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At least 109 records · Page 6

Integrated Evaluation of Latent Viral Reactivation During Spaceflight

This application proposes a continuation of our current effort, which has provided the first demonstration of viral reactivation during space flight. We have used the herpesvirus EBV as a model for latent viral reactivation and have shown that increased amounts of EBV DNA were shed by astronauts during space flight. Analysis of the Antarctic space flight analog indicated that the frequency of viral shedding may also increase (along with the increased numbers of virus) during long periods of isolation. However, a number of critical questions remain before the findings may be considered a significant health risk during extended space flight. These include: Are other latent viruses (e.g., other herpesviruses and polyornaviruses) in addition to EBV also reactivated and shed more frequently and/or in higher numbers during space flight? Is the viral reactivation observed in space flight and ground-based analogs mediated through the hypothalamus-pituitary-adrenal (HPA) axis resulting in a decreased cell-mediated immune response? How does detection of viral DNA by PCR analysis correlate with infectious virus? How does the amount of virus found during flight compare with viral levels observed in acute/chronic viral illnesses and in control individuals? This expanded study will examine the phenomenon of viral reactivation from the initiating stress through the HPA axis with the accompanying suppression of the immune system resulting in viral reactivation. This information is essential to determine if latent viral reactivation among crewmembers represents a sufficient medical risk to space travel to require the development of suitable countermeasures.

Pierson, Duane L.↗

The Estimation of Surface Latent Heat Flux over the Ocean and its Relationship to Marine Atmospheric Boundary Layer (MABL) Structure

A new technique combining active and passive remote sensing instruments for the estimation of surface latent heat flux over the ocean is presented. This synergistic method utilizes aerosol lidar backscatter data, multi-channel infrared radiometer data, and microwave scatterometer data acquired onboard the NASA P-313 research aircraft during an extended field campaign over the Atlantic ocean in support of the Lidar In-space Technology Experiment (LITE) in September of 1994. The 10 meter wind speed derived from scatterometers and lidar-radiometer inferred near-surface moisture are used to obtain an estimate of the surface flux of moisture via a bulk aerodynamic formula. The results are compared with the Special Sensor Microwave Imager (SSM/I) daily average latent heat flux and show reasonable agreement. However, the SSM/I values are biased low by about 15 W/sq m. In addition, the Marine Atmospheric Boundary Layer (MABL) height, entrainment zone thickness and integrated lidar backscatter intensity are computed from the lidar data and compared with the magnitude of the surface fluxes. The results show that the surface latent heat flux is most strongly correlated with entrainment zone depth, MABL height and the integrated MABL lidar backscatter, with corresponding correlation coefficients of 0.39, 0.43 and 0.71, respectively.

Palm, Stephen P.↗

Maintaining the Body's Immune System: Incidence of Latent Virus Shedding During Space Flight

Your body protects you from illness with its own security system - the immune system. This system keeps illness at bay not only by mounting a defense against foreign organisms, but also by controlling the population of bacteria and viruses that normally live in your body. But there's no need to panic: certain microbes can actually exist in your body without causing illness. Some bacteria are even beneficial - like the E. coli in the large intestine that are an important source of vitamin K. While viruses are not exactly considered beneficial, they can also inhabit the human body without causing immediate harm or infection. A good example is the herpes simplex virus type 1 (HSV1), more commonly known as cold sores or fever blisters. This virus infects 70 to 80 percent of all adults but remains latent much of the time. While latent, the virus within cells remains dormant. Activation of the dormant virus causes it to make copies of itself (known as replication) constantly detectable in body fluids such as urine or saliva in a process called shedding. When a person becomes sick or stressed, however, this weakened condition allows the virus to reactivate and multiply. These elevated levels may be enough to produce symptoms, but shedding can also occur without symptoms. This ability to shed without showing signs of infection, or asymptomatic shedding, is of great interest, as it increases the chances of infecting others. The stresses associated with space flight - adapting to microgravity, isolation from family and friends, living and working in a confined space, sleep deprivation, and busy schedules, to name but a few - may weaken astronauts' immune systems, leaving them at greater risk of viral reactivation. Members of the STS-107 crew will participate in this experiment, Incidence of Latent Viral Shedding in Space Flight, to help scientists understand how reactivation works in space, and at what level replication reaches before symptoms begin to show. This study also promises more insight into the behavior of the larger virus family, herpesvirus, which will help us understand how to prevent infection in populations on Earth and reactivation in those already infected.

Pierson, Duane↗

Intercomparison of Latent Heat Fluxes Over Global Oceans

Turbulent fluxes of momentum, moisture, and heat at the air-sea interface are essential for climate studies. Version 2 Goddard Satellite-based Surface Turbulent Fluxes (GSSTF2) has been derived from the Special Sensor Microwave/Imager (SSM/I) radiance measurements. This dataset, covering the period July 1987-December 2000 over global oceans, has a spatial resolution of 1 deg x 1 deg lat-long and a temporal resolution of 1 day. Turbulent fluxes are derived from the SSM/I surface winds and surface air humidity, as well as the 2-m air and sea surface temperatures (SST) of the NCEP/NCAR reanalysis, using a bulk aerodynamic algorithm based on the surface layer similarity theory. The GSSTF2 bulk flux model, and retrieved daily wind stress, latent heat flux, wind speed, and surface air humidity validate well with ship observations of ten field experiments over the tropical and midlatitude oceans during 1991-99. The global distributions of 1988-2000 annual- and seasonal-mean turbulent fluxes show reasonable patterns related to the atmospheric general circulation and seasonal variations. Latent heat fluxes and related input parameters over global oceans during 1992-93 have been compared among GSSTF1 (version 1), GSSTF2, HOAPS (Hamburg Ocean Atmosphere Parameters and Fluxes from Satellite Data), NCEP/NCAR reanalysis, and one based on COADS (Comprehensive Ocean-Atmosphere Data Set). Our analyses suggest that the GSSTF2 latent heat flux, surface air humidity, surface wind, and SST are quite realistic compared to the other four flux datasets examined. However, significant differences are found among these five flux datasets. The GSSTF2, available at http://daac.gsfc.nasa.gov/CAMPAIGN_DOCS/hydrology/hd_gsstf2.O.html, is useful for climate studies.

Chou, Shu-Hsien↗

Latent Heating Retrieval from TRMM Observations Using a Simplified Thermodynamic Model

A procedure for the retrieval of hydrometeor latent heating from TRMM active and passive observations is presented. The procedure is based on current methods for estimating multiple-species hydrometeor profiles from TRMM observations. The species include: cloud water, cloud ice, rain, and graupel (or snow). A three-dimensional wind field is prescribed based on the retrieved hydrometeor profiles, and, assuming a steady-state, the sources and sinks in the hydrometeor conservation equations are determined. Then, the momentum and thermodynamic equations, in which the heating and cooling are derived from the hydrometeor sources and sinks, are integrated one step forward in time. The hydrometeor sources and sinks are reevaluated based on the new wind field, and the momentum and thermodynamic equations are integrated one more step. The reevalution-integration process is repeated until a steady state is reached. The procedure is tested using cloud model simulations. Cloud-model derived fields are used to synthesize TRMM observations, from which hydrometeor profiles are derived. The procedure is applied to the retrieved hydrometeor profiles, and the latent heating estimates are compared to the actual latent heating produced by the cloud model. Examples of procedure's applications to real TRMM data are also provided.

Grecu, Mircea↗

Immunocytochemical localization of latent transforming growth factor-beta1 activation by stimulated macrophages

Transforming growth factor-beta1 (TGF-beta) is secreted in a latent form consisting of mature TGF-beta noncovalently associated with its amino-terminal propeptide, which is called latency associated peptide (LAP). Biological activity depends upon the release of TGF-beta from the latent complex following extracellular activation, which appears to be the key regulatory mechanism controlling TGF-beta action. We have identified two events associated with latent TGF-beta (LTGF-beta) activation in vivo: increased immunoreactivity of certain antibodies that specifically detect TGF-beta concomitant with decreased immunoreactivity of antibodies to LAP. Macrophages stimulated in vitro with interferon-gamma and lipopolysaccharide reportedly activate LTGF-beta via cell membrane-bound protease activity. We show through dual immunostaining of paraformaldehyde-fixed macrophages that such physiological TGF-beta activation is accompanied by a loss of LAP immunoreactivity with concomitant revelation of TGF-beta epitopes. The induction of TGF-beta immunoreactivity colocalized with immunoreactive betaglycan/RIII in activated macrophages, suggesting that LTGF-beta activation occurs on the cell surface. Confocal microscopy of metabolically active macrophages incubated with antibodies to TGF-beta and betaglycan/RIII prior to fixation supported the localization of activation to the cell surface. The ability to specifically detect and localize LTGF-beta activation provides an important tool for studies of its regulation.

NASA Discipline Radiation Health↗

Interannual and Decadal Variability of Ocean Surface Latent Heat Flux as Seen from Passive Microwave Satellite Algorithms

Ocean surface turbulent fluxes are critical links in the climate system since they mediate energy exchange between the two fluid systems (ocean and atmosphere) whose combined heat transport determines the basic character of Earth's climate. Deriving physically-based latent and sensible heat fluxes from satellite is dependent on inferences of near surface moisture and temperature from coarser layer retrievals or satellite radiances. Uncertainties in these "retrievals" propagate through bulk aerodynamic algorithms, interacting as well with error properties of surface wind speed, also provided by satellite. By systematically evaluating an array of passive microwave satellite algorithms, the SEAFLUX project is providing improved understanding of these errors and finding pathways for reducing or eliminating them. In this study we focus on evaluating the interannual variability of several passive microwave-based estimates of latent heat flux starting from monthly mean gridded data. The algorithms considered range from those based essentially on SSM/I (e.g. HOAPS) to newer approaches that consider additional moisture information from SSM/T-2 or AMSU-B and lower tropospheric temperature data from AMSU-A. On interannual scales, variability arising from ENSO events and time-lagged responses of ocean turbulent and radiative fluxes in other ocean basins (as well as the extratropical Pacific) is widely recognized, but still not well quantified. Locally, these flux anomalies are of order 10-20 W/sq m and present a relevant "target" with which to verify algorithm performance in a climate context. On decadal time scales there is some evidence from reanalyses and remotely-sensed fluxes alike that tropical ocean-averaged latent heat fluxes have increased 5-10 W/sq m since the early 1990s. However, significant uncertainty surrounds this estimate. Our work addresses the origin of these uncertainties and provides statistics on time series of tropical ocean averages, regional space / time correlation analysis, and separation of contributions by variations in wind and near surface humidity deficit. Comparison to variations in reanalysis data sets is also provided for reference.

Robertson, Franklin R.↗

Incidence of Latent Virus Shedding during Space Flight

Measurements of immune parameters of both cellular and innate immunity indicate alterations in immune function in astronauts. Immune changes are due to stress and perhaps other factors associated with launch, flight, and landing phases. Medical relevance of observed changes is not known. The reactivation of latent viruses has been identified as an important in vivo indicator of clinically relevant immune changes. The polymerase chain reaction (PCR) was used to detect the presence of specific viral DNA in body fluids. Initial studies demonstrated Epstein-Barr virus (EBV) reactivation during all 3 mission phases. EBV is shed in saliva following reactivation from B-cells. Incidence of EBV in saliva was higher than control subjects during all 3 mission phases. However, quantitative PCR revealed 10-fold higher levels of EBV DNA present in saliva collected during flight than found in pre- and post flight specimens. To determine if other latent viruses showed similar effects, cytomegalovirus (CMV), another herpes virus, shed in urine following reactivation was studied. A very low incidence (less than 2%) of CMV in urine is found in healthy, lowstressed individuals. However, 25-50% of astronauts shed CMV in their urine before, during, or after flight. Our studies are now focused on varicella-zoster virus (VZV), the etiological agent of chicken-pox during childhood and shingles later in life. We demonstrated reactivation of VZV and shedding of the virus during and after spaceflight in saliva of astronauts with no sign of active infection or symptoms. The maximum shedding of VZV occurred during the flight phase and diminishes rapidly during the first five days after landing. We have utilized the same PCR assay for VZV in a clinical study of shingles patients. Generally, shingles patients shed much more VZV in saliva than astronauts. However, the VZV levels in astronauts overlap with the lower range of VZV numbers in shingles patients. Saliva from shingles patients and astronauts were cultured and infectious VZV was recovered from both groups. We have concluded that multiple latent viruses do reactivate before, during, and after spaceflight and serve as very sensitive indicators for diminished cellular immunity. Future plans will be focused on the clinical risks posed by the reactivation of these viruses. Initial efforts will determine the effect of longer missions on the International Space Station on the reactivation patterns of these viruses.

Mehta, Satish K.↗

MJO Signals in Latent Heating: Results from TRMM Retrievals

The Madden-Julian Oscillation (MJO) is the dominant intraseasonal signal in the global tropical atmosphere. Almost all numerical climate models have difficulty to simulate realistic MJO. Four TRMM datasets of latent heating were diagnosed for signals in the MJO. In all four datasets, vertical structures of latent heating are dominated by two components, one deep with its peak above the melting level and one shallow with its peak below. Profiles of the two components are nearly ubiquitous in longitude, allowing a separation of the vertical and zonal/temporal variations when the latitudinal dependence is not considered. All four datasets exhibit robust MJO spectral signals in the deep component as eastward propagating spectral peaks centered at period of 50 days and zonal wavenumber 1, well distinguished from lower- and higher-frequency power and much stronger than the corresponding westward power. The shallow component shows similar but slightly less robust MJO spectral peaks. MJO signals were further extracted from a combination of band-pass (30 - 90 day) filtered deep and shallow components. Largest amplitudes of both deep and shallow components of the MJO are confined to the Indian and western Pacific Oceans. There is a local minimum in the deep components over the Maritime Continent. The shallow components of the MJO differ substantially among the four TRMM datasets in their detailed zonal distributions in the eastern hemisphere. In composites of the heating evolution through the life cycle of the MJO, the shallow components lead the deep ones in some datasets and at certain longitudes. In many respects, the four TRMM datasets agree well in their deep components, but not in their shallow components and the phase relations between the deep and shallow components. These results indicate that caution must be exercised in applications of these latent heating data.

Zhang, Chidong↗

A Latent Heat Retrieval and its Effects on the Intensity and Structure Change of Hurricane Guillermo (1997). Part I: The Algorithm and Observations.

The release of latent heat in clouds is an essential part of the formation and I intensification o~hurricanes. The community knows very little about the intensity and structure of latent heating due largely to inadequate observations. In this paper, a new method for retrieving the latent heating field in hurricanes from airborne Dopple~ radar is presented and fields from rapidly intensifying Hurricane Guillermo (1997) are shown.

Guimond, Stephen R.↗

Comparative Analysis for EMU Fleet Latent Loading Characterization in Support of US EVA 80 Failure

During United States Extravehicular Activity 80 (US EVA 80), water was observed in the helmet of an Extravehicular Mobility Unit (EMU) during cabin repressurization. One of the primary mechanisms that can cause water in the helmet of an EMU is integrated performance induced sublimator carryover. The sublimator is a heat exchanger that removes heat and humidity from the ventilation loop. Water vapor is condensed from the gas and removed by slurper holes in the sublimator. Sublimator carryover is caused by the inability of the EMU sublimator to remove all of the condensed water vapor, resulting in liquid water entering the helmet. To determine if sublimator carryover was a likely cause of the US EVA 80 failure, a comparative analysis of numerous historical EVAs was conducted to calculate the total latent load (total water vapor generated by the crewmember) for numerous historical EVAs and ground tests using the Systems Improved Numerical Differencing Analyzer EMU (SINDA EMU) model. The analysis showed that US EVA 80 was associated with a comparatively high latent load when compared to other EVAs that did not present water in the helmet. Further, this analysis showed that other historical EVAs which had visible water in the helmet were also associated with higher latent loads. This analysis provides evidence that the likely cause of the US EVA 80 water in the helmet event was not the failure of an individual component, but rather sublimator carryover caused by excessive production of water vapor by the crewmember. The evidence from this analysis agrees with results from the Test, Teardown, and Evaluation (TT&E) of the EMU which did not show any failure of individual components of the EMU that would lead to water in the helmet.

Noah Andersen↗

Corrosion evaluation of metal foams in eutectic molten salts for high temperature latent heat energy storage application

High-temperature Thermal Energy Storage (TES) has drawn great attention as a technology that can increase the role and profitability of micro nuclear reactors in the decentralized clean energy market. Various research needs have been proposed by Idaho National Laboratory (INL) in "the Integrated Energy Systems: 2020 Roadmap" with the goal of utilizing the high temperature of 550 degrees or more generated in the 4th generation reactor to industrial purposes from the standpoint of integrated energy systems [1]. With the recent development of the 4th generation nuclear power plant, including micro nuclear reactor, there is a great deal of interest in researching how to efficiently couple a heat source to an industrial process through thermal processing. Texas A&M University (TAMU) and INL are currently collaborating to develop a novel latent heat storage design called HITB (Heat pipe-Integrated Thermal Battery). As part of the small-scale experimental demonstration research for HITB, a study for storage medium selection was conducted at TAMU. Eutectic salts have attracted interest as high-temperature heat storage medium for HITB. Especially, chloride molten salts and fluoride molten salts are considered promising candidates due to their high melting temperature, thermal stability, and high latent heat of fusion. Since eutectic salts have poor thermal conductivity in general, it is critical to distribute materials with high thermal conductivity evenly to facilitate the charging and discharging of heat. In this study, metal foam was considered in the HITB system to overcome the poor heat transfer characteristics of eutectic salts. In order to improve heat transfer, it is necessary to study materials with high thermal conductivity, corrosion resistant to molten salts, such as fins, extended surfaces, particles, microcapsulation, or foam structure. Porous structure of copper or aluminum can increase heat transfer area, form a thermal transfer network, and increase the effective thermal conductivity of thermal storage medium [2]. Since the melting temperature is required to be at least 450? in the current HITB design, various eutectic salts are being considered. FLiNaK and FLiBe, which are famous for fluoride salts, are good candidates, but due to the sharp rise in the price of LiF recently, they are excluded for economic reasons to be applied to large-capacity thermal energy storage. On the other hand, chloride salts are very cheap and easy to obtain, have a high melting temperature, and have a high latent heat of fusion, so they are recently in the spotlight as a phase change material. However, because of the hygroscopic nature of chloride salts, HCl gas due to impurity is easy to be released and is particularly vulnerable to corrosion. Chloride eutectic salts have been tested and suggested for metal alloys that are particularly resistant to corrosion, such as SS304, SS316, Hastelloy, Inconel 625, Incoloy 800H, which has low thermal conductivity, and is very expensive [3-6]. Porous materials with high thermal conductivity such as copper and aluminum have been tested for stability in fluids such as paraffin or water as metal foam or metal fin structures, but high temperature corrosion tests were not performed on various eutectic salts yet. Therefore, this study investigated the high temperature corrosion characteristics of metal alloys, such as C10100 foam, C10100 plate, 6101 alloy foam, and SS316 plate, while immersed in the candidate eutectic salts. A total of 20 tests for SS316 coupons and 10 tests for C10100 coupons were performed to ensure the repeatability of the present measurements. Since it is difficult to completely remove the salt inside metal foam due to the complex inner structure of the metal foam, only the surface condition was observed with a microscopy and scanning electron microscopy (SEM) image, except for measuring the corrosion rate and average mass loss.

25 ENERGY STORAGE↗

Evaluation of Formate Salt PCM’s for Latent Heat Thermal Energy Storage

This work examines formate salts as potential phase change materials (PCMs) for middle-high temperature (≤250 °C) latent heat thermal energy storage applications. The thermophysical properties of three formate salts were characterized: pure sodium formate and binary blends of sodium/potassium formate and sodium/calcium formate. The stability of formate PCM’s was evaluated by thermal cycling using differential scanning calorimetry where sodium formate and sodium/potassium formate appeared stable over 600 cycles, while sodium/calcium formate exhibited a monotonic decrease in heat of fusion over the test period. A longer test with sodium formate led to gas release and decomposition of the salt. FTIR analysis of the PCM showed degradation of formate to oxalate. T-history experiments with 50-g PCM quantities demonstrated a bulk supercooling of only 2–3 °C for these salts. Thermal conductivity enhancement of over 700% was achieved by embedding aluminum in the solid PCM. Finally, mild carbon steel was immersed in molten sodium formate for up to 2000 h. Sodium formate was found to be non-corrosive, as calculated by mass loss and confirmed by cross-sectional high-resolution microscopy. FTIR analysis of the PCM after 2000 h shows oxidation at the free surface, while the bulk PCM remained unchanged, further indicating a need to protect the formate from atmospheric exposure when used as a PCM.phase change materials; formate salts; latent heat thermal energy storage; thermal cycling; supercooling; thermal conductivity enhancement; corrosion

25 ENERGY STORAGE↗

Latent Mechanisms of Polarization Switching from In Situ Electron Microscopy Observations

In situ scanning transmission electron microscopy enables observation of the domain dynamics in ferroelectric materials as a function of externally applied bias and temperature. The resultant data sets contain a wealth of information on polarization switching and phase transition mechanisms. However, identification of these mechanisms from observational data sets has remained a problem due to a large variety of possible configurations, many of which are degenerate. Here, an approach based on a combination of deep learning-based semantic segmentation, rotationally invariant variational autoencoder (VAE), and non-negative matrix factorization to enable learning of a latent space representation of the data with multiple real-space rotationally equivalent variants mapped to the same latent space descriptors is introduced. By varying the size of training sub-images in the VAE, the degree of complexity in the structural descriptors is tuned from simple domain wall detection to the identification of switching pathways. Importantly, this yields a powerful tool for the exploration of the dynamic data in mesoscopic electron, scanning probe, optical, and chemical imaging. Moreover, this work adds to the growing body of knowledge of incorporating physical constraints into the machine and deep-learning methods to improve learned descriptors of physical phenomena.

36 MATERIALS SCIENCE↗

Dynamic modeling of heat pipe integrated thermal battery latent heat storage system experiment validation

A heat pipe integrated thermal battery system has been constructed to investigate a high-temperature latent heat thermal energy storage technology that takes advantage of near isothermal operation of latent heat storage and heat pipes to potentially enable high-energy isothermal heat storage. A dynamic model constructed in Modelica has been validated, showing errors between 2.5 °C–39.7 °C across 10-h to 47-h simulations against experiment results, showing good prediction capability of experiment output, especially against phase change time. Model calibrations showing vessel heat-up capability of 3 kW and heat pipes combining to provide 600 W each during experiment operation validate experiment circumstances including reduced material loading and reduced power capability. The experiment configuration uses an Al-Mg-Zn eutectic metal as the storage material, heated via heat tape wrapped around the vessel and guide tubes to bring the system to operation range (>400 °C) and to simulate charging heat exchange, respectively, with heat rejection occurring through the surfaces of the material and facilitated via guide tubes with less insulation wrapping. The model is available in the open-source repository HYBRID on Github.

25 - ENERGY STORAGE↗

A fast reduced model for a shell-and-tube based latent heat thermal energy storage heat exchanger and its application for cost optimal design by nonlinear programming

Numerical simulation of latent heat thermal energy storage (LHTES) systems plays a fundamental role in studying the physical process and guiding the engineering design. Discretization of the PDEs describing the nonlinear solidification/melting process of phase change materials (PCMs) leads to a large-scale complex dynamics system, where the system behavior depends on a set of parameters. In a design setting, repeated model evaluations are required over the set of parameters results in significant computational burden. In this paper, an explicit analytic solution was built for the propagation of the solidification front in a cylindrical coordinate. The analytic solution approach is further employed to develop a low computational reduced model (RM) as a module for a shell-and-tube based LHTES heat exchanger. The levelized Cost of Energy (LCOE) is used as a design metric and the RM model is used to apply system-level constraints in the nonlinear programming formulation that facilitates efficient global optimal design of the PCM properties, flow conditions and tube geometries. The use of LCOE as the design metric prevents over design of the heat transfer rate and also establishes a fair ground for evaluation of different thermal storage technologies and their integrated applications with other systems. Optimal results showed that a higher effectiveness results in a higher LCOE; the velocity of the HTF and the length of the channel are highly correlated with each other; both larger PCM latent energy and conductivity result in lower LCOE.

25 ENERGY STORAGE↗

Analysis of basic airflow configurations for separate sensible and latent cooling systems with indoor air recirculation

Separate sensible and latent cooling (SSLC) is a technology with efficiency and comfort advantages over conventional cooling systems used for space conditioning of buildings. Using multiple cooling processes at different temperatures allows SSLC to save energy by raising the evaporation temperature of the sensible cooling process. In this paper, all possible airflow configurations of SSLC systems are enumerated under the following constraints: exactly two heat exchangers are used, and air is recirculated to the conditioned space (no exhaust or outdoor air treatment). Seven designs are identified, with varying free operating variables, and each is modeled. Analysis reveals that several configurations are equivalent, and there is only one unique basic airflow SSLC configuration: the one with the sensible and latent heat exchangers placed in series. The efficiency of the SSLC system is compared against that of the conventional system. Under standard conditions, an SSLC system can improve the coefficient of performance by 14.8%. In addition to the numerical simulation, the optimal operating condition of the basic air configuration of the SSLC system is derived analytically. The basic SSLC system is shown to offer the highest performance improvement when the outdoor temperature is relatively cool and the space sensible heat ratio is high.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

Toward Decoding the Relationship between Domain Structure and Functionality in Ferroelectrics via Hidden Latent Variables

Polarization switching mechanisms in ferroelectric materials are fundamentally linked to local domain structure and the presence of the structural defects, which both can act as nucleation and pinning centers and create local electrostatic and mechanical depolarization fields affecting wall dynamics. However, the general correlative mechanisms between domain structure and polarization dynamics are only weakly explored, precluding insight into the associated physical mechanisms. In this work, the correlation between local domain structures and switching behavior in ferroelectric materials is explored using convolutional encoder–decoder networks, enabling image to spectral (im2spec) and spectral to image (spec2im) translations via encoding of latent variables. The latter reflect the assumption that the relationship between domain structure and polarization switching is parsimonious, i.e., is based upon a small number of local mechanisms. The analysis of latent variables distributions and their real-space representations provides insight into the predictability of the local switching behavior and hence associated physical mechanisms. We further pose that the regions where these correlative relationships are violated, i.e., predictability of the polarization dynamics from domain structure is reduced, represent the obvious target for detailed studies, e.g., in the context of automated experiments. This approach provides a workflow to establish the presence of correlation between local spectral responses and local structure and can be universally applied to spectral imaging techniques such as piezoresponse force microscopy (PFM), scanning tunneling microscopy (STM) and spectroscopy, and electron energy loss spectroscopy (EELS) in scanning transmission electron microscopy (STEM).

36 MATERIALS SCIENCE↗