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At least 1,045 records · Page 58

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DOE OSTI2024

Mechanical morphotype switching as an adaptive response in mycobacteria

Invading microbes face a myriad of cidal mechanisms of phagocytes that inflict physical damage to microbial structures. How intracellular bacterial pathogens adapt to these stresses is not fully understood. Here, we report the discovery of a virulence mechanism by which changes to the mechanical stiffness of the mycobacterial cell surface confer refraction to killing during infection. Long-term time-lapse atomic force microscopy was used to reveal a process of “mechanical morphotype switching” in mycobacteria exposed to host intracellular stress. A “soft” mechanical morphotype switch enhances tolerance to intracellular macrophage stress, including cathelicidin. Both pharmacologic treatment, with bedaquiline, and a genetic mutant lacking uvrA modified the basal mechanical state of mycobacteria into a soft mechanical morphotype, enhancing survival in macrophages. Our study proposes microbial cell mechanical adaptation as a critical axis for surviving host-mediated stressors.

59 BASIC BIOLOGICAL SCIENCES↗

DOE OSTI2024

Field-free deterministic switching of all–van der Waals spin-orbit torque system above room temperature

Two-dimensional van der Waals (vdW) magnetic materials hold promise for the development of high-density, energy-efficient spintronic devices for memory and computation. Recent breakthroughs in material discoveries and spin-orbit torque control of vdW ferromagnets have opened a path for integration of vdW magnets in commercial spintronic devices. However, a solution for field-free electric control of perpendicular magnetic anisotropy (PMA) vdW magnets at room temperatures, essential for building compact and thermally stable spintronic devices, is still missing. Here, we report a solution for the field-free, deterministic, and nonvolatile switching of a PMA vdW ferromagnet, Fe 3 GaTe 2 , above room temperature (up to 320 K). We use the unconventional out-of-plane anti-damping torque from an adjacent WTe 2 layer to enable such switching with a low current density of 2.23 × 10 6 A cm –2 . This study exemplifies the efficacy of low-symmetry vdW materials for spin-orbit torque control of vdW ferromagnets and provides an all-vdW solution for the next generation of scalable and energy-efficient spintronic devices.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

DOE OSTI2017

State switching kinetics for quasi-one-dimensional nanosystems: Effects of Finite length and irradiation

The state switching in an extended quasi-one-dimensional material is modeled by the stochastic formation of local new-state nuclei and their subsequent growth along the system axis. An analytical approach is developed to describe the influence of defects, dividing a sample into an ensemble of finite-length segments, on its state switching kinetics. As applied to magnetic systems, the method makes it possible to calculate magnetization curves for different defect concentrations and parameters of material.

75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND↗

DOE OSTI2015

Conditions of steady switching in phase-transition memory cells

Three types of non-volatile memory cells of different designs based on phase transitions are developed and implemented. The effect of the design features of the cells and their active-region sizes on the switching characteristics and normal operation of the cells is considered as a whole. The causes of failure of the cells are analyzed from the obtained series of scanning electron images upon level-by-level etching of the samples. It is shown that the cell design is the most critical factor from the viewpoint of switching to the high-resistance state. The causes of this fact are analyzed and the criterion for providing the steady operation of cells of non-volatile memory based on phase transitions is formulated.

75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND↗

DOE OSTI2015

On the size-dependent magnetism and all-optical magnetization switching of transition-metal silicide nanostructures

Theoretical investigations of the electronic structure, synthesis, and all-optical magnetization switching of transition-metal silicide nanostructures are reported. The magnetic moment of the nanostructures is studied as a function of the silicide cluster size and configuration. The experimentally demonstrated magnetization switching of nanostructured nickel silicide by circularly polarized light makes it possible to create high-speed storage devices with high density data recording.

36 MATERIALS SCIENCE↗

DOE OSTI2019

The Influence of Switching between Chaotic Regimes on the Correlation Characteristics of Nonlinear Systems

The problem of dynamic regime diagnostics in nonlinear systems using their experimental time series is studied in the presence of switching between various oscillatory processes. Interpretation of such data can be affected by errors in the calculated correlation characteristics caused by the presence of fragments corresponding to different dynamic regimes. It is shown that the switching between various regimes more significantly influences the diagnostics of anticorrelated dynamics.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

DOE OSTI2021

High energy (0.8 J) mechanically Q-switched 2.94 μm Er:YAG laser

We report a flashlamp pumped mechanically Q-switched (MQS) 2.94 μm Er:YAG laser based on a spinning mirror with a highest output energy of 805 mJ at a pulse duration of 61 ns and 13 MW of peak power at 1 Hz repetition rate. This record output energy was achieved with the use of 300 mm long MQS Er:YAG laser cavity consisting of a 70% output coupler, 7 × 120 mm AR coated Er(50%):YAG crystal, and 4200 rad/s angular speed of the spinning mirror. The pulse jitter was also measured by using optical triggering and was smaller than 10 ns for 150 ns Q-switched pulses, which could be applicable to many laser applications where precise synchronization of pulses is required.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

DOE OSTI2020

Hot-pressed ceramic Fe:ZnSe gain-switched laser

We report the first room temperature gain-switched Fe:ZnSe hot-pressed ceramic laser pumped by 2.94 µm radiation of mechanically Q-switched Er:YAG laser. The maximum output energy at 4.2 µm was 41 mJ at 3 Hz repetition rate and 120 ns pulse duration. The measured slope efficiency was 25% with respect to the absorbed energy. This technique could be attractive for the future development of high-energy short-pulse solid-state mid-IR systems.

36 MATERIALS SCIENCE↗

DOE OSTI2025

Theoretical perspective on phase stability and polarization switching in ferroelectric hafnia

Fluorite-based ferroelectric materials are revolutionizing the application space of polar semiconductors. These materials leverage robust polarization of extremely thin films, compatibility with the silicon chip processing, and decades of manufacturing experience to enable a new generation of ferroelectric memory devices. As a new paradigm for ferroelectrics, understanding of phase transitions and the switching mechanism in fluorites is essential both for advancing applications and for fundamental science. In this article, we outline the recent progress that has been made to understand the relative phase stability, phase transition and order parameter coupling, ferroelectric switching through unique nucleation and growth processes, and how defects affect these phases and processes. The main challenges, opportunities, and next steps for leveraging these materials for next-generation devices are reviewed.

Condensed Matter Physics↗

DOE OSTI2022

Switching the conductance of a single molecule: Lessons from molecular junctions

The concept of using single molecules as functional building blocks in electronic circuitry represents the ultimate device miniaturization and has garnered tremendous attention from physics, chemistry, and engineering. Recent advances in single-molecule junction techniques have enabled direct investigation of charge transport in a quasi-one-dimensional conduction channel composed of an individual molecule. Furthermore, one of the main research focuses over the past decade has been to understand the conductance switching effect of single molecules as it is essential for developing molecular-scale optoelectronics, computing, and sensing applications. In this perspective, we highlight the established physical and chemical mechanisms for single-molecule conductance switching behavior and examine the associated stimuli in single-molecule junction systems.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

DOE OSTI2017

The Implementation Of Solid State Switches In A Parallel Configuration To Gain Output Current Capacity In A High Current Capacitive Discharge Unit (CDU).

For my project I have selected to research and design a high current pulse system, which will be externally triggered from a 5V pulse. The research will be conducted in the region of paralleling the solid state switches for a higher current output, as well as to see if there will be any other advantages in doing so. The end use of the paralleled solid state switches will be used on a Capacitive Discharge Unit (CDU). For the first part of my project, I have set my focus on the design of the circuit, selection of components, and simulation of the circuit.

42 ENGINEERING↗

DOE OSTI2017

Fast Switching Magnet for Heavy Ion Beam Separation

Fast magnets for multiplexing ion beams between different beamlines are technologically challenging and expensive, but there is an ever-growing need to develop such systems for beam separation at research and industrial facilities. For example, The Argonne Tandem Linac Accelerator System (ATLAS) is planning to expand its operations as a multi-user facility and there is a clear need, presently unmet by the industry, for a switching magnet system with the sub-millisecond transient times.In response to this problem, RadiaBeam Technologies is developing a novel pulsed switching magnet system capable of producing a 1.1T peak field over 45 cm length with a short (<1 ms) rise and fall time. The key enabling innovation in this project is an introduction of a solid-state interposed modulator architecture, which enables to improve magnet performance and reliability and reduce the cost to a practical level.

43 PARTICLE ACCELERATORS↗

DOE OSTI2023

Laser-Induced Ultrafast Demagnetization and Spin Switching (Final Report)

The information technology revolution demands bigger and faster magnetic storage devices. The funded research focuses on a new frontier - Laser-induced ultrafast all-optical spin switching (AOS), where a single laser pulse can switch spins from one direction to another permanently, without a magnetic field, on a time scale of 1-10 picoseconds, 2-3 orders of magnitude faster than the existing technology. The funded research has successfully resolved a long-standing issue in ultrafast demagnetization whether the lattice contributes to the demagnetization. We developed a high level first-principles theory and employed a massively parallel computer to pin down the details of the physical mechanisms that are inaccessible to other methods. This unique feature allows us to compute the force on each atom in both bulk and monolayer systems. We find that it is indeed true there is a nonzero force on each atom, but the idea of vibration contribution is not crucial to our basic understanding of physics. This paves the way to future experimental, theoretical and technological developments.

75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND↗

DOE OSTI2019

Laboratory Evaluation and Field Demonstration of High Rotor Switched Reluctance Motor (HRSRM) Technology

In this project, a new motor technology based on a novel design called a High Rotor Pole Switched Reluctance Motor (HRSRM) was demonstrated and evaluated. The HRSRM system combines an innovative electric motor design with a programmable variable-speed drive and a controller that provides real time monitoring and cloud-based connectivity. Unlike induction or permanent-magnet motor designs, this motor uses a switched reluctance (SR) design that purports to be simpler to manufacture and more reliable and efficient to operate. Several of the stated benefits of the HRSRM system were evaluated as part of this project. First, the technology is claimed to offer greater energy efficiency than any motor currently on the market. Second, according to the manufacturer, the motor can be dropped into an existing pump or heating, ventilation, and air-conditioning application in less than 30 minutes, and has controls that can be pre-programmed to interact with the application’s existing control structure. Third, the control system allows the HRSRM to replace a constant-speed motor with one that provides variable-speed capabilities without requiring the installation of a variable-speed drive. The evaluation of a 10 hp HRSRM system was conducted in two parts. One portion of the evaluation consisted of performance tests conducted in a tightly controlled laboratory environment in which the performance of the HRSRM system was compared with that of a premium efficiency induction motor with a variable-frequency drive. The other portion of the evaluation was conducted at a field location within a General Services Administration facility in which the HRSRM system replaced an existing motor system in a 10 hp chilled water pump. The performance of the HRSRM system was compared with that of the incumbent motor system that was supplied with the pump from the manufacturer. The overall project and performance objectives for this motor evaluation are defined in Table ES.1.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

DOE OSTI2024

Entropy Analysis of FPGA Interconnect and Switch Matrices for Physical Unclonable Functions

Random variations in microelectronic circuit structures represent the source of entropy for physical unclonable functions (PUFs). In this paper, we investigate delay variations that occur through the routing network and switch matrices of a field-programmable gate array (FPGA). The delay variations are isolated from other components of the programmable logic, e.g., look-up tables (LUTs), flip-flops (FFs), etc., using a feature of Xilinx FPGAs called dynamic partial reconfiguration (DPR). A set of partial designs is created to fix the placement of a time-to-digital converter (TDC) and supporting infrastructure to enable the path delays through the target interconnect and switch matrices to be extracted by subtracting out common-mode delay components. Delay variations are analyzed in the different levels of routing resources available within FPGAs, i.e., local routing and across-chip routing. Data are collected from a set of Xilinx Zynq 7010 devices, and a statistical analysis of within-die variations in delay through a set of the randomly-generated and hand-crafted interconnects is presented.

97 MATHEMATICS AND COMPUTING↗

DOE OSTI2025

Sub-Nanosecond, Room-Temperature, Mid-IR Fe:ZnSe Gain-Switched Laser: Experimental Characterization and Modeling

We present the modeling and experimental characterization of a room-temperature, sub-nanosecond, gain-switched (GS) Fe:ZnSe laser operating at 4.4–4.8 μm. As pump sources, we used a 2.79 µm Q-switched Cr:Er:YSGG laser with a pulse duration of 52 ns and the 2.98 μm idler of a Nd:YAG pumped KTA-OPO system with a pulse duration of 9 ns. The shortest pulse durations were measured to be 1.4 ns and 0.7 ns under excitation by the Cr:Er:YSGG laser and KTA-OPO system, respectively. The developed Fe:ZnSe laser model showed good agreement with the experimental results. Optimization of the laser parameters based on model simulations suggests that an Fe:ZnSe microchip laser configuration could be achieved with a pulse duration of ~250 ps and an efficiency of ~20%.

Ghimire, Saugat↗

DOE OSTI2016

A deep campaign to characterize the synchronous radio/X-ray mode switching of PSR B0943+10

Observations of PSR B0943+10 with XMM-Newton and the LOFAR, LWA, and Arecibo radio telescopes in 2014 November confirm the synchronous X-ray/radio switching between a radio-bright (B) mode and a radio-quiet (Q) mode, in which the X-ray flux is a factor ∼2.4 higher than in the B-mode. We discovered X-ray pulsations during the B-mode (0.5–2 keV pulsed fraction of (38 ± 5)%) and confirm their presence in the Q-mode, where the pulsed fraction increases with energy from ∼20% to ∼65% at 2 keV. We found marginal evidence for an increase in the X-ray pulsed fraction during the B-mode on a timescale of hours. The X-ray spectrum during the Q-mode requires a fit with either a power law plus blackbody or the sum of two blackbodies, while in the B-mode it is well fit by a single blackbody (a single power law is rejected). In the Q-mode, the pulsed emission has a blackbody spectrum with temperature ∼3.4×10{sup 6} K and the unpulsed emission is a power law with photon index ∼2.5, while during the B-mode both the pulsed and unpulsed emission can be fit by either a blackbody or a power law with similar values of temperature and index. A Chandra image does not show diffuse X-ray emission. These results support a scenario in which unpulsed non-thermal emission, likely magnetospheric, and pulsed thermal emission from a small polar cap (∼1500 m{sup 2}) with a non-dipolar field (∼10{sup 14} G) are present during both modes and vary in a correlated way. This is broadly consistent with the partially screened gap model and does not necessarily imply global magnetospheric rearrangements to explain the mode switching.

79 ASTRONOMY AND ASTROPHYSICS↗

DOE OSTI2016

Crystal structure of an HIV assembly and maturation switch

Virus assembly and maturation proceed through the programmed operation of molecular switches, which trigger both local and global structural rearrangements to produce infectious particles. HIV-1 contains an assembly and maturation switch that spans the C-terminal domain (CTD) of the capsid (CA) region and the first spacer peptide (SP1) of the precursor structural protein, Gag. The crystal structure of the CTD-SP1 Gag fragment is a goblet-shaped hexamer in which the cup comprises the CTD and an ensuing type II β-turn, and the stem comprises a 6-helix bundle. The β-turn is critical for immature virus assembly and the 6-helix bundle regulates proteolysis during maturation. This bipartite character explains why the SP1 spacer is a critical element of HIV-1 Gag but is not a universal property of retroviruses. Our results also indicate that HIV-1 maturation inhibitors suppress unfolding of the CA-SP1 junction and thereby delay access of the viral protease to its substrate.

59 BASIC BIOLOGICAL SCIENCES↗