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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 109 records · Page 6
All sourcesNASA NTRSDOE OSTI
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System Safety Analysis of Complex NASA Systems with Model-Based Engineering (REV B)

The emergence of model-based engineering is transforming design and analysis methodologies. A recognized benefit of model-based engineering is the existence of a “single source of truth” about the system that becomes the authoritative source of data and information for designers, analysts, and developers. This promotes consistency and efficiency as the design emerges and can be used to further optimize the design. Integrating System Safety Engineers to the “single source of truth” will ensure that the outputs of their assessments and analyses are relevant to the design as it evolves. Use of an integrated system model enables near immediate evaluation of a design change as well as development of operational processes for risk assessment and communication. Such models can enable efficient and timely analysis of system hazards (e.g., hazard fault tree analysis and procedure simulations) and produce complete, accurate, and more consistent products (e.g., hazard reports and safety requirement evaluations). Therefore, an agency-sponsored team at Goddard Space Flight Center (GSFC) recently completed a System Safety Study of modeling and testing capabilities as part of a Model-Based Safety and Mission Assurance Initiative (MBSMAI). Using an existing model developed for reliability analyses, GSFC modeling and system safety experts performed system safety analysis/modeling and produced safety products. The team evaluated model-based feasibility to support System Safety Engineering, developed safety analysis modeling processes, and identified tool capability advancement/development needs. These study results indicate model-based engineering is valid and useable for System Safety Engineering for NASA if adequate modeling processes and environment are established.

NASA↗
DOE OSTI2022

Safety and antiviral activity of triple combination broadly neutralizing monoclonal antibody therapy against HIV-1: a phase 1 clinical trial

HIV-1 therapy with single or dual broadly neutralizing antibodies (bNAbs) has shown viral escape, indicating that at least a triple bNAb therapy may be needed for robust suppression of viremia. We performed a two-part study consisting of a single-center, randomized, double-blind, dose-escalation, placebo-controlled first-in-human trial of the HIV-1 V2-glycan-specific antibody PGDM1400 alone or in combination with the V3-glycan-specific antibody PGT121 in 24 adults without HIV in part 1, as well as a multi-center, open-label trial of the combination of PGDM1400, PGT121 and the CD4-binding-site antibody VRC07-523LS in five viremic adults living with HIV not on antiretroviral therapy (ART) in part 2. The primary endpoints were safety, tolerability and pharmacokinetics for both parts and antiviral activity among viremic adults living with HIV and not on ART for part 2 of the study. The secondary endpoints were changes in CD4 + T cell counts and development of HIV-1 sequence variations associated with PGDM1400, PGT121 and VRC07-523LS resistance in part 2. Intravenously administered PGDM1400 was safe and well-tolerated at doses up to 30 mg kg -1 and when given in combination with PGT121 and VRC07-523LS. A single intravenous infusion of 20 mg kg -1 of each of the three antibodies reduced plasma HIV RNA levels in viremic individuals by a maximum mean of 2.04 log10 copies per ml; however, viral rebound occurred in all participants within a median of 20 days after nadir. Rebound viruses demonstrated partial to complete resistance to PGDM1400 and PGT121 in vitro, whereas susceptibility to VRC07-523LS was preserved. Viral rebound occurred despite mean VRC07-523LS serum concentrations of 93 µg ml -1 . The trial met the pre-specified endpoints. Our data suggest that future bNAb combinations likely need to achieve broad antiviral activity, while also maintaining high serum concentrations, to mediate viral control.

60 APPLIED LIFE SCIENCES↗
DOE OSTI2020

Decommissioning of the V1 Nuclear Power Plant Jaslovske Bohunice - 20270

The paper focuses on introducing the approach and method applied for decommissioning of the V1 nuclear power plant (further the 'V1 NPP') located in Jaslovske Bohunice in the Slovak Republic, to the conference participants. The Paper outlines activities and steps necessary to comply with the requirements contained in the decision of the Slovak government from 1999 regarding the early shutdown of the V1 NPP. The company responsible for the V1 NPP decommissioning is Jadrova a vyradovacia spolocnost, a.s., (further JAVYS) with the State as a sole shareholder. On the basis of the V1 NPP Decommissioning Conceptual Plan, out of four assessed options, JAVYS selected the immediate decommissioning option (the 'IDO') for the V1 NPP. On the basis of multi-criteria analysis, the IDO specified the approach of immediate and continuous dismantling of equipment followed by demolition of buildings and preparation of the site for its further potential use. The IDO also included the summary of technical, environmental, legislative information as well as the determination of assumed costs for decommissioning of the V1 NPP. Prior to commencement of the V1 NPP decommissioning, within the process of termination of operation, activities connected with de-fuelling, monitoring, processing of historical waste and, not to forget, the process of obtaining the license for the V1 NPP decommissioning were executed. JAVYS decided to divide the decommissioning process into two stages. In 2011, JAVYS obtained a license for the first stage of the V1 NPP decommissioning. Within this stage, dismantling of inactive equipment, demolitions of inactive buildings, monitoring of systems and preparatory works for the upcoming stage of decommissioning were implemented. In 2015, in line with the license for the 2. stage of the V1 NPP decommissioning, the activities of decontamination and dismantling of contaminated and active equipment as well as demolitions of remaining buildings began. In this stage radioactive waste (RAW) produced during the decommissioning is to be processed. After decontamination, the material fulfilling the free release criteria is to be released into the environment, the site is to be cleared from the scope of the Atomic Act and released from the surveillance of the national regulators. Future application of certain methods and techniques for decontamination and dismantling in similar environments might bring an added value to the operators. Paper includes a description of best practices for Nuclear Power Plant VVER type reactors decommissioning. Schedule comparison is given to show how the critical path of certain projects is being managed. Application of the International Standard for Decommissioning Costing (ISDC) methodology provides a uniform method which enables comparison of cost estimates to other nuclear facilities under decommissioning. The cost estimate for the V1 NPP decommissioning has been continuously updated based on more advanced and detailed information on the decommissioning activities and projects. Monitoring of progress of the V1 NPP decommissioning is performed via four key-performance indicators. The Earned Value Management (EVM) methodology is used for evaluating time and cost aspect of decommissioning activities while waste conditioning index is calculated by comparing the actually produced waste to planned values of waste for a respective monitored period. Radiological safety index is assessed by comparison of the personnel records on the individual yearly doses received by each respective employee to the boundary value. (authors)

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗
DOE OSTI2025

Failure Analysis–Informed Risk Assessment Framework for Geological Carbon Storage Using Numerical Simulation and Machine Learning

Geological carbon storage (GCS) is recognized as a critical technology for achieving large-scale reductions in anthropogenic carbon dioxide (CO 2 ) emissions. Ensuring long-term containment and safety requires robust risk assessment frameworks that account for geological uncertainty and identify potential failure scenarios. Among various indicators, the area of review (AoR) serves as a key metric for evaluating storage performance, regulatory compliance, and monitoring design, as it delineates the spatial extent impacted by pressure buildup and plume migration. However, conventional AoR-based risk assessments typically perturb parameters within narrow uncertainty bounds, potentially overlooking rare but high-impact events arising from extreme geological conditions. In this study, we present a failure analysis–informed risk assessment framework for large-scale GCS projects to improve site prescreening and monitoring design. A suite of 300 numerical simulations was generated using stochastic geological models that vary five key parameters: net-to-gross ratio, anisotropy azimuth, porosity multiplier, permeability multiplier, and vertical-to-horizontal permeability ratio. Among these, 200 realizations represent normal geological uncertainty, while 100 additional cases explore extreme yet plausible conditions for failure-case analysis. The AoR was simulated and computed from pressure and CO 2 saturation fields, where the baseline AoR boundary, representing the extent predicted under typical geological uncertainty, was defined as the union of 200 normal-range simulations, and failure was identified when extreme-range cases exceeded this baseline. Results show that incorporating broader parameter uncertainty produces significantly larger AoR extents, underscoring the potential underestimation of risk under conventional uncertainty ranges. Furthermore, spatial probability maps derived from failure-induced AoR exceedance identify regions requiring enhanced monitoring attention. Various machine learning (ML)–based classifiers were developed to predict failure occurrence from geological parameters, with the random forest model achieving the highest performance (F1-score of 0.986). Consistent findings from correlation coefficient, feature importance, and Sobol sensitivity analyses reveal that low net-to-gross ratios and permeability multipliers are the dominant risk drivers, reflecting reduced reservoir connectivity and limited pressure dissipation. Altogether, these results provide a novel framework for risk-informed site prescreening and monitoring design that explicitly considers rare but high-impact geological scenarios in GCS projects.

25 ENERGY STORAGE↗
NASA NTRS1975

Evaluation of class 2 biological cabinets

Basic investigations, consisting primarily of airflow measurements and visual smoke tests, were made on four commercially available units. The results indicated that performance varied considerably between units. Therefore, it was decided to outline the performance desired and to include in the overall equipment specifications a set of performance tests to assure a clean air safety cabinet with respect to chemical usage. The evaluation was to be based on aerodynamic performance under the various modes of operation.

Chamberlin, R. E.↗
NASA NTRS1991

Autonomous guidance, navigation and control bridging program plan

A four-center NASA team has undertaken to develop and demonstrate mature technologies applicable to autonomous guidance, navigation, and control (GNC) systems for application to the National Space Transportation System in full cognizance of its operational, safety, and performance requirements, as well as its cost constraints. Attention is to be given to GNC launch/landing weather assessment, ascent guidance, ascent load relief, and system failure during ascent. Preliminary results indicate that a ground-computed atmospheric steering profile can achieve near-optimum performance as well as high cost effectiveness.

Mcswain, G. G.↗
NASA NTRS1976

Guidelines for advanced manned space vehicle program, June 1960

A very broad mission objective was established; i.e., manned circumlunar flight and return to earth. It is implicit that the Saturn will be the primary propulsion system for this mission. The following attempts to: (1) define the objective so as to achieve as much capability in the vehicle as possible; (2) draw on Mercury experience to provide broad guidelines for vehicle performance and safety; (3) provide flexibility in the vehicle capability in the event that the manned lunar mission is proved to be subject to unacceptable risk in the target time period; and (4) indicate problem areas where work appears to be particularly needed.

Gilruth, R. R.↗
DOE OSTI2021

DESIGN AND PROTOYPING OF A FISSILE-BEARING CHLORIDE SALT IRRADIATION EXPERIMENT

Limited data exists on the properties of irradiated fueled chloride-based salts for use in advanced nuclear reactors. The design and prototyping of a salt irradiation experiment is underway. Mechanical design will integrate the experiment into existing assemblies in TRIGA type cores. Neutronics modeling demonstrated how targeted power densities can be reached and provide insight on radionuclide source term generation within the experiment. Thermal-hydraulic and computational fluid dynamics (CFD) analysis indicated that temperature ranges in the salt can satisfy both safety and programmatic requirements. Initial prototyping tests provided confidence in the ability to extract the salt post-irradiation, and in the heater performance. Future planned prototyping will provide an integral assessment of the proposed design prior to insertion in the reactor.

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗
NASA NTRS2016

Task Demand Variation in Air Traffic Control: Implications for Workload, Fatigue, and Performance

In air traffic control, task demand and workload have important implications for the safety and efficiency of air traffic, and remain dominant considerations. Within air traffic control, task demand is dynamic. However, research on demand transitions and subsequent controller perception and performance is limited. This research uses an air traffic control simulation to investigate the effect of task demand transitions, and the direction of those transitions, on workload and fatigue and one efficiency performance measure. Results indicate that a change in task demand appears to affect both workload and fatigue ratings, although not necessarily performance. In addition, participants' workload and fatigue ratings in equivalent task demand periods appear to change depending on the demand period preceding the time of the current ratings. Further research is needed to enhance understanding of demand transition and workload history effects on operator experience and performance, in both air traffic control and other safety-critical domains.

workload history↗
NASA NTRS2016

Task Demand Variation in Air Traffic Control: Implications for Controller Workload, Fatigue, and Performance

In air traffic control, task demand and workload have important implications for the safety and efficiency of air traffic, and remain dominant considerations. Within air traffic control, task demand is dynamic. However, research on demand transitions and subsequent controller perception and performance is limited. This research uses an air traffic control simulation to investigate the effect of task demand transitions, and the direction of those transitions, on workload and fatigue and one efficiency performance measure. Results indicate that a change in task demand appears to affect both workload and fatigue ratings, although not necessarily performance. In addition, participants workload and fatigue ratings in equivalent task demand periods appear to change depending on the demand period preceding the time of the current ratings. Further research is needed to enhance understanding of demand transition and workload history effects on operator experience and performance, in both air traffic control and other safety-critical domains.

workload history↗
DOE OSTI2025

Diffusion Behavior of Oversized Fission Products in bcc Fe Cladding: A First-Principles Study

Fuel-Cladding Chemical Interaction (FCCI) poses significant challenges in nuclear reactors, where fission products from nuclear fuel interact with Fe-based cladding materials, potentially compromising their structural integrity. This study investigates the diffusion behavior of oversized fission products, Pr, Nd, Ce, and La, within bcc Fe cladding using density functional theory (DFT), nudged elastic band (NEB) method, and self-consistent mean field (SCMF) theory. Our results reveal significant long-range vacancy binding energies, particularly up to the 6th nearest neighbor, with La exhibiting the strongest binding affinity, followed by Nd, Ce, and Pr. The NEB calculations indicate significant high barriers for the dissociation of 1nn vacancy-solute pairs for all fission products. The tracer diffusion coefficients of these fission products was derived in Arrhenius form. The significant trapping effect of vacancies by a very dilute amount of fission products reduces vacancy mobility, leading to an oversaturation of point defects, void nucleation, and swelling. These are critical issues for irradiated cladding materials. The tracer diffusion coefficients indicate that Nd diffuses the fastest, followed by La, Ce, and Pr. This study provides essential insights for developing advanced cladding materials and design strategies to mitigate FCCI, ultimately enhancing nuclear reactor safety and performance.

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗
NASA NTRS2014

Space Mission Human Reliability Analysis (HRA) Project

The purpose of the Space Mission Human Reliability Analysis (HRA) Project is to extend current ground-based HRA risk prediction techniques to a long-duration, space-based tool. Ground-based HRA methodology has been shown to be a reasonable tool for short-duration space missions, such as Space Shuttle and lunar fly-bys. However, longer-duration deep-space missions, such as asteroid and Mars missions, will require the crew to be in space for as long as 400 to 900 day missions with periods of extended autonomy and self-sufficiency. Current indications show higher risk due to fatigue, physiological effects due to extended low gravity environments, and others, may impact HRA predictions. For this project, Safety & Mission Assurance (S&MA) will work with Human Health & Performance (HH&P) to establish what is currently used to assess human reliabiilty for human space programs, identify human performance factors that may be sensitive to long duration space flight, collect available historical data, and update current tools to account for performance shaping factors believed to be important to such missions. This effort will also contribute data to the Human Performance Data Repository and influence the Space Human Factors Engineering research risks and gaps (part of the HRP Program). An accurate risk predictor mitigates Loss of Crew (LOC) and Loss of Mission (LOM).The end result will be an updated HRA model that can effectively predict risk on long-duration missions.

Boyer, Roger↗
NASA NTRS1986

Oxygen/hydrogen Space Station propulsion system concept definition for IOC

The potential for the reduction in propulsion system life cycle costs through the use of on-board water electrolysis to generate oxygen and hydrogen propellants, as well as the potential advantages of improved system safety and contamination impact, led to a study to evaluate candidate oxygen-/hydrogen-based propulsion systems. In this study a representative set of propulsion system requirements were compiled and candidate oxygen/hydrogen-based propulsion systems synthesized. These candidate concepts were screened and a systems evaluation was performed on the remaining eight candidate concepts. Detailed system schematics were prepared. Operational design conditions were determined and system weight, volume, energy requirements, and costs were calculated. Evaluation results indicated that the oxygen/hydrogen propulsion systems can provide simple, low cost, and viable systems for the IOC Space Station. Based on these data, a relative concept evaluation was conducted using as selection criteria reliability, safety, cost, technical risk, contamination, operational utility, growth potential, and integration potential. Top ranked candidate systems were recommended to NASA/MSFC for consideration for the IOC Space Station.

Shoji, J. M.↗
DOE OSTI2023

Energetic particle marginal stability profile for HL-2M integrated simulation based on neural network module

Abstract A critical gradient model is employed to develop a module of energetic particle (EP) marginal stability profiles in OMFIT integrated simulations for studying EP transport. Currently, each iteration of transport evolution is approximately 10 min in the integrated simulation, whereas, the EP marginal stability profile, which serves as an input in the integrated simulation could take much longer; the reason being a combination of the TGLFEP and EPtran codes is employed in our previous investigation. To reduce the simulation time, the critical gradient is predicted by a neural network instead of the TGLFEP code, and the EPtran code is revised with parallel computing, so that the running time of this module can be controlled to within 5 min. The predictions are in good agreement with previous approaches. The integrated simulation of HL-2M with Alfven eigenmodes transported by neutral beam EP profiles indicates that EP transport reduces the total pressure and current as expected, but could also under some conditions raise the safety factor in the core, which is favorable for reversed magnetic shear and high-performance plasmas.

Physics↗
NASA NTRS2005

The Small Aircraft Transportation System Higher Volume Operations (SATS HVO) Flight Experiment

This paper provides a summary of conclusions from the Small Aircraft Transportation System (SATS) Higher Volume Operations (HVO) Flight Experiment which NASA conducted to determine pilot acceptability of the HVO concept for normal conditions. The SATS HVO concept improves efficiency at non-towered, non-radar airports in Instrument Meteorological Conditions (IMC) while achieving a level of safety equal to today s system. Reported are results from flight experiment data that indicate that the SATS HVO concept is viable. The success of the SATS HVO concept is based on acceptable pilot workload, performance, and subjective criteria when compared to the procedural control operations in use today at non-towered, non-radar controlled airfields in IMC. The HVO Flight Experiment, flown on NASA's Cirrus SR22, used a subset of the HVO Simulation Experiment scenarios and evaluation pilots in order to validate the simulation experiment results. HVO and Baseline (today s system) scenarios flown included: single aircraft arriving for a GPS non-precision approach; aircraft arriving for the approach with multiple traffic aircraft; and aircraft arriving for the approach with multiple traffic aircraft and then conducting a missed approach. Results reveal that all twelve low-time instrument-rated pilots preferred SATS HVO when compared to current procedural separation operations. These pilots also flew the HVO procedures safely and proficiently without additional workload in comparison to today s system (Baseline). Detailed results of pilot flight technical error, and their subjective assessments of workload and situation awareness are presented in this paper.

Williams, Daniel M.↗
NASA NTRS1975

The Airfloat HL project

A design study is described for a large low-cost rigid airship intended primarily for the movement of large indivisible loads (cargo) between industrial sites. A survey of the ship and its overall performance is followed by accounts of the operational procedures for the above function and for an alternative application to unit module transfer between fixed terminals. A final section indicates the estimated costs of construction and operation. Safety factors are also considered. Lifting devices such as winches, hoists are shown and described, and airship configurations are also shown.

Mowforth, E.↗
NASA NTRS1975

Astronaut activity

Human factors pertinent to the design and operation of spacecraft are considered. The geometric characteristics of spacecraft that define the degree and type of confinement imposed on the crew and the character of equipment management and housekeeping necessary for hygiene, comfort and safety are discussed. The controls and displays of various spacecraft are described to indicate the degree to which crew functions become integral to functions of the total spacecraft. The contributions of the crew to system reliability and performance are summarized and the increasing significance of the crew's role in scientific observation and experimentation is noted.

Loftus, J. P., Jr.↗
NASA NTRS2023

Software Error Incident Categorizations in Aerospace

Since the first use of computers in space and aircraft, software errors have occurred. These errors can manifest as loss-of-life or less catastrophically. As the demand for automation increases, software in safety-critical systems should be designed to be tolerant to the most likely software faults. This paper categorizes historic aerospace software errors to determine trends of how and where automation is most likely to fail. A distinction between software producing wrong (erroneous) output versus no output (fail-silent) is introduced. Of the historical incidents analyzed, 87% were from software acting unexpectedly rather than simply stopping. Rebooting was found to be ineffective to clear erroneous behavior, and only partially effective for silent software. Errors were traced back to the software logic itself in 62% of cases, 13% within configurable data, and 25% introduced through input. Thirty percent (30%) of unexpected software behavior was caused by the absence of software and 20% was due to “unknown-unknowns”. These findings indicate that to achieve fault tolerance in safety-critical systems, backup strategies must be employed to detect and respond to erroneous software behavior beyond only fail-silent cases, and robust off-nominal testing should be performed to uncover unanticipated situations.

Software↗