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Exploration Medical Capability - Advancing Medical System Design and Risk-Informed Decision Making for Deep Space Exploration

BACKGROUND: Within NASA’s Human Research Program, the Exploration Medical Capability (ExMC) Element has three primary focus areas: clinical and scientific research, systems engineering and trade space analysis, and technology development and demonstrations. These focus areas feed into the overarching goal of enabling progressively Earth-Independent Medical Operations (EIMO), a new paradigm that will be necessary for future Artemis and Mars medical and vehicle systems. This EIMO end state aligns with NASA’s Moon to Mars Objectives, which clearly outline the need for NASA deep space exploration missions to reduce their reliance upon Earth and become increasingly autonomous, in preparation for the first human Mars mission. OVERVIEW: To advance exploration medical systems and ultimately, integrated crew health and performance systems, ExMC’s portfolio includes: funding ground development & testing of novel medical capabilities; creation of new approaches for the development of medical protocols and procedures; deployment of innovative technologies into analog environments; technology demonstrations in spaceflight; and eventual transition to operations of new capabilities for deep space exploration missions. The portfolio also includes: pharmaceutical research targeting stability, pharmacokinetics, and pharmacodynamics; integrated data architectures and clinical decision support tools; and systems engineering and trade space analysis tools to assist NASA in the development of future medical system models as well as the medical system requirements that can serve as a foundation for deep space exploration missions. All of these investments are done in a collaborative and coordinated fashion with other NASA stakeholders, such as the Environmental Control and Life Support Systems – Crew Health and Performance System Capability Leadership Team and the Health and Medical Technical Authority. DISCUSSION: In this presentation, ExMC will provide an overview of our work from across our portfolio, all of which will inform future EIMO efforts at NASA. ExMC’s research and development investments are targeted to reduce the human system risks associated with deep space exploration to the Moon and Mars.

Kris Lehnhardt↗

Update On NASA ISRU Plans, Priorities, and Activities

Introduction: In 2022, The National Aeronautics and Space Administration (NASA) of the United States of America (US) Space Technology Mission Directorate (STMD) released the In Situ Resource Utilization (ISRU) Envisioned Future Priorities (EFP), along with other discipline EFPs, to the public in April for comment. The ISRU EFP is a ‘strategic’ level document to provide guidance to NASA, industry, academia, and international space agencies on the long-term vision for ISRU, as well as the goals, objectives, state of the art, gaps, and near-term priorities to achieve the vision. Since the release, a significant number of comments have been received through a Request for Information, and interactions at meetings and conferences. Based on comments received, as well as changes to the NASA budget, the release of the NASA Moon to Mars (M2M) Objectives at the International Aeronautical Congress (IAC) in Paris, and evolving plans for the Artemis program, an updated version of the ISRU EFP was created and released in March, 2023.

ISRU↗

Preliminary design of a universal Martian lander

In the next 25 years, mankind will be undertaking yet another giant leap forward in the exploration of the solar system: a manned mission to Mars. This journey will provide important information on the composition and history of both Mars and the Solar System. A manned mission will also provide the opportunity to study how humans can adapt to long term space flight conditions and the Martian environment. As part of the NASA/USRA program, nineteen West Virginia University students conducted a preliminary design of a manned Universal Martian Lander (UML). The UML's design will provide a 'universal' platform, consisting of four modules for living and laboratory experiments and a liquid-fuel propelled Manned Ascent Return Vehicle (MARV). The distinguishing feature of the UML is the 'universal' design of the modules which can be connected to form a network of laboratories and living quarters for future missions thereby reducing development and production costs. The WVU design considers descent to Mars from polar orbit, a six month surface stay, and ascent for rendezvous. The design begins with an unmanned UML landing at Elysium Mons followed by the manned UML landing nearby. During the six month surface stay, the eight modules will be assembled to form a Martian base where scientific experiments will be performed. The mission will also incorporate hydroponic plant growth into a Controlled Ecological Life Support System (CELSS) for water recycling, food production, and to counteract psychological effects of living on Mars. In situ fuel production for the MARV will be produced from gases in the Martian atmosphere. Following surface operations, the eight member crew will use the MARV to return to the Martian Transfer Vehicle (MTV) for the journey home to Earth.

Norman, Timothy L.↗

NASA's Needs for Biomaterials within the HEDS Initiative

The part to be played by materials scientists to further NASA's exploration missions cannot be underestimated. To quote Jerome Groopman (New Yorker, February 14, 2000), "The rocket science will be the easy part". The four main risks on the Critical Path Road Map during a three-year sojourn to Mars are osteoporosis, psychological problems, radiation induced cancer and acute medical trauma. NASA's microgravity materials science program has investigations in membrane fabrication, bone growth and materials for radiation protection. These programs will be reviewed in the context of the four main risks, as will other potential uses of biomaterials and applications of biomimetic processing.

Gillies, Donald C.↗

Upcoming and Future Missions in the Area of Infrared Astronomy: Spacecraft and Ground-based Observations

The IRIS instrument on the Voyager spacecrafts made major discoveries with regard to the giant planets, their moons and rings and paved the way for future infrared observations for planetary missions within our solar system. The CIRS instrument of Cassini with much greater spectral-spatial resolution and sensitivity than that provided by IRIS is now rapidly approaching the Saturnian system with orbit insertion on July 1, 2004, for which CIRS is expected to provide an order of magnitude advance beyond that provided by IRIS. The Mars program is also presently dominated by infrared observations in the near to mid-infrared spectral bands for missions such as Mars Global Surveyor and its TES instrument and Odyssey with its THEMIS instrument. In the case of Earth science we have such missions as TIMED, which makes infrared observations of the thermosphere using the SABER instrument. With the newly formed New Frontiers Program we have the opportunity for $650M missions such as Kuiper Belt-Pluto Explorer and Jupiter Polar Orbiter with Probes. Under the Flagship line, once per decade, we have the opportunity for $1B missions for which Europa is presently being considered; for this mission infrared measurements could look for hot spots within the maze of cracks and faults on Europa s surface. On Kuiper Belt- Pluto there is an imaging near-IR spectrometer called LEISA. Another mission on the horizon is Titan Orbiter Aerorover Mission (TOAM) for which there is planned a state-of-art version of CIRS called TIRS on the orbiter that will map out the atmospheric composition with unprecedented wavelength coverage and spectral-spatial resolution. This instrument will also provide temperature maps of the surface of Titan to look for hot spots where life may form. On the same mission there will be a descent imager on the Aerorover (i.e., balloon) similar to that provided by LEISA on the Pluto mission to provide compositional-topographical maps of Titan s surface. Other future mission will also be discussed. Improved thermal detectors could have important applications in solar physics, specifically in the detection of far-IR synchrotron emission from energetic electrons in solar flares. For infrared astronomy we have missions like SIRTF and JWST, which will cover the spectral range from near-IR to far-IR in the search and probing of both new and old planetary systems in our galaxy and the measurement of the most distant galaxies of our universe. SIRTF is scheduled to be launched in August 2003, while JWST will be launched next decade. Another mission is TPF, which will use interferometer techniques at infrared wavelengths to search for planetary systems beyond 2010. With regard to ground based telescopes we have, for example, the twin 10 meter Keck telescopes and the IRTF telescope at Mauna Kea. The Keck telescopes are presently using interferometer techniques. Over the next several decades there are plans for 50 meter to 200 meter telescopes providing near-IR to far-IR measurements with the eventual plan to combine all telescopes using interferometer techniques to provide unprecedented spectral-spatial resolution and sensitivity.

Sittler, E. C., Jr.↗

Simple, Robust Cryogenic Propellant Depot for Near Term Applications

The ability to refuel cryogenic propulsion stages on-orbit provides an innovative paradigm shift for space transportation supporting National Aeronautics and Space Administration s (NASA) Exploration program as well as deep space robotic, national security and commercial missions. Refueling enables large beyond low Earth orbit (LEO) missions without requiring super heavy lift vehicles that must continuously grow to support increasing mission demands as America s exploration transitions from early Lagrange point missions to near Earth objects (NEO), the lunar surface and eventually Mars. Earth-to-orbit launch can be optimized to provide competitive, cost-effective solutions that allow sustained exploration. This paper describes an experimental platform developed to demonstrate the major technologies required for fuel depot technology. This test bed is capable of transferring residual liquid hydrogen (LH2) or liquid oxygen (LO2) from a Centaur upper stage, and storage in a secondary tank for up to one year on-orbit. A dedicated, flight heritage spacecraft bus is attached to an Evolved Expendable Launch Vehicle (EELV) Secondary Payload Adapter (ESPA) ring supporting experiments and data collection. This platform can be deployed as early as Q1 2013. The propellant depot design described in this paper can be deployed affordably this decade supporting missions to Earth-Moon Lagrange points and lunar fly by. The same depot concept can be scaled up to support more demanding missions and launch capabilities. The enabling depot design features, technologies and concept of operations are described.

McLean, Christopher↗

Logistics Lessons Learned in NASA Space Flight

The Vision for Space Exploration sets out a number of goals, involving both strategic and tactical objectives. These include returning the Space Shuttle to flight, completing the International Space Station, and conducting human expeditions to the Moon by 2020. Each of these goals has profound logistics implications. In the consideration of these objectives,a need for a study on NASA logistics lessons learned was recognized. The study endeavors to identify both needs for space exploration and challenges in the development of past logistics architectures, as well as in the design of space systems. This study may also be appropriately applied as guidance in the development of an integrated logistics architecture for future human missions to the Moon and Mars. This report first summarizes current logistics practices for the Space Shuttle Program (SSP) and the International Space Station (ISS) and examines the practices of manifesting, stowage, inventory tracking, waste disposal, and return logistics. The key findings of this examination are that while the current practices do have many positive aspects, there are also several shortcomings. These shortcomings include a high-level of excess complexity, redundancy of information/lack of a common database, and a large human-in-the-loop component. Later sections of this report describe the methodology and results of our work to systematically gather logistics lessons learned from past and current human spaceflight programs as well as validating these lessons through a survey of the opinions of current space logisticians. To consider the perspectives on logistics lessons, we searched several sources within NASA, including organizations with direct and indirect connections with the system flow in mission planning. We utilized crew debriefs, the John Commonsense lessons repository for the JSC Mission Operations Directorate, and the Skylab Lessons Learned. Additionally, we searched the public version of the Lessons Learned Information System (LLIS) and verified that we received the same result using the internal version of LLIS for our logistics lesson searches. In conducting the research, information from multiple databases was consolidated into a single spreadsheet of 300 lessons learned. Keywords were applied for the purpose of sorting and evaluation. Once the lessons had been compiled, an analysis of the resulting data was performed, first sorting it by keyword, then finding duplication and root cause, and finally sorting by root cause. The data was then distilled into the top 7 lessons learned across programs, centers, and activities.

Evans, William A.↗

High energy astrophysics 21st century workshop 'Space Capabilities in the 21st Century'

An overview of 20th-century NASA accomplishments and of the infrastructure and technology that NASA plans to have in place in the 21st century is presented. Attention is given to the Great Observatories Program, AXAF, the Space Infrared Telescope Facility, the Cosmic Background Explorer, the Small Explorers Program, the Large Area Modular Array of Reflectors, and the X-Ray Background Survey Spectrometer. Also discussed are earth-to-orbit communication links, transportation in the 1990s, the evolution of the space infrastructure, and the Space Station Freedom. Consideration is given to the possibilities of the 21st-century infrastructure, with emphasis on exploration on Mars and the moon. Topics addressed include telecommunications, navigation, information management, and 21st-century space science.

Rhome, Robert C.↗

Developing Nontraditional Partnerships to Disseminate the Space Science Story

NASA Space Science Days (NSSD) was established in 2004 to bring the story of the Mars Exploration Rovers (MER) to a community far removed from areas NASA traditionally serves. The original NSSD invited 400 5th and 8th graders from the Texas Rio Grande Valley area to the University of Texas Brownsville campus to participate in a one day Saturday event filled with information about MER with related hands on activities. Currently the program has grown to over 700 5th and 8th grade participants who are mentored by trained university students from several Texas universities and community colleges and growing to include universities from throughout the U.S. A collaboration between three major institutions: The NASA Johnson Space Center (JSC) Astromaterials Research and Exploration Science Directorate (ARES), the Society of Hispanic Professional Engineers/Advancing Hispanic Excellence in Technology Engineering, Math, and Science, (SHPE/AHETEMS), and the University of Texas at Brownsville (UTB) has been established to enable the dissemination of Solar System related educational materials throughout the U.S. Already in its 8th year, UTB has developed and tested a NSSD model that has successfully disseminated space science materials to students throughout South Texas Rio Grande Valley. With this newly formed collaboration this model s expansion will allow trained SHPE students and professionals to conduct events throughout its established nation-wide delivery systems. Each year a new NSSD site will be established through an application process solicited from SHPE student and professional chapters. Once a chapter is awarded, upper-level high school and university students will travel to NASA- JSC for a two day workshop where students learn about the current year s theme and are trained to present hands-on activities related to the theme. Additional training by ARES and UTB occurs one month before the new event in their own communities. Both local middle school teachers and mentors are trained locally. This allows the teachers time to prepare their students with the background material for NSSD and give the mentors time to decide which activity they feel comfortable with to lead. Several events using this process have already been successful and an increase in interest from SHPE chapters wanting to establish their NSSD event is growing.

Galindo, Charles↗

Generalizable Skills and Knowledge for Exploration Missions

This report describes research conducted under Cooperative Agreement 80NSSC18K0042 for the Human Factors and Behavioral Performance Element, Human Research Program, located at the National Aeronautics and Space Administration’s (NASA) Johnson Space Center. The research addresses the Risk of Inadequate Mission, Process, and Task Design and the Risk of Performance Errors Due to Training Deficiencies during exploration-class space missions by identifying the tasks that will be conducted by human crew during an expedition to Mars and the abilities, skills, and knowledge that will be required of crew members. By focusing on an expedition to Mars, we have considered the extremes of what is possible for human space exploration during the first half of the 21st Century and accommodated the human requirements for missions to asteroids, Cis-Lunar orbit, and a return to the Moon.

Stuster, Jack↗

Updated and Risk-Informed Process for Launching Space Nuclear Systems in the United States

The “Presidential Memorandum on Reinvigorating America’s Human Space Exploration Program,” (Space Policy Directive-1) charges NASA to: “Lead an innovative and sustainable program of exploration with commercial and international partners to enable human expansion across the solar system and to bring back to Earth new knowledge and opportunities. Beginning with missions beyond low-Earth orbit, the United States will lead the return of humans to the Moon for long-term exploration and utilization, followed by human missions to Mars and other destinations."

Space Policy↗

Program of solar wind data analysis utilizing data from Pioneer 6, Mariner 5 and explorer 35

A combined data analysis and theoretical program aimed at interpreting and utilizing solar wind data obtained from Pioneer 6, Mariner 5, and Explorer 35 has been completed. A theoretical model of the radial dependence of large scale solar wind inhomogeneities was developed and used to map solar wind variations measured by Explorer 35 to various heliocentric distances and to the orbits of Mercury, Venus, and Mars. The model was also used to determine power spectra velocity, density and temperature variations of 20 R sub s from spectra obtained from the Mariner 5 data at an average heliocentric distance of 180 R sub s. Five stream-stream interaction events in the Pioneer 6 data were analyzed which confirmed the picture of a spiral compression ridge interfacing the two streams and the associated east-west deflections of the solar wind flow. Magnetopause crossings observed in Explorer 35 plasma data were used to develop statics on boundary motions at lunar distance. A study of the geomagnetic disturbance field asymmetry was performed and a model of disturbance field from a partial ring current was developed.

Siscoe, G. L.↗

Experimental and simulation study results of an Adaptive Video Guidance System /AVGS/

Studies relating to stellar-body exploration programs have pointed out the need for an adaptive guidance scheme capable of providing automatic real-time guidance and site selection capability. For the case of a planetary lander, without such guidance, targeting is limited to what are believed to be generally benign areas in order to ensure a reasonable landing-success probability. Typically, the Mars Viking Lander will be jeopardized by obstacles exceeding 22 centimers in diameter. The benefits of on-board navigation and real-time selection of a landing site and obstacle avoidance have been demonstrated by the Apollo lunar landings, in which man performed the surface sensing and steering functions. Therefore, an Adaptive Video Guidance System (AVGS) has been developed, bread-boarded, and flown on a six-degree-of-freedom simulator.

Schappell, R. T.↗

Space Station Freedom growth power requirements

Options and scenarios for the evolution of Space Station Freedom beyond the current baseline have been established and analyzed at NASA Langley Research Center to identify growth requirements for the program's Preliminary Requirements Review (PRR). Time-phase requirements for electrical power and other critical resources were determined based upon the future needs of the science, technology and commercial users. In addition, impacts and resource growth were determined for the utilization of station as a transportation node in support of human exploration initiatives to the moon and/or Mars. The set of requirements chosen for the PRR were selected on the basis of their adequacy in accommodating each of the evolution options and scenarios within each option, thereby maximizing future flexibility. In the case of electrical power, growth to 275 kW (average) was determined to be adequate for evolutionary missions and station housekeeping growth, given projections of future earth-to-orbit transportation capabilities.

Meredith, B. D.↗

Radioisotope Power Systems Program: A Program Overview

NASA's Radioisotope Power Systems (RPS) Program continues to plan, mature research in energy conversion, and partners with the Department of Energy (DOE) to make RPS ready and available to support the exploration of the solar system in environments where the use of conventional solar or chemical power generation is impractical or impossible to meet potential future mission needs. Recent programs responsibilities include providing investment recommendations to NASA stakeholders on emerging thermoelectric and Stirling energy conversion technologies and insight on NASA investments at DOE in readying a generator for the Mars 2020 mission. This presentation provides an overview of the RPS Program content and status and the approach used to maintain the readiness of RPS to support potential future NASA missions.

Nuclear↗

Adopting an Objectives-Driven Assurance Case Approach for Achieving Space Flight Mission Planetary Protection Objectives

Traditionally, the National Aeronautics and Space Administration (NASA) has utilized prescriptive technical and process requirements to ensure safety and mission assurance performance objectives for planetary protection are achieved during space flight missions. While prescriptive requirements may be easier to communicate and manage throughout the systems engineering process, the highly constrained nature of prescriptive requirements can limit the ability to take advantage of cost-saving opportunities and offer limited ability to explore other options or alternative designs, processes, and methods. It can also be difficult to develop prescriptive requirements for objectives that are probabilistic in nature or that cannot be satisfied by direct verification. In contrast, the development of an assurance case allows for a compelling, comprehensible, and valid argument to be developed with supporting evidence that shows safety and mission assurance objectives have been satisfied. Analogous to how patent applications are constructed for inventions, an assurance case has a high-level claim of meeting a safety and mission assurance objective, followed by a more specific set of sub-claims and technical evidence which supports the claims. The objectives-driven assurance case approach allows for a better understanding and exploration of the trade space, more flexibility to balance trades, and the ability to realize and implement technical and process innovations for resource, time, and cost savings. The assurance case is a living case that evolves over the entire program life cycle. Recently, NASA’s Office of Planetary Protection (OPP) has adopted the assurance case approach as an acceptable methodology for demonstrating avoidance of contamination of target solar system bodies explored by NASA space flight missions. This methodology has been incorporated into NASA’s new technical standard for planetary protection and is currently being utilized by the Mars Sample Return campaign for safe sample containment during sample return.

Assurance Case↗

Returning to the Moon: NASA's Artemis Missions

With Artemis missions, NASA will establish the first long-term presence on the Moon. NASA’s goal is to land the first woman on the Moon and return them safely to Earth. The exploration and settlement on Moon will enable the next giant leap - sending the first astronauts to Mars. During the next era of human exploration, we will discover life-saving, Earth-changing science and technology along the way. Artemis missions will enable a growing lunar economy by fueling new industries, supporting job growth, and furthering the demand for a skilled workforce. In her seminar, Dr. Agrawal will provide an overview of the Artemis program, its different elements and a brief description of some of the technical advancements that have been made to enable the first Artemis 1 flight. She will then provide an overview of the Orion program whose charter is to multiple spacecraft for Artemis missions and discuss the ongoing activities at NASA Ames in support of Orion and Artemis programs.

Artemis↗

Returning to the Moon: NASA's Artemis Missions

With Artemis missions, NASA will establish the first long-term presence on the Moon. NASA’s goal is to land the first woman on the Moon and return them safely to Earth. The exploration and settlement on Moon will enable the next giant leap - sending the first astronauts to Mars. During the next era of human exploration, we will discover life-saving, Earth-changing science and technology along the way. Artemis missions will enable a growing lunar economy by fueling new industries, supporting job growth, and furthering the demand for a skilled workforce. In her seminar, Dr. Agrawal will provide an overview of the Artemis program, its different elements and a brief description of some of the technical advancements that have been made to enable the first Artemis 1 flight. She will then provide an overview of the Orion program whose charter is to multiple spacecraft for Artemis missions and discuss the ongoing activities at NASA Ames in support of Orion and Artemis programs.

Artemis↗