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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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All sourcesNASA NTRSDOE OSTI
DOE OSTI2021

International Collaborations Activities on Disposal in Argillite R&D: Characterization Studies and Modeling Investigations

This interim report is an update of ongoing experimental and modeling work on bentonite material described in Jové Colón et al. (2019, 2020) from past international collaboration activities. As noted in Jové Colón et al. (2020), work on international repository science activities such as FEBEX-DP and DECOVALEX19 is either no longer continuing by the international partners. Nevertheless, research activities on the collected sample materials and field data are still ongoing. Descriptions of these underground research laboratory (URL) R&D activities are described elsewhere (Birkholzer et al. 2019; Jové Colón et al. 2020) but will be explained here when needed. The current reports recent reactive-transport modeling on the leaching of sedimentary rock.

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗
NASA NTRS2014

Maiden Voyage of the Rodent Habitat on ISS: Opportunities for Investigating Molecular Mechanisms and Biomedical Consequences of Long Duration Spaceflight

Research using rodents is an essential tool for advancing biomedical research on Earth and in space. The National Research Counsel’s Decadal survey (1) emphasized the importance of expanding NASAs life sciences research to perform long duration, rodent experiments on the International Space Station (ISS). To accomplish this objective, flight hardware, operations, and science capabilities were developed at NASA ARC to support both commercial and government-sponsored research. In preparation for the maiden voyage of the Rodent Habitat hardware and operations system (Rodent Research-1), and in close consultation with a Science Working Group comprised of veterinarians and experienced spaceflight investigators, we modified existing Animal Enclosure Module hardware, developed new hardware, operations, and science activities, and performed a series of ground-based verification tests. Preflight, ground based hardware tests included a simulation of SpaceX Dragon launch conditions (vibration and hypergravity) using the Transporter, and also two long-term biocompatibility tests (32 and 92 days) using the Habitat developed for long term housing on the ISS. The launch simulation test showed that adult mice housed in Transporter hardware adapted well, even if launch simulation was followed by a period of simulated weightlessness (via hind limb unloading). The biocompatibility tests demonstrated that the Habitat successfully supported animal health and also provided a useful video imaging system that enables frequent monitoring of animal health and behavior by veterinary and scientific experts on the ground, independent of ISS crew intervention. At the conclusion of all tests, mice were deemed healthy and suitable for conducting biological research. Additional preflight analyses of tissues preserved by freezing or fixation for gene expression analyses revealed that spleen and liver tissues recovered under conditions that simulated on-orbit activities yielded high quality RNA (RIN values 8-10) and liver enzyme activities and protein content (e.g. catalase). In addition, new methods were developed to optimize future science return by dissecting tissues post-euthanasia and storage. Various tissues were harvested from either intact or partially dissected, frozen carcasses after storage for ~2-6 months; most of the tissues (brain, heart, kidney, eye, adrenal glands and skeletal muscle) were of high RNA quality for science return, whereas some tissues (small intestine, bone marrow and bones) were not. These data demonstrated the protocols developed for future flight experiments supported science return despite delayed preservation post-euthanasia or prolonged storage, and furthermore, that high-quality RNA samples from many different tissues can be recovered by dissection following prolonged storage of the tissue in situ at -80˚C. The first flight experiments carrying 20 mice were launched on Sept 21, 2014 in an unmanned Dragon Capsule, SpaceX4; Rodent Research-1 is dedicated to achieving both NASA validation and CASIS science objectives. Ground based control groups (housed in flight hardware or standard cages) were maintained in environmental chambers at Kennedy Space Center. Crewmembers previously trained in animal handling transferred mice from the Transporter into Habitats under simultaneous veterinary supervision by video streaming and were deemed healthy. Health and behavior of all mice on the ISS was monitored by video feed on a daily basis. The 10 mice for validation (16wk old, female C57Bl6/J) ambulated freely and actively throughout the Habitat, relying heavily on their forelimbs for locomotion. The first on-orbit dissections of mice were performed successfully on Oct 12 and 13, 2014, and the validation mice will reside on ISS for up to 30 days. In conclusion, new capability for long duration rodent research is under development, including in-flight sample collection (which avoids the complication of reentry); results obtained to date will be described. This new Rodent Research system enables achievement of both basic science and translational research objectives to advance human exploration of space.

maiden voyage↗
DOE OSTI2017

Geographic Information Systems as an Opportunity for Public Engagement in Environmental Data Analysis for Nuclear Waste Management - 17505

For half a century, scientists across government agencies, industry, academia and other research organizations have been using geographic information system (GIS) tools to display data collected for a wide variety of programs. Recent technology advances have made it possible for the public to also use GIS tools to display data. Meanwhile, around the world, volunteers are increasingly participating in citizen science activities that involve collecting environmental observations and measurements. Considering themes of broad interest to which citizen science and GIS tools could be applied, integrated nuclear waste management represents a potential opportunity for public engagement in environmental data analysis. In the United States, the Department of Energy's (DOE's) goal is to develop solutions for the long-term, sustainable management of the nation's spent nuclear fuel (SNF) and high-level radioactive waste (HLW) from commercial electricity generation, as well as national defense activities. The DOE has been exploring options for an integrated waste management system to transport, store, and dispose of SNF and HLW. To support its efforts, DOE has been exploring ways to seek broad input from the public. Literature was reviewed to assess recent advances in GIS technology and citizen science that could contribute to public engagement in waste management planning. Results identified a variety of promising tools and applications that are readily accessible online, including QGIS and the U.S. Environmental Protection Agency's (EPA's) Real Time Geo-spatial Data Viewer (RETIGO). For example, interested members of the public could illustrate air quality, water quality, and other environmental data in GIS plots to visually represent local conditions over time. This paper highlights potential opportunities for those interested in citizen science and GIS tools as part of exploring options for public engagement in planning for an integrated waste management system. (authors)

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗
NASA NTRS2014

Ground Data System Analysis Tools to Track Flight System State Parameters for the Mars Science Laboratory (MSL) and Beyond

Flight software parameters enable space mission operators fine-tuned control over flight system configurations, enabling rapid and dynamic changes to ongoing science activities in a much more flexible manner than can be accomplished with (otherwise broadly used) configuration file based approaches. The Mars Science Laboratory (MSL), Curiosity, makes extensive use of parameters to support complex, daily activities via commanded changes to said parameters in memory. However, as the loss of Mars Global Surveyor (MGS) in 2006 demonstrated, flight system management by parameters brings with it risks, including the possibility of losing track of the flight system configuration and the threat of invalid command executions. To mitigate this risk a growing number of missions have funded efforts to implement parameter tracking parameter state software tools and services including MSL and the Soil Moisture Active Passive (SMAP) mission. This paper will discuss the engineering challenges and resulting software architecture of MSL's onboard parameter state tracking software and discuss the road forward to make parameter management tools suitable for use on multiple missions.

Allard, Dan↗
NASA NTRS2005

The Different Wavelengths of Radio Science

Radio Science covers many different avenues. This summer I attempted to work in each of the different avenues to learn the full range of subjects covered by Radio Science. I began my summer by traveling to Greece for the 3rd International Planetary Probe Workshop (IPPW-3). I went as a co-author of the Doppler Wind Experiment (DWE) team paper. My first job when I returned from Greece was to update the Radio Science activities webpage. I then used Fast Fourier Transforms (FFT) to find radio signals in recorded Radio Science experimental data and determine frequencies and powers. I read about and ran Fortran code being used to determine wind measurements on Huygens. I formatted and revised the abstracts and data lengths for the DVD data sets. By performing these tasks, I also learned the Unix operating system as well as a small amount of shell programming.

Malecha, Jessica L.↗
DOE OSTI2022

2021 Annual Report: Atmospheric Radiation Measurement

In fiscal year 2021 (FY2021), the COVID-19 pandemic continued to have an impact on activities within the Atmospheric Radiation Measurement (ARM) user facility. Travel was limited, which affected field activities and forced the continuation of virtual meetings. However, the ability to travel expanded significantly through the year, bringing some return to normalcy, and throughout the year, there was a great deal of activity dedicated to advancing the facility. Because of COVID, ARM twice delayed the TRacking Aerosol Convection interactions ExpeRiment (TRACER) in the Houston, Texas, area. Originally planned to launch in the spring, TRACER started October 1, 2021, one month after the Surface Atmosphere Integrated Field Laboratory (SAIL) campaign began near Crested Butte, Colorado. ARM teams worked onsite and remotely to make sure both campaigns could launch on this new schedule that was set early in the year. Data from SAIL and TRACER will be critical to improving earth system models, each contributing to different sets of issues. SAIL measurements will provide insights into how precipitation forms and water travels through the Upper Colorado River Basin. TRACER scientists want to know whether tiny atmospheric particles can influence the severity of thunderstorms. In October 2020, the Multidisciplinary Drifting Observatory for the Study of Arctic Climate (MOSAiC) expedition ended after 13 months. MOSAiC data from ARM and other organizations are already helping scientists better understand how ice, atmosphere, and ocean systems are connected in the central Arctic. This report discusses some early investigations from MOSAiC, along with other ARM campaigns and activities generating prolific research. In this report, you will also learn how research activities moved forward during the pandemic at ARM’s fixed-location atmospheric observatories. There were important science applications from measurements across the facility. ARM spent a significant amount of FY2021 looking back—and ahead. In November 2020, ARM had its Triennial Review. This review is held every three years to evaluate ARM’s effectiveness in science, operations, and management. Overall, the reviewers had positive feedback regarding the breadth and impact of science activities using ARM data and the way ARM strives to meet changing user needs. The reviewers also provided some recommendations for strengthening ARM going forward. Incorporating feedback from the review, we finalized an updated Decadal Vision document that will help guide ARM priorities in the coming years. This report describes the four themes driving ARM’s Decadal Vision.

54 ENVIRONMENTAL SCIENCES↗
DOE OSTI2023

DSI Python API Demo May 2023 [Slides]

Data Science Infrastructure (DSI) is developing searchable databases and workflows for simulation and experimental data derived from ASC clients. Short term goal: Make data easily accessible through metadata indexing and querying while respecting data permissions. Longer term goal: Use this data for data science activities.

97 MATHEMATICS AND COMPUTING↗
NASA NTRS2012

HURON (HUman and Robotic Optimization Network) Multi-Agent Temporal Activity Planner/Scheduler

HURON solves the problem of how to optimize a plan and schedule for assigning multiple agents to a temporal sequence of actions (e.g., science tasks). Developed as a generic planning and scheduling tool, HURON has been used to optimize space mission surface operations. The tool has also been used to analyze lunar architectures for a variety of surface operational scenarios in order to maximize return on investment and productivity. These scenarios include numerous science activities performed by a diverse set of agents: humans, teleoperated rovers, and autonomous rovers. Once given a set of agents, activities, resources, resource constraints, temporal constraints, and de pendencies, HURON computes an optimal schedule that meets a specified goal (e.g., maximum productivity or minimum time), subject to the constraints. HURON performs planning and scheduling optimization as a graph search in state-space with forward progression. Each node in the graph contains a state instance. Starting with the initial node, a graph is automatically constructed with new successive nodes of each new state to explore. The optimization uses a set of pre-conditions and post-conditions to create the children states. The Python language was adopted to not only enable more agile development, but to also allow the domain experts to easily define their optimization models. A graphical user interface was also developed to facilitate real-time search information feedback and interaction by the operator in the search optimization process. The HURON package has many potential uses in the fields of Operations Research and Management Science where this technology applies to many commercial domains requiring optimization to reduce costs. For example, optimizing a fleet of transportation truck routes, aircraft flight scheduling, and other route-planning scenarios involving multiple agent task optimization would all benefit by using HURON.

Hua, Hook↗
DOE OSTI2020

International Collaborations Activities on Disposal in Argillite R&D: Bentonite Barrier Characterization Studies and Modeling Investigations

This interim report is an update of the report Jove Colon et al. (2019; M4SF-19SN010301091) describing international collaboration activities pertaining to FEBEX-DP and DECOVALEX19 Task C projects. Although work on these two international repository science activities is no longer continuing by the international partners, investigations on the collected data and samples is still ongoing. Descriptions of these underground research laboratory (URL) R&D activities are given in Jové Colón et al. (2018; 2019) but will repeated here for completeness. The 2019 status of work conducted at Sandia National Laboratories (SNL) on these two activities is summarized along with other international collaboration activities in Birkholzer et al. (2019).

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗
NASA NTRS2011

Attitude Determination and Control Subsystem (ADCS) Preparations for the EPOXI Flyby of Comet Hartley 2

On November 4, 2010 the former "Deep Impact" spacecraft, renamed "EPOXI" for its extended mission, flew within 700km of comet 103P/Hartley 2. In July 2005, the spacecraft had previously imaged a probe impact of comet Tempel 1. The EPOXI flyby was the fifth close encounter of a spacecraft with a comet nucleus and marked the first time in history that two comet nuclei were imaged at close range with the same suite of onboard science instruments. This challenging objective made the function of the attitude determination and control subsystem (ADCS) critical to the successful execution of the EPOXI flyby.As part of the spacecraft flyby preparations, the ADCS operations team had to perform meticulous sequence reviews, implement complex spacecraft engineering and science activities and perform numerous onboard calibrations. ADCS contributions included design and execution of 10 trajectory correction maneuvers, the science calibration of the two telescopic instruments, an in-flight demonstration of high-rate turns between Earth and comet point, and an ongoing assessment of reaction wheel health. The ADCS team was also responsible for command sequences that included updates to the onboard ephemeris and sun sensor coefficients and implementation of reaction wheel assembly (RWA) de-saturations.

attitude determination and control↗
NASA NTRS1991

Agreements/subagreements Applicable to Wallops, 12 Nov. 1991

The status of space science agreements are noted. A general overview of the Wallops Flight Facility (WFF) is given. The geography, history, and mission of the facility are briefly surveyed. Brief accounts are given of NASA earth science activities at the WFF, including atmospheric dynamics, atmospheric optics, ocean physics, microwave altimetry, ocean color research, wind-wave-current interaction, flight support activities, the Sounding Rocket Program, and the NASA Balloon Program. Also discussed are the WFF launch range, the research airport, aircraft airborne science, telemetry, data systems, communications, and command and control.

Source record↗
DOE OSTI2022

U.S. Pacific Coast Workshop Report on Preconstruction Research Recommendations (U.S. Offshore Wind Synthesis of Environmental Effects Research (SEER) Project)

In May 2022, the U.S. Offshore Wind Synthesis of Environmental Effects Research (SEER) project team hosted a stakeholder workshop focused on preconstruction (baseline) research needs for potential floating offshore wind (OSW) energy development on the U.S. Pacific Coast, including California, Oregon, and Washington. Prior to the workshop, the SEER team developed a set of initial synthesized research recommendations that were identified based on a review of relevant, publicly available resources and with advisory group input. The workshop covered three marine life breakout groups on subsequent days to discuss research recommendations related to 1) marine mammals and sea turtles, 2) fish and invertebrates, and 3) birds and bats. As part of the workshop, over a hundred participants from the public and private sectors provided feedback on various aspects of the initial research recommendations, including associated data and knowledge gaps, benefits/limitations of available methods and technologies, and technological advancements or infrastructure needed to address the recommendation. Approximately 1,000 total comments were received on the workshop MURAL boards and were synthesized in this report. Based on workshop feedback, SEER developed a final database of over 500 specific research recommendations based on more than 40 resources. In Fall 2022, the full database and a tool with updated synthesized research recommendations were disseminated on Tethys (https://tethys.pnnl.gov) to assist with informing future funding opportunities and research programming. There is a continued need to improve awareness of the potential environmental effects, monitoring technologies, and management strategies for floating OSW energy development on the U.S. Pacific Coast. Coordination of these activities will require the sustained involvement of multiple stakeholders from across sectors. Beyond the baseline considerations discussed in this workshop, future state-of-the-science activities should be planned to consider research needs across wind energy life cycle phases for all relevant wildlife taxa and associated habitat and ecosystem processes.

17 WIND ENERGY↗
NASA NTRSDate not supplied

Building Sustainable Capacity within Under-Represented Communities Through A Deep Partnership Model

Despite varied programmatic inducements and the documented benefits of Diversity Equity & Inclusion (DE&I), participation rates of underrepresented communities within NASA’s planetary sciences activities have remained low and nearly unchanged over the last decade. The lack of success of various efforts may be attributable to factors identified in social science research. First, the proportionality of under-represented groups has been shown to be critical to achieving the positive impacts of DE&I. When under-represented groups make up less than ~30%, group dynamics such as assimilation or tokenism routinely appear, with destructive and counter-productive results. Additionally, if participation only occurs within limited segments of an organization, benefits may be limited. Proportionality must extend across all levels or layers of the organization for the benefits of DE&I to accrue. Second, the inclusion of “Third Spaces” in the planning and support of DE&I efforts is critical to the long-term success or “stickiness” of DE&I activities. Third Spaces are those beyond home (First Space) and work (Second Space) where informal, community-building activities occur. Examples include conferences, after-work activities, and weekend social engagements. Without explicitly acknowledging and including “Third Space” interactions, DE&I efforts can fall short of their long-term goals. In 2014, the Laboratory for Atmospheric and Space Physics (LASP) at the University of Colorado Boulder began a partnership with the United Arab Emirates to develop and fly a space mission to Mars. The scientific mission had an explicit goal of training scientists and engineers, and creating a sustainable ecosystem that would spark and accelerate the UAE’s space economy. To accomplish this, LASP and the UAE set up a program that matched scientists and engineers in one-on-one mentorship relationships, at all levels of the organization. Over the course of the roughly 4-year project, those partnering relationships fostered not only strong professional relationships and knowledge transfer, but also personal friendships that extended into “Third Spaces.” The UAE/LASP partnership now continues through the co-development of an asteroid mission currently in definition phase. In collaboration with NASA Ames Research Center, LASP is developing the conceptual frame work to extend this deep partnership model to domestic opportunities. By implementing a planetary science mission that employs an analogous one-on-one partnership model across all elements of the organization, this project will demonstrate how proportionality and Third Space relationships can enable the development of localized, sustainable communities that are explicitly and deeply engaged with the NASA ecosystem.

Capacity Building↗
NASA NTRS2006

Jet Propulsion Laboratory: Annual Report 2005

What an amazing host of new sights 2005 brought us. With impeccable choreography, one spacecraft sent an impactor slamming into a comet, reversing the traditional view of these space wayfarers by revealing it to be buried in deep drifts of a fine talcum-like powder. Another spacecraft delivered a probe from our European partners to the surface of Saturn's haze-shrouded moon Titan, disclosing a landscape eerily like Earth's, if we had methane rivers cascading down hillsides of ice. An orbiting observatory for the first time showed us the light from planets circling other stars, which astronomers previously knew to exist only from indirect clues. Throughout the year we also amassed continually expanding views of Earth as well as Mars, by far the most-explored planet after our own. In all, 18 spacecraft and five instruments were stationed across the solar system, studying our own world, other planets, comets and the deeper universe. These missions were enabled by the efforts of everyone at JPL. The Deep Space Network of communications complexes across three continents continued to experience a period of remarkable activity. Others were at work creating technologies both for NASA missions and other uses. JPL's contingent of scientific researchers was equally busy coordinating the science activities of our missions or pursuing independent investigations. None of this would be possible without the support of world-class business and administrative teams. All of our missions in one way or another support our nations Vision for Space Exploration, which envisages a gradually widening robotic and human presence across the solar system in the years ahead. The year was not without its challenges. NASA set forth to implement the Vision for Space Exploration, which resulted in some flight projects and technology efforts being terminated. To adjust to this new direction, it was necessary for us to reduce the JPL workforce by about five percent. Taking steps like this is painful, but we tried to make the process as orderly as possible. In the end, the adjustments made have left JPL on a healthy footing for the years ahead.

Jet Propulsion Laboratory (JPL)↗
NASA NTRS2018

Hybridized Agile Software Development of Flight Control Team Tools for International Space Station's Payload Operations Integration Center

Ground systems operations at the National Aeronautics and Space Administration's (NASA) Payload Operations and Integration Center (POIC) at Marshall Space Flight Center (MSFC) recently increased via a High Operations Tempo (HOT) initiative, in order to support more science activities with a fourth crew member on the International Space Station (ISS). The Flight Control Team's (FCT) need to support this increasing pace of payload science operations was the impetus for creating a series of new tools. While their need was clear, the full scope and user experience for each tool was not as well-understood, thus establishing a fixed set of initial requirements was not feasible. A hybridized Agile Software Development (ASD) paradigm was created to take advantage of this uncertainty, plan for it, permit the exploration of novel concepts, and also facilitate a rapid and flexible response to inevitably changing requirements. The POIC's hybridized ASD approach places preeminent focus on providing customer value through the delivery of high quality, customer-focused solutions in short timeframes. This has been successfully achieved through creating unprecedented modes of cooperation and collaboration between operations and software development teams, frequent user evaluations of the software with well-defined feedback mechanisms, increased human factors involvement, and a dedication to successful outcomes by the whole of the POIC. Since space science operations and software development are not typically so closely linked, this paper discusses an approach that offers an optimal way to provide an increased return on investment and a faster time-to-completion than traditional software development paradigms, while aiming at delivering high quality products and customer-driven value.

Albers, Cerese M.↗
NASA NTRS2014

Human Mars Surface Science Operations

Human missions to the surface of Mars will have challenging science operations. This paper will explore some of those challenges, based on science operations considerations as part of more general operational concepts being developed by NASA's Human Spaceflight Architecture (HAT) Mars Destination Operations Team (DOT). The HAT Mars DOT has been developing comprehensive surface operations concepts with an initial emphasis on a multi-phased mission that includes a 500-day surface stay. This paper will address crew science activities, operational details and potential architectural and system implications in the areas of (a) traverse planning and execution, (b) sample acquisition and sample handling, (c) in-situ science analysis, and (d) planetary protection. Three cross-cutting themes will also be explored in this paper: (a) contamination control, (b) low-latency telerobotic science, and (c) crew autonomy. The present traverses under consideration are based on the report, Planning for the Scientific Exploration of Mars by Humans1, by the Mars Exploration Planning and Analysis Group (MEPAG) Human Exploration of Mars-Science Analysis Group (HEM-SAG). The traverses are ambitious and the role of science in those traverses is a key component that will be discussed in this paper. The process of obtaining, handling, and analyzing samples will be an important part of ensuring acceptable science return. Meeting planetary protection protocols will be a key challenge and this paper will explore operational strategies and system designs to meet the challenges of planetary protection, particularly with respect to the exploration of "special regions." A significant challenge for Mars surface science operations with crew is preserving science sample integrity in what will likely be an uncertain environment. Crewed mission surface assets -- such as habitats, spacesuits, and pressurized rovers -- could be a significant source of contamination due to venting, out-gassing and cleanliness levels associated with crew presence. Low-latency telerobotic science operations has the potential to address a number of contamination control and planetary protection issues and will be explored in this paper. Crew autonomy is another key cross-cutting challenge regarding Mars surface science operations, because the communications delay between earth and Mars could as high as 20 minutes one way, likely requiring the crew to perform many science tasks without direct timely intervention from ground support on earth. Striking the operational balance between crew autonomy and earth support will be a key challenge that this paper will address.

Bobskill, Marianne R.↗
DOE OSTI2019

Advancing Fusion with Machine Learning Research Needs Workshop

The pursuit of fusion energy has required extensive experimental and theoretical science activities to develop the knowledge needed that will enable design of successful fusion power plants. Even today, following decades of research in many key areas including plasma physics and material science, much remains to be learned to enable optimization of the tokamak or other paths to fusion energy. Data science methods from the fields of machine learning and artificial intelligence (ML/AI) offer opportunities for enabling or accelerating progress toward the realization of fusion energy by maximizing the amount and usefulness of information extracted from experimental and simulation output data. Jointly supported by the Department of Energy Offices of Fusion Energy Science (FES) and Advanced Scientific Computing Research (ASCR), a workshop was organized to identify Priority Research Opportunities (PRO’s) for application of ML/AI methods to enable accelerated solution of fusion problems. The resulting “Advancing Fusion with Machine Learning Research Needs Workshop,” held in Gaithersburg, MD, April 30 – May 2, 2019, brought together ~ 60 experts in fields spanning fusion science, data science, statistical inference and mathematics, machine learning, and artificial intelligence, along with DOE program managers and technical experts, to identify key PRO’s.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗
NASA NTRS2014

Rodent Research on the International Space Station - A Look Forward

Rodent Research on the International Space Station (ISS) is one of the highest priority science activities being supported by NASA and is planned for up to two flights per year. The first Rodent Research flight, Rodent Research-1 (RR-1) validates the hardware and basic science operations (dissections and tissue preservation). Subsequent flights will add new capabilities to support rodent research on the ISS. RR-1 will validate the following capabilities: animal husbandry for up to 30 days, video downlink to support animal health checks and scientific analysis, on-orbit dissections, sample preservation in RNA. Later and formalin, sample transfer from formalin to ethanol (hindlimbs), rapid cool-down and subsequent freezing at -80 of tissues and carcasses, sample return and recovery. RR-2, scheduled for SpX-6 (Winter 20142015) will add the following capabilities: animal husbandry for up to 60 days, RFID chip reader for individual animal identification, water refill and food replenishment, anesthesia and recovery, bone densitometry, blood collection (via cardiac puncture), blood separation via centrifugation, soft tissue fixation in formalin with transfer to ethanol, and delivery of injectable drugs that require frozen storage prior to use. Additional capabilities are also planned for future flights and these include but are not limited to male mice, live animal return, and the development of experiment unique equipment to support science requirements for principal investigators that are selected for flight. In addition to the hardware capabilities to support rodent research the Crew Office has implemented a training program in generic rodent skills for all USOS crew members during their pre-assignment training rotation. This class includes training in general animal handling, euthanasia, injections, and dissections. The dissection portion of this training focuses on the dissection of the spleen, liver, kidney with adrenals, brain, eyes, and hindlimbs. By achieving and maintaining proficiency in these basic skills as part of the nominal astronaut training curriculum this allows the rodent research program to focus the mission specific crew training on scientific requirements of research and operations flow.

Experimental capabilities↗