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At least 1,027 records · Page 57

Glycosyl-phosphatidylinositol (GPI)-anchored membrane association of the porcine reproductive and respiratory syndrome virus GP4 glycoprotein and its co-localization with CD163 in lipid rafts

The porcine reproductive and respiratory syndrome virus (PRRSV) glycoprotein 4 (GP4) resembles a typical type I membrane protein in its structure but lacks a hydrophilic tail at the C-terminus, suggesting that GP4 may be a lipid-anchored membrane protein. Using the human decay-accelerating factor (DAF; CD55), a known glycosyl-phosphatidylinositol (GPI) lipid-anchored protein, chimeric constructs were made to substitute the GPI-anchor domain of DAF with the putative lipid-anchor domain of GP4, and their membrane association and lipase cleavage were determined in cells. The DAF-GP4 fusion protein was transported to the plasma membrane and was cleaved by phosphatidylinositol-specific phospholipase C (PI-PLC), indicating that the C-terminal domain of GP4 functions as a GPI anchor. Mutational studies for residues adjacent to the GPI modification site and characterization of respective mutant viruses generated from infectious cDNA clones show that the ability of GP4 for membrane association corresponded to virus viability and growth characteristics. The residues T158 ({omega} - 2, where {omega} is the GPI moiety at E160), P159 ({omega} - 1), and M162 ({omega} + 2) of GP4 were determined to be important for virus replication, with M162 being of particular importance for virus infectivity. The complete removal of the peptide-anchor domain in GP4 resulted in a complete loss of virus infectivity. The depletion of cholesterol from the plasma membrane of cells reduced the virus production, suggesting a role of lipid rafts in PRRSV infection. Remarkably, GP4 was found to co-localize with CD163 in the lipid rafts on the plasma membrane. Since CD163 has been reported as a cellular receptor for PRRSV and GP4 has been shown to interact with this receptor, our data implicates an important role of lipid rafts during entry of the virus.

60 APPLIED LIFE SCIENCES↗

Two-Dimensional Transport Studies for the Composition and Structure of the Io Plasma Torus

Research efforts in the second quarterly period have been focused primarily upon reviewing and assessing the neutral-plasma reactions and the plasma-plasma reactions that are important in determining the production and loss rates for the primary heavy ion species S(+), S(++), S(+++), O(+), and O(++) in the plasma torus and in acquiring new and updating old cross sections for the important processes.

Smyth, William H.↗

Low-pressure hydrogen discharge maintenance in a large-size plasma source with localized high radio-frequency power deposition

The development of the two-dimensional fluid-plasma model of a low-pressure hydrogen discharge, presented in the study, is regarding description of the plasma maintenance in a discharge vessel with the configuration of the SPIDER source. The SPIDER source, planned for the neutral-beam-injection plasma-heating system of ITER, is with localized high RF power deposition to its eight drivers (cylindrical-coil inductive discharges) and a large-area second chamber, common for all the drivers. The continuity equations for the charged particles (electrons and the three types of positive ions) and for the neutral species (atoms and molecules), their momentum equations, the energy balance equations for electrons, atoms and molecules and the Poisson equations are involved in the discharge description. In addition to the local processes in the plasma volume, the surface processes of particle reflection and conversion on the walls as well as for a heat exchange with the walls are included in the model. The analysis of the results stresses on the role of the fluxes (particle and energy fluxes) in the formation of the discharge structure. The conclusion is that the discharge behavior is completely obeyed to non-locality. The latter is displayed by: (i) maximum values of plasma parameters (charged particle densities and temperatures of the neutral species) outside the region of the RF power deposition, (ii) shifted maxima of the electron density and temperature, of the plasma potential and of the electron production, (iii) an electron flux, with a vortex structure, strongly exceeding the total ion flux which gives evidence of a discharge regime of non-ambipolarity and (iv) a spatial distribution of the densities of the neutral species resulting from their fluxes.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Effects of magnetization on fusion product trapping and secondary neutron spectra

By magnetizing the fusion fuel in inertial confinement fusion (ICF) systems, the required stagnation pressure and density can be relaxed dramatically. This happens because the magnetic field insulates the hot fuel from the cold pusher and traps the charged fusion burn products. This trapping allows the burn products to deposit their energy in the fuel, facilitating plasma self-heating. Here, we report on a comprehensive theory of this trapping in a cylindrical DD plasma magnetized with a purely axial magnetic field. Using this theory, we are able to show that the secondary fusion reactions can be used to infer the magnetic field-radius product, BR, during fusion burn. This parameter, not ρR, is the primary confinement parameter in magnetized ICF. Using this method, we analyze data from recent Magnetized Liner Inertial Fusion experiments conducted on the Z machine at Sandia National Laboratories. We show that in these experiments BR ≈ 0.34(+0.14/−0.06) MG · cm, a ∼ 14× increase in BR from the initial value, and confirming that the DD-fusion tritons are magnetized at stagnation. This is the first experimental verification of charged burn product magnetization facilitated by compression of an initial seed magnetic flux.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Analysis of plasma measurements for the Geotail mission

Data processing and research efforts for the period October 1993 to September 1994 are reported. Routine data processing includes the production of color spectrograms and computing of quantitative plasma parameters such as the plasma number density, bulk flow velocity, temperature, and pressure. In addition, specialized analysis software is being developed for specific and general applications. Research activities include the measurement of plasmas from the Geotail spacecraft; the processing of the measurements from a hot plasma analyzer to compute one minute averages of plasma densities, temperatures, and velocities for a substantial part of the Geotail deep tail mission; and, a preliminary survey of the magnetotail for geocentric radial distances of 10 to 210 earth radii. The topology of the magnetotail with its various regions and boundaries is determined by a complex interaction with the fields and plasmas of the solar wind. Observations of the rotation of the magnetic field in the solar wind show that it is well correlated with repeated transitions at Geotail from the magnetotail lobe to a magnetosheath-like boundary layer.

Frank, Louis A.↗

Advances and directions of ion nitriding/carburizing

Ion nitriding and carburizing are plasma activated thermodynamic processes for the production of case hardened surface layers not only for ferrous materials, but also for an increasing number of nonferrous metals. When the treatment variables are properly controlled, the use of nitrogenous or carbonaceous glow discharge medium offers great flexibility in tailoring surface/near-surface properties independently of the bulk properties. The ion nitriding process has reached a high level of maturity and has gained wide industrial acceptance, while the more recently introduced ion carburizing process is rapidly gaining industrial acceptance. The current status of plasma mass transfer mechanisms into the surface regarding the formation of compound and diffusion layers in ion nitriding and carbon build-up ion carburizing is reviewed. In addition, the recent developments in design and construction of advanced equipment for obtaining optimized and controlled case/core properties is summarized. Also, new developments and trends such as duplex plasma treatments and alternatives to dc diode nitriding are highlighted.

Spalvins, Talivaldis↗

Shedding light on thermal photon and dilepton production

Electromagnetic radiation from the quark-gluon plasma (QGP) is an important observable to be considered in heavy ion collision experiments. I will provide an update on recent advancements from perturbation theory and quenched lattice simulations. The resummed next-to-leading order (NLO) emission rate has recently been decomposed into transverse and longitudinal components, and extended to non-zero baryon chemical potential. The associated spectral function has also been tested against the Euclidean correlator, for continuum-extrapolated lattice data (at μ B = 0).

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

Production of negative ions on graphite surface in H{sub 2}/D{sub 2} plasmas: Experiments and srim calculations

In previous works, surface-produced negative-ion distribution-functions have been measured in H{sub 2} and D{sub 2} plasmas using graphite surfaces (highly oriented pyrolitic graphite). In the present paper, we use the srim software to interpret the measured negative-ion distribution-functions. For this purpose, the distribution-functions of backscattered and sputtered atoms arising due to the impact of hydrogen ions on a-CH and a-CD surfaces are calculated. The srim calculations confirm the experimental deduction that backscattering and sputtering are the mechanisms of the origin of the creation of negative ions at the surface. It is shown that the srim calculations compare well with the experiments regarding the maximum energy of the negative ions and reproduce the experimentally observed isotopic effect. A discrepancy between calculations and measurements is found concerning the yields for backscattering and sputtering. An explanation is proposed based on a study of the emitted-particle angular-distributions as calculated by srim.

75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND↗

Magnetic field effects on ionization inhomogeneities advected by motions of the neutral gas

A theory is developed for the ambipolar diffusion, drift, distortion, and production of ionization inhomogeneities within weakly ionized plasma in the presence of the geomagnetic field and motions of the neutral gas. The theory developed includes spatially varying velocity fields of the neutral gas, with a special emphasis on investigating the length scale restrictions necessary for the plasma to be treated as spatially homogeneous. Several effects of the magnetic field on ionization inhomogeneities are discussed. These include the anisotropy of ambipolar diffusion, the distortion and drift due to a gravitational field, the production of irregularities due to the turbulent acceleration field, the drift relative to the neutral gas, and the distortion of ionization inhomogeneities due to the effects of a uniform wind. Pertinent equations are derived for a multispecies plasma containing positive or negative ions, and for the case of electrons and one species of positive ions.

Hill, R. J.↗

Vitrification as an alternative to landfilling of tannery sewage sludge

Highlights: • The possibility of vitrification of tannery sewage sludge was investigated. • Glass cullet was substituted with different wastes of mineral character. • Component ratio in the processed mixtures was optimized. • Environmental safety of the acquired vitrificates was verified. • An alternative management approach of usually landfilled waste was presented. - Abstract: Due to high content of heavy metals such as chromium, tannery sewage sludge is a material which is difficult to be biologically treated as it is in the case of organic waste. Consequently, a common practice in managing tannery sewage sludge is landfilling. This poses a potential threat to both soil and water environments and it additionally generates costs of construction of landfills that meet specific environment protection requirements. Vitrification of this kind of sewage sludge with the addition of mineral wastes can represent an alternative to landfilling. The aim of this study was to investigate the possibility of obtaining an environmentally safe product by means of vitrification of tannery sewage sludge from a flotation wastewater treatment process and chemical precipitation in order to address the upcoming issue of dealing with sewage sludge from the tannery industry which will be prohibited to be landfilled in Poland after 2016. The focus was set on determining mixtures of tannery sewage sludge with additives which would result in the lowest possible heavy metal leaching levels and highest hardness rating of the products obtained from their vitrification. The plasma vitrification process was carried out for mixtures with various amounts of additives depending on the type of sewage sludge used. Only the materials of waste character were used as additives. One finding of the study was an optimum content of mineral additives in vitrified mixture of 30% v/v waste molding sands with 20% v/v carbonate flotation waste from the zinc and lead industry for the formulations with flotation sewage sludge, and 45% v/v and 5% v/v, respectively, for precipitation sewage sludge. These combinations allowed for obtaining products with negligible heavy metal leaching levels and hardness similar to commercial glass, which suggests they could be potentially used as construction aggregate substitutes. Incineration of sewage sludge before the vitrification process lead to increased hardness of the vitrificates and reduced leaching of some heavy metals.

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗

Generating X-ray in MeV regime from interactions of mono-energetic electrons with Sn and Pb

Quasi mono-energetic x-ray beams generated from thin targets by interaction of mono-energetic electron beams from 600 mJ, 80 fs laser pulse. A micron-scale laser-produced plasma creates, accelerates relativistic mono-energetic electron bunches. As such electrons propagate in the ion channel produced in the wake of the laser pulse; the accelerated electrons can interact with Sn, Pb targets and generate X-ray radiation of MeV energy and MeV/cm2 flux.

43 PARTICLE ACCELERATORS↗

The effect of cathode geometry on barium transport in hollow cathode plasmas

The effect of barium transport on the operation of dispenser hollow cathodes was investigated in numerical modeling of a cathode with two different orifice sizes. Despite large differences in cathode emitter temperature, emitted electron current density, internal xenon neutral and plasma densities, and size of the plasma-surface interaction region, the barium transport in the two geometries is qualitatively very similar. Barium is produced in the insert and flows to the surface through the porous structure. A buildup of neutral Ba pressure in the plasma over the emitter surface can suppress the reactions supplying the Ba, restricting the net production rate. Neutral Ba flows into the dense Xe plasma and has a high probability of being ionized at the periphery of this zone. The steady state neutral Ba density distribution is determined by a balance between pressure gradient forces and the drag force associated with collisions between neutral Ba and neutral Xe atoms. A small fraction of the neutral Ba is lost upstream. The majority of the neutral Ba is ionized in the high temperature Xe plasma and is pushed back to the emitter surface by the electric field. The steady state Ba{sup +} ion density distribution results from a balance between electrostatic and pressure forces, neutral Xe drag and Xe{sup +} ion drag with the dominant forces dependent on location in the discharge. These results indicate that hollow cathodes are very effective at recycling Ba within the discharge and therefore maintain a high coverage of Ba on the emitter surface, which reduces the work function and sustains high electron emission current densities at moderate temperatures. Barium recycling is more effective in the cathode with the smaller orifice because the Ba is ionized in the dense Xe plasma concentrated just upstream of the orifice and pushed back into the hollow cathode. Despite a lower emitter temperature, the large orifice cathode has a higher Ba loss rate through the orifice because the Xe plasma density peaks further upstream.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Lasing of extreme ultraviolet light with nitrogen plasma in a recombining phase-Roles of doubly excited states

Focused are the properties of population inversion with nitrogen plasma between n = 3 and 2 of a hydrogen-like state in a recombining phase. The population inversion is calculated in the framework of population kinetics, and the gain coefficient G is estimated. The maximum plasma length L is approximated by a product of the duration of population inversion {tau}{sub e} and the speed of light c. In the calculation, dielectronic-capture ladderlike (DL) processes are considered. At the plasma ion densities of 10{sup 17-18} cm{sup -3} with a rapid cooling, the DL deexcitations make a large contribution to the population inversion, resulting in GL=5-10, and the prescription of plasma cooling is found to be definitely critical.

74 ATOMIC AND MOLECULAR PHYSICS↗

Space Technology for the Iron Foundry

Electric Power Research Institute (EPRI) initiated development of a plasma melter intended to solve a major problem in the U.S. foundry industry. EPRI is a non-profit organization that manages research and development for some 600 electric utility member companies. For the plasma melter program, EPRI enlisted as co-sponsors Westinghouse Electric's Environmental Systems and Services Division, General Motors Corporation, and Modern Equipment Company, supplier of equipment and services to the foundry industry. General Motor's plasma melter, first in the U.S., is an advanced technology system designed to improve the efficiency of coke-burning cupolas that melt iron to produce automotive castings. The key elements are six Westinghouse plasma torches. Electrically-powered plasma torch creates an ionized gas that superheats air entering the cupola to 10,000 degrees Fahrenheit. That great heat, three times higher than that attainable by oil or natural gas systems, is the key to making iron cheaper, cleaner, and faster. System offers an environmental bonus in reduced cupola emissions. Plasma torches increase GM's electric bill at Defiance, but that cost is more than compensated by the savings in charge material. The EPRI-sponsored Center for Materials Production (CMP) is evaluating the potential of plasma cupola technology.

Source record↗

Nanoparticle dynamics in the spatial afterglows of nonthermal plasma synthesis reactors

Nonthermal plasma flow tube reactors are industrially scalable systems for the production of nanocrystal (NC) based materials and coatings. One key advantage of nonthermal plasma synthesis is the ability to both synthesize NCs and deposit films in a single reactor, as at the reactor outlet, NCs can be inertially deposited onto a target substrate. The size and morphology of deposited particles can substantially influence the film structure and function. Though NCs are typically near-spherical and monodispersed as-produced in plasma synthesis reactors, NC charge and growth dynamics can be altered substantially when NCs are sampled out of the plasma and through the spatial afterglow region, affecting deposition. Experiments have demonstrated changes of NC size and charge in the spatial afterglow; however, these dynamics remain unexplored and unexplained via theory and simulation. To address this, we developed a constant number Monte Carlo (CNMC) simulation model to examine the mechanisms of NC decharging and growth in the spatial afterglow of plasma flow tube reactors. Collisions between NC and plasma species, diffusive deposition, and electron desorption from NCs are incorporated in the CNMC simulation. The simulation results are specifically compared with previous experiments on Si NCs synthesized from a low pressure Ar-SiH 4 nonthermal plasma reactor. Furthermore, the experiment-model comparison shows that CNMC models can be implemented which accurately model NC size distribution evolution in a spatial afterglow. Simultaneously, results show that improved collision models, energetic species diffusion models, and electron desorption models will be necessary to accurately depict NC dynamics in spatial afterglows.

42 ENGINEERING↗

VARIABLE GAMMA-RAY EMISSION FROM THE CRAB NEBULA: SHORT FLARES AND LONG 'WAVES'

Gamma-ray emission from the Crab Nebula has been recently shown to be unsteady. In this paper, we study the flux and spectral variability of the Crab above 100 MeV on different timescales ranging from days to weeks. In addition to the four main intense and day-long flares detected by AGILE and Fermi-LAT between 2007 September and 2012 September, we find evidence for week-long and less intense episodes of enhanced gamma-ray emission that we call 'waves'. Statistically significant 'waves' show timescales of 1-2 weeks, and can occur by themselves or in association with shorter flares. We present a refined flux and spectral analysis of the 2007 September-October gamma-ray enhancement episode detected by AGILE that shows both 'wave' and flaring behavior. We extend our analysis to the publicly available Fermi-LAT data set and show that several additional 'wave' episodes can be identified. We discuss the spectral properties of the 2007 September 'wave'/flare event and show that the physical properties of the 'waves' are intermediate between steady and flaring states. Plasma instabilities inducing 'waves' appear to involve spatial distances l {approx} 10{sup 16} cm and enhanced magnetic fields B {approx} (0.5-1) mG. Day-long flares are characterized by smaller distances and larger local magnetic fields. Typically, the deduced total energy associated with the 'wave' phenomenon (E{sub w} {approx} 10{sup 42} erg, where E{sub w} is the kinetic energy of the emitting particles) is comparable with that associated to the flares, and can reach a few percent of the total available pulsar spin-down energy. Most likely, flares and waves are the product of the same class of plasma instabilities that we show acting on different timescales and radiation intensities.

79 ASTRONOMY AND ASTROPHYSICS↗

Avoiding fusion plasma tearing instability with deep reinforcement learning

For stable and efficient fusion energy production using a tokamak reactor, it is essential to maintain a high-pressure hydrogenic plasma without plasma disruption. Therefore, it is necessary to actively control the tokamak based on the observed plasma state, to manoeuvre high-pressure plasma while avoiding tearing instability, the leading cause of disruptions. This presents an obstacle-avoidance problem for which artificial intelligence based on reinforcement learning has recently shown remarkable performance. However, the obstacle here, the tearing instability, is difficult to forecast and is highly prone to terminating plasma operations, especially in the ITER baseline scenario. Previously, we developed a multimodal dynamic model that estimates the likelihood of future tearing instability based on signals from multiple diagnostics and actuators. Here we harness this dynamic model as a training environment for reinforcement-learning artificial intelligence, facilitating automated instability prevention. We demonstrate artificial intelligence control to lower the possibility of disruptive tearing instabilities in DIII-D, the largest magnetic fusion facility in the United States. The controller maintained the tearing likelihood under a given threshold, even under relatively unfavourable conditions of low safety factor and low torque. In particular, it allowed the plasma to actively track the stable path within the time-varying operational space while maintaining H-mode performance, which was challenging with traditional preprogrammed control. This controller paves the path to developing stable high-performance operational scenarios for future use in ITER.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Negative hydrogen ion beam extracted from a Bernas-type ion source

Negative hydrogen (H{sup -}) ion beam was produced without cesium seeding by a Bernas-type ion source with a coaxial hot cathode. The amount of H{sup -} ion beam current extracted from an original Bernas-type ion source using a hairpin shape filament as a hot cathode was 1 {mu}A with the 0.4 A arc current, while that 300 eV beam energy. In the other hand, H{sup -} ion beam current using the Bernas-type ion source with a coaxial hot cathode reached 4 {mu}A under the same condition. Production efficiency was enhanced by the focused plasma produced by a coaxial hot cathode.

43 PARTICLE ACCELERATORS↗