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At least 109 records · Page 6

Do Integrins Mediate the Skeletal Response to Altered Loading?

In vivo experiments were performed to examine the role of B1 integrin in skeletal adaptation to reduced and increased loading. Transgenic mice were generated with a dominant negative form of the B1 integrin cytoplasmic domain with expression driven by the osteocalcin promoter (pOCb1DN). This fragment consists of the transmembrane and intracellular domains and interferes with endogenous integrin signalling in vitro. This promoter targets expression of the transgene to mature bone cells. Expression of the transgene was confirmed by immunoprecipitation and western blotting. Reduced loading was generated by hindlimb suspension and increased loading the resumption of normal loading following hindlimb suspension. Two groups of female 35-day old mice were examined: poCb1DN transgenic mice (TG) and wild-type littermate controls (WT). Animals were hindlimb suspended for 1 week (HU, n = l0/gp) or 4 weeks (HU, n = 4 - 7/gp) or suspended for 4 weeks followed by reloading by normal ambulation for 4 weeks (RL, n = l0/gp). Age-matched controls (CT) were pairfed based on the HU food intake. The protocols were approved by the NASA Ames Research Center IACUC. Upon completion of the experimental protocol, body mass was recorded and tissues of interest removed and analyzed following standard procedures. Femoral whole bone structural behavior was measured in torsion to failure to obtain whole bone strength (failure torque) and torsional rigidity. Ash content (ash) and fraction (% ash) were determined for the tibia. Total ash is indicative of bone size whereas %ash is a material property. Tibial curvature was measured from microradiographs. For each experiment, the effects of genotype (TG, WT) and treatment (CT, HU/RL) were assessed by two-factor ANOVA followed by the Tukey-Kramer posthoc to identify significant differences at an alpha level of 0.05. Our goal was to understand differences resulting from altered integrin function in the adaptation to altered loading.

vanderMeulen, Marjolein C. H.↗

Raw liquid waste treatment process

A raw sewage treatment process is disclosed in which substantially all the non-dissolved matter, which is suspended in the sewage water is first separated from the water, in which at least organic matter is dissolved. The non-dissolved material is pyrolyzed to form an activated carbon and ash material without the addition of any conditioning agents. The activated carbon and ash material is added to the water from which the non-dissolved matter was removed. The activated carbon and ash material absorbs organic matter and heavy metal ions, it is believed, are dissolved in the water and is thereafter supplied in a counter current flow direction and combined with the incoming raw sewage to facilitate the separation of the non-dissolved settleable materials from the sewage water. The used carbon and ash material together with the non-dissolved matter which was separated from the sewage water are pyrolyzed to form the activated carbon and ash material.

Humphrey, Marshall F.↗

MISR Observations of Etna Volcanic Plumes

In the last twelve years, Mt. Etna, located in eastern Sicily, has produced a great number of explosive eruptions. Volcanic plumes have risen to several km above sea level and created problems for aviation and the communities living near the volcano. A reduction of hazards may be accomplished using remote sensing techniques to evaluate important features of volcanic plumes. Since 2000, the Multiangle Imaging SpectroRadiometer (MISR) on board NASA s Terra spacecraft has been extensively used to study aerosol dispersal and to extract the three-dimensional structure of plumes coming from anthropogenic or natural sources, including volcanoes. In the present work, MISR data from several explosive events occurring at Etna are analyzed using a program named MINX (MISR INteractive eXplorer). MINX uses stereo matching techniques to evaluate the height of the volcanic aerosol with a precision of a few hundred meters, and extracts aerosol properties from the MISR Standard products. We analyzed twenty volcanic plumes produced during the 2000, 2001, 2002-03, 2006 and 2008 Etna eruptions, finding that volcanic aerosol dispersal and column height obtained by this analysis is in good agreement with ground-based observations. MISR aerosol type retrievals: (1) clearly distinguish volcanic plumes that are sulphate and/or water vapor dominated from ash-dominated ones; (2) detect even low concentrations of volcanic ash in the atmosphere; (3) demonstrate that sulphate and/or water vapor dominated plumes consist of smaller-sized particles compared to ash plumes. This work highlights the potential of MISR to detect important volcanic plume characteristics that can be used to constrain the eruption source parameters in volcanic ash dispersion models. Further, the possibility of discriminating sulphate and/or water vapor dominated plumes from ash-dominated ones is important to better understand the atmospheric impact of these plumes.

Scollo, S.↗

Stratigraphic Evidence for Early Martian Explosive Volcanism in Arabia Terra

Several large paterae in Arabia Terra are suggested to be calderas that produced colossal explosive eruptions (i.e., supereruptions). If these features are indeed explosive calderas, dispersion modeling suggests extensive ash deposits should be common throughout the region. However, such deposits have not previously been linked with the suggested calderas. Here, we describe layered deposits containing minerals both consistent with and diagnostic of altered volcanic ash throughout Arabia Terra. These deposits include Al-dominant minerals such as montmorillonite, imogolite, and allophane among others. Altered ash deposits are found to thin (from 1-km to 100-m thickness) away from the suggested calderas. We estimate that the volcanic ash observed in Arabia Terra is the result of between 1,000 and 2,000 individual explosive eruptions over 500-million years. Our observations support the hypothesis that Arabia Terra hosted supereruptions in the late Noachian-early Hesperian that repeatedly blanketed the region with layers of ash.

Patrick Whelley↗

The Staring OBservations of the Atmosphere (SOBA) Mission Concept

The Staring OBservations of the Atmosphere (SOBA) Mission is a concept that was developed and matured under the guidance of the NASA Ames Project EXellence (APEX) program. If funded, it will provide an unprecedented opportunity to improve ash transport forecasts and climate model simulations associated with volcanic eruptions. NASA and National science objectives require a better understanding of volcanic aerosol and trace gas emissions, transport, chemical transformation, and deposition, since they impact Earth's climate and atmospheric composition, human health, and aviation safety. Natural hazards such as the 2010 eruption of the Eyjafjallajökull volcano in Iceland demonstrated how existing remote-sensing assets were inadequate for individual volcanic event monitoring. During this eruption, available instruments were unable to provide data necessary to initialize volcanic plume transport models so that they could accurately predict the quantity and location of volcanic ash. As a result, thousands of flights around the world were grounded unnecessarily, at great expense. Volcanoes can also play a large role in regulation of the Earth's climate, so SOBA observations will also be used to evaluate and improve volcanic aerosol and trace gas simulation in chemical transport models (CTMs) and global climate models (GCMs). We propose the development of an airborne remote sensing concept and field campaign that will respond to an eruption and provide near real time observations of a volcanic plume, specifically ash injection height, transport, aerosol microphysical physical properties, and the location and concentration of sulfur dioxide (SO2) (sulfate (SO42-) aerosol precursor). This airborne system will utilize a depolarization sensitive, downward looking Light Detection And Ranging (lidar) instrument and an ultraviolet (UV) imaging spectrometer, and will provide data to be ingested by volcanic ash advisory models. Furthermore, the lessons learned in the development of this system could eventually guide regular deployment of similar systems by NASA or other government agencies.

Aerosols↗

Fluidized bed coal combustion reactor

A fluidized bed coal reactor includes a combination nozzle-injector ash-removal unit formed by a grid of closely spaced open channels, each containing a worm screw conveyor, which function as continuous ash removal troughs. A pressurized air-coal mixture is introduced below the unit and is injected through the elongated nozzles formed by the spaces between the channels. The ash build-up in the troughs protects the worm screw conveyors as does the cooling action of the injected mixture. The ash layer and the pressure from the injectors support a fluidized flame combustion zone above the grid which heats water in boiler tubes disposed within and/or above the combustion zone and/or within the walls of the reactor.

Moynihan, P. I.↗

Characterization of polymer decomposition products by laser desorption mass spectrometry

Laser desorption mass spectrometry has been used to characterize the ash-like substances formed on the surfaces of polymer matrix composites (PMC's) during exposure on LDEF. In an effort to minimize fragmentation, material was removed from the sample surfaces by laser desorption and desorbed neutrals were ionized by electron impact. Ions were detected in a time-of-flight mass analyzer which allows the entire mass spectrum to be collected for each laser shot. The method is ideal for these studies because only a small amount of ash is available for analysis. Three sets of samples were studied including C/polysulfone, C/polyimide and C/phenolic. Each set contains leading and trailing edge LDEF samples and their respective controls. In each case, the mass spectrum of the ash shows a number of high mass peaks which can be assigned to fragments of the associated polymer. These high mass peaks are not observed in the spectra of the control samples. In general, the results indicate that the ash is formed from decomposition of the polymer matrix.

Pallix, Joan B.↗

Proximate nutritional composition of CELSS crops grown at different CO2 partial pressures

Two Controlled Ecological Life Support System (CELSS) candidate crops, soybean (Glycine max) and potato (Solanum tuberosum), were grown hydroponically in controlled environments maintained at carbon dioxide (CO2) partial pressures ranging from 0.05 to 1.00 kPa (500 to 10,000 ppm at 101 kPa atmospheric pressure). Plants were harvested at maturity (90 days for soybean and 105 days for potato) and all tissues analyzed for proximate nutritional composition (i.e. protein, fat, carbohydrate, crude fiber, and ash content). Soybean seed ash and crude fiber were higher and carbohydrate was lower than values reported for field-grown seed. Potato tubers showed little difference from field-grown tubers. Crude fiber of soybean stems and leaves increased with increased CO2, as did soybean leaf protein (total nitrogen). Potato leaf and stem (combined) protein levels also increased with increased CO2, while leaf and stem carbohydrates decreased. Values for leaf and stem protein and ash were higher than values generally reported for field-grown plants for both species. Results suggest that CO2 partial pressure should have little influence on proximate composition of potato tubers or soybean seed, but that high ash and protein levels might be expected from leaves and stems of crops grown in controlled environments of a CELSS.

Wheeler, R. M.↗

The Effects of Hypergravity and Adrenalectomy on Bone Mineral Content, Urine Calcium and Body Mass in Rats

The effects of 14 days of increased gravitational load, and the absence of adrenal stress hormones on total body bone mineral content (BMC) were examined in male Sprague-Dawley rats. Centrifugation at 2 Gs (2G) was used to increase the gravitational load, and bilateral adrenalectomy (ADX) was used to eliminate the production of adrenal stress hormones. Stationary groups at 1 G (1G) and sham operated (SHAM) animals served as controls. Thirty rats (n=6 or 8) made up the four experimental groups (1G SHAM, 1G ADX, 2G SHAM and 2G ADX). BMC was assessed by dual energy x-ray absorptiometry (DXA) which was performed to determine the total body bone mineral content, and also through bone ashing of the left femur and the left humerus. Activity was determined through biotelemetry, also body mass and food intake were measured. Multi-factorial analysis of variance (MANCOVA) and Newman Keuls post hoc tests were used to analyze significant effects (p is less than 0.05) for the primary variables. Results from both DXA and the ashed femur indicated that BMC decreased significantly with increased G for both the SHAM and ADX groups. The BMC determined by DXA for the 1G ADX group was also significantly lower than the 1G SHAM group, however the 2G SHAM and 2G ADX groups were not significantly different. However, the bone ashing results showed the femur differed significantly only between the rates of centrifugation and not between the ADX and SHAM. The humerus showed no significant difference between any of the groups. There was a significant decrease in body mass with increased G and there was no ADX effect on body mass. When DXA BMC was normalized for body mass changes, there were no significant group differences. However, with bone ashing, the femur BMC/BW still showed significant difference between rates of centrifugation, with the 2G group being lower. Activity level decreased with body mass, and food intake data showed there was significant hypophagia during the first few days of centrifugation. Urine calcium was measured and was found decrease at the start of centrifugation for the 2G groups and rise to a level higher than that of the stationary groups. Finally, the correlation between BW and BMC was determined to be highly correlated (r = .71). These results suggest that the decrease in total body BMC seen with hypergravity may be based to a large extent on the differences in body mass induced by the 2G load.

Lau, A.↗

Proximate composition of CELSS crops grown in NASA's Biomass Production Chamber

Edible biomass from four crops of wheat (Triticum aestivum L.), four crops of lettuce (Lactuca sativa L.), four crops of potato (Solanum tuberosum L.), and three crops of soybean (Glycine max (L.) Merr.) grown in NASA's CELSS Biomass Production Chamber were analyzed for proximate composition. All plants were grown using recirculating nutrient (hydroponic) film culture with pH and electrical conductivity automatically controlled. Temperature and humidity were controlled to near optimal levels for each species and atmospheric carbon dioxide partial pressures were maintained near 100 Pa during the light cycles. Soybean seed contained the highest percentage of protein and fat, potato tubers and wheat seed contained the highest levels of carbohydrate, and lettuce leaves contained the highest level of ash. Analyses showed values close to data published for field-grown plants with several exceptions: In comparison with field-grown plants, wheat seed had higher protein levels; soybean seed had higher ash and crude fiber levels; and potato tubers and lettuce leaves had higher protein and ash levels. The higher ash and protein levels may have been a result of the continuous supply of nutrients (e.g., potassium and nitrogen) to the plants by the recirculating hydroponic culture.

NASA Discipline Life Support Systems↗

Sewage sludge treatment system

Raw sewage may be presently treated by mixing screened raw sewage with activated carbon. The mixture is then allowed to stand in a first tank for a period required to settle the suspended matter to the bottom of the tank as a sludge. Thereafter, the remaining liquid is again mixed with activated carbon and the mixture is transferred to a secondary settling tank, where it is permitted to stand for a period required for the remaining floating material to settle as sludge and for adsorption of sewage carbon as well as other impurities to take place. The sludge from the bottom of both tanks is removed and pyrolyzed to form activated carbon and ash, which is mixed with the incoming raw sewage and also mixed with the liquid being transferred from the primary to the secondary settling tank. It has been found that the output obtained by the pyrolysis process contains an excess amount of ash. Removal of this excess amount of ash usually also results in removing an excess amount of carbon thereby requiring adding carbon to maintain the treatment process. By separately pyrolyzing the respective sludges from the first and second settling tanks, and returning the separately obtained pyrolyzed material to the respective first and second tanks from which they came, it has been found that the adverse effects of the excessive ash buildup is minimized, the carbon yield is increased, and the sludge from the secondary tank can be pyrolyzed into activated carbon to be used as indicated many more times than was done before exhaustion occurs.

Kalvinskas, John J.↗

Eyjafjallajokull Volcano Plume Particle-Type Characterization from Space-Based Multi-angle Imaging

The Multi-angle Imaging SpectroRadiometer (MISR) Research Aerosol algorithm makes it possible to study individual aerosol plumes in considerable detail. From the MISR data for two optically thick, near-source plumes from the spring 2010 eruption of the Eyjafjallaj kull volcano, we map aerosol optical depth (AOD) gradients and changing aerosol particle types with this algorithm; several days downwind, we identify the occurrence of volcanic ash particles and retrieve AOD, demonstrating the extent and the limits of ash detection and mapping capability with the multi-angle, multi-spectral imaging data. Retrieved volcanic plume AOD and particle microphysical properties are distinct from background values near-source, as well as for overwater cases several days downwind. The results also provide some indication that as they evolve, plume particles brighten, and average particle size decreases. Such detailed mapping offers context for suborbital plume observations having much more limited sampling. The MISR Standard aerosol product identified similar trends in plume properties as the Research algorithm, though with much smaller differences compared to background, and it does not resolve plume structure. Better optical analogs of non-spherical volcanic ash, and coincident suborbital data to validate the satellite retrieval results, are the factors most important for further advancing the remote sensing of volcanic ash plumes from space.

Kahn, Ralph A.↗

Predicting Bone Mechanical State During Recovery After Long-Duration Skeletal Unloading Using QCT and Finite Element Modeling

During long-duration missions at the International Space Station, astronauts experience weightlessness leading to skeletal unloading. Unloading causes a lack of a mechanical stimulus that triggers bone cellular units to remove mass from the skeleton. A mathematical system of the cellular dynamics predicts theoretical changes to volume fractions and ash fraction in response to temporal variations in skeletal loading. No current model uses image technology to gather information about a skeletal site s initial properties to calculate bone remodeling changes and then to compare predicted bone strengths with the initial strength. The goal of this study is to use quantitative computed tomography (QCT) in conjunction with a computational model of the bone remodeling process to establish initial bone properties to predict changes in bone mechanics during bone loss and recovery with finite element (FE) modeling. Input parameters for the remodeling model include bone volume fraction and ash fraction, which are both computed from the QCT images. A non-destructive approach to measure ash fraction is also derived. Voxel-based finite element models (FEM) created from QCTs provide initial evaluation of bone strength. Bone volume fraction and ash fraction outputs from the computational model predict changes to the elastic modulus of bone via a two-parameter equation. The modulus captures the effect of bone remodeling and functions as the key to evaluate of changes in strength. Application of this time-dependent modulus to FEMs and composite beam theory enables an assessment of bone mechanics during recovery. Prediction of bone strength is not only important for astronauts, but is also pertinent to millions of patients with osteoporosis and low bone density.

Chang, Katarina L.↗

The 2019 Raikoke volcanic eruption -Part 2: Particle-phase dispersion and concurrent wildfire smoke emissions

Between 27 June and 14 July 2019 aerosol layers were observed by the United Kingdom (UK) Raman lidar network in the upper troposphere and lower stratosphere. The arrival of these aerosol layers in late June caused some concern within the London Volcanic Ash Advisory Centre (VAAC) as according to dispersion simulations the volcanic plume from the 21 June 2019 eruption of Raikoke was not expected over the UK until early July. Using dispersion simulations from the Met Office Numerical Atmospheric-dispersion Modelling Environment (NAME), and supporting evidence from satellite and in situ aircraft observations, we show that the early arrival of the stratospheric layers was not due to aerosols from the explosive eruption of the Raikoke volcano but due to biomass burning smoke aerosols associated with intense forest fires in Alberta, Canada, that occurred 4 d prior to the Raikoke eruption. We use the observations and model simulations to describe the dispersion of both the volcanic and forest fire aerosol clouds and estimate that the initial Raikoke ash aerosol cloud contained around 15 Tg of volcanic ash and that the forest fires produced around 0.2 Tg of biomass burning aerosol. The operational monitoring of volcanic aerosol clouds is a vital capability in terms of aviation safety and the synergy of NAME dispersion simulations, and lidar data with depolarising capabilities allowed scientists at the Met Office to interpret the various aerosol layers over the UK and attribute the material to their sources. The use of NAME allowed the identification of the observed stratospheric layers that reached the UK on 27 June as biomass burning aerosol, characterised by a particle linear depolarisation ratio of 9 %, whereas with the lidar alone the latter could have been identified as the early arrival of a volcanic ash–sulfate mixed aerosol cloud. In the case under study, given the low concentration estimates, the exact identification of the aerosol layers would have made little substantive difference to the decision-making process within the London VAAC. However, our work shows how the use of dispersion modelling together with multiple observation sources enabled us to create a more complete description of atmospheric aerosol loading.

Martin J Osborne↗

Real Time Volcanic Cloud Products and Predictions for Aviation Alerts

Volcanic eruptions can inject significant amounts of sulfur dioxide (SO2) and volcanic ash into the atmosphere, posing a substantial risk to aviation safety. Ingesting near-real time and Direct Readout satellite volcanic cloud data is vital for improving reliability of volcanic ash forecasts and mitigating the effects of volcanic eruptions on aviation and the economy. NASA volcanic products from the Ozone Monitoring Insrument (OMI) aboard the Aura satellite have been incorporated into Decision Support Systems of many operational agencies. With the Aura mission approaching its 10th anniversary, there is an urgent need to replace OMI data with those from the next generation operational NASA/NOAA Suomi National Polar Partnership (SNPP) satellite. The data provided from these instruments are being incorporated into forecasting models to provide quantitative ash forecasts for air traffic management. This study demonstrates the feasibility of the volcanic near-real time and Direct Readout data products from the new Ozone Monitoring and Profiling Suite (OMPS) ultraviolet sensor onboard SNPP for monitoring and forecasting volcanic clouds. The transition of NASA data production to our operational partners is outlined. Satellite observations are used to constrain volcanic cloud simulations and improve estimates of eruption parameters, resulting in more accurate forecasts. This is demonstrated for the 2012 eruption of Copahue. Volcanic eruptions are modeled using the Goddard Earth Observing System, Version 5 (GEOS-5) and the Goddard Chemistry Aerosol and Radiation Transport (GOCART) model. A hindcast of the disruptive eruption from Iceland's Eyjafjallajokull is used to estimate aviation re-routing costs using Metron Aviation's ATM Tools.

Volcanic ash↗

VIPR III VADR SPIDER Structural Design and Analysis

In support of the National Aeronautics and Space Administration (NASA) Vehicle Integrated Propulsion Research (VIPR) Phase III team to evaluate the volcanic ash environment effects on the Pratt & Whitney F117-PW-100 turbofan engine, NASA Armstrong Flight Research Center has successfully performed structural design and analysis on the Volcanic Ash Distribution Rig (VADR) and the Structural Particulate Integration Device for Engine Research (SPIDER) for the ash ingestion test. Static and dynamic load analyses were performed to ensure no structural failure would occur during the test. Modal analysis was conducted, and the results were used to develop engine power setting avoidance zones. These engine power setting avoidance zones were defined to minimize the dwell time when the natural frequencies of the VADR/SPIDER system coincided with the excitation frequencies of the engine which was operating at various revolutions per minute. Vortex-induced vibration due to engine suction air flow during the ingestion test was also evaluated, but was not a concern.

VADR SPIDER↗

Volcanic Eruption of Cumbre Vieja, La Palma, Spain: A First Insight to the Particulate Matter Injected in the Troposphere

The volcanic eruption of Cumbre Vieja (La Palma Island, Spain), started on 19 September, 2021, and was declared terminated on 25 December, 2021. A complete set of aerosol measurements were deployed around the volcano within the first month of the eruptive activity. This paper describes the results of the observations made at Tazacorte on the west bank of the island where a polarized micro pulse lidar was deployed. The two and a half months analyzed (16 October – 31 December) reveal that the peak height of the lowermost and strongest volcanic plume did not exceed 3 km (mean of 1.43±0.45 km over the whole period) and was highly variable. It steadily increased until week 11 after the eruption start (and 3 weeks before its end) and started decreasing afterwards. The ash mass concentration has been assessed with a method based on the polarization capability of the instrument. Considering the limitation of current remote sensing techniques to detect large to giant particles, the ash mass concentration on one of the days with the highest ash load is estimated to have peaked in the range 800-3200 μg m(exp -3) in the lowermost layer below 2.5 km.

Cumbre Vieja↗

A proposed origin of the Olympus Mons escarpment

Olympus Mons (Nix Olympica) on Mars is delimited by a unique steep, nearly circular scarp. A pyroclastic model is proposed for the construct's origin. It is postulated that the Olympus Mons plateau is constructed predominantly of numerous ash-flow tuffs which were erupted from central sources over an extended period of time. Lava flows may be intercalated with the tuffs. A schematic radial profile incorporating the inferred compaction zones for an ash sheet is proposed. Following emplacement, eolian (and possibly fluvial) erosion and abrasion during dust storms would act on the ash sheets. Interior portions of the sheets would spall and slump following eolian erosion, generating steep, relatively smooth boundary scarps. The scarp would be circular due to symmetrical distribution of compaction zones. The model implies further that the Olympus Mons plateau rests on a more resistant rock substrate.

King, J. S.↗