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Improving Bone-Health Monitoring in Astronauts: Recommended Use of Quantitative Computed Tomography [QCT] for Clinical and Operational Decisions by NASA

DXA measurement of areal bone mineral density [aBMD,g/cm2] is required by NASA for assessing skeletal integrity in astronauts. Due to the abundance of population-based data that correlate hip and spine BMDs to fragility fractures, BMD is widely applied as a predictor of fractures in the general aging population. In contrast, QCT is primarily a research technology that measures three-dimensional , volumetric BMD (vBMD,mg/cm3) of bone and is therefore capable of differentiating between cortical and trabecular components. Additionally, when combined with Finite Element Modeling [FEM], a computational tool, QCT data can be used to estimate the whole bone strength of the hip [FE strength] for a specific load vector. A recent report demonstrated that aBMD failed to correlate with incurred changes in FE strength (for fall and stance loading) by astronauts over typical 180-day ISS (International Space Station) missions. While there are no current guidelines for using QCT data in clinical practice, QCT increases the understanding of how bone structure and mineral content are affected by spaceflight and recovery on Earth. In order to understand/promote/consider the use of QCT, NASA convened a panel of clinicians specializing in osteoporosis. After reviewing the available, albeit limited, medical and research information from long-duration astronauts (e.g., data from DXA, QCT, FEM, biochemistry analyses, medical records and in-flight exercise performance) the panelists were charged with recommending how current and future research data and analyses could inform clinical and operational decisions. The Panel recommended that clinical bone tests on astronauts should include QCT (hip and lumbar spine) for occupational risk surveillance and for the estimation of whole hip bone strength as derived by FEM. FE strength will provide an improved index that NASA could use to select astronauts of optimal bone health for extended duration missions, for repeat missions or for specific mission operations.

Sibonga, J. D.↗

Analysis of the request patterns to the NSSDC on-line archive

NASA missions, both for earth science and for space science, collect huge amounts of data, and the rate at which data is being gathered is increasing. For example, the EOSDIS project is expected to collect petabytes per year. In addition, these archives are being made available to remote users over the Internet. The ability to manage the growth of the size and request activity of scientific archives depends on an understanding of the access patterns of scientific users. The National Space Science Data Center (NSSDC) of NASA Goddard Space Flight Center has run their on-line mass storage archive of space data, the National Data Archive and Distribution Service (NDADS), since November 1991. A large world-wide space research community makes use of NSSDC, requesting more than 20,000 files per month. Since the initiation of their service, they have maintained log files which record all accesses the archive. In this report, we present an analysis of the NDADS log files. We analyze the log files, and discuss several issues, including caching, reference patterns, clustering, and system loading.

Johnson, Theodore↗

ISS Stage 12A Post-Flight Modal Analysis, Model Validation and Correlation

This paper summarizes the on-orbit structural dynamic data and the related modal analysis, model validation and correlation performed for the ISS configurations spanning ISS Stage 12A. The objective of this analysis is to validate and correlate analytical models used to verify the ISS critical interface dynamic loads and improve its fatigue life prediction. On-Orbit dynamic responses were measured during the ISS configurations throughout ISS Stage 12A by the two main ISS instrumentation systems; Internal Wireless Instrumentation System (IWIS) and the Structural Dynamic Measurement System (SDMS). These nominal on-orbit events include Russian vehicle docking and undockings. Also, the ISS photogrammetric system recorded the movements of the 2A and 4A solar arrays during a modified ISS maneuver. Modal analyses were performed on the measured data to extract modal parameters including frequency, damping and mode shapes. Correlation and comparisons between the test and analytical frequencies and mode shapes were performed to assess the accuracy of the analytical models for the ISS configurations under consideration.

Fitzpatrick, Kristin↗

Calibration of strain-gage installations in aircraft structures for the measurement of flight loads

A general method has been developed for calibrating strain-gage installations in aircraft structures, which permits the measurement in flight of the shear or lift, the bending moment, and the torque or pitching moment on the principal lifting or control surfaces. Although the stress in structural members may not be a simple function of the three loads of interest, a straightforward procedure is given for numerically combining the outputs of several bridges in such a way that the loads may be obtained. Extensions of the basic procedure by means of electrical combination of the strain-gage bridges are described which permit compromises between strain-gage installation time, availability of recording instruments, and data reduction time. The basic principles of strain-gage calibration procedures are illustrated by reference to the data for two aircraft structures of typical construction, one a straight and the other a swept horizontal stabilizer.

Skopinski, T H↗

Increased Treadmill Running and Lower-Body Resistance Training Intensity May Attenuate Aerobic Capacity Loss During Spaceflight

BACKGROUND: In-flight exercise training is the primary countermeasure to mitigate spaceflight-induced decrements in strength and aerobic capacity. Despite high-quality exercise capabilities and prescriptions aboard the International Space Station (ISS), most astronauts experience strength and aerobic capacity loss; however, significant individual variability exists. Recent findings suggest that greater in-flight running (i.e., distance per session) and lower-body resistance exercise intensity (i.e., load relative to body weight) help preserve strength. Whether similar variables contribute to the preservation of aerobic capacity during spaceflight is unknown. METHODS: A NASA database of exercise performance metrics was used to identify long-duration (≥ 90 days) ISS crew who completed pre- and post-flight aerobic capacity testing (VO2peak, cycle ergometry, n = 44). “Responders” (R) were classified as those that maintained or improved VO2peak (n = 13; 1.4 ± 3.3%), and “non-responders” (NR) were those with the most severe decrements (n = 13; -20.0 ± 3.4%) from pre- to post-flight. In-flight exercise records (cycling, treadmill, resistance exercise) were aggregated across flight weeks. Independent t-tests or Mann-Whitney U tests were used to compare training variables (i.e., frequency, time, intensity, volume) between R and NR. RESULTS: Consistent with the variables contributing to strength protection, in-flight running distance (R: 5.0 ± 0.7; NR: 4.2 ± 1.0 km/session, p = 0.020) and lower-body resistance exercise intensity (R: 110.9 ± 27.3; NR: 91.7 ± 16.5% body weight, p = 0.040) were greater in R than NR. Active running time was also greater in R than NR (R: 101.1 ± 20.4; NR: 82.3 ± 23.5 min/wk; p = 0.039). However, no group differences in cycling frequency, intensity, or time, as well as upper body or core resistance exercise intensity, volume, or frequency were observed. CONCLUSIONS: Although physiologically distinct stimuli, the exercise training variables contributing to the preservation of both strength and aerobic capacity during microgravity exposure appear to be consistent. Increased running time and distance, but not cycling, combined with higher-intensity lower-body resistance exercise, may help mitigate losses in both aerobic capacity and strength during long-duration spaceflight.

Alyssa N Varanoske↗

Features Of Cavity Flow And Acoustics Of Stratospheric Observatory For Infrared Astronomy

The stratospheric observatory for infrared astronomy (SOFIA) is a 2.5 meter aperture Cassegrain telescope with a Nasmyth focus that will be housed in an open cavity in the Boeing 747-SP aircraft and operated at altitudes around 41,000 feet for infrared (IR) viewing of celestial events of astronomical nature. At these altitudes the IR viewing capability of SOFIA far exceeds that of any ground based system. To minimize IR transmission losses, SOFIA will operate with an open cavity. Such an open cavity during flight creates several challenging aerodynamic and aeroacoustic design problems. Foremost of these are: the shear layer over the cavity may cause unwanted resonance if the cavity is untreated; this might give rise to excessive sound pressure levels (SPL) in the cavity and thus affect the unsteady loads on the telescope; the unsteady flow within the cavity produces large dynamic loads and moments that will impact the pointing accuracy of the telescope; the open cavity and the shear layer control devices produce additional drag that will affect directly the time of flight of the mission; the aft location of the cavity down stream of port wing will affect the the flow on the aircraft control surfaces and thus the stability of the aircraft. Also, the highly turbulent shear layer over the cavity and the temperature gradients and 'hot spots' within the cavity can produce a wave front error of the image when it reaches the focal plane of the recorder.

Srinivasan, G. R.↗

Extraction of Modal Parameters from Spacecraft Flight Data

The modeled response of spacecraft systems must be validated using flight data as ground tests cannot adequately represent the flight. Tools from the field of operational modal analysis would typically be brought to bear on such structures. However, spacecraft systems have several complicated issues: 1. High amplitudes of loads; 2. Compressive loads on the vehicle in flight; 3. Lack of generous time-synchronized flight data; 4. Changing properties during the flight; and 5. Major vehicle changes due to staging. A particularly vexing parameter to extract is modal damping. Damping estimation has become a more critical issue as new mass-driven vehicle designs seek to use the highest damping value possible. The paper will focus on recent efforts to utilize spacecraft flight data to extract system parameters, with a special interest on modal damping. This work utilizes the analysis of correlation functions derived from a sliding window technique applied to the time record. Four different case studies are reported in the sequence that drove the authors understanding. The insights derived from these four exercises are preliminary conclusions for the general state-of-the-art, but may be of specific utility to similar problems approached with similar tools.

James, George H.↗

Results of the 1973 NASA/JPL balloon flight solar cell calibration program

High altitude balloon flights carried 37 standard solar cells for calibration above 99.5 percent of the earth's atmosphere. The cells were assembled into standard modules with appropriate resistors to load each cell at short circuit current. Each standardized module was mounted at the apex of the balloon on a sun tracker which automatically maintained normal incidence to the sun within 1.0 deg. The balloons were launched to reach a float altitude of approximately 36.6 km two hours before solar noon and remain at float altitude for two hours beyond solar noon. Telemetered calibration data on each standard solar cell was collected and recorded on magnetic tape. At the end of each float period the solar cell payload was separated from the balloon by radio command and descended via parachute to a ground recovery crew. Standard solar cells calibrated and recovered in this manner are used as primary intensity reference standards in solar simulators and in terrestrial sunlight for evaluating the performance of other solar cells and solar arrays with similar spectral response characteristics.

Yasui, R. K.↗

Development and Implementation of a Hardware In-the-Loop Test Bed for Unmanned Aerial Vehicle Control Algorithms

Successful prediction and management of battery life using prognostic algorithms through ground and flight tests is important for performance evaluation of electrical systems. This paper details the design of test beds suitable for replicating loading profiles that would be encountered in deployed electrical systems. The test bed data will be used to develop and validate prognostic algorithms for predicting battery discharge time and battery failure time. Online battery prognostic algorithms will enable health management strategies. The platform used for algorithm demonstration is the EDGE 540T electric unmanned aerial vehicle (UAV). The fully designed test beds developed and detailed in this paper can be used to conduct battery life tests by controlling current and recording voltage and temperature to develop a model that makes a prediction of end-of-charge and end-of-life of the system based on rapid state of health (SOH) assessment.

Battery Testbed↗

Acoustic pressures on a prop-fan aircraft fuselage surface

Acoustic pressure amplitude and phase distributions on the surface of a simulated fuselage (a rigid semi-cylinder) installed in an acoustically treated wind tunnel near a Prop-Fan model were measured. The test conditions simulated the relative tip Mach number and blade loading of a full scale Prop-Fan at high altitude 0.8 Mach number cruise. Measurements were also made at equivalent microphone locations without the semi-cylinder to establish the effects of the presence of a fuselage on the sound pressure amplitudes. These effects were found to be 6 dB at 90 degrees incidence, decreasing to no effect at grazing incidence. Comparison of measurements and calculations using a Hamilton Standard Prop-Fan noise calculation computer program showed good agreement in peak level and in phase distribution. Continuous recordings were also made of a Prop-Fan RPM sweep at constant simulated flight speed and a simulated flight speed sweep at constant Prop-Fan RPM. These showed smooth variations in noise level over the tip Mach number range 0.878 to 1.143.

Magliozzi, B.↗

Accelerometer design

In connection with the development of an accelerometer for measuring the loads on airplanes in free flight a study of the theory of such instruments has been made, and the results of this study are summarized in this report. A portion of the analysis deals particularly with the sources of error and with the limitations placed on the location of the instrument in the airplane. The discussion of the dynamics of the accelerometer includes a study of its theoretical motions and of the way in which they are affected by the natural period of vibration and by the damping, together with a report of some experiments on the effect of forced vibrations on the record.

Norton, F H↗

Validation of an Automated System for Arrival Traffic Management

The fuel-efficiencies of arrival flights that were managed by an automated system were compared to the fuel-efficiencies of arrival flights that were managed by air traffic controllers. It was infeasible to have the automated system control arrivals in real operations, so the comparison was accomplished by setting up a fast-time simulation where the automated system could manage arrivals with the same initial conditions and flight plans as those that operated in real operations during a selected comparison period and in the same background traffic. For this study, Newark Liberty International Airport was selected as the arrival airport because its high traffic load and constrained arrival procedures were expected to highlight fuel-efficiency benefits of an automated system. In the simulation, the automated system managed Newark arrivals, and the other flights (arrivals to other airports, departures, and overflights) composed the background traffic. To match the simulation and the real operations background traffic, the other flights flew in simulation the same trajectory that they flew in real operations during the comparison period. Fuel-efficiency was measured by calculating fuel burns of the arrival trajectories. The fuel-efficiencies of arrival trajectories produced in the simulation were compared with the estimated fuel-efficiencies of arrival trajectories recorded from real operations during the comparison period. Results showed that automation managed arrivals burned 346 lbs less fuel per flight on average than controller managed arrivals.

air traffic control↗

Validation of an Automated System for Arrival Traffic Management

The fuel-efficiencies of arrival flights that were managed by an automated system were compared to the fuel-efficiencies of arrival flights that were managed by air traffic controllers. It was infeasible to have the automated system control arrivals in real operations, so the comparison was accomplished by setting up a fast-time simulation where the automated system could manage arrivals with the same initial conditions and flight plans as those that operated in real operations during a selected comparison period and in the same background traffic. For this study, Newark Liberty International Airport was selected as the arrival airport because its high traffic load and constrained arrival procedures were expected to highlight fuel-efficiency benefits of an automated system. In the simulation, the automated system managed Newark arrivals, and the other flights (arrivals to other airports, departures, and overflights) composed the background traffic. To match the simulation and the real operations background traffic, the other flights flew in simulation the same trajectory that they flew in real operations during the comparison period. Fuel-efficiency was measured by calculating fuel burns of the arrival trajectories. The fuel-efficiencies of arrival trajectories produced in the simulation were compared with the estimated fuel-efficiencies of arrival trajectories recorded from real operations during the comparison period. Results showed that automation managed arrivals burned 346 lbs less fuel per flight on average than controller managed arrivals.

air traffic control↗

Further development and flight test of an autonomous precision landing system using a parafoil

NASA Dryden Flight Research Center and NASA Johnson Space Center are jointly conducting a phased program to determine the feasibility of the autonomous recovery of a spacecraft using a ram-air parafoil system for the final stages of entry from space to a precision landing. The feasibility is being studied using a flight model of a spacecraft in the generic shape of a flattened biconic that weighs approximately 120 lb and is flown under a commercially available ram-air parafoil. Key components of the vehicle include the global positioning system (GPS) guidance for navigation, a flight control computer, an electronic compass, a yaw rate gyro, and an onboard data recorder. A flight test program is being used to develop and refine the vehicle. The primary flight goal is to demonstrate autonomous flight from an altitude of 3,000 m (10,000 ft) with a lateral offset of 1.6 km (1.0 mi) to a precision soft landing. This paper summarizes the progress to date. Much of the navigation system has been tested, including a heading tracker that was developed using parameter estimation techniques and a complementary filter. The autoland portion of the autopilot is still in development. The feasibility of conducting the flare maneuver without servoactuators was investigated as a means of significantly reducing the servoactuator rate and load requirements.

Murray, James E.↗

Results from the Space Shuttle STS-95 Electronic Nose Experiment

A miniature electronic nose in which the sensing media are insulating polymers loaded with carbon black as a conductive medium has been designed and built at the Jet Propulsion Laboratory. The ENose has a volume of 1700 cc, weighs 1.4 kg including the operating computer, and uses 1.5 W average power (3 W peak power). This ENose was used in a demonstration experiment aboard STS-95 (October, 1998), in which the ENose was operated continuously for six days and recorded the sensors' response to the air in the middeck. The ENose was designed to detect ten common contaminants in space shuttle crew quarters air. The experiment was controlled by collecting air samples daily and analyzing them using standard analytical techniques after the flight. Changes in humidity were detected and quantified, neither the ENose nor the air samples detected any of the contaminants on the target list. The device is microgravity insensitive.

Ryan, M. A.↗

Comparison of Anthropomorphic Test Device and Human Volunteer Responses in Simulated Landing Impact Tests of U.S. Space Vehicles

United States (U.S.) crewed vehicles are being designed to support the National Aeronautics and Space Administration’s (NASA’s) human spaceflight programs. Vehicles must be designed to meet NASA’s occupant protection requirements including landing injury assessment with anthropomorphic test devices (ATDs) and analytical models. However, these tools are limited in capturing all injuries that might occur during spacecraft landings. A NASA study of injuries during Soyuz vehicle landings has shown that analytical models are underpredicting occupant injury. Because of the inherent limitations with our analytical tools, human volunteer impact testing was employed to assess flight-like landing conditions of U.S. crewed vehicles. A total of 84 human volunteer tests in 11 different test orientations and g-levels were completed as part of this effort in collaboration with the Air Force Research Laboratory (AFRL) at Wright-Patterson Air Force Base and U.S. vehicle development companies. Human subjects were tested at various realistic landing loads and in the highest fidelity seat and suit components that were available at the time of testing for two U.S. vehicles. Matched-pair ATD tests in the same test conditions were also conducted with small female and midsized male Hybrid III ATDs. ATDs were fully instrumented. Head accelerations and subjective responses were recorded for human subjects. In some cases, chest accelerations were captured. Responses of the ATDs and humans in matched-pair tests were compared. No ATD tests showed evidence for risk of injury based on NASA occupant protection requirements. Human subjects reported 17 cases of discomfort or pain, and 1 human subject was diagnosed with a minor injury that was not evident in the ATD tests. These results provide evidence that ATDs do not capture all potential injury risks, namely lower severity injuries, discomfort, pain, and fit issues. Overall, human testing is beneficial to understanding the true risk of injury to crewmembers during Earth landings.

Teresa M Reiber↗

Comparison of Anthropomorphic Test Device and Human Volunteer Responses in Simulated Landing Impact Tests of U.S. Space Vehicles

United States (U.S.) crewed vehicles are being designed to support the National Aeronautics and Space Administration’s (NASA’s) human spaceflight programs. Vehicles must be designed to meet NASA’s occupant protection requirements including landing injury assessment with anthropomorphic test devices (ATDs) and analytical models. However, these tools are limited in capturing all injuries that might occur during spacecraft landings. A NASA study of injuries during Soyuz vehicle landings has shown that analytical models are underpredicting occupant injury. Because of the inherent limitations with our analytical tools, human volunteer impact testing was employed to assess flight-like landing conditions of U.S. crewed vehicles. A total of 84 human volunteer tests in 11 different test orientations and g-levels were completed as part of this effort in collaboration with the Air Force Research Laboratory (AFRL) at Wright-Patterson Air Force Base and U.S. vehicle development companies. Human subjects were tested at various realistic landing loads and in the highest fidelity seat and suit components that were available at the time of testing for two U.S. vehicles. Matched-pair ATD tests in the same test conditions were also conducted with small female and midsized male Hybrid III ATDs. ATDs were fully instrumented. Head accelerations and subjective responses were recorded for human subjects. In some cases, chest accelerations were captured. Responses of the ATDs and humans in matched-pair tests were compared. No ATD tests showed evidence for risk of injury based on NASA occupant protection requirements. Human subjects reported 17 cases of discomfort or pain, and 1 human subject was diagnosed with a minor injury that was not evident in the ATD tests. These results provide evidence that ATDs do not capture all potential injury risks, namely lower severity injuries, discomfort, pain, and fit issues. Overall, human testing is beneficial to understanding the true risk of injury to crewmembers during Earth landings.

Teresa M Reiber↗

Comparison of Anthropomorphic Test Device and Human Volunteer Responses in Simulated Landing Impact Tests of U.S. Space Vehicles

United States (U.S.) crewed vehicles are being designed to support the National Aeronautics and Space Administration’s (NASA’s) human spaceflight programs. Vehicles must be designed to meet NASA’s occupant protection requirements including landing injury assessment with anthropomorphic test devices (ATDs) and analytical models. However, these tools are limited in capturing all injuries that might occur during spacecraft landings. A NASA study of injuries during Soyuz vehicle landings has shown that analytical models are underpredicting occupant injury. Because of the inherent limitations with our analytical tools, human volunteer impact testing was employed to assess flight-like landing conditions of U.S. crewed vehicles. A total of 84 human volunteer tests in 11 different test orientations and g-levels were completed as part of this effort in collaboration with the Air Force Research Laboratory (AFRL) at Wright-Patterson Air Force Base and U.S. vehicle development companies. Human subjects were tested at various realistic landing loads and in the highest fidelity seat and suit components that were available at the time of testing for two U.S. vehicles. Matched-pair ATD tests in the same test conditions were also conducted with small female and midsized male Hybrid III ATDs. ATDs were fully instrumented. Head accelerations and subjective responses were recorded for human subjects. In some cases, chest accelerations were captured. Responses of the ATDs and humans in matched-pair tests were compared. No ATD tests showed evidence for risk of injury based on NASA occupant protection requirements. Human subjects reported 17 cases of discomfort or pain, and 1 human subject was diagnosed with a minor injury that was not evident in the ATD tests. These results provide evidence that ATDs do not capture all potential injury risks, namely lower severity injuries, discomfort, pain, and fit issues. Overall, human testing is beneficial to understanding the true risk of injury to crewmembers during Earth landings.

Teresa M Reiber↗