presented at the ASME-AIChE Heat Transfer Conference at Boston in August, 1963, Costello, Harper, and Cline, described the procedures that have been used at G. E. to develop a coating selection program subject to the following restrictions: 1. Steady-state conditions prevail, 2. Heat transfer occurs by radiation only, 3. Temperatures are optimized at only one interior point in the spacecraft, an d 4. Only the solar absorptance of the external coatings is varied to optimize temperature. The emittance must remain constant at initially specified values. General Electric proposes to develop a generalized program in three steps: 1. The program would vary both solar absorptance and hemispherical emittance to obtain the optimum coating patterns; 2. Temperatures would be optimized at more than one interior point; and 3. The equations would be modified to account for both conduction and radiation heat transfer. In the development of the general program, the scope would be restricted to steady-state heat transfer. Since the thermal designs of most spacecraft are based primarily on nearly equilibrium conditions, the proposed program could have wide application. An obvious extension of the proposed program would be to account for transient temperatures.

IBM 7090 COMPUTER↗
NASA NTRS1960

V. The X-15 flight research program in relation to the development of advanced military aircraft

The design, construction, and development of advanced military aircraft undoubtedly will involve the utilization of many relatively new concepts in several deafferent, but related, areas. In many cases, these new concepts will require new flight techniques or involve development problems inherent in the use of relatively unproven methods, materials, structures, systems, and configurations. Moreover, flight verification will be required of aircraft aerodynamics and flight behavior because of the usual uncertainties associated with predicted data. Solutions to these problems obviously would require flight testing involving extensive time and effort before the aircraft could become operationally acceptable. Upon the inception of the X-15 research airplane project, many new and far-reaching techniques and principles were studied and applied in the aircraft design and are currently being demonstrated and investigated. Because similar concepts are likely to be used in advanced military aircraft, the X-15 flight program will provide significant information, over a broad flight environment, pertinent to the development of these vehicles. This paper discusses the research objectives of the X-15 flight program, some of the flight aerodynamic characteristics currently being obtained, some development problems encountered, and the experience obtained with the advanced systems investigated.

Military aircraft↗
NASA NTRS1971

Development of a space activity suit

The development of a series of prototype space activity suit (SAS) assemblies is discussed. The SAS is a new type of pressure suit designed especially for extravehicular activity. It consists of a set of carefully tailored elastic fabric garments which have been engineered to supply sufficient counterpressure to the body to permit subjects to breath O2 at pressures up to 200 mm Hg without circulatory difficulty. A closed, positive pressure breathing system (PPBS) and a full bubble helmet were also developed to complete the system. The ultimate goal of the SAS is to improve the range of activity and decrease the energy cost of work associated with wearing conventional gas filled pressure suits. Results are presented from both laboratory (1 atmosphere) and altitude chamber tests with subjects wearing various SAS assemblies. In laboratory tests lasting up to three hours, the SAS was worn while subjects breathed O2 at pressures up to 170 mm Hg without developing physiological problems. The only physiological symptoms apparent were a moderate tachycardia related to breathing pressures above 130 mm Hg, and a small collection of edema fluid in the hands. Both problems were considered to be related to areas of under-pressurization by the garments. These problems, it is suggested, can ultimately be corrected by the development of new elastic fabrics and tailoring techniques. Energy cost of activity, and mobility and dexterity of subjects in the SAS, were found to be superior to those in comparable tests on subjects in full pressure suits.

Annis, J. F.↗
NASA NTRS1972

Developable Images Produced by X-rays Using the Nickel Hypophosphite System. 1 X-ray Sensitive Salts

Twenty-eight crystalline salts were X-irradiated and treated with an ammoniacal nickel hypophosphite solution. Treatment (development) of six of the salts resulted in precipitation of nickel metal. The developable salts were four hypophosphites, sodium phosphite, and nickel formate. A mechanism is proposed for the process based on the postulate that micro amounts of hydrogen atoms are formed during the radiation step. During development, these hydrogen atoms cause the formation of nucleation sites of nickel metal. In turn, these sites catalyze further reduction of the nickel cations by the hypophosphite. The results are discussed in terms of application of the process to the formation of developable latent images.

May, C. E.↗
NASA NTRS1972

A shuttle and space station manipulator system for assembly, docking, maintenance, cargo handling and spacecraft retrieval (preliminary design). Volume 3: Concept analysis. Part 2: Development program

A preliminary estimate is presented of the resources required to develop the basic general purpose walking boom manipulator system. It is assumed that the necessary full scale zero g test facilities will be available on a no cost basis. A four year development effort is also assumed and it is phased with an estimated shuttle development program since the shuttle will be developed prior to the space station. Based on delivery of one qualification unit and one flight unit and without including any ground support equipment or flight test support it is estimated (within approximately + or - 25%) that a total of 3551 man months of effort and $17,387,000 are required.

Source record↗
NASA NTRS1971

Patterns in the development of operations research and management science in government

The development of an operations research or management science (OR/MS) activity in an organization is discussed as occurring in a series of phases. Organizational aspects of the development of OR/MS in an individual case and in an institutional environment of federal civilian agencies are described. It is noted that there is some evidence that the length of time it takes an OR/MS group to develop to maturity has decreased. It is concluded that to understand the development of OR/MS in government organization, it must be considered as a problem in empirical organization theory.

White, M. J.↗
NASA NTRS1972

Apollo experience report: Development of guidance targeting techniques for the command module and launch vehicle

The development of the guidance targeting techniques for the Apollo command module and launch vehicle is discussed for four types of maneuvers: (1) translunar injection, (2) translunar midcourse, (3) lunar orbit insertion, and (4) return to earth. The development of real-time targeting programs for these maneuvers and the targeting procedures represented are discussed. The material is intended to convey historically the development of the targeting techniques required to meet the defined target objectives and to illustrate the solutions to problems encountered during that development.

Yencharis, J. D.↗
NASA NTRS1972

Development of an external ceramic insulation for the space shuttle orbiter

The development and evaluation of a family of reusable external insulation systems for use on the space shuttle orbiter is discussed. The material development and evaluation activities are described. Additional information is provided on the development of an analytical micromechanical model of the reusable insulation and the development of techniques for reducing the heat transfer. Design data on reusable insulation systems and test techniques used for design data generation are included.

Tanzilli, R. A.↗
NASA NTRS1971

Workshop on dimensional analysis for design, development, and research executives

The proceedings of a conference of research and development executives are presented. The purpose of the meeting was to develop an understanding of the conditions which are appropriate for the use of certain general management tools and those conditions which render these tools inappropriate. The verbatim statements of the participants are included to show the direction taken initially by the conference. Formal presentations of management techniques for research and development are developed.

Goodman, R. A.↗
NASA NTRS1972

Advanced technical developments in support of scientific experiments in space

A technique was developed for preparing solid state, lithium-drifted silicon detectors. Hollow cylindrical detectors were built and tested for possible use as anticoincidence shields to replace conventional plastic scintillators and photomultipliers. A fission cell was developed for the Pioneer F/G instruments and the IMP I subsystem. An electron current detector was developed for Jovian belt measurements of electron flux. A number of circuits and semiconductor devices was also developed.

Lamport, J. E.↗
NASA NTRS1972

Shuttle free-flying teleoperator system experiment definition. Volume 3: program development requirements

The planning data are presented for subsequent phases of free-flying teleoperator program (FFTO) and includes costs, schedules and supporting research and technology activities required to implement the free-flying teleoperator system and associated flight equipment. The purpose of the data presented is to provide NASA with the information needed to continue development of the FFTO and integrate it into the space shuttle program. The planning data describes three major program phases consisting of activities and events scheduled to effect integrated design, development, fabrication and operation of an FFTO system. Phase A, Concept Generation, represents a study effort directed toward generating and evaluating a number of feasible FFTO experiment system concepts. Phase B, Definition, will include preliminary design and supporting analysis of the FFTO, the shuttle based equipment and ground support equipment. Phase C/D, Design, Development and Operations will include detail design of the operational FFTO, its integration into the space shuttle, hardware fabrication and testing, delivery of flight hardware and support of flight operations. Emphasis is placed on the planning for Phases A and B since these studies will be implemented early in the development cycle. Phase C/D planning is more general and subject to refinement during the definition phase.

Source record↗