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At least 1,081 records · Page 60

TH-CD-207A-03: A Surface Deformation Driven Respiratory Model for Organ Motion Tracking in Lung Cancer Radiotherapy

Purpose: To propose and validate a novel real-time surface-mesh-based internal organ-external surface motion and deformation tracking method for lung cancer radiotherapy. Methods: Deformation vector fields (DVFs) which characterizes the internal and external motion are obtained by registering the internal organ and tumor contours and external surface meshes to a reference phase in the 4D CT images using a recent developed local topology preserved non-rigid point matching algorithm (TOP). A composite matrix is constructed by combing the estimated internal and external DVFs. Principle component analysis (PCA) is then applied on the composite matrix to extract principal motion characteristics and finally yield the respiratory motion model parameters which correlates the internal and external motion and deformation. The accuracy of the respiratory motion model is evaluated using a 4D NURBS-based cardiac-torso (NCAT) synthetic phantom and three lung cancer cases. The center of mass (COM) difference is used to measure the tumor motion tracking accuracy, and the Dice’s coefficient (DC), percent error (PE) and Housdourf’s distance (HD) are used to measure the agreement between the predicted and ground truth tumor shape. Results: The mean COM is 0.84±0.49mm and 0.50±0.47mm for the phantom and patient data respectively. The mean DC, PE and HD are 0.93±0.01, 0.13±0.03 and 1.24±0.34 voxels for the phantom, and 0.91±0.04, 0.17±0.07 and 3.93±2.12 voxels for the three lung cancer patients, respectively. Conclusions: We have proposed and validate a real-time surface-mesh-based organ motion and deformation tracking method with an internal-external motion modeling. The preliminary results conducted on a synthetic 4D NCAT phantom and 4D CT images from three lung cancer cases show that the proposed method is reliable and accurate in tracking both the tumor motion trajectory and deformation, which can serve as a potential tool for real-time organ motion and deformation monitoring in lung cancer radiotherapy. This work is supported in part by grant from VARIAN MEDICAL SYSTEMS INC, the National Natural Science Foundation of China (no 81428019 and no 81301940), the Guangdong Natural Science Foundation (2015A030313302)and the 2015 Pearl River S&T Nova Program of Guangzhou (201506010096).

60 APPLIED LIFE SCIENCES↗

In-process monitoring and prediction of droplet quality in droplet-on-demand liquid metal jetting additive manufacturing using machine learning

Abstract In droplet-on-demand liquid metal jetting (DoD-LMJ) additive manufacturing, complex physical interactions govern the droplet characteristics, such as size, velocity, and shape. These droplet characteristics, in turn, determine the functional quality of the printed parts. Hence, to ensure repeatable and reliable part quality it is necessary to monitor and control the droplet characteristics. Existing approaches for in-situ monitoring of droplet behavior in DoD-LMJ rely on high-speed imaging sensors. The resulting high volume of droplet images acquired is computationally demanding to analyze and hinders real-time control of the process. To overcome this challenge, the objective of this work is to use time series data acquired from an in-process millimeter-wave sensor for predicting the size, velocity, and shape characteristics of droplets in DoD-LMJ process. As opposed to high-speed imaging, this sensor produces data-efficient time series signatures that allows rapid, real-time process monitoring. We devise machine learning models that use the millimeter-wave sensor data to predict the droplet characteristics. Specifically, we developed multilayer perceptron-based non-linear autoregressive models to predict the size and velocity of droplets. Likewise, a supervised machine learning model was trained to classify the droplet shape using the frequency spectrum information contained in the millimeter-wave sensor signatures. High-speed imaging data served as ground truth for model training and validation. These models captured the droplet characteristics with a statistical fidelity exceeding 90%, and vastly outperformed conventional statistical modeling approaches. Thus, this work achieves a practically viable sensing approach for real-time quality monitoring of the DoD-LMJ process, in lieu of the existing data-intensive image-based techniques.

Gaikwad, Aniruddha (ORCID:0000000285642621)↗

Ultrasonic Model-Based Iterative Reconstruction with Spatially Variant Regularization for One-Sided Non-Destructive Evaluation

One-sided ultrasonic non-destructive evaluation (UNDE) uses ultrasound signals to investigate and inspect structures that are only accessible from one side. A widely used reconstruction technique in UNDE is the synthetic aperture focusing technique (SAFT). SAFT produces fast reconstruction and reasonable images for simple structures. However, for large complex structures, SAFT reconstructions suffer from noise and artifacts. To resolve some of the drawbacks of SAFT, an ultrasonic model-based iterative reconstruction (MBIR) algorithm, a method based on Bayesian estimation, was proposed that showed significant enhancement over SAFT in reducing noise and artifacts. In this paper, we build on previous investigations of the use of MBIR reconstruction on ultrasound data by proposing a spatially varying prior-model to account for artifacts from deeper regions and a 3D regularizer to account for correlations between scans from adjacent regions. We demonstrate that the use of the new prior model in MBIR can significantly improve reconstructions compared to SAFT and the previously proposed MBIR technique.

Almansouri, Hani↗

Performance of today’s dual energy CT and future multi energy CT in virtual non-contrast imaging and in iodine quantification: A simulation study

Purpose: To study the performance of different dual energy computed tomography (DECT) techniques, which are available today, and future multi energy CT (MECT) employing novel photon counting detectors in an image-based material decomposition task. Methods: The material decomposition performance of different energy-resolved CT acquisition techniques is assessed and compared in a simulation study of virtual non-contrast imaging and iodine quantification. The material-specific images are obtained via a statistically optimal image-based material decomposition. A projection-based maximum likelihood approach was used for comparison with the authors’ image-based method. The different dedicated dual energy CT techniques are simulated employing realistic noise models and x-ray spectra. The authors compare dual source DECT with fast kV switching DECT and the dual layer sandwich detector DECT approach. Subsequent scanning and a subtraction method are studied as well. Further, the authors benchmark future MECT with novel photon counting detectors in a dedicated DECT application against the performance of today’s DECT using a realistic model. Additionally, possible dual source concepts employing photon counting detectors are studied. Results: The DECT comparison study shows that dual source DECT has the best performance, followed by the fast kV switching technique and the sandwich detector approach. Comparing DECT with future MECT, the authors found noticeable material image quality improvements for an ideal photon counting detector; however, a realistic detector model with multiple energy bins predicts a performance on the level of dual source DECT at 100 kV/Sn 140 kV. Employing photon counting detectors in dual source concepts can improve the performance again above the level of a single realistic photon counting detector and also above the level of dual source DECT. Conclusions: Substantial differences in the performance of today’s DECT approaches were found for the application of virtual non-contrast and iodine imaging. Future MECT with realistic photon counting detectors currently can only perform comparably to dual source DECT at 100 kV/Sn 140 kV. Dual source concepts with photon counting detectors could be a solution to this problem, promising a better performance.

60 APPLIED LIFE SCIENCES↗

Reconstructing porous media using generative flow networks

One area of intense scientific interest for the study of sandstones, carbonates, and shale at the pore scale is the use of limited image and petrophysical data to generate multiple realizations of a rock’s pore structure. Such images aid efforts to quantify uncertainty in petrophysical properties, including porosity–permeability transforms. We develop and evaluate a deep learning-based method to synthesize porous media volumes using a so-called generative flow model trained on x-ray microscope images of rock texture and pore structure. These models are optimized on a log-likelihood objective and they synthesize large and realistic three-dimensional images. Further, we demonstrate the rapid generation of sandstone image volumes that display realism as gauged by quantitative comparison of topological features using Minkowski functionals of porosity, specific surface area, and the Euler–Poincaré characteristic (i.e., pore connectivity). We also evaluate the single-phase permeability using Navier–Stokes and lattice Boltzmann methods and show that transport properties of the generated samples match measured trends.

58 GEOSCIENCES↗

Principled halftoning based on human vision models

When models of human vision adequately measure the relative quality of candidate halftonings of an image, the problem of halftoning the image becomes equivalent to the search problem of finding a halftone that optimizes the quality metric. Because of the vast number of possible halftones, and the complexity of image quality measures, this principled approach has usually been put aside in favor of fast algorithms that seem to perform well. We find that the principled approach can lead to a range of useful halftoning algorithms, as we trade off speed for quality by varying the complexity of the quality measure and the thoroughness of the search. High quality halftones can be obtained reasonably quickly, for example, by using as a measure the vector length of the error image filtered by a contrast sensitivity function, and, as the search procedure, the sequential adjustment of individual pixels to improve the quality measure. If computational resources permit, simulated annealing can find nearly optimal solutions.

Mulligan, Jeffrey B.↗

Evaluating iterative reconstruction performance in computed tomography

Purpose: Iterative reconstruction (IR) offers notable advantages in computed tomography (CT). However, its performance characterization is complicated by its potentially nonlinear behavior, impacting performance in terms of specific tasks. This study aimed to evaluate the performance of IR with both task-specific and task-generic strategies. Methods: The performance of IR in CT was mathematically assessed with an observer model that predicted the detection accuracy in terms of the detectability index (d′). d′ was calculated based on the properties of the image noise and resolution, the observer, and the detection task. The characterizations of image noise and resolution were extended to accommodate the nonlinearity of IR. A library of tasks was mathematically modeled at a range of sizes (radius 1–4 mm), contrast levels (10–100 HU), and edge profiles (sharp and soft). Unique d′ values were calculated for each task with respect to five radiation exposure levels (volume CT dose index, CTDI{sub vol}: 3.4–64.8 mGy) and four reconstruction algorithms (filtered backprojection reconstruction, FBP; iterative reconstruction in imaging space, IRIS; and sinogram affirmed iterative reconstruction with strengths of 3 and 5, SAFIRE3 and SAFIRE5; all provided by Siemens Healthcare, Forchheim, Germany). The d′ values were translated into the areas under the receiver operating characteristic curve (AUC) to represent human observer performance. For each task and reconstruction algorithm, a threshold dose was derived as the minimum dose required to achieve a threshold AUC of 0.9. A task-specific dose reduction potential of IR was calculated as the difference between the threshold doses for IR and FBP. A task-generic comparison was further made between IR and FBP in terms of the percent of all tasks yielding an AUC higher than the threshold. Results: IR required less dose than FBP to achieve the threshold AUC. In general, SAFIRE5 showed the most significant dose reduction potentials (11–54 mGy, 77%–84%), followed by SAFIRE3 (7–36 mGy, 50%–61%) and IRIS (6–26 mGy, 37%–50%). The dose reduction potentials highly depended on task size and task contrast, with tasks of lower contrasts and smaller sizes, i.e., more challenging tasks, indicating higher dose reductions. Softer edge profile showed higher dose reduction potentials with SAFIRE3 and SAFIRE5, but not with IRIS. The task-generic comparison between IR and FBP demonstrated the overall superiority of IR performance, as IR allowed a larger percent of tasks to exceed the threshold AUC: IRIS, 8%–12%; SAFIRE3, 10%–16%; and SAFIRE5, 20%–33%. The improvement with IR was generally more pronounced at lower dose levels. Conclusions: Expanding beyond traditional contrast and noise based assessments of IR, we performed both task-specific and task-generic evaluations of IR performance. The task-specific evaluation demonstrated the dependency of IR’s dose reduction potential on task attributes, which can be employed to optimize IR for clinical indications with specific range of size and contrast. The task-generic evaluation demonstrated IR’s overall superiority over FBP in terms of the range of tasks exceeding a threshold performance level, which can be employed for general comparisons between algorithms.

60 APPLIED LIFE SCIENCES↗

Sub-10 second fly-scan nano-tomography using machine learning

Abstract X-ray computed tomography is a versatile technique for 3D structure characterization. However, conventional reconstruction algorithms require that the sample not change throughout the scan, and the timescale of sample dynamics must be longer than the data acquisition time to fulfill the stable sample requirement. Meanwhile, concerns about X-ray-induced parasite reaction and sample damage have driven research efforts to reduce beam dosage. Here, we report a machine-learning-based image processing method that can significantly reduce data acquisition time and X-ray dose, outperforming conventional approaches like Filtered-Back Projection, maximum-likelihood, and model-based maximum-a-posteriori probability. Applying machine learning, we achieve ultrafast nano-tomography with sub-10 second data acquisition time and sub-50 nm pixel resolution in a transmission X-ray microscope. We apply our algorithm to study dynamic morphology changes in a lithium-ion battery cathode under a heating rate of 50 o C min −1 , revealing crack self-healing during thermal annealing. The proposed method can be applied to various tomography modalities.

36 MATERIALS SCIENCE↗

Onset Time of Tumor Repopulation for Cervical Cancer: First Evidence From Clinical Data

Purpose: Accelerated tumor repopulation has significant implications in low-dose rate (LDR) brachytherapy. Repopulation onset time remains undetermined for cervical cancer. The purpose of this study was to determine the onset time of accelerated repopulation in cervical cancer, using clinical data. Methods and Materials: The linear quadratic (LQ) model extended for tumor repopulation was used to analyze clinical data and magnetic resonance imaging-based three-dimensional tumor volumetric regression data from 80 cervical cancer patients who received external beam radiotherapy (EBRT) and LDR brachytherapy. The LDR dose was converted to EBRT dose in 1.8-Gy fractions by using the LQ formula, and the total dose ranged from 61.4 to 99.7 Gy. Patients were divided into 11 groups according to total dose and treatment time. The tumor control probability (TCP) was calculated for each group. The least {chi}{sup 2} method was used to fit the TCP data with two free parameters: onset time (T{sub k}) of accelerated repopulation and number of clonogens (K), while other LQ model parameters were adopted from the literature, due to the limited patient data. Results: Among the 11 patient groups, TCP varied from 33% to 100% as a function of radiation dose and overall treatment time. Higher dose and shorter treatment duration were associated with higher TCP. Using the LQ model, we achieved the best fit with onset time T{sub k} of 19 days and K of 139, with uncertainty ranges of (11, 22) days for T{sub k} and (48, 1822) for K, respectively. Conclusion: This is the first report of accelerated repopulation onset time in cervical cancer, derived directly from clinical data by using the LQ model. Our study verifies the fact that accelerated repopulation does exist in cervical cancer and has a relatively short onset time. Dose escalation may be required to compensate for the effects of tumor repopulation if the radiation therapy course is protracted.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

Masking by Gratings Predicted by an Image Sequence Discriminating Model: Testing Models for Perceptual Discrimination Using Repeatable Noise

Adding noise to stimuli to be discriminated allows estimation of observer classification functions based on the correlation between observer responses and relevant features of the noisy stimuli. Examples will be presented of stimulus features that are found in auditory tone detection and visual vernier acuity. using the standard signal detection model (Thurstone scaling), we derive formulas to estimate the proportion of the observers decision variable variance that is controlled by the added noise. one is based on the probability of agreement of the observer with him/herself on trials with the same noise sample. Another is based on the relative performance of the observer and the model. When these do not agree, the model can be rejected. A second derivation gives the probability of agreement of observer and model when the observer follows the model except for internal noise. Agreement significantly less than this amount allows rejection of the model.

Ahumada, Albert J., Jr.↗

Strain and lattice orientation distribution in SiN/Ge complementary metal–oxide–semiconductor compatible light emitting microstructures by quick x-ray nano-diffraction microscopy

This paper presents a study of the spatial distribution of strain and lattice orientation in CMOS-fabricated strained Ge microstripes using high resolution x-ray micro-diffraction. The recently developed model-free characterization tool, based on a quick scanning x-ray diffraction microscopy technique can image strain down to levels of 10{sup −5} (Δa/a) with a spatial resolution of ∼0.5 μm. Strain and lattice tilt are extracted using the strain and orientation calculation software package X-SOCS. The obtained results are compared with the biaxial strain distribution obtained by lattice parameter-sensitive μ-Raman and μ-photoluminescence measurements. The experimental data are interpreted with the help of finite element modeling of the strain relaxation dynamics in the investigated structures.

75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND↗

Random Walks With Tweedie: A Unified View of Score-Based Diffusion Models [In the Spotlight]

We present a concise derivation for several influential score-based diffusion models that relies on only a few textbook results. Diffusion models have recently emerged as powerful tools for generating realistic, synthetic signals—particularly natural images—and often play a role in state-of-the-art algorithms for inverse problems in image processing. While these algorithms are often surprisingly simple, the theory behind them is not, and multiple complex theoretical justifications exist in the literature. Here, in this study, we provide a simple and largely self-contained theoretical justification for score-based diffusion models that is targeted towards the signal processing community. This approach leads to generic algorithmic templates for training and generating samples with diffusion models. We show that several influential diffusion models correspond to particular choices within these templates and demonstrate that alternative, more straightforward algorithmic choices can provide comparable results. This approach has the added benefit of enabling conditional sampling without any likelihood approximation.

97 MATHEMATICS AND COMPUTING↗

Determination of shape anisotropy in embedded low contrast submonolayer quantum dot structures

We describe a procedure for the morphological characterization of hard-to-image submonolayer quantum dot structures. This procedure employs high resolution x-ray diffraction based reciprocal space mapping, accompanied by rigorous diffraction modeling for precise determination of the morphology of submonolayer quantum dots. Our modelling results and experimental data clearly show that the investigated quantum dots are anisotropically elongated along the [110] orientation. Complementary polarization dependent photoluminescence measurements, combined with our previously reported magneto-photoluminescence data, confirm this conclusion. Our formalism enables direct extraction of structural information of complex embedded three-dimensional structures, which, due to their low electron density contrast with respect to the surrounding host matrix, cannot be readily investigated by traditional electron diffraction techniques.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

Low-Cost Evaluation of EO-1 Hyperion and ALI for Detection and Biophysical Characterization of Forest Logging in Amazonia (NCC5-481)

Major uncertainties exist regarding the rate and intensity of logging in tropical forests worldwide: these uncertainties severely limit economic, ecological, and biogeochemical analyses of these regions. Recent sawmill surveys in the Amazon region of Brazil show that the area logged is nearly equal to total area deforested annually, but conversion of survey data to forest area, forest structural damage, and biomass estimates requires multiple assumptions about logging practices. Remote sensing could provide an independent means to monitor logging activity and to estimate the biophysical consequences of this land use. Previous studies have demonstrated that the detection of logging in Amazon forests is difficult and no studies have developed either the quantitative physical basis or remote sensing approaches needed to estimate the effects of various logging regimes on forest structure. A major reason for these limitations has been a lack of sufficient, well-calibrated optical satellite data, which in turn, has impeded the development and use of physically-based, quantitative approaches for detection and structural characterization of forest logging regimes. We propose to use data from the EO-1 Hyperion imaging spectrometer to greatly increase our ability to estimate the presence and structural attributes of selective logging in the Amazon Basin. Our approach is based on four "biogeophysical indicators" not yet derived simultaneously from any satellite sensor: 1) green canopy leaf area index; 2) degree of shadowing; 3) presence of exposed soil and; 4) non-photosynthetic vegetation material. Airborne, field and modeling studies have shown that the optical reflectance continuum (400-2500 nm) contains sufficient information to derive estimates of each of these indicators. Our ongoing studies in the eastern Amazon basin also suggest that these four indicators are sensitive to logging intensity. Satellite-based estimates of these indicators should provide a means to quantify both the presence and degree of structural disturbance caused by various logging regimes. Our quantitative assessment of Hyperion hyperspectral and ALI multi-spectral data for the detection and structural characterization of selective logging in Amazonia will benefit from data collected through an ongoing project run by the Tropical Forest Foundation, within which we have developed a study of the canopy and landscape biophysics of conventional and reduced-impact logging. We will add to our base of forest structural information in concert with an EO-1 overpass. Using a photon transport model inversion technique that accounts for non-linear mixing of the four biogeophysical indicators, we will estimate these parameters across a gradient of selective logging intensity provided by conventional and reduced impact logging sites. We will also compare our physical ly-based approach to both conventional (e.g., NDVI) and novel (e.g., SWIR-channel) vegetation indices as well as to linear mixture modeling methods. We will cross-compare these approaches using Hyperion and ALI imagers to determine the strengths and limitations of these two sensors for applications of forest biophysics. This effort will yield the first physical ly-based, quantitative analysis of the detection and intensity of selective logging in Amazonia, comparing hyperspectral and improved multi-spectral approaches as well as inverse modeling, linear mixture modeling, and vegetation index techniques.

Asner, Gregory P.↗

In situ microscopy of the self-assembly of branched nanocrystals in solution

Here, solution-phase self-assembly of nanocrystals into mesoscale structures is a promising strategy for constructing functional materials from nanoscale components. Liquid environments are key to self-assembly since they allow suspended nanocrystals to diffuse and interact freely, but they also complicate experiments. Real-time observations with single-particle resolution could have transformative impact on our understanding of nanocrystal self-assembly. Here we use real-time in situ imaging by liquid-cell electron microscopy to elucidate the nucleation and growth mechanism and properties of linear chains of octapod-shaped nanocrystals in their native solution environment. Statistical mechanics modelling based on these observations and using the measured chain-length distribution clarifies the relative importance of dipolar and entropic forces in the assembly process and gives direct access to the interparticle interaction. Our results suggest that monomer-resolved in situ imaging combined with modelling can provide unprecedented quantitative insight into the microscopic processes and interactions that govern nanocrystal self-assembly in solution.

77 NANOSCIENCE AND NANOTECHNOLOGY↗

Sci—Sat AM: Stereo — 01: 3D Pre-treatment Dose Verification for Stereotactic Body Radiation Therapy Patients

Radical treatment techniques such as stereotactic body radiation therapy (SBRT) are becoming popular and they involve delivery of large doses in fewer fractions. Due to this feature of SBRT, a high-resolution, pre-treatment dose verification method that makes use of a 3D patient representation would be appropriate. Such a technique will provide additional information about dose delivered to the target volume(s) and organs-at-risk (OARs) in the patient volume compared to 2D verification methods. In this work, we investigate an electronic portal imaging device (EPID) based pre-treatment QA method which provides an accurate reconstruction of the 3D-dose distribution in the patient model. Customized patient plans are delivered ‘in air’ and the portal images are collected using the EPID in cine mode. The images are then analysed to determine an estimate of the incident energy fluence. This is then passed to a collapsed-cone convolution dose algorithm which reconstructs a 3D patient dose estimate on the CT imaging dataset. To date, the method has been applied to 5 SBRT patient plans. Reconstructed doses were compared to those calculated by the TPS. Reconstructed mean doses were mostly within 3% of those in the TPS. DVHs of target volumes and OARs compared well. The Chi pass rates using 3%/3mm in the high dose region are greater than 97% in all cases. These initial results demonstrate clinical feasibility and utility of a robust, efficient, effective and convenient pre-treatment QA method using EPID. Research sponsored in part by Varian Medical Systems.

60 APPLIED LIFE SCIENCES↗

Analysis of radar images by means of digital terrain models

It is pointed out that the importance of digital terrain models in the processing, analysis, and interpretation of remote sensing data is increasing. In investigations related to the study of radar images, digital terrain models can have a particular significance, because radar reflection is a function of the terrain characteristics. A procedure for the analysis and interpretation of radar images is discussed. The procedure is based on a utilization of computer simulation which makes it possible to produce simulated radar images on the basis of a digital terrain model. The simulated radar images are used for the geometric and radiometric rectification of real radar images. A description of the employed procedures is provided, and the obtained results are discussed, taking into account a test area in Northern California.

Domik, G.↗

Planetary Image Geometry Library

The Planetary Image Geometry (PIG) library is a multi-mission library used for projecting images (EDRs, or Experiment Data Records) and managing their geometry for in-situ missions. A collection of models describes cameras and their articulation, allowing application programs such as mosaickers, terrain generators, and pointing correction tools to be written in a multi-mission manner, without any knowledge of parameters specific to the supported missions. Camera model objects allow transformation of image coordinates to and from view vectors in XYZ space. Pointing models, specific to each mission, describe how to orient the camera models based on telemetry or other information. Surface models describe the surface in general terms. Coordinate system objects manage the various coordinate systems involved in most missions. File objects manage access to metadata (labels, including telemetry information) in the input EDRs and RDRs (Reduced Data Records). Label models manage metadata information in output files. Site objects keep track of different locations where the spacecraft might be at a given time. Radiometry models allow correction of radiometry for an image. Mission objects contain basic mission parameters. Pointing adjustment ("nav") files allow pointing to be corrected. The object-oriented structure (C++) makes it easy to subclass just the pieces of the library that are truly mission-specific. Typically, this involves just the pointing model and coordinate systems, and parts of the file model. Once the library was developed (initially for Mars Polar Lander, MPL), adding new missions ranged from two days to a few months, resulting in significant cost savings as compared to rewriting all the application programs for each mission. Currently supported missions include Mars Pathfinder (MPF), MPL, Mars Exploration Rover (MER), Phoenix, and Mars Science Lab (MSL). Applications based on this library create the majority of operational image RDRs for those missions. A Java wrapper around the library allows parts of it to be used from Java code (via a native JNI interface). Future conversions of all or part of the library to Java are contemplated.

Deen, Robert C.↗